• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.10
• /
• pp.5625-5629
• /
• 2013

Occurrence of breast cancer is related to genetic as well as cultural, environmental and life-style factors. Variations in diversity of these factors among different ethnic groups and geographical areas emphasize the immense need for studies in all racial-ethnic populations. The incidence of breast cancer in Pakistan is highest in Asians after Jews in Israel and 2.5 times higher than that in neighboring countries like Iran and India, accounting for 34.6% of female cancers. The Pakistani population is deficient in information regarding breast cancer etiology and epidemiology, but efforts done so far had suggested consanguinity as a major risk factor for frequent mutations leading to breast cancer and has also shed light on genetic origins in different ethnic groups within Pakistan. World-wide research efforts on different ethnicities have enhanced our understanding of genetic predisposition to breast cancer but despite these discoveries, 75% of the familial risk of breast cancer remains unexplained, highlighting the fact that the majority of breast cancer susceptibility genes remain unidentified. For this purpose Pakistani population provides a strong genetic pool to elucidate the genetic etiology of breast cancer because of cousin marriages. In this review, we describe the known breast cancer predisposition factors found in the local Pakistani population and the epidemiological research work done to emphasize the importance of exploring factors/variants contributing to breast cance, in order to prevent, cure and decrease its incidence in our country.

• Management Science and Financial Engineering
• /
• v.16 no.2
• /
• pp.115-138
• /
• 2010

People acknowledge that mobile technology has improved their lives in terms of convenience, flexibility, connectedness, and new freedom of choice. However, as people increase usage of technology, they may become frustrated, challenged, annoyed, and irritated with it. This is the main characteristic of mobile technology paradoxes. Once technology gets into people's daily life, which it already has, people will look for a way to minimize the dependency on the technology, as well as finding a way to use the technology to improve the quality of their life. The focus of this study is to understand the mobile technology paradoxes and to develop coping strategies. As mobile technology is already a part of people's daily life, it is inevitable that people need to utilize technology as part of their lifestyles. This study developed a research model regarding the relationship between mobile technology perception and choice of coping strategies, including personal risk propensity as a mediating factor. Discussion on the importance of the technology paradoxes for developing mobile solution and services from the customers' perspectives followed after hypotheses testing.

• The Journal of Industrial Distribution & Business
• /
• v.13 no.4
• /
• pp.1-14
• /
• 2022

Purpose: The purpose of the study is to explore the application of Augmented Reality (AR) technology to enhance interactivity and decision making via technology-enabled experience particularly, in the context of COVID-19. This study investigated effects of perceived utilitarian value, hedonic value, social value, and perceived risk on customer satisfaction with AR technology that are rarely examined in previous studies. Research design, data and methodology: Online survey data was used in the study. This study applied factor analysis and regression analysis to test the hypotheses and employed ANOVA and mediation effect analysis to explore additional findings. Results: The results suggested that customers' perceived usefulness, arousal, social preference, innovativeness, financial risk, and performance risk have statistically significant effect on customer satisfaction. Conclusions: The findings of the study provided managerial and policy implications to develop and advertise the introduction of AR technology with the emphasis on the practical and utilitarian benefits of the technology. The result of this study highlighted the importance of customer relationship management by providing advanced services to customers through AR technology. This study contributes to technology-enabled CRM literature by providing the empirical result to verify the assumption that AR technology can be an effective tool of firms' CRM strategy

• Journal of the Korean Society of Marine Environment & Safety
• /
• v.19 no.2
• /
• pp.145-154
• /
• 2013

HNS, including crude oil and products, shipments have increased. The risk analysis of HNS has assumed the importance, especially in maritime transportation area. There are various forms and kinds of HNS and the consequences of an accident are serious. In order to provide practical measures for preventing accidents, this study analyses the potential risks of HNS on maritime transportation accidents at domestic sea by using Event Tree Analysis. This study carries out risk assessment with F-N curve and risk matrix focusing on liquid cargo carriers (Oil and Products Tanker, Chemical Tanker, LPG/LNG Tanker, etc.). Explosion and sinking, suffocation indicate high consequence when on collision represent high probability. Improving human errors should be the main factor to mitigate risk on human lives.

