• The KIPS Transactions:PartB
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• v.8B no.6
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• pp.669-674
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• 2001

In order to reflect the aggregation situation in the aggregation process, aggregation based on situation assessment (ASA) method was proposed in [1]. It consists of the situation assessment model (SAM) and the ASA algorithm. In the SAM, the value of parameter, p, is transformed into the nearest integer value [1]. The integer-typed output of SAM is used as input for an aggregation. The integer-typed output of SAM indicates the current degree of aggregation situation. The ASA algorithm produces at most finite several aggregation results between min and max. In the sequel, the ASA method can not properly handle the applications with the more sophisticated aggregation results between min and max. In order to solve this problem, we propose two improved ASA (I-ASA) methods. In these I-ASA methods, we allow the value of parameter of SAM to be a real number, and suggest two improved ASA algorithms to make continuous aggregation results between min and max. These I-ASA methods can handle both a precise aggregation and an approximate aggregation. Therefore, when compared to the ASA method [1], the proposed I-ASA methods have advantages in that they can handle the applications with the more sophisticated aggregation results and can be used in the more general applications for aggregations.

• Bulletin of the Korean Chemical Society
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• v.35 no.8
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• pp.2381-2384
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• 2014

A solid-phase synthetic approach is reported for the synthesis of an ascorbic acid (ASA)-dipeptide conjugate that exhibited enhanced antioxidant activity. The N-terminal amino group of dipeptide (Ala-Ala) on a resin support was first activated by 1,1'-carbonyldiimidazole (CDI), and then reacted with an ASA derivative. The addition of a base, triethylamine (TEA), promoted nucleophilic acylation of ASA derivative and yielded a desired product (ASA-Ala-Ala) with enhanced purity, when cleaved from the resin. Compared to the approach where a C3 hydroxyl group of ASA was first activated with CDI and then reacted with the amino group of dipeptide on the resin, this new approach allowed a significant reduction of a total reaction time from 120 h to 8 h at $25^{\circ}C$. As-prepared ASA-dipeptide conjugate (ASA-Ala-Ala) showed improved antioxidant activity compared to ASA.

• Proceedings of the KAIS Fall Conference
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• 2007.05a
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• pp.112-115
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• 2007

Currently an increase in domestic sewage and industrial wastewater causes serious water pollution in Korea. To solve water pollution problems, conventional activated sludge (CAS) system is generally used in wastewater treatment plant but this process is so ineffective in nitrogen and phosphorus. Even if CAS system is the major process, it must be improved instantly so as to remove nitrogen and phosphorus. Otherwise, the serious water pollution problems can't be resolved with CAS system. Therefore this study focused on the comparison of the treatment characteristics between ASA system and CAS system. And also the mass balance of each process of ASA system. The results from operating advanced step aeration (ASA) system indicated that the removal efficiency of BOD, COD, and SS was 89.9%, 74.5%, and 89.0% respectively. In comparison, the removal efficiency of BOD, COD, and SS for CAS system was 89.5%, 71.8%, and 89.5% respectively. In addition to the results, the TN removal efficiency of ASA system was 76.5% comparing to 32.7% of CAS system. It was concluded that the TN removal efficiency of ASA system was 44% higher than CAS system. And the TP removal efficiency was 81.4% in ASA system comparing to 25.2% in CAS system. It also means that over 56% of TP was removed in ASA system comparing to CAS system.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.39 no.2
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• pp.162-169
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• 2011

The flight control system utilize RSS(Relaxed Static Stability) criteria in both longitudinal axes to achieve performance enhancements and improve stability. The aircraft using digital flight-by-wire flight control system receives aircraft flight conditions such as pitch, roll and yaw rate, normal acceleration from RSA(Rate Sensor Assembly) and ASA(Acceleration Sensor Assembly). These sensors has permissible measurement error related to system safety of an aircraft but, unexpected flight motions are happened by sensing errors such as offset, noise and etc. The unexpected pitch down tendency occurred by ASA sensor bias in 1g level flight with pilot hands-off. This paper addresses the design and verification of flight control law to improve of pitch down or up tendency caused by ASA sensor bias. The result of analysis and flight test reveals that pitch down tendency can be improved by pitch attitude feedback system.

• Journal of the Korean Operations Research and Management Science Society
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• v.29 no.1
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• pp.43-56
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• 2004

The purpose of clustering is to partition a set of objects into several clusters based on some appropriate similarity measure. In most cases, clustering is considered without any prior information on the number of clusters or the structure of the given data, which makes clustering is one example of very complicated combinatorial optimization problems. In this paper we propose a general-purpose clustering method that can determine the proper number of clusters as well as efficiently carry out clustering analysis for various types of data. The method is composed of two stages. In the first stage, two different hierarchical clustering methods are used to get a reasonably good clustering result, which is improved In the second stage by ASA(accelerated simulated annealing) algorithm equipped with specially designed perturbation schemes. Extensive experimental results are given to demonstrate the apparent usefulness of our ASA clustering method.

