• Journal of Periodontal and Implant Science
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• 제24권3호
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• pp.493-502
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• 1994

The benefits in using controlled delivery approaches include improved pharmacokinetic response, greater ability to localize the drung adjacent to the disease, and more control of local concentration at a lower total dosage. The purpose of this study was to evaluate the efficacy and safety of Minocline strip on chronic marginal periodontitis. Minocline Strip was applied in the periodontal pocket of 94 patients with a clinically diagnosed as a chronic marginal periodontitis, 4 sites for each patients with a 5mm probing pocket depth were selected in split mouth design and were divided into two group, ie., placebo group ($C_1$, $C_2$) and experimental group ($E_1$, $E_2$). Supragingival scaling and oral hygiene instruction were performed 1 week before experiment. Minocline Strip was applied on day 0 and 7, weekly, Clinical and microbiological tests were performed on day 0, 7, 14, 28 and 42. The results were as follows ; 1. Minocline Strip showed significant improvement on Chronic Marginal Periodontitis in 77 patients (82.0%) and improvement rate was more than 66.7% of all investigational items. 2. Only 6 patients complained mild pruritis during the early therapy but not needed discontinuence of the therapy. 3. The availability of Minocline Strip was 72 patients (76.6%) synthetically evaluating efficacy and safety. In conclusion, Minocline Strip appears to be effective and safe for the treatment of Chronic Marginal Periodontitis.

• 대한심미치과학회지
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• 제23권2호
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• pp.80-85
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• 2014

가지런한 치열을 얻기 위해 교정 치료는 치아 보존적인 의미에서 단연 First choice가 일 수 밖에 없다. 그러나 왜소치나 치아 크기의 불균형인 경우, 변색 치아나 파절, 심한 마모 치아인 경우 교정만으로는 심미적으로 완성도 높은 결과를 가져올 수 없다. 모든 치료에서 그러하지만, 특히 심미 치료에서는 치아 교정과 보철 치료, 혹은 치주 치료 및 임플란트등 항상 통합적인 진단과 치료계획이 필요한 경우가 많다. 그리고 다양한 치과 분야의 협진 진료가 필요한 환자에서는 안모와 치아의 심미적 만족뿐 아니라 기능적인 교합관계를 이룸으로써 장기간 안정적이며 조화로운 상태가 유지될 수 있는 치료가 전제되어야 한다. 본 증례는 전치부와 소구치에 cross bite가 있고, 상악 우중절치 절단에 마모가 있는 37세 여성 환자에서 교정과 라미네이트 수복치료를 동반한 경우이다. 치아교정을 통하여 전체적인 치아 위치를 재구성하여 기능교합을 이루었고, 최소한의 치질삭제로 라미네이트 수복치료를 함으로써 전치부 심미를 회복하였다. 최종 보철물을 장착하고 2년간 주기적인 follow up통해 예후를 관찰중이며, 부정교합의 재발이나 보철물 파절은 현재까지 관찰되지 않았다.

• Clinics in Shoulder and Elbow
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• 제14권1호
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• pp.99-104
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• 2011

목적: 주관절에 대한 인공 관절 성형술은 아직도 슬관절이나 고관절에서의 그것에 비해 정설이 정립되지 않은 분야이다. 치환물의 디자인이나 수술 술기면에서 많은 발전이 이루어지고 있지만, 여전히 문헌상 보고되는 장기 추시 결과는 많지 않은 실정이다. 여기에서는 현재 사용되고 있는 다양한 주관절 치환물에 대해 전반적으로 살펴보고자 하였다. 대상 및 방법: 주관절에 대한 인공 관절 성형술에 사용되는 치환물은 크게 3개로 분류되고 있다. 비구속형과 구속형, 그리고 전환 가능한 치환물이 그것이다. 이들 각각 치환물의 특징 및 현재의 경과 등에 대해 살펴보았다. 결과 및 결론: 주관절에 대한 인공 관절 성형술에 있어서 치환물의 형태 자체보다는 이를 적절히 적용하기 위한 적절한 환자의 선택, 지속적인 치환물 디자인의 개선, 수술 술기의 발달, 적절한 수술 후 재활 치료 등과 같은 요인 역시 중요하다.

