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Water Quality Variation and Removal Characteristics of Poliovirus by Biological Activated Carbon (BAC) and Ozone Treatment Process in Nakdong River. (낙동강 원수의 생물활성탄 및 오존처리공정에 따른 수질 변화 및 폴리오바이러스의 제거특성)

  • Jung Eun-Young;Park Hong-Ki;Lee You-Jung;Jung Jong-moon;Jung Mi-Eun;Hong Yong-Ki;Jang Kyoung-Lib
    • Journal of Life Science
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    • v.15 no.5 s.72
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    • pp.696-702
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    • 2005
  • Ozonation is a disinfection technique of harmful mi-crobes commonly used in the treatment of drinking water. And Biological Activated Carbon (BAC) treatment also provides numerous benefits for drinking water utilities, including removal of micro- pollutants, improved treatment processes. The multiful-stage ozonation and BAC play roles as effective methods for removing several materials in raw water. Water quality variation in Nak dong river and the removal efficiency of viruses by ozonation-BAC process were investigated on pilot scale. During the period of survey, most of water quality parameters including $NH_{4}^{+}-N$ were highly improved after passing through the BAC. The removal efficiency of poliovirus type III in water treatment process using pilot-plant,$ 99.6\% $ of viruses were removed by pre-ozonation, sedimentation and sand filteration process, $ 100\% $ were removed after in BAC filteration step. In the removal survey of viruses by ozonation, ap-proximately $ 61.1\% $ or polioviruses were inactivated by ozone of 0.4 mg/l within 5 min. and $ 100\% $ were inactivated by ozone of 0.8 mg/l over 10 min.

Studies on the Storage and Utilization of Sweetpotatoes (III) Gamma-Irradiation and Storage of Sweetpotatoes (고구마의 저장(貯藏) 및 이용(利用)에 관(關)한 연구(硏究) -제삼보(第三報) : 감마선조사(線照射)와 고구마의 저장(貯藏)-)

  • Choi, Eon-Ho;Park, Nou-Poung;Lee, Su-Rae;Kim, Ho-Sik
    • Applied Biological Chemistry
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    • v.10
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    • pp.63-68
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    • 1968
  • The effects of $^{60}Co-{\gamma}$ radiation on the change of composition and susceptibility to soft rot during the storage of sweetpototoes and the radioresistance of spores of the soft rot fungus were investigated and the following results were obtained. 1) Gamma-irradiation of sweetpotatoes caused the increase in water-soluble sugar content and the decrease in ascorbic acid content during the storage. 2) The rate of oxygen uptake in sweetpotato slices becomes higher as the dose increases. But the oxygen uptake in slices irradiated with higher doses decreases along with the color change as the time passes. 3) Irradiation with high doses (above $2.5{\times}10^5$ rad) brought about the increased susceptibility to soft rot decay as the chilling injury did in the storage of sweetpotatoes. 4) Average lethal dose for the spores of Rhizopus nigricans was $3.0{\times}10^5$ rad and the complete death required the level of $1.25{\times}10^6$ rad.

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Molecular Cloning, Characterization, and Expression Analysis of Chicken Δ-6 Desaturase