• Journal of Fashion Business
• /
• v.1 no.2
• /
• pp.55-64
• /
• 1997

This study adapted OSL (Optimum Stimulation Level) to induce the customer's behavior, especially customer's fashion behavior. The purpose of the fashion advertisement was to accelerate the purchasing desire for the clothes by catching the customer's attention. OSL is one of the methods. OSL can satisfy customers' desires using the new stimulation that reveals a customer's individual characters. In general, women are more concern about fashion and sensitive to the clothes of new fashion than men. But nowadays, many of the men are also concern about their appearance and fashion. The differences between men and women in fashion behavior and in each factor, of OSL, especially a relationship between OSL factor and fashion behavior are researched in this study. Such differences analyzed to find the sources that can satisfy their various desires. This study was expected to provide good information to plan advertising strategy in unpredictable market situation. The subjects for this study were 308 male and female university students. Mehrabian and Russell (1974),s ASTS(Arousal Seeking Tendency Scale) was adapted to measure the OSL, and twenty questions regarding fashion leadership and clothing importance released by Kwon, Shin, Lee, are adapted to measure the fashion behavior. An ANOVA was used as statistical analyzing method to find out the difference between men and women in fashion behavior. The relationship between fashion behavior and difference between men and women in OSL factors were measured by MANOVA. Conclusions were as follows; 1. In consciousness degree of fashion leadership and clothing importance in the fashion behavior, women were higher than men. 2. There was a difference between men and women in OSL's each factors in "unusual stimuli" and "sensuality", but there is no significant statistical difference in factors of "change", "risk", "new environment". Therefore women are higher than men in the stimulation level of "unusual stimuli" and" sensuality". 3. Low element of OSL relating to fashion behavior is from "change" and "unusual stimuli". 4. For the relationship between OSL and fashion behavior, fashion leadership and clothing importance were recognized better in the group of higher level of "change" and "unusual stimuli" irrespective of sex. In the case of "change" which is one of OSL factors, High OSL groups were higher than low OSL groups in the consciousness level of the fashion leadership and clothing importance. In men's case, High OSL-Change groups were higher than Low OSL-Change groups in the fashion leadership, but there was no difference between two groups in the consciousness of the clothing importance. In the case of "Unusual Stimuli", High OSL groups were superior to Low OSL groups in the fashion leadership, but there was no significant difference between two groups in the clothing importance. In women's case, High OSL-Change groups were superior to Low OSL-Change groups. In the case of "Unusual Stimuli", High OSL groups were superior to Low OSL groups in the fashion leadership, but there was no difference between two groups in the clothing importance.

• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.6
• /
• pp.2991-2995
• /
• 2012

Background: India shows some of the highest rates of cervical cancer worldwide, and more than 70% of the population is living in rural villages. Prospective cohort studies to determine the risk factors for cervical cancer are very rare from low and medium resource countries. The aim of this study was to quantify the effect of risk factors related to cervical cancer in a rural setting in South India. Material and methods: Sociodemographic and reproductive potential risk factors for cervical cancer were studied using the data from a cohort of 30,958 women who constituted the unscreened control group in a randomised screening trial in Dindigul district, Tamilnadu, India. The analysis was accomplished with the Cox proportional hazard regression model. Results: Women of increasing age (HR=2.4; 95% CI: 1.6, 3.8 in 50-59 vs 30-39), having many pregnancies (HR=7.1; 1.0, 52 in 4+ vs 0) and no education (HR=0.6; 0.2, 0.7 in high vs none) were found to be at significantly increased risk of cervical cancer. Conclusion: This cohort study gives very strong evidence to say that education is the fundamental factor among the sociodemographic and reproductive determinants of cervical cancer in low resource settings. Public awareness through education and improvements in living standards can play an important role in reducing the high incidence of cervical cancer in India. These findings further stress the importance of formulating public health policies aimed at increasing awareness and implementation of cervical cancer screening programmes.

• Journal of Convergence Society for SMB
• /
• v.1 no.1
• /
• pp.45-53
• /
• 2011

There are always many kinds of risks in software development such as frequent changes of requirements. Especially those risks related to the software characteristic of non-visibility can be threat to the project success. That lead us to the need of process implementation to reduce and minimize those risks. Although, most of the organization recognizes the importance of risk management, actual implementation requires professional knowledge in this area. CMMI, the de facto standard in process reference model, also emphasizes on risk management process area but only provides goals and practices to be implemented, not detail procedure and methods. In this paper, we developed Risk management implementation model based on IDEAL, the process improvement model based on CMMI. The proposed model will help the organizations to implement risk management process which is proper to their situation in the factor of organization size and project characteristics.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.17
• /
• pp.7021-7027
• /
• 2014

