• 한국지능시스템학회논문지
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• 제12권3호
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• pp.261-268
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• 2002

This paper represents that auto tunings of membership functions and weights in the fuzzy neural networks are effectively performed by immune algorithm. A number of hybrid methods in fuzzy-neural networks are considered in the context of tuning of learning method, a general view is provided that they are the special cases of either the membership functions or the gain modification in the neural networks by genetic algorithms. On the other hand, since the immune network system possesses a self organizing and distributed memory, it is thus adaptive to its external environment and allows a PDP (parallel distributed processing) network to complete patterns against the environmental situation. Also, it can provide optimal solution. Simulation results reveal that immune algorithms are effective approaches to search for optimal or near optimal fuzzy rules and weights.

• 대한전기학회논문지:시스템및제어부문D
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• 제52권8호
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• pp.471-481
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• 2003

The acts of biological immune system are similar to the navigation for autonomous mobile robots under dynamically changing environments. In recent years, many researchers have studied navigation algorithms using artificial immune networks. Conventional artificial immune algorithms consist of an obstacle-avoidance behavior and a goal-reaching behavior. To select a proper action, the navigation algorithm should combine the obstacle-avoidance behavior with the goal-reaching behavior. In this paper, the neural network is employed to combine the behaviors. The neural network is trained with the surrounding information. the outputs of the neural network are proper combinational weights of the behaviors in real-time. Also, a velocity control algorithm is constructed with the artificial immune network. Through a simulation study and experimental results for a autonomous mobile robot, we have shown the validity of the proposed navigation algorithm.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2002년도 ICCAS
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• pp.120.2-120
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• 2002

In this paper auto-tuning scheme of weight function in the neural networks has been suggested by immune algorithm for nonlinear process. A number of structures of the neural networks are considered as learning methods for control system. A general view is provided that they are the special cases of either the membership functions or the modification of network structure in the neural networks. On the other hand, since the immune network system possesses a self organizing and distributed memory, it is thus adaptive to its external environment and allows a PDP (parallel distributed processing) network to complete patterns against the environmental situation. Also. It can provi..

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2002년도 ICCAS
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• pp.106.5-106
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• 2002

1. Introduction 2. Artificial Immune Networks and Navigation Algorithm 3. Obstacle Avoidance and Goal Approach Behavior 4. Weights Adjustment Using Neural Network 5. Velocity Control and Local Minimum Avoidance 6. Simulation 7. Conclusion

• 대한전기학회논문지:시스템및제어부문D
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• 제51권9호
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• pp.402-412
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• 2002

The navigation algorithms enable autonomous mobile robots to reach given target points without collision against obstacles. To achieve safe navigations in unknown environments, this paper presents an effective navigation algorithm for the autonomous mobile robots with ultrasonic sensors. The proposed navigation algorithm consists of an obstacle-avoidance behavior, a target-reaching behavior and a fuzzy-based decision maker. In the obstacle-avoidance behavior and the target-reaching behavior, artificial immune networks are used to select a proper steering angle, make the autonomous mobile robot avoid obstacles and approach a given target point. The fuzzy-based decision maker combines the steering angles from the target-reaching behavior and the obstacle-avoidance behavior in order to steer the autonomous mobile robot appropriately. Simulational and experimental results show that the proposed navigation algorithm is very effective in unknown environments.

• 대한전기학회논문지:시스템및제어부문D
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• 제52권12호
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• pp.679-688
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• 2003

In order to navigate the mobile robots safely in unknown environments, many researches have been studied to devise navigational algorithms for the mobile robots. In this paper, we propose a navigational algorithm that consists of an obstacle-avoidance behavior module, a goal-approach behavior module and a radial basis function network(RBFN) supervisor. In the obstacle-avoidance behavior module and goal-approach behavior module, the fuzzy-artificial immune networks are used to select a proper steering angle which makes the autonomous mobile robot(AMR) avoid obstacles and approach the given goal. The RBFN supervisor is employed to combine the obstacle-avoidance behavior and goal-approach behavior for reliable and smooth motion. The outputs of the RBFN are proper combinational weights for the behavior modules and velocity to steer the AMR appropriately. Some simulations and experiments have been conducted to confirm the validity of the proposed navigational algorithm.