  • Kang, Xiangtao;Bai, Yichun;Sun, Guirong;Huang, Yanqun;Chen, Qixin;Han, Ruili;Li, Guoxi;Li, Fadi
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.1
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    • pp.116-121
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    • 2010
  • Long-chain polyunsaturated fatty acids (LC-PUFA) promote the development of brain and vision of the fetus, relieve inflammation, inhibit oral dysplasia of rumor cell, decrease the incidence of cardiovascular disease and regulate arrhythmia. ${\Delta}-6$ desaturase is the rate-limited enzyme in the desaturation process. This study reports the cloning, characterization and tissue expression of a ${\Delta}-6$ desaturase gene in the chicken. PCR primers were designed based on the predicted sequence of chicken ${\Delta}-6$ desaturase (accession number: XM421053) and used to isolate a cDNA fragment of 1,323 bp from chicken liver. Based on the 1,323 bp fragment an EST (BI390105) was obtained by BLAST. The EST and 5'nd of the 1,323 bp fragment were partially overlapped. Gene specific primers derived from the EST were used for amplification of the 5'nd. Another gene-specific primer derived from the 1,323 bp fragment was used for amplification of the 3'nd by 3'ACE. Then the three overlapping cDNA sequences obtained were assembled with DNAMAN software and a full-length ${\Delta}-6$ desaturase of 2,153 bp was obtained. The full-length cDNA contained an ORF of 1,335 bp with a 5'ntranslated region of 147 nucleotides followed by an ATG initiation codon. Stop codon TGA was at position 1,481-1,483 bp. The deduced amino acids shared an homology above 77% with bovine, mice, orangutan, rat and human. The protein sequence had three histidine-rich regions HDFGH (HisI region), HFQHH (HisII region) and HH (HisIII region), a cytochrome $b_{5}$-like domain containing a heme-binding motif and two transmembrane domains. Sequence analysis of the chicken genomic DNA revealed that the coding sequence of chicken ${\Delta}-6$ desaturase included 12 exons and 11 introns. Semi-quantitative RT-PCR showed that the ${\Delta}-6$ desaturase expression levels were in turn liver, spleen, pancreas, lung, breast muscle, heart, and abdominal fat. The expression of ${\Delta}-6$ desaturase in liver was significantly higher than that in breast muscle (p<0.01). The expression of ${\Delta}-6$ desaturase in lung was significantly higher than that in abdominal fat (p<0.01). This is the first clone of chicken ${\Delta}-6$ desaturase.

A study on the accuracy of profile change Prediction by video imaging (Power Ceph $^{\circledR}Ver$ 3.3) in Class III two jaw surgery patients (골격성 III급 부정교합을 가진 양악 수술 환자의 술후 측모 예측을 위한 Video imaging (Power $Ceph^{\circledR}$ Ver 3.3)의 정확도에 관한 연구)

  • Kwon, Mi-Jeong;Baik, Hyoung-Seon;Lee, Won You
    • The korean journal of orthodontics
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    • v.29 no.3 s.74
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    • pp.285-301
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    • 1999
  • There is a need for more accurate prediction in surgical orthodontic treatment. Video imaging is an important technology in planning orthognathic surgery and educating patients about the esthetic results after treatment. Preoperative and postoperative lateral cephalogram of 30 patients who had one piece Le Fort I osteotomy advancement and mandibular set back by bilateral intraoral vertical ramal osteotomy with or without genioplasty were used in this study. The computer generated soft tissue line drawing prediction were compared with the actual postoperative cephalograms .The results are as follows. 1. 14 variables showed Statistically significant differences from 24 variables between computer predicted profile and post operative profile 2. Most of the differences were found in the maxilla-related soft tissue landmarks. 3. The predicted results were more accurate in the groups who had small amount of mandibular set back. 4. The predicted results were more accurate in the groups who had no genioplasty. Most of these differences were within 2mm ranges. Therefore profile change prediction by video imaging could be considered clinically acceptable.

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Clinical Study on Relationship between Pattern Identifications and Heart Rate Variability (변증과 심박변이도의 상관성 연구)