Background: The problem of cancer, especially lung cancer, is very acute in Bangladesh. The present study was conducted to evaluate the risk of lung cancer among Bangladeshi people based on hereditary, socio-economic and demographic factors. Materials and Methods: This study was carried out in 208 people (patients-104, controls-104) from January 2012 to September 2013 using a structured questionnaire containing details of lung cancer risk factors including smoking, secondhand smoke, tobacco leaf intake, age, gender, family history, chronic lung diseases, radiotherapy in the chest area, diet, obesity, physical activity, alcohol consumption, occupation, education, and income. Descriptive statistics and testing of hypotheses were used for the analysis using SPSS software (version 20). Results: According to this study, lung cancer was more prevalent in males than females. Smoking was the highest risk factor (OR=9.707; RR=3.924; sensitivity=0.8872 and P<0.0001) followed by previous lung disease (asthma, tuberculosis etc.) (OR=7.095; RR=1.508; sensitivity=0.316 and P<0.0001)) for male patients. Highly cooked food (OR=2.485; RR=1.126; sensitivity=0.418 and P=0.004)) and also genetic inheritance (OR=1.93; RR=1.335; sensitivity=0.163 and P=0.138) demonstrated significant correlation with lung cancer as risk factors after these two and alcohol consumption was not prevalent. On the other hand, for female patients, tobacco leaf intake represented the highest risk (OR=2.00; RR=1.429; sensitivity= 0.667 and P=0.5603) while genetic inheritance and highly cooked food also correlate with lung cancer but not so significantly. Socioeconomic status and education level also play important roles in causing lung cancer. Some 78.5% male and 83.3% of female cancer patients were rural residents, while 58.2% lived at the margin or below the poverty line. Most male (39.8%) and female (50.0%) patients had completed only primary level education, and 27.6% male and 33.3% female patients were illiterate. Smoking was found to be more prevalent among the less educated persons. Conclusions: The results obtained in this study indicate the importance of creating awareness about lung cancer risk factors among Bangladeshi people and making appropriate access to health services for the illiterate, poor, rural people.

• Journal of Korean Tunnelling and Underground Space Association
• /
• v.26 no.4
• /
• pp.315-326
• /
• 2024

In this study, the Delphi method and AHP (analytic hierarchy process) were used to evaluate tunnel collapse risk from a comprehensive and multifaceted perspective. Influence factors were established through literature reviews, previous studies, and brainstorming sessions with expert groups, resulting in the construction of five main classification systems. A panel of 21 experts was formed, and three rounds of Delphi surveys were conducted to prevent errors and biases in the expert judgment process, thereby enhancing reliability. Ultimately, 14 influence factors were identified through CVR (content validity ratio) and COV (coefficient of variation) analyses of the experts' responses. Subsequently, the AHP method was applied to assess the relative importance of each influence factor and calculate the final composite weights. The timing of support and reinforcement had the highest priority, followed by groundwater inflow, joint conditions, support pattern levels, and auxiliary methods. These findings help identify the key factors affecting tunnel collapse risk and provide a foundation for developing strategies to improve tunnel safety.

• Parasites, Hosts and Diseases
• /
• v.62 no.3
• /
• pp.365-377
• /
• 2024

Exposure to storage mite (SM) and house dust mite (HDM) allergens is a risk factor for sensitization and asthma development; however, the related immune responses and their pathology have not been fully investigated. The HDMs Dermatophagoides farinae and Dermatophagoides pteronyssinus and SM Tyrophagus putrescentiae are potent allergens that induce asthma. Most SM-related studies have focused on the allergic reactions of individuals by measuring their immunoglobulin (Ig)E expression. Considering the limited research on this topic, the present study aims to investigate the differences in the immune responses induced by HDMs and SMs and histologically analyze lung tissues in a mouse asthma model to understand the differential effects of HDM and SM. The results revealed that all mite species induced airway inflammation. Mice challenged with T. putrescentiae had the highest airway resistance and total cell, eosinophil, and neutrophil counts in the bronchoalveolar lavage fluid (BALF). The SM-sensitized groups showed more severe lesions and mucus hypersecretions than the HDM-sensitized groups. Although the degree of HDM and SM exposure was the same, the damage to the respiratory lung tissue was more severe in SM-exposed mice, which resulted in excessive mucin secretion and increased fibrosis. Furthermore, these findings suggest that SM sensitization induces a more significant hypersensitivity response in mucosal immunity than HDM sensitization in asthma models.