• IMMUNE NETWORK
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• 제13권2호
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• pp.43-54
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• 2013

Over the past 40 years, flow cytometry has emerged as a leading, application-rich technology that supports high-resolution characterization of individual cells which function in complex cellular networks such as the immune system. This brief overview highlights advances in multiparameter flow cytometric technologies and reagent applications for characterization and functional analysis of cells modulating the immune network. These advances significantly support highthroughput and high-content analyses and enable an integrated understanding of the cellular and molecular interactions that underlie complex biological systems.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제13권5호
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• pp.2732-2753
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• 2019

With the application of wireless sensor networks in the fields of ecological observation, defense military, architecture and urban management etc., the security problem is becoming more and more serious. Characteristics and constraint conditions of wireless sensor networks such as computing power, storage space and battery have brought huge challenges to protection research. Inspired by the danger theory in biological immune system, this paper proposes an intrusion detection model for wireless sensor networks. The model abstracts expressions of antigens and antibodies in wireless sensor networks, defines meanings and functions of danger signals and danger areas, and expounds the process of intrusion detection based on the danger theory. The model realizes the distributed deployment, and there is no need to arrange an instance at each sensor node. In addition, sensor nodes trigger danger signals according to their own environmental information, and do not need to communicate with other nodes, which saves resources. When danger is perceived, the model acquires the global knowledge through node cooperation, and can perform more accurate real-time intrusion detection. In this paper, the performance of the model is analyzed including complexity and efficiency, and experimental results show that the model has good detection performance and reduces energy consumption.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1997년도 한국자동제어학술회의논문집; 한국전력공사 서울연수원; 17-18 Oct. 1997
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• pp.124-127
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• 1997

In this paper, we propose a method of cooperative control based on immune system in distributed autonomous robotic system(DARS). Immune system is living body's self-protection and self-maintenance system. Thus these features can be applied to decision making of optimal swarm behavior in dynamically changing environment. For the purpose of applying immune system to DARS, a robot is regarded as a B lymphocyte(B cell), each environmental condition as an antigen, and a behavior strategy as an antibody respectively. The executing process of proposed method is as follows. When the environmental condition changes, a robot selects an appropriate behavior strategy. And its behavior strategy is simulated and suppressed by other robot using communication. Finally much simulated strategy is adopted as a swarm behavior strategy. This control scheme is based on clonal selection and idiotopic network hypothesis. And it is used for decision making of optimal swarm strategy.

• Asian Pacific Journal of Cancer Prevention
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• 제14권3호
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• pp.1731-1735
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• 2013

Objective: We aimed to identify key genes, pathways and function modules in the development of diffuse large B-cell lymphoma (DLBCL) with microarray data and interaction network analysis. Methods: Microarray data sets for 7 DLBCL samples and 7 normal controls was downloaded from the Gene Expression Omnibus (GEO) database and differentially expressed genes (DEGs) were identified with Student's t-test. KEGG functional enrichment analysis was performed to uncover their biological functions. Three global networks were established for immune system, signaling molecules and interactions and cancer genes. The DEGs were compared with the networks to observe their distributions and determine important key genes, pathways and modules. Results: A total of 945 DEGs were obtained, 272 up-regulated and 673 down-regulated. KEGG analysis revealed that two groups of pathways were significantly enriched: immune function and signaling molecules and interactions. Following interaction network analysis further confirmed the association of DEGs in immune system, signaling molecules and interactions and cancer genes. Conclusions: Our study could systemically characterize gene expression changes in DLBCL with microarray technology. A range of key genes, pathways and function modules were revealed. Utility in diagnosis and treatment may be expected with further focused research.