  • Choi, Sang Ok;Park, Sun Young;Jeong, Hui Jin;Jung, So Youn;Ahn, Su Yeun;Kim, Kyoung Min;Kim, Young Kyun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.27 no.3
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    • pp.318-326
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    • 2013
  • This study was performed to investigate relationship between each pattern identification and heart rate variability(HRV) indices. We analyzed 201 subjects who participated in stroke check up. We classified the subjects into four groups of pattern identifications; Fire-Heat pattern(FH), Yin Deficiency pattern(YD), Qi Deficiency pattern(QD) and Dampness-Phlegm pattern(DP) that based on Korean Standard Pattern Identifications for Stroke-III. We investigated significance of HRV indices between each pattern identification and heart rate variability indices. The total number of the subject group was 201, whereas the groups were divided into four groups; Fire-Heat pattern group(n=47), Yin Deficiency pattern(n=65), Qi Deficiency pattern(n=33), and Dampness-Phlegm pattern(n=56). SDNN, TP, Ln(TP), VLF, Ln(VLF), LF, Ln(LF) and HF were significantly higher in the Fire-Heat pattern(FH) group than other groups of pattern identifications, but there was no differences among the Yin Deficiency group, the Qi Deficiency group and the Dampness-Phlegm group. Ln(HF), LF(NORM), HF(NORM) and LF/HF ratio were significantly higher in the Fire-Heat group than in the Qi Deficiency group. However, there was no significant differences among the Dampness-Phlegm group, the Yin Deficiency group, Fire-Heat group and the Qi Deficiency group. Through this study, we found out some significant relationships between each pattern identification group and HRV indices. The result of this study demonstrates that sympathetic nerve was more active in the Fire-Heat group than other groups.

The Effect of the Range of Motion Exercise on Powerlessness and Life Satisfaction in the Elderly (근관절운동이 노인의 무력감 정도에 미치는 영향)

  • 신재신
    • Journal of Korean Academy of Nursing
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    • v.23 no.1
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    • pp.107-117
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    • 1993
  • This study was a clinical Quasi-experiment to examine the effects of the range of motion exercise on powerlessness and life satisfaction among the E-Institutionalized elderly in Pusan. The purpose was to test the effect of the range of motion exercises on powerlessness and life satis-faction, and to examine the correlation between powerlessness and life satisfaction. The subjects for this study were 54 elderly people, both were over 60 and residing at I-Institution in Pusan. The research samples of 54 elderly were divided into an experimental and control group by matching randomized assignment. The instruments for this study were the Assessment Tool of Powerlessness in the elderly developed by Miller, Life satisfaction developed by Yoon Jin, and the Active-Passive Range of Motion Exercise Program which was developed and utilized by Shin, Jae-Shin. The data were collected from December 15, 1990 to November 1991. The paired t-test, t-test and ANCOVA were used to test hypothesis I and II, related to the Effect of the Range of Motion Exercises to powerlessness and life satisfaction. To identify the relationship of the range of motion exercises to powerlessness and life satisfaction, path analysis was done through multiple regression. The interrelationship of the variables was analyzed using t-test paired t-test. The results of the three hypothesis can be summarized as follows : 1. Hypothesis I -the experimental group which participated in the Range of Motion Exercise gets lower powerlessness score than that of the control group-was accepted by t-test (t = -3.40, p = .001) but not accepted by ANCOVA (F = .1, p =.96). 2. Hypothesis II - the experimental group which participated in the Range of Motion Exercise gets a higher Life Satisfaction Score than that of the control group-was not supported by t-test(t = 1.01, p = .316) but was accepted by ANCOVA (F = 4.39, p = .006). 3. Hypothesis III - if the powerlessness Score becomes higher, the Life Satisfaction Score will be-come lower - was accepted by Pearson Correlation Coefficient (pre-exercise : r : -.34, p=.006), (post exercise : r = -.06, p=.32) . The relation-ship between the score of powerlessness and life satisfaction was negatively correlated. The results obtained clearly showed that the effects of the range of motion exercises on powerlessness and life satisfaction are beneficial to the elderly The relation between the scores of powerlessness and life satisfaction was negatively correlated and the range of motion exercise had a direct influence to powerlessness. Therefore, it is concluded that the relationship between powerlessness and life satis-faction was not a causal one. Also it is concluded that the range of motion exercises can be applied as a nursing intervention to reduce powerlessness and to improve life satisfaction in the elderly.