• 대한음성언어의학회:학술대회논문집
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• 대한음성언어의학회 2003년도 제19회 학술대회
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• pp.181-181
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• 2003

Objectives : Vocal fold augmentation using injectable material is an easy and simple operation. This study is to evaluate the histology of minced and injected autologous auricular cartilage and fat graft in the augmentation of unilateral vocal fold paralysis using a canine model for two years. Study Design : A prospective study with the contralateral side of the larynx used as the control Methods : Twelve dogs were operated. At first, a piece of auricular cartilage was harvested from ear and minced into tiny chips with a scalpel and scissors. And also, a piece of fat tissue was harvested from inguinal area and minced into tiny chips with a scalpel and scissors. The minced cartilage and fat-paste (0.2ml) was injected using a pressure syringe into the paralyzed thyroarytenoid muscle under direct laryngoscopy. Two animals were sacrificed at 3 days, three at 3 weeks. two at 3 months. one at 6 months, one at 12 months, three at 24 months. Each dog underwent laryngectomy and serial coronal sections of paraffin blocks from the posterior part of the vocal fold were made. Result : There was no significant complication perioperatively and during follow-up. There was acute inflammatory findings in the graft at 3 days and 3 weeks. Only a very small proportion of the injected cartilage was absorbed due to the degenerative change and the overall volume was preserved even when the cells died out. The injected cartilage remained in the larynx until 24 months. Conclusion : The autologous cartilage implant using auricular cartilage was the ideal vocal cord augmentative material for the treatment of glottic incompetence.

• 한국표면공학회:학술대회논문집
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• 한국표면공학회 2018년도 춘계학술대회 논문집
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• pp.25-25
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• 2018

Electron beam melting (EBM) is one of powder based additive manufacturing technology used to produce parts for high geometrical complexity and directly with three-dimensional computer aided design (CAD) model. It is kind of the most promising methods with additive manufacturing for a wide range of medical applications, such as orthopedic, dental implant, and etc. This research has been investigated the microstructure and mechanical properties of as fabricated and hot iso-static pressing (HIP) processed specimens, which are made by an Arcam A1 EBM system. The Ti-6Al-4V titanium alloy powder was used as a material for the 3 dimensional printing specimens. Mechanical properties were conducted with EBM manufacturing and computer numerical control (CNC) machining specimens, respectively. Surface morphological analysis was conducted by scanning electron microscopy (SEM) for their surface, dissected plan, and fractured surface after tensile test. The mechanical properties were included tensile stress-strain and nano-indentation test as a analysis level between nano and macro. As following highlighted results, the stress-strain curves on elastic region were almost similar between as fabricated and HIP processed while the ductile (plastic deformed region) properties were higher with HIP than that of as fabricated processed.

• Journal of Periodontal and Implant Science
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• 제28권1호
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• pp.57-70
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• 1998

The purpose of this study was to evaluate the clinical and microbiological effects of metronidazole 25% dental gel that was applied to periodontal pockets who have moderate to advanced chronic adult periodontitis were selected for this study. The quadrants that had 2 or 3teeth with 5-8mm probing pocket depth were selected and divided into test side and control side according to the split-mouth design. The metronidazole 25% dental gel applied on test side and 0.12% chlorhexidine solution applicated on positive control side, normal saline irrigation into periodontal pocket was applicated to negative control side respectively. Above procedures followed scaling and root planing at baseline(0week). The subgingival sterile saline irrigation and chlorhexidine irrigation were done for about 30 seconds respectively. The metronidazole 25% dental gel was applied to periodontal pocket at 0,1 week in the test side. The clinical and microbiological analysis carried out at baseline(0week) and 4,8 weeks. The results of this study were as follows; 1. The sulcular bleeding index, probing pocket depth were significantly reduced in the test group. The relative proportions of spirochetes and motile rods were significantly reduced to negative control group and the proportion of cocci was correspondingly increased in the test group. 2. The sulcular bleeding index, probing pocket depth were significantly reduced in metronidazole group. and, there was a significant differences between 2 groups. Also, the relative proportions of spirochetes and motile rods were reduced in both group. And, there was a significant differences between 2 groups. In conclusion, application of metronidazole 25% dental gel as an adjunct to mechanical debridement of root surfaces may improved the clinical and microbiological status of periodontal disease sites.

