• Title/Summary/Keyword: In(III)

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Effects of Extract of Radix Achyranthis Bidentatae on Cadmium Inhalation Toxicity in Rats (우슬 추출물이 카드뮴 흡입폭로된 흰쥐의 독성해독에 미치는 영향)

  • Kim Hong Ki;Jeung Jaeyeal;Park Seung Jong;Kang Sung Ho;Song Young Sun;Lee Ki-Nam
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.2
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    • pp.474-483
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    • 2004
  • To know the effects between Cd inhalation toxicity and extract of Radix Achyranthis Bidentatae, 4 rat groups were exposed to Cd aerosol in air using whole-body inhalation exposure for 6 hours/day, 5 days/week, and 4 weeks. Cd concentration in air was 1.03㎎/㎥ and mass median diameter(MMD) was 1.69㎛. 3 different dose intraperitoneal injections of extract of Radix Achyranthis Bidentatae to 3 inhalation exposure groups was done for 4 weeks and the results were as follows: The highest body weight gain for 4 weeks and food intake per day were from inhalation exposure group I and the highest lung and liver weight were also from inhalation exposure group I. The highest kidney weight was from inhalation exposure group III. The lowest Cd content in lung was 33.49㎍/g from inhalation exposure group I. The lowest Cd concentration in blood was 9.36㎍/㎗ from inhalation exposure control. Cd concentrations of 40.02㎍/g in liver and 69.18㎍/g in kidney were the lowest from inhalation exposure group I and III, respectively. The lowest Cd concentration in liver was 21.08㎍/g from inhalation exposure group III and The lowest Cd concentration in kidney was 15.78㎍/g from inhalation exposure group II. For weekly Cd concentration in urine, the value of the fourth week from inhalation exposure group III was the highest. For weekly Cd concentration in feces, the value of the first week from inhalation exposure group III was the highest. The highest metallothionein concentration in lung was 53.42 ㎍/g from inhalation exposure group III and the highest metallothionein concentration in liver was 188.18㎍/g from inhalation exposure group III. The highest metallothionein concentration in kidney was 143.92㎍/g from inhalation exposure group III. The highest Hct, Hb, and WBC values were from inhalation exposure group II and the highest RBC value was from inhalation exposure group III.

Effect of Garlic (Allium sativum L.) Extracts on Formation of N-Nitrosodimethylamine (마늘 추출물이 N-Nitrosodimethylamine의 생성에 미치는 영향)

  • Choi, Sun-Young;Kim, Hyung-Sik;Lee, Soo-Jung;Shon, Mi-Yae;Shin, Jung-Hye;Sung, Nak-Ju
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.6
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    • pp.677-682
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    • 2006
  • This study was conducted to investigate the effect of garlic extracts on electron donating ability nitrite-scavenging activity and N-nitrosodimethylamine (NDMA) formation. Content of total phenolic compounds was the highest in ethyl acetate extract. Electron donating ability was significantly increased with increasing sample concentration, as $88.0{\pm}1.53%$ from ethyl acetate extract and $77.5{\pm}0.8%$ from butanol extract in concentration of 10 mg/mL. Butanol extract from garlic with highest nitrite scavenging activity and inhibition effect of NDMA formation exhibited $96.9{\pm}0.75%$ and $68.6{\pm}1.15%$ in concentration of 10 mg/mL, respectively. The butanol extract was fractionated into 5 fractions using prep-LC. Nitrite-scavenging activity and inhibition effect of NDMA formation were excellent in fraction III, which further fractioned into 3 subfractions (III-a, III-b and III-c) using prep-LC. Of the 3 subfractions, its activity was the highest in the subfraction III-c. Therefore butanol extract of garlic was suggested to be effective inhibitor of NDMA formation.

Synthesis and Properties of Ionic Polyacetylene Composite from the In-situ Quaternization Polymerization of 2-Ethynylpyridine Using Iron (III) Chloride (염화 철(III)을 이용한 2-에티닐피리딘의 in-situ4차염화중합을 통한 이온형 폴리아세틸렌 복합체의 합성과 특성)