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Empirical Study on the Validity of Construction Bond-related Litigations (건설보증(建設保證) 분쟁해결(紛爭解決)의 소송(訴訟) 유효성(有效性)에 관(關)한 실증적(實證的) 연구(硏究))

  • Kim, Jong-Seo;Choi, Jong-Soo;Lee, Jae-Seob
    • Korean Journal of Construction Engineering and Management
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    • v.7 no.6
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    • pp.99-111
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    • 2006
  • Of the numerious dispute resolution methods, Alternative Dispute Resolution(ADR) is the most highly recommended approach for the guarantee bond-related dispute. In reality, however, claims were not resolved satisfactorily through ADR because of the lack of reference materials for negotiation, thus those were frequently had to be resolved through litigation. The above fact implies that, it is required to seek an efficient way to resolve the bond-related claims prior to they progress to litigation. This research paper intensively investigated judicial precedents of 232 cases with regard to construction bond-related disputes that observed during the analysis period(2000-2004). According to the summary statistics, it turned out that litigation were time consuming and potential economic loss was tremendous; on average, it takes 1067 days(the longest case was 1965 days) for dispute resolution. It suggests that litigations should be discouraged considering the magnitude of potential loss of stake holders. Research results revealed that there are some significant differences between categories in some variables affecting to the rate of winning; i) the number of lawsuit deputies of a plaintiff (in the 1st trial), ii) dispute locations (in the 1st and 3rd trials), iii) contract price (in the 1st trial), iv) contractors' operating capability (in the 1st and 2nd trials). For the rest of variables, significance level between categories was too low for preparing efficient improvement plan. Despite the important implications drawn from the analysis, this research has limitation due to the several reasons such as data structure, the depth of Information, etc. Therefore, more systematic research should be followed in the future.

Current Treatment and Clinical Outcomes of Community Acquired Pneumonia According to Pneumonia Severity Index (Pneumonia Severity Index에 따른 원외획득폐렴 환자의 치료 현황 및 성과)

  • Park, Hyun-Hee;Ji, Eun-Hee;Lee, Young-Sok
    • Korean Journal of Clinical Pharmacy
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    • v.21 no.2
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    • pp.170-181
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    • 2011
  • Purpose: There is considerable variability in rates of hospitalization for patients with community-acquired pneumonia (CAP) in part because of physicians' uncertainty in assessing the severity of illness at presentation. The purpose of the study was to examine the current treatment patterns and factors influencing the Pneumonia Severity Index (PSI) and clinical outcomes in the patient with CAP. Method: The retrospective data collection of the patients with CAP was conducted and the data were reviewed. The collected data included demographic, clinical, laboratory and microbiological medical information. All patients were stratified into three risk groups according to PSI: low risk (PSI score I-II), moderate risk (III) and high risk (IV-V) groups. The examined treatment patterns were the appropriateness of admissions, category of antibiotics used. The prognostic factors associated with PSI and clinical outcomes were examined. Results: One hundred and six patients' medical data were reviewed. The overall appropriateness of admissions was low presenting many of patients were admitted or intensely treated in the hospital despite of lower risk of prognosis and treated with intravenous antibiotics instead of oral fluoroquinolones. Primary pneumonia pathogens were Klebsiella pneumoniae (27%) and Streptococcus pneumoniae (21.6%). Mean LOS was 8.5 days and was significantly longer (10.0days) (p<0.001) in high risk group. The patients with age >65 (p<0.001), diabetes mellitus (p<0.001), mental alteration (p<0.001), and/or $PaO_2$ <60 mmHg (p<0.001) had a tendency to have higher PSI. The prognostic factors associated with longer LOS were age >65 years (p=0.008), mental status alteration (p<0.001), dyspnea (p=0.002) and PSI score (p=0.001). The prognostic factors associated with mortality were congestive heart failure (p=0.038), systolic blood pressure <90 mmHg (p=0.002) and arterial pH <7.35 (p=0.013). Conclusion: Most of patients were found to over-utilize medical service according to appropriateness of admissions. The elderly, mentally altered patients with low $PaO_2$ had higher PSI score with increased risk of LOS. The mortality could be increased in the patient with disease state of congestive heart failure, high blood pressure, and/or acidosis.

