• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.14 no.1
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• pp.86-90
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• 2011

Wilson's disease is an autosomal recessive disorder of copper metabolism consequence of which leads to accumulation of copper in the liver, brain, cornea and other tissues. The manifestations are more likely to be hepatic in the early childhood and neurological in the adolescents. In addition, the abnormalities that develop during disease progression may result in other manifestations such as hematologic, endocrine, or renal findings. We report a thirteen year-old girl who manifested tetany shortly after the initial diagnosis of Wilson's disease. Despite aggressive calcium, magnesium and vitamin D replacement, the hypocalcemia and hypomagnesemia did not respond to the therapy promptly. It took more than three weeks for blood levels of the minerals to be normal. We concluded that tetany occurred in our patient because of hypoparathyroidism as a rare complication of Wilson disease, vitamin D deficiency resulting from various conditions, and inconclusive hypomagnesemia.

• Journal of Korean Society on Water Environment
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• v.22 no.6
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• pp.996-1003
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• 2006

The absorption characteristics of powdered activated carbon doped by transition-metal nanoparticles were investigated to enhance the remove efficiencies of $TCOD_{Mn}$ and Color from the flexo-inks wastewater. According to the adsorption dynamics of PAC and MPAC, the optimal dosage of activated-carbon adsorbents was 3 g/L under the reaction conditions of pH6.0, 30 mill of reaction time, 240 rpm of mixing intensity. The removal efficiencies by the optimal dosages were maximized as 19% $TCOD_{Mn}$, 57% Color for PAC and 88% $TCOD_{Mn}$, 95% Color for MPAC. Freundlich indexes of isotherm absorption were estimated as follows: i) For PAC, k=-8.11, 1/n=2.98, r=0.91 in the raw water, and k=0.14, b/n=0.75, r=0.96 in the biological treatment water, ii) For MPAC, k=2.69, 1/n=0.21, r=0.80 in the raw water, and k=0.74, 1/n=1.17, r=0.95 in the biological treatment water. MPAC (Powdered activated carbon doped by transition-metal nanoaprticles) was very effective in the removal of organics from the raw water and biological treatment water, as Freundlich indexes of 1/n for both types of water were estimated less than 2.0.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2009.04b
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• pp.51-51
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• 2009

Thin Cross 초음파모터의 구조는 그림 1(a)와 같이 크로스형태의 얇은 스테이터에 윗면과 아랫면에 각각 8개의 압전세라믹이 부착된 형태이다. 압전세라믹의 분극방향은 로터와 접촉하는 스테이터의 중심부인 네 개의 타 점에서 순차적인 타원변위가 생성되도록 결정된다. 유한요소해석프로그램인 ATILA 5.2.4를 사용하여 최적설계된 모델을 제작하였고, 푸쉬풀 게이지, x-y 스테이지, rpm 메타, 토크 게이지를 이용하여 구동시스템을 구성하였다. 그림 1(b)는 마이크로컨트롤러(ATmega)를 이용한 구동 드라이버를 보여준다. 한 주기에서 1/4분주의 순차적인 네 개 의 구형파를 생성하고, 이를 push-pull회로를 통하여 90도의 위상차가 나는 정현파를 생성하여 초음파 모터의 구동 전원으로 사용한다. 피드백 회로인 맨코더와 AD 컨버터는 정속도 운전을 위해서 사용되었다. 제안된 구동드라이버를 이용하여 측정한 결과, 기존의 제품화된 드라이버와 비교하여도 특성의 큰 차이를 보이지 않았으며 피드백 회로를 통하여 부하변화에 따른 속도의 극심한 변화를 비교적 안정화 시킬 수 있었다. 입력전압을 증가시킬수록 속도는 선형적인 증가를 보였고 토크는 이와 반대로 감소하는 특성을 보였다. 피드백 제어회로가 없는 경우에는 프리로드 변화에 따른 극심한 속도 변화를 보였고, 피드백 제어를 하였을 경우에는 0.2~0.4[N]의 범위에서 정속도 운전이 가능함을 확인하였으며, 장시간의 운전에도 온도 및 속도특성이 안정적인 특성을 보였다.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.29 no.10
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• pp.601-607
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• 2016

Piezoelectric thick films of soft $Pb(Zr,Ti)O_3$ (PZT) based commercial material (S55) were fabricated using a conventional tape casting method. Ag-Pd electrodes were printed on the piezoelectric film at room temperature and all 5 layered films with a dimension of $12mm{\times}16mm$ were successfully laminated for a multi-layered piezoelectric ceramic actuator. The laminated specimens were co-fired at $1,100^{\circ}C$ for 1 h. A flat layered and dense microstructure was obtained for the $112{\mu}m$ thick piezoelectric actuator after sintering process. Thereafter, a prototype piezoelectric speaker was fabricated using the multi-layered piezoelectric ceramic actuator which can operate as a bimorph. Its SPL (sound pressure level) characteristic was also evaluated for speaker application. Frequency response revealed that the output SPL with a root mean square voltage of 10 V increased gradually to the highest peak of 87.5 dB for 1.5 kHz and exhibited a relatively stable behavior over the measured frequency range (${\leq}20kHz$) at a distance of 10 cm, implying that the fabricated piezoelectric speaker is potential for speaker applications.

