• Current Optics and Photonics
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• v.7 no.6
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• pp.745-754
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• 2023

In order to test the recognition ability and accuracy of a target imaging simulator under the irradiation of solar stray light in a laboratory environment, it needs to be fixed on a five-axis turntable during a hardware-in-the-loop simulation test, so the optical system of the simulator should have a long exit pupil distance. This article adopts a secondary imaging method to design a projection optical system suitable for thin-film-transistor liquid crystal displays. The exit pupil distance of the entire optical system is 1,000 mm, and the final optimization results in the 400 nm-850 nm band show that the modulation transfer function (MTF) of the optical system is greater than 0.8 at the cutoff frequency of 72 lp/mm, and the distortion of each field of view of the system is less than 0.04%. Combined with the design results of the optical system, TracePro software was used to model the optical system, and the simulation of the target imaging simulator at the magnitude of -1 to +6 Mv was analyzed and verified. The magnitude error is less than 0.2 Mv, and the irradiance uniformity of the exit pupil surface is greater than 90%, which meets the requirements of the target imaging simulator.

• Medical Lasers
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• v.10 no.3
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• pp.123-131
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• 2021

Optical imaging modalities with properties of real-time, non-invasive, in vivo, and high resolution for image-guided surgery have been widely studied. In this review, we introduce two optical imaging systems, that could be the core of image-guided surgery and introduce the system configuration, implementation, and operation methods. First, we introduce the optical coherence tomography (OCT) system implemented by our research group. This system is implemented based on a swept-source, and the system has an axial resolution of 11 ㎛ and a lateral resolution of 22 ㎛. Second, we introduce a fluorescence imaging system. The fluorescence imaging system was implemented based on the absorption and fluorescence wavelength of indocyanine green (ICG), with a light-emitting diode (LED) light source. To confirm the performance of the two imaging systems, human malignant melanoma cells were injected into BALB/c nude mice to create a xenograft model and using this, OCT images of cancer and pathological slide images were compared. In addition, in a mouse model, an intravenous injection of indocyanine green was used with a fluorescence imaging system to detect real-time images moving along blood vessels and to detect sentinel lymph nodes, which could be very important for cancer staging. Finally, polarization-sensitive OCT to find the boundaries of cancer in real-time and real-time image-guided surgery using a developed contrast agent and fluorescence imaging system were introduced.

• Current Optics and Photonics
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• v.3 no.3
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• pp.227-235
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• 2019

With slimmer, lighter and all-reflective imaging systems in high demand for consumer and military applications, coaxially folded optical image systems are widely considered because they can extend focal length and reduce track length. Most of these systems consist of multiple surfaces, and these surfaces are machined on one element or grouping processing on two elements. In this paper, we report and first experimentally demonstrate an all-aluminum all-reflective optical system which consists of two optical elements, with two high order aspherical surfaces in each element. The coaxially folded system is designed with Seidel aberration theory and advanced optimization with Zemax. The system is made of all-aluminum material processing by single point diamond turning (SPDT). On this basis, we completed the system integration and performed an imaging experiment. The final system has the advantages of short track length and long focal length and broad application prospects in the micro-unmanned aerial vehicle field.

• Current Optics and Photonics
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• v.5 no.2
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• pp.147-154
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• 2021

Microfluidic chip technology is a research focus in biology, chemistry, and medicine, for example. However, microfluidic chips are rarely applied in imaging, especially in ghost imaging. Thus in this work we propose a ghost-imaging system, in which we deploy a novel microfluidic chip modulator (MCM) constructed of double-layer zigzag micro pipelines. While in traditional situations a spatial light modulator (SLM) and supporting computers are required, we can get rid of active modulation devices and computers with this proposed scheme. The corresponding simulation analysis verifies good feasibility of the scheme, which can ensure the quality of data transmission and achieve convenient, fast ghost imaging passively.

