• Title/Summary/Keyword: Il-Young Ahn

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Extraction & Separation Behavior of Light Rare Earth Elements from the Mixed Solutions by Cyanex 572 (경희토류(La, Ce, Pr, Nd, Sm) 혼합용액에서 Cyanex 572에 의한 추출·분리 거동 고찰)

  • Cho, Yeon-Chul;Lee, Joo-Eun;So, Hong-Il;Ahn, Jae-Woo;Kim, Hong-In;Lee, Jin-Young
    • Resources Recycling
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    • v.26 no.4
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    • pp.79-87
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    • 2017
  • Extraction and separation behaviors of La, Ce, Pr, Nd and Sm from light rare earth multi - component mixed solutions by Cyanex 572 were studied. As extractant concentration increased, the $pH_{50}$ values of all the five components decreased. When extractant concentration was larger than 0.6 M, the separation factor of La and Ce, Nd and Sm was higher than 10, while the separation factor between Ce and Pr, Pr and Nd was as low as 0.5~2.2. Addition of TBP to the 0.6 M Cyanex 572 had little synergistic effect on the phase separation rate and separation factor. From the analysis of experiment results, group separation of [La]/[Pr, Nd, Sm] and [Pr, Nd]/[Sm] could be possible, but in case of the group separation between [La, Ce] and [Pr, Nd] was not available because of the low separation factor between Ce and Pr.

Design of Counter current Extraction Process for the Separation of [Pr, Nd, Sm]/[La] using Cyanex 572 (Cyanex 572를 사용하여 [Pr, Nd, Sm]/[La]분리에 대한 향류추출공정 설계)

  • Lee, Joo-eun;So, Hong-Il;Jang, In-Hwan;Ahn, Jae-Woo;Kim, Hong-in;Lee, Jin-young
    • Resources Recycling
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    • v.27 no.4
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    • pp.50-56
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    • 2018
  • For the purpose of optimizing the counter current extraction process for separation of [Pr, Nd, Sm] group and [La] in mixed solution using Cyanex 572 as an extractant, the theory of Xu Guangxian was derived for calculating the optimized extraction factors. From the basic batch test result, the separation factor was 16.80 at extraction process and 21.48 at scrubbing process, and the loading capacity of 1.0 M Cyanex 572 was 0.12 M of rare earth element. The process parameters such as the stage number at extraction and scrubbing process, the flow rate ratio of feed and solvent solution can be calculated using an equation of optimum extraction ratio proposed by Xu Guangxian. From the result of calculation, 7 extraction stages and 4 scrubbing stages were required for rare earth separation, and the flow rate ratio of feed solution, solvent solution, scrubbing solution was 25 : 5.67 : 12.27.

Inhibitory effect of Korean Red Ginseng on melanocyte proliferation and its possible implication in GM-CSF mediated signaling

  • Oh, Chang Taek;Park, Jong Il;Jung, Yi Ra;Joo, Yeon Ah;Shin, Dong Ha;Cho, Hyoung Joo;Ahn, Soo Mi;Lim, Young-Ho;Park, Chae Kyu;Hwang, Jae Sung
    • Journal of Ginseng Research
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    • v.37 no.4
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    • pp.389-400
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    • 2013
  • Korean Red Ginseng (KRG) has been reported to exert anticancer, anti-oxidant, and anti-inflammatory effects. However, there has been no report on the effect of KRG on skin pigmentation. In this study, we investigated the inhibitory effect of KRG on melanocyte proliferation. KRG extract (KRGE) at different concentrations had no effect on melanin synthesis in melan-A melanocytes. Saponin of KRG (SKRG) inhibited melanin content to 80% of the control at 100 ppm. Keratinocyte-derived factors induced by UV-irradiation were reported to stimulate melanogenesis, differentiation, proliferation, and dendrite formation. In this study, treatment of melan-A melanocytes with conditioned media from UV-irradiated SP-1 keratinocytes increased melanocyte proliferation. When UV-irradiated SP-1 keratinocytes were treated with KRGE or SKRG, the increase of melanocyte proliferation by the conditioned media was blocked. Granulocyte-macrophage colony-stimulating factor (GM-CSF) was produced and released from UV-irradiated keratinocytes. This factor has been reported to be involved in regulating the proliferation and differentiation of epidermal melanocytes. In this study, GM-CSF was significantly increased in SP-1 keratinocytes by UVB irradiation ($30mJ/cm^2$), and the proliferation of melan-A melanocytes increased significantly by GM-CSF treatment. In addition, the proliferative effect of keratinocyte-conditioned media on melan-A melanocytes was blocked by anti-GM-CSF treatment. KRGE or SKRG treatment decreased the expression of GM-CSF in SP-1 keratinocytes induced by UVB irradiation. These results demonstrate that UV irradiation induced GM-CSF expression in keratinocytes and KRGE or SKRG inhibited its expression. Therefore, KRG could be a good candidate for regulating UV-induced melanocyte proliferation.