The Time and Effect of Hypothermia in Early Stage of the Reversible Cerebral Focal Ischemic Model of Rat (백서의 가역성 뇌허혈 모형에서 저체온의 효과와 적용시기)

  • Choi, Byung-Yon;Jung, Byung-Woo;Song, Kwang-Chul;Park, Jin-Han;Kim, Seong-Ho;Bae, Jang-Ho;Kim, Oh-Lyong;Cho, Soo-Ho;Kim, Seung-Lae
    • Journal of Korean Neurosurgical Society
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    • v.29 no.2
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    • pp.167-179
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    • 2000
  • Objective : We studied to clarify the effective time zone of mild hypothermic neural protection during ischemia and/or reperfusion after middle cerebral artery occlusion. Methods : In a reversible cerebral infarct model which maintained reperfusion of blood flow after middle cerebral artery occlusion for two hours, the size of cerebral infarction, cerebral edema and the extent of neurological deficit were observed and analyzed for comparison between the control and the experimental groups under hypothermia($33.5^{\circ}C$). The temporalis muscle temperature was reduced to $33.5^{\circ}C$ by surface cooling for two hours during middle cerebral artery occlusion for study group I. The following groups applied hypothermia for two-hour periods after reperfusion : group II(0-2 hours), group III(2-4 hours), and group IV(4-6 hours). They were rewarmed to $36.5^{\circ}C$ until sacrified at 2, 4, 6, 12, and 24 hours after reperfusion. Control group was maintained at normothermia without hypothermia. Results : In the experimental groups with hypothermia, the average value of the size of cerebral infarction($mean{\pm}SD$) was $1.97{\pm}1.65%$, which was a remarkable reduction over that of the control, $4.93{\pm}3.79%$. In the control, a progressive increase was shown in the size of infarction from point of reperfusion to 6 hours after reperfusion without further changes in size afterward. Intra-ischemic hypothermia(group I) prevented ischemic injury but did not prevent reperfusion injury. Group II examplified the most neural protective effect in comparison to the control group and group IV(p<0.05). The cortex was more vulnerable to reperfusion injury than the subcortex. Mild hypothermia showed more neural protective effects on the cortex than subcortex. Conclusion : The most appropriate time zone for application of mild hypothermia was defined to be within four hours following reperfusion.

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Math-disliking Types and the Correlation Coefficients between Mathematical Achievements and Them-Focused on the 8th Graders (수학 기피유형의 분류 및 수학 성취 수준과의 상관성 연구)

  • Kim, Young-Kuk
    • Journal of Educational Research in Mathematics
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    • v.17 no.1
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    • pp.33-50
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    • 2007
  • Positive attitude toward mathematics is gaining bigger recognition as an important contributing factor to mathematical ability. As a strategy for strengthening affective domain and betterment of mathematics teaching and loaming, classifying students by their causes for liking or disliking mathematics can be an effective way In this study the author tried to devise methods to classify students by their types of math disliking and investigate correlations between mathematical achievements and these math-disliking types from a sample group of 8th graders. To identify the types of reasons why 8th graders dislike mathematics, a questionnaire with 30 items was made firstly. Then by applying the 'Factor analysis' of SPSS, the 30 items were divided into five partitions. Through abstraction of each partition, five math-disliking types, 'Competences', 'Basics', 'Confidences', 'Usefulness', and 'Teachers' were defined. They are expected to help teachers for describing each student's tendency of math-disliking. Further, correlation coefficients between mathematical achievements and each of the five math-disliking type were investigated against 4 groups which were made from sample group by the discrimination of gender and two levels (high and low) of mathematical achievements in cognitive area. As results, the following facts were found. (i) The trends of correlations between cognitive achievement and the five math disliking types were different across the 4 groups at statistically meaningful degrees. (ii) Most of the male students who had math-disliking types were proved to be in the low achievement level. But for the female students, only 50% of students who had math-disliking types were in the low achievement level. (iii) Compared to male students, higher portion of female students had math-disliking types despite their high achievement in cognitive area.

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