• Journal of the Optical Society of Korea
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• v.14 no.1
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• pp.1-13
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• 2010

This paper describes a development of a fiber optic common-path optical coherence tomography (OCT) based imaging and guided system that possess ability to reliably identify optically transparent targets that are on the micron scale; ability to maintain a precise and safe position from the target; ability to provide spectroscopic imaging; ability to imaging biological target in 3-D. The system is based on a high resolution fiber optic Common-Path OCT (CP-OCT) that can be integrated into various mini-probes and tools. The system is capable of obtaining >70K A-scan per second with a resolution better than $3\;{\mu}m$. We have demonstrated that the system is capable of one-dimensional real-time depth tracking, tool motion limiting and motion compensation, oxygen-saturation level imaging, and high resolution 3-D images for various biomedical applications.

• Current Optics and Photonics
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• v.6 no.3
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• pp.260-269
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• 2022

Segmented planar imaging detector for electro-optical reconnaissance (SPIDER) is an emerging technology for optical imaging. However, this novel detection approach is faced with degraded imaging quality. In this study, a 6 × 6 planar waveguide is used after each lenslet to expand the field of view. The imaging principles of field-plane waveguide structures are described in detail. The local multiple-sampling simulation mode is adopted to process the simulation of the improved imaging system. A novel image-reconstruction algorithm based on deep learning is proposed, which can effectively address the defects in imaging quality that arise during image reconstruction. The proposed algorithm is compared to a conventional algorithm to verify its better reconstruction results. The comparison of different scenarios confirms the suitability of the algorithm to the system in this paper.

• Current Optics and Photonics
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• v.4 no.1
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• pp.1-8
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• 2020

We research a system of compressed-sensing computational ghost imaging (CSCGI) based on the intensity fluctuation brought by turbulence. In this system, we used the gamma-gamma intensity-fluctuation model, which is commonly used in transmission systems, to simulate the CSCGI system. By setting proper values of the parameters such as transmission distance, refractive-index structure parameter, and sampling rates, the peak signal-to-noise ratio (PSNR) performance and bit-error rate (BER) performance are obtained to evaluate the imaging quality, which provides a theoretical model to further research the ghost-imaging algorithm.

• Nuclear Medicine and Molecular Imaging
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• v.43 no.4
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• pp.344-351
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• 2009

Purpose: Optical imaging is providing great advance and improvement in genetic and molecular imaging of animals and humans. Optical imaging system consists of optical imaging devices, which carry out major function for monitoring, tracing, and imaging in most of molecular in-vivo researches. In bio-luminescent imaging, small animals containing luciferase gene locally irradiate light, and emitted photons transmitted through skin of the small animals are imaged by using a high sensitive charged coupled device (CCD) camera. In this paper, we introduced optical imaging system for the image acquisition of bio-luminescent signals emitted from small animals. Materials and Methods: In the system, Nikon lens and four LED light sources were mounted at the inside of a dark box. A cooled CCD camera equipped with a control module was used. Results: We tested the performance of the optical imaging system using effendorf tube and light emitting bacteria which injected intravenously into CT26 tumor bearing nude mouse. The performance of implemented optical imaging system for bio-luminescence imaging was demonstrated and the feasibility of the system in small animal imaging application was proved. Conclusion: We anticipate this system could be a useful tool for the molecular imaging of small animals adaptable for various experimental conditions in future.

• Proceedings of the KIEE Conference
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• 2003.11c
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• pp.488-491
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• 2003

Biochip-based diagnostic technology is an effective, time- and money- saving way. But, biochip analyzer including CCD imaging system has a complete optical system. It is one of reasons that the cost of biochip analyzer is expensive with CCD imaging system. In this paper, We suggested the simple and effective optical system for biochip analyzer with CCD imaging system. It consists of two parts with the same structure but opposite direction. Each part consists of achromatic doublet and meniscus. Suggested optical system has less lenses than existing system and more efficiently.

• Korean Journal of Optics and Photonics
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• v.25 no.1
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• pp.14-20
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• 2014

The equivalent of a thick lens is a lens which has the same power of refraction and paraxial imaging characteristics for a reference ray, but with a different axial thickness. In this study, thick lenses of an optical system were converted to their equivalent lenses referenced to pupil imaging. Aberration changes due to the lens conversion were compared to the general equivalent lens conversion referenced to object imaging.