  • Taehyoung Kim;Sung-Ho Jin;Jongwook Park;Yeong-Soon Gal
    • Applied Chemistry for Engineering
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    • v.35 no.4
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    • pp.296-302
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    • 2024
  • An ionic conjugated polymer-iron (III) chloride composite was prepared via in-situ quaternization polymerization of 2-ethynylpyridine (2EP) using iron (III) chloride. Various instrumental methods revealed that the chemical structure of the resulting conjugated polymer (P2EP)-iron (III) chloride composite has the conjugated backbone system having the designed pyridinium ferric chloride complexes. The polymerization mechanism was assumed to be that the activated triple bond of 2-ethynylpyridinium salt, formed at the first reaction step, is easily susceptible to the step-wise polymerization, followed by the same propagation step that contains the propagating macroanion and monomeric 2-ethynylpyridinium salts. The electro-optical and electrochemical properties of the P2EP-FeCl3 composite were studied. In the UV-visible spectra of P2EP-FeCl3 composite, the absorption maximum values were 480 nm and 533 nm, and the PL maximum value was 598 nm. The cyclic voltammograms of the P2EP-FeCl3 composite exhibited irreversible electrochemical behavior between the oxidation and reduction peaks. The kinetics of the redox process of composites were found to be very close to a diffusion-controlled process from the plot of the oxidation current density versus the scan rate.

Monensin Enriched Urea Molasses Mineral Block on Feed Intake, Nutrient Digestibility and Blood Glucose in Cattle Fed on Wheat Straw Based Diet

  • De, Debasis;Singh, G.P.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.11
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    • pp.1579-1584
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    • 2002
  • Twelve adult male crossbred (Sahiwal${\times}$Holstein Friesian) cattle were distributed into four groups of three each on body weight basis. Animals were given wheat straw as a basal diet. The animals of group I and II were supplemented with concentrate mixture and animals of group III and IV were supplemented with cold processed urea molasses mineral block (UMMB). Thirty mg monensin/day/animal was supplemented to the animals of group II and 35 ppm monensin were incorporated in the UMMB supplemented to the animals of group IV. Vit.A and D mixture was given to all the animals once a week. Dry matter (DM) intake (kg/d) through wheat straw was 19.0 percent higher in the UMMB (without monensin) supplemented group (group III) than those of the concentrate mixture (without monensin) supplemented group i.e. group I. Total DM intake (kg/d) was lower in the monensin supplemented groups than those of non-supplemented groups though differences were not statistically significant. Digestible dry matter, organic matter (OM), crude protein (CP) and total digestible nutrients (TDN) intake were similar in all the groups. Average block consumption for 45 d period in the group III (0.95 kg/d) and group IV (0.84 kg/d) did not differ significantly. DM digestibility (%) was significantly (p<0.01) higher in the group II (58.9) as compared to the group I (52.7) and group III (54.0) but similar to the group IV (57.2). OM digestibility was also significantly (p<0.05) higher in the group II (63.2) as compared to that of the group I (54.9) but similar to the group III (57.8) and IV (59.2). Ether extract (EE) digestibility was significantly (p<0.01) higher in the group I (76.9) and II (80.3) as compared to the group III (59.87) and IV (55.77). Nitrogen free extract (NFE) digestibility was significantly (p<0.05) higher in the group II (62.38) as compared to that of the other groups. Crude protein (CP) and crude fibre (CF) digestibilities were not affected either due to UMMB or monensin. Nitrogen balance did also not differ significantly among the groups. However, Ca and P balance (g/d) in the group III (3.1, 1.3) and IV (3.0, 1.4) were significantly (p<0.01) higher than those of the group I (0.6, 0.2) and II (0.4, 0.3). Blood glucose (mg/100ml) was significantly (p<0.01) higher in the group II (65.2) and IV (65.2) as compared to the group I (55.2) and group III (53.9). Plasma urea-N level (mg/100 ml) in the group III (19.0) and IV (17.8) were significantly (p<0.01) higher than that of the group I (10.5) and II (12.3). So, monensin supplementation either with cold process UMMB or concentrate mixture did not show any additional effect on feed intake and digestibility but increases blood glucose level in adult cattle.

Mode of Action and Chemical Modification of an Alkaline Xylanase (CX-III) from Alkalophilic Cephalosporium sp. RYM-202 (호알카리성 Cephalosporium sp. RYM-202로부터 분리된 alkaline xylanase (CX-III)의 작용 양상 및 화학적 변환)

  • Kang, Myoung-Kyu;Maeng, Pil-Jae;Rhee, Young-Ha
    • The Korean Journal of Mycology
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    • v.24 no.4 s.79
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    • pp.255-264
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    • 1996
  • The hydrolysis products formed from birchwood xylan by the action of an alkaline xylanase (CX-III) from alkalophilic Cephaloxporium sp. RYM-202 were xylobiose and xylooligosaccharides polymerized with more than 4 sugar molecules. This enzyme was not active on xylobiose but readily attacked xylotriose accumulating xylobiose as a major product. The predominant end-products from xylotetraose by CX-III were xylobiose and xylotriose. These results indicate that the enzyme is typically endo-type xylanase possessing transglycosidase activity. Chemical modification of CX-III with N-bromosuccinimide revealed that two tryptophan residues per molecule of CX-III were essential for its catalytic activity on xylan. On the other hand, iodoacetamide and diethylpyrocarbonate did not influence the activity of the enzyme, suggesting that cysteine and histidine residues are not involved in the active site of this alkaline xylanase.