• Journal of Periodontal and Implant Science
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• 제40권4호
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• pp.180-187
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• 2010

Purpose: This study evaluated the spontaneous healing capacity of surgically produced cranial defects in rabbits with different healing periods in order to determine the critical size defect (CSD) of the rabbit cranium. Methods: Thirty-two New Zealand white rabbits were used in this study. Defects of three sizes (6, 8, and 11 mm) were created in each of 16 randomly selected rabbits, and 15-mm defects were created individually in another 16 rabbits. The defects were analyzed using radiography, histologic analysis, and histometric analysis after the animal was sacrificed at 2, 4, 8, or 12 weeks postoperatively. Four samples were analyzed for each size of defect and each healing period. Results: The radiographic findings indicated that defect filling gradually increased over time and that smaller defects were covered with a greater amount of radiopaque substance. Bony islands were observed at 8 weeks at the center of the defect in both histologic sections and radiographs. Histometrical values show that it was impossible to determine the precise CSD of the rabbit cranium. However, the innate healing capacity that originates from the defect margin was found to be constant regardless of the defect size. Conclusions: The results obtained for the spontaneous healing capacity of rabbit cranial defects over time and the underlying factors may provide useful guidelines for the development of a rabbit cranial model for in vivo investigations of new bone materials.

• 대한의용생체공학회:의공학회지
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• 제17권1호
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• pp.61-70
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• 1996

In cementless total hip arthroplasty(THA), an initial stability of the femoral component is mandatory to achieve bony inyowth and secondary long term fixation. Primary stability of the femoral component can be obtained by minimizing the magnitude of relative micromotions at bone stem interface. An accurate evaluation of interf'ace micromotion and stress/strain fields in the bone-implant system may be relevant for better understanding of clinical situations and improving THA design. Recently finite element method(FEM) was introduced in'orthopaedic research field due to its unique capacity to evaluate stress in structure of complex shape, loading and material behavior. The authors developed the 3-dimensional finite element model of proximal femur with $Multilock^{TM}$ stem of 1179 blick elements to analyse the micromotions and mechanical behaviors at the bone-stem inteface in early post-operative period for the load simulating single leg stance. The results indicates that the values of relative motion for this well fit stem were $150{\mu}m$ in maximum $82{\mu}m$ in minimum and the largest relative motion was developed in medial region of Proximal femur and in anterior-posterior direction. The motion in the proximal bone was much greater than in the distal bone and the stress pattern showed high stress concentration on the cortex near the tip of the stem. These findings indicate that the loading on the hip joint in the early postoperative situation before achieving bony ingrowth could produce large micromotion of $150{\mu}m$ and clinicaly non-cemented THA patient should not be allowed weight bearing strictly early in the postoperative period.

• Journal of Periodontal and Implant Science
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• 제48권1호
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• pp.3-11
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• 2018

Purpose: This study utilized a strong quasi-experimental design to test the hypothesis that the implementation of a policy to expand dental care services resulted in an increase in the usage of dental outpatient services. Methods: A total of 45,650,000 subjects with diagnoses of gingivitis or advanced periodontitis who received dental scaling were selected and examined, utilizing National Health Insurance claims data from July 2010 through November 2015. We performed a segmented regression analysis of the interrupted time-series to analyze the time-series trend in dental costs before and after the policy implementation, and assessed immediate changes in dental costs. Results: After the policy change was implemented, a statistically significant 18% increase occurred in the observed total dental cost per patient, after adjustment for age, sex, and residence area. In addition, the dental costs of outpatient gingivitis treatment increased immediately by almost 47%, compared with a 15% increase in treatment costs for advanced periodontitis outpatients. This policy effect appears to be sustainable. Conclusions: The introduction of the new policy positively impacted the immediate and long-term outpatient utilization of dental scaling treatment in South Korea. While the policy was intended to entice patients to prevent periodontal disease, thus benefiting the insurance system, our results showed that the policy also increased treatment accessibility for potential periodontal disease patients and may improve long-term periodontal health in the South Korean population.

• 센서학회지
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• 제14권2호
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• pp.78-84
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• 2005

A contactless recharging device for totally implantable middle ear systems has been designed as a pillow type that the user can recharge the implanted battery with taking a rest. The proposed device uses the electromagnetic coupling between the transmitting coil and the receiving coil. To supply sufficient power for the implanted circuits, each coil uses LC resonance and the implanted device uses voltage doubler. A power MOSFET is used for switching the DC voltage of LC parallel circuit and the switching frequency demands on a programmable frequency generator which is controlled by microcontroller. In order to improve the electromagnetic coupling efficiency at specific positions of coil which may vary with the displacement of head, the optimal location of receiving coil was studied, and the 5 transmitting coils in a pillow for recharging the implant module was designed. From such a recharging experiment, it was found that the proposed device could provide the sufficient operating voltage within the distance of 4 cm between pillow and the implanted device.