• Journal of Oral Medicine and Pain
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• v.30 no.3
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• pp.361-373
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• 2005

Occlusal appliance therapy has been proven to be very useful and effective in reducing signs and symptoms of patients with TMD. However, there are no reports about the masticatory efficiency of the occlusal appliance. The purpose of this study was, first, to investigate the masticatory efficiency of the conventional stabilization appliance experimentally in normal healthy subjects, by comparing it with that of their natural dentition; and, second, to develop a modified stabilization appliance as an attempt to increase masticatory efficiency. Eleven subjects (mean age 25.3 years, range from 23 to 33) participated in this study. Six were men and five were women. They were healthy and had complete or near―complete natural dentition, and did not present with signs or symptoms of TMD. Two kinds of occlusal appliances―the conventional flat maxillary stabilization appliance (i.e., FSA) and a modified maxillary stabilization appliance with additional anatomic structures on its occlusal surface (i.e., ASA)―were made for every subject. Subjects chewed peanuts that were selected as a food to test the three masticatory conditions of the natural dentition, the ASA, and the FSA. The number of chewing strokes was counted during each 1-minute chewing period. Chewed peanut boluses were recovered and their hardness was measured by texture analysis. Statistical tests were performed. The following results were obtained. 1. The masticatory efficiency of the FSA was 38.6 percent that of the natural dentition. The efficiency of the ASA was 78.2 percent that of the natural dentition. 2. The number of chewing strokes in the natural dentition condition was measured to be 1.5 strokes per second. It decreased to 90 percent in the ASA and FSA conditions. These results indicate that the ASA could serve an improved masticatory capacity as well as its therapeutic effects in TMD. A clinical application of the ASA should be considered to extend the management of TMD patients.

• Tuberculosis and Respiratory Diseases
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• v.51 no.5
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• pp.474-481
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• 2001

Mesalazine(5-Aminosalicylic acid,5-ASA), a component of Sulfasalazine (sulfapyridine bound to 5-ASA), is used to treat inflammatory bowel disease. Most adverse pulmonary effects caused by sulfasalazine have been attributed to sulfapyridine. However, lung toxicity associated with mesalazine(5-ASA) is rare. Here we report a case of eosinophilic pneumonia in a 44-year-old woman with ulcerative colitis, who was treated with mesalazine. She developed symptoms of a dry cough, mild night fever, and exertional dyspnea. Bilateral peripheral pulmonary infiltrates, peripheral blood eosinophilia, and histologic features were consistent with eosinophilic pneumonia. The symptoms improved quite rapidly after the discontinuation of mesalazine and initiation of steroid therapy. Therefore, adverse pulmonary reactions to mesalazine must be considered in a differential diagnosis of pulmonary involvement in patients with inflammatory bowel disease who are receiving with mesalazine therapy.

• Korean Journal of Pharmacognosy
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• v.43 no.1
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• pp.22-26
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• 2012

The aim of this study was to evaluate the anti-inlfammatory effect of the extract of Zanthoxylum schinifolium on ulcerative colitis induced by 3% dextran sulfate sodium in the rat. The experiment animals were divided into six groups: control (normal), DDS-induced colitis, 1 mg/kg, 15 mg/kg and 150 mg/kg of the extract of Z. schinifolium and 150 mg/kg of 5-aminosalicylic acid (5-ASA) as comparative drug. Anti-ulcerative colitis effect was evaluated pathologically by disease activity index (DAI), the change of weight and myeloperoxidase (MPO) in colon mucosa. Treatment with 15 mg/kg and 150 mg/kg of the extract of Z. schinifolium significantly improved the gain of body weight and DAI as clinical symptoms, and reduced MPO and $PGE_2$ level as biochemical index. Especially, 150 mg/kg of the extract of Z. schinifolium showed markedly more improvement than the same dose of 5-ASA in all kind of index such as MPO, $PGE_2$ and DAI. These results suggest that Z. schinifolium mediated anti-inflammatory action on colorectal sites may be a useful therapeutic approach to ulcerative colitis.

• Current Photovoltaic Research
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• v.8 no.3
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• pp.94-101
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• 2020

This study was trying to focus on achieving high efficiency of multi junction solar cell with thin film silicon solar cells. The proposed thin film Si-Ge/c-Si tandem junction solar cell concept with a combination of low-cost thin-film silicon solar cell technology and high-efficiency c-Si cells in a monolithically stacked configuration. The tandem junction solar cells using amorphous silicon germanium (a-SiGe:H) as an absorption layer of upper sub-cell were simulated through ASA (Advanced Semiconductor Analysis) simulator for acquiring the optimum structure. Graded Ge composition - effect of E_g profiling and inserted buffer layer between absorption layer and doped layer showed the improved current density (J_sc) and conversion efficiency (η). 13.11% conversion efficiency of the tandem junction solar cell was observed, which is a result of showing the possibility of thin film Si-Ge/c-Si tandem junction solar cell.

• Elastomers and Composites
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• v.51 no.3
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• pp.175-180
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• 2016

Influence of amino acidic chemical on properties of maleic anhydride-grafted ethylene-propylene-diene terpolymer/zinc oxide (EPDM-g-MAH/ZnO) composites was investigated. 4-Aminosalicylic acid (ASA), 4-amino-2-methoxybenzoic acid (AMBA), 12-aminolauric acid (ALA), and glutamine (Gln) were employed as the amino acidic chemicals. Though small quantity (0.5 phr) of the amino acidic chemical was added to the EPDM-g-MAH/ZnO composite, the properties were notably changed. By adding the amino acidic chemical, the percent crystallinity and apparent crosslink density were reduced. Order of the percent crystallinity was related to that of the $pK_a$ values of amino acidic chemicals. By adding the amino acidic chemical, the basic tensile properties were on the whole improved. The experimental results were explained by the $pK_a$ values of amino acidic chemicals, change of zinc ionomer formation, and interactions between the additive and EPDM-g-MAH chain.