Degradation effect of carbendazim in soil by application with the microbial agent, Rhodococcus sp. 3-2 (미생물제(Rhodococcus sp. 3-2) 처리에 따른 토양 중 카벤다짐의 분해효과)

  • Yeon, Jehyeong;Kim, Hyeon-su;Ahn, Jae-Hyung;Han, Gui Hwan;Oh, Young Goun;Cho, Il Kyu;Park, In-Cheol
    • Korean Journal of Environmental Agriculture
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    • v.40 no.4
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    • pp.322-329
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    • 2021
  • BACKGROUND: The fungicide of benomyl, a benzimidazole group, has been commonly used for pesticides against fungal diseases in the world. However, benomyl is rapidly hydrolyzed in the environment after using to control plant diseases and has adverse effects by generating carbendazim, which is toxic to plants, humans, and the environment. METHODS AND RESULTS: In this study, the decomposition effect of carbendazim, a degradation product of benomyl was conducted in pot and field after making a prototype of benomyl-degrading microbial agent (BDMA). We found that the carbendazim-degrading microbial agent (CDMA) (105, 106, and 107 cfu/g soil) decomposed carbendazim by 50% or more in all the treatments, compared to the untreated control in the pot tests after four weeks. The effect of 100% decomposition of carbendazim was observed at 7 days after treatment, when the prototype of BDMA was apllied at 10-folds dilution in the field. The decomposition effect at more than 60% and plant growth promoting effect were observed after 7 days of the treatment, compared with the untreated group in the second field experiment,treated with commercially available concentrations of 500-folds and 1,000-folds. CONCLUSION(S): These results might represent that the BDMA would decompose carbendazim effectively, a decomposition product of the fungicide benomyl, remaining in agricultural area, and it could be utilized practically by using a low dilution rate.

Detrending Crop Yield Data for Improving MODIS NDVI and Meteorological Data Based Rice Yield Estimation Model (벼 수량 자료의 추세분석을 통한 MODIS NDVI 및 기상자료 기반의 벼 수량 추정 모형 개선)

  • Na, Sang-il;Hong, Suk-young;Ahn, Ho-yong;Park, Chan-won;So, Kyu-ho;Lee, Kyung-do
    • Korean Journal of Remote Sensing
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    • v.37 no.2
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    • pp.199-209
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    • 2021
  • By removing the increasing trend that long-term time series average of rice yield due to technological advancement of rice variety and cultivation management, we tried to improve the rice yield estimation model which developed earlier using MODIS NDVI and meteorological data. A multiple linear regression analysis was carried out by using the NDVI derived from MYD13Q1 and weather data from 2002 to 2019. The model was improved by analyzing the increasing trend of rime-series rice yield and removing it. After detrending, the accuracy of the model was evaluated through the correlation analysis between the estimated rice yield and the yield statistics using the improved model. It was found that the rice yield predicted by the improved model from which the trend was removed showed good agreement with the annual change of yield statistics. Compared with the model before the trend removal, the correlation coefficient and the coefficient of determination were also higher. It was indicated that the trend removal method effectively corrects the rice yield estimation model.