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A Case of Pulmonary Thromboembolism Due to Congenital Antithrombin III Deficiency (선천성 Antithrombin III 결핍증에서 발생한 폐색전증 1 예)

  • Park, Hyeong-Kwan;Park, Chang-Min;Ko, Kyoung-Haeng;Rim, Myung-Soo;Kim, Yu-Il;Hwang, Jun-Hwa;Lim, Sung-Chul;Kim, Young-Chul;Park, Kyung-Ok
    • Tuberculosis and Respiratory Diseases
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    • v.47 no.3
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    • pp.394-399
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    • 1999
  • We report a case of congenital and familial antithrombin III deficiency developing massive pulmonary thromboembolism. A 44-year-old man was admitted to our hospital because of sudden chest pain and severe dyspnea. Five years ago, he was operated due to a mesenteric vein thrombosis of unknown cause. On admission, radioisotopic venogram showed deep vein thrombosis and lung scintigram showed multiple segmental perfusion defects. His plasma antithrombin III level was 10.5 mg/dL which was less than 50% of normal and those of a son and two daughters were also decreased. After treatment with tissue plasminogen activator, heparin and coumadin, his symptom and lung scintigram were significantly improved. As far as we reviewed, there were very rare reports with congenital antithrombin III deficiency presenting as pulmonary thromboembolism in Korea.

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Conservative Endodontic Treatment of Type III Dens Invaginatus : Case Report (Type III 치내치의 보존적 근관치료 : 증례보고)

  • Jo, Wansun;Lee, Nanyoung;Lee, Sangho
    • Journal of the korean academy of Pediatric Dentistry
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    • v.41 no.2
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    • pp.174-179
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    • 2014
  • Dens invaginatus is a developmental anomaly resulting from an infolding of the enamel organ into the dental papilla prior to calcification of the dental tissue. Clinical and radiographic presentation of dens invaginatus shows a lot of variation. The classification proposed by Oehlers(1957) is most commonly used among classifications of dens invaginatus. Several treatments have been suggested to treat Type III dens invaginatus where the pulp remains healthy but the invagination is associated with a periodontitis. The top priority objective is to preserve pulp as sound as possible. Thus, if there is no definite evidence of pulpal disease, the conservative access which treat invagination as distinct from the pulp is necessary. But, Endodontic treatment of Type III dens invaginatus has the particular problems associated with achieving adequate chemomechanical debridement of the root canal system and invagination, predictable length control and consistent filling. In this case report, the endodontic treatment limited within invagination was performed for treatment of Type III dens invaginatus, and filling with Mineral Trioxide Aggregate(MTA) resulted in good prognosis.

Removal of As(III) and As(V) in Aqueous Phases by Fe and Mn Oxides Coated Granular Activated Carbon (철 및 망간 산화물로 코팅된 입자활성탄을 이용한 수용액 중 As(III) 및 As(V)의 제거)

  • Lee, Hee-Yong;Yang, Jung-Seok;Choi, Jae-Young;Lee, Seung-Mok
    • Journal of Korean Society of Environmental Engineers
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    • v.31 no.8
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    • pp.619-626
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    • 2009
  • The objective of this study was to evaluate the efficiency of Fe and Mn oxides coated granular activated carbons (FMOCGs) for the removal of arsenite and arsenate by oxidation and adsorption mechanisms using surface characterization and batch adsorption experiments. Within four manufactured adsorbents, Fe and Mn contents of FMOCG-1 was the highest (178.12 mg Fe/g and 11.25 mg Mn/g). In kinetic results, As(III) was removed by oxidation and adsorption with FMOCGs. Removal of arsenic by FMOCGs increased as pH value of the solution decreased. The adsorption isotherm results were well fitted with Langmuir isotherm. Adsorption amount of As(V) onto FMOCGs was higher than that of As(III) and the maximum adsorption capacities of FMOCGs for As(III) and As(V) were 1.38~8.44 mg/g and 2.91~9.63 mg/g, respectively.