• Genomics & Informatics
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• v.8 no.1
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• pp.50-57
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• 2010

Mercuric chloride, a model nephrotoxicant was used to elucidate time- and dose- dependent global gene expression changes associated with proximal tubular toxicity. Rat kidney cell lines NRK-52E cells were exposed for 2, 6 and 12 hours and with 3 different doses of mercuric chloride. Cell viability assay showed that mercuric chloride had toxic effects on NRK-52E cells causing 20% cell death (IC20) at $40{\mu}M$ concentration. We set this IC20 as high dose concentration and 1/5 and 1/25 concentration of LC20 were used as mid and low concentration, respectively. Analyses of microarray data revealed that 738 genes were differentially expressed (more than two-fold change and p<0.05) by low concentration of mercuric chloride at least one time point in NRK-52E cells. 317 and 2,499 genes were differentially expressed at mid and high concentration of mercuric chloride, respectively. These deregulated genes showed a primary involvement with protein trafficking (CAV2, CANX, CORO1B), detoxification (GSTs) and immunity and defense (HMOX1, NQO1). Several of these genes were previously reported to be up-regulated in proximal tubule cells treated with nephrotoxicants and might be aid in promoting the predictive biomarkers for nephrotoxicity.

• Journal of Yeungnam Medical Science
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• v.29 no.1
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• pp.48-53
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• 2012

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths in South Korea. To decrease its mortality rate, its early detection is very important. Screening for HCC detection has been accepted as the management modality for patients with chronic liver disease. Reported herein is a case involving the marked rapid growth of HCC detected at an advanced stage in a screening test with a 3 months interval. A 49-year-old male patient with chronic hepatitis B was admitted to the hospital due to a liver mass detected on CT scan. The patient underwent a first CT scan 3 months earlier, and no tumor was detected. Follow-up CT scan was performed and showed a 9.1 cm HCC with portal vein thrombosis. Percutaneous liver biopsy was performed, and the diagnosis of hepatocellular carcinoma was confirmed. In the pertinent guidelines, the recommended screening interval for HCC is 6-12 months, but the screening interval and additional diagnostic methods should be considered due to the variation in the HCC growth rate according to the patient's clinical characteristics.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.28 no.3
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• pp.316-324
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• 1995

Ecology and life History of the mudskipper, Boieophthaimus pectinirostris were investigated based on the specimens collected from the Korean roasts from 1978 to 1994. The spawning of this species takes place during the period from June to August. Prolarva hatched from egg was 3.3mm in total length, and began to bottom life in TL 16.0mm of 40 days after hatching. The stomach contents were principally diatoms. In the foraging behavior, this species were conducted at the wet soft mud on the upper tidal zones. The burrowing observed in the intertidal mud flat was YL type. B. pectinirostris is restricted to western and southwestern coast of Korea, but their habitats and individuals are being reduced by the result of reclimation to tide land.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2005.04a
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• pp.35-38
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• 2005

In our country, the skin image and MR Microscopy research has been processed but there were not their outstanding results. So this study start to improve the techniques can get high resolution skin images and to make RF surface coils. Volume coils are sometimes unavailable, or do not provide adequate RF power or SNR for some applications. In high resolution skin and tissue structure images current coils have a technical limitation. It is well known that standard single-loop surface coils, although offering high SNR characteristics, have poor B1 homogeneity. As the RF surface coil need change its geometry we get improved images. So, The magnetic field simulation that is first step to make and design RF surface coil will support reference data.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.11B
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• pp.1289-1295
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• 2009

Premature ventricular contractions are the most common of all arrhythmias and may cause more serious situation like ventricular fibrillation and ventricular tachycardia in some patients. Therefore, the detection of this arrhythmia becomes crucial in the early diagnosis and prevention of possible life threatening cardiac diseases. Particularly, in the healthcare system that must continuously monitor people's situation, it is necessary to process ECG signal in realtime. In other words, design of algorithm that exactly detects R wave using minimal computation and classifies PVC is needed. So, R wave detection algorithm based adaptive threshold and window for the classification of PVC is presented in this paper. For this purpose, ECG signals are first processed by the usual preprocessing method and R wave was detected and adaptive window through R-R interval is used for efficiency of the detection. The performance of R wave detection and PVC classification is evaluated by using MIT-BIH arrhythmia database. The achieved scores indicate 99.33%, 88.86% accuracy respectively for R wave detection and PVC classification.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.10B
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• pp.919-928
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• 2006

A periodic broadcasting is known as an efficient technique for delivering popular videos to reduce bandwidth requirements for transmitting streaming video to viewers in video-on-demand (VoD) services. However, the most periodic VoD schemes approach needs frequency channel hopping, many segments of video managing, and using many channel at the same time. These make it difficult to implement. In this paper, we propose a Staircase Staggered broadcasting scheme which has a simple structure and substantially improved VoD efficiency. The numerical results demonstrate that the viewer's waiting time of the Staircase Staggered broadcasting scheme is close to the staircase broadcasting scheme and the maximum buffer requirements of this can be adapted for demanding rate by adjusting the short front part of a video sizes.