A Study for Fire Examples Involved in Engine Coolant leakage, Brake and Exhaust System Over-Heating of Heavy-Duty Truck Vehicle (대형 트럭 자동차의 엔진냉각수 누출, 제동 및 배기시스템 과열에 관련된 화재사례 고찰)

  • Lee, IL Kwon;Kook, Chang Ho;Ham, Sung Hoon;Lee, Young Suk;Hwang, Han Sub;You, Chang Bae;Moon, Hak Hoon;Jung, Dong Hwa;Ahn, Ho Cheol;Lee, Jeong Ho
    • Journal of the Korean Institute of Gas
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    • v.23 no.4
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    • pp.40-45
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    • 2019
  • This paper is a purpose to study the failure example for heavy-duty vehicle fire. The first example, the researcher found the engine over-heating phenomenon causing a coolant leakage by the sealing poor of head-gasket because of D-ring part deformation contacting with cylinder liner top-part and cylinder head. He certified a fire breakout by short transferred to surrounding wiring of air-cleaner. The second example, a brake lining by return fault of break operating S cam causing with much wear of a rear 4 wheel brake lining repeatably was worn by friction. In the long run, it became the cause of fire. The third example, the researcher knew the fire cause was came about the short of wire by overload of tilting motor when the driver tilted up the cap to inspect a engine. Therefore, a heavy-duty fire must minimize the fire occurrence by thorough controlling.

'Choyoung', Triticale Cultivar for Forage of Early-Heading, Resistance to Lodging and High Seed Production (조숙 내도복 종실 다수성 조사료용 트리티케일 품종 '조영')

  • Han, Ouk-Kyu;Park, Hyung-Ho;Park, Tae-Il;Oh, Young-Jin;Ahn, Jong-Woong;Ku, Ja-Hwan
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.39 no.2
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    • pp.68-74
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    • 2019
  • 'Choyoung', a winter forage triticale cultivar (X Triticosecale Wittmack), was developed at the Department of Rice and Winter Cereal Crop, NICS, RDA in 2015. The cultivar 'Choyoung' has the leaves of medium width, long length and green color and a medium grain of brown color. The heading date of the cultivar 'Choyoung' was April 30 which was 2 days earlier than that of check cultivar 'Shinyoung'. Its tolerance or resistance to cold, wet injury, powdery mildew, and leaf rust was similar to those of the check cultivar. But the resistance to the lodging of cultivar 'Choyoung' was stronger than that of the check. The average forage fresh and dry matter yield of cultivar 'Choyoung' at milk-ripe stages were 40.5 and $15.7MT\;ha^{-1}$, respectively, which were similar to those (40.3 and $16.1MT\;ha^{-1}$) of the check cultivar. The silage quality of 'Choyoung' was higher than that of the check cultivar 'Shinyoung' in crude protein content (5.9%), while was similar to the check cultivar 'Shinyoung' in acid detergent fiber (33.9%), neutral detergent fiber (57.3%), and total digestible nutrients (62.2%). It showed a grain yield of $5.59MT\;ha^{-1}$, which was 38% higher than that of the check cultivar 'Shinyoung' ($4.05MT\;ha^{-1}$). This cultivar is recommended for fall sowing forage crops in areas in which average daily minimum mean temperatures in January are higher than $-10^{\circ}C$.

Synthesis and biological evaluation of diagnostic reagent for prostate cancer using copper-64 radioisotope

  • Ahn, Heesu;Kim, Mi Hyun;Han, Sang Jin;Woo, Sang Keun;Kim, Jung Young;Lee, Kyu Chul;Lim, Il Han;Lee, Yong Jin
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.4 no.2
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    • pp.65-72
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    • 2018
  • Prostate specific membrane antigen (PSMA) is a cell surface membrane protein, which is overexpressed in most prostate cancer. Recently, PET imaging with $[^{68}Ga]$PSMA-HBED-CC has been widely used for the diagnosis of recurrent prostate cancer and the studies on the diagnostic potential of $^{64}Cu$-labeled PSMA ligands reported actively. In this study, we monitored with biological evaluation in vivo and PET imaging of $^{64}Cu$-labeled PSMA ligand ($[^{64}Cu]$PSMA-617). The radiolabelling efficiency and stability of $[^{64}Cu]$PSMA-617 were confirmed by radio-thin layer chromatography. The radiolabeling efficiency of $[^{64}Cu]$PSMA-617 showed over 95%, and stabilities of intact remained over 98% in both human and mouse serum for 48 h. In normal male mice, in vivo uptake of $[^{64}Cu]$PSMA-617 in several organs was measured at 2, 4, 6, 24, 48 h after injection. Rapid blood clearance was observed for $[^{64}Cu]$PSMA-617. The high uptake was observed in the lung, liver, intestines and kidneys at 2 h postinjection, but was low in the other organs (1-2 %ID/g) at 4 h. The dynamic PET/CT images of 22RV1 tumor-bearing nude mice were acquired during 60 min and additionally acquired 24 h and 48 h after injection. In dynamic PET images, $[^{64}Cu]$PSMA-617 uptake ratio in tumors versus muscle was increased as time elaplsed until 60 minutes and remained in tumors at 48 h. In these results, the PET/CT imaging using $[^{64}Cu]$PSMA-617 in prostate cancer is expected to be useful for the diagnosis and treatment of prostate cancer patients.

Factors affecting objective and subjective masticatory ability assessment of Korean elderly people (한국 노인의 객관적·주관적 저작능력 평가에 영향을 미치는 요인)

  • Jung, Hyo-Jung;Min, Yong-Guang;Kim, Hyo-Jung;Lee, Joo-Young;Lee, Eun-Song;Kim, Baek-Il;Ahn, Hyung-Joon
    • Journal of Korean Academy of Oral Health
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    • v.42 no.4
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    • pp.216-223
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    • 2018
  • Objectives: The purpose of the study was to investigate factors affecting the assessment of objective and subjective masticatory ability in the elderly, and to evaluate masticatory ability assessment more accurately. Methods: A total of 112 participants were recruited after oral examination in senior citizen welfare facilities. The participants' masticatory ability was evaluated objectively (Mixing ability index; MAI), and subjectively (Key food intake ability; KFIA). Participants' general characteristics and oral health-related variables were also recorded. Based on masticatory ability assessment, participants were classified as either high or low. IBM SPSS Statistics Ver.23.0 was used for all analyses, including descriptive statistics, Chi-square test, Mann-Whitney U test, Spearman rank correlation, and Logistic regression analysis. Results: Higher masticatory ability was positively correlated with higher scores on MAI and KFIA. Additionally, there was a significant positive correlation between MAI and KFIA. When analyzing factors affecting objective and subjective masticatory ability assessments, Functional tooth units (FTUs) were revealed as a related factor. In subjective masticatory ability assessment, oral moisture, difficulty in chewing, and the Geriatric Oral Health Assessment Index (GOHAI) were also influential factors. Conclusions: In order to accurately assess masticatory ability, it is necessary to use both objective and subjective measures. Additionally, to improve the masticatory ability in the elderly, treatment should be provided to improve overall oral health and satisfaction.

Feasibility Assessment of Spectral Band Adjustment Factor of KOMPSAT-3 for Agriculture Remote Sensing (농업관측을 위한 KOMPSAT-3 위성의 Spectral Band Adjustment Factor 적용성 평가)

  • Ahn, Ho-yong;Kim, Kye-young;Lee, Kyung-do;Park, Chan-won;So, Kyu-ho;Na, Sang-il
    • Korean Journal of Remote Sensing
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    • v.34 no.6_3
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    • pp.1369-1382
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    • 2018
  • As the number of multispectral satellites increases, it is expected that it will be possible to acquire and use images for periodically. However, there is a problem of data discrepancy due to different overpass time, period and spatial resolution. In particular, the difference in band bandwidths became different reflectance even for images taken at the same time and affect uncertainty in the analysis of vegetation activity such as vegetation index. The purpose of this study is to estimate the band adjustment factor according to the difference of bandwidth with other multispectral satellites for the application of KOMPSAT-3 satellite in agriculture field. The Spectral band adjustment factor (SBAF) were calculated using the hyperspectral satellite images acquired in the desert area. As a result of applying SBAF to the main crop area, the vegetation index showed a high agreement rate of relative percentage difference within 3% except for the Hapcheon area where the zenith angle was 25. For the estimation of SBAF, this study used only one set of images, which did not consider season and solar zenith angle of SBAF variation. Therefore, long-term analysis is necessary to solve SBAF uncertainty in the future.