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A Case of Fasciola hepatica Infection Mimicking Cholangiocarcinoma and ITS-1 Sequencing of the Worm

  • Kang, Bong Kyun;Jung, Bong-Kwang;Lee, Yoon Suk;Hwang, In Kyeom;Lim, Hyemi;Cho, Jaeeun;Hwang, Jin-Hyeok;Chai, Jong-Yil
    • Parasites, Hosts and Diseases
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    • v.52 no.2
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    • pp.193-196
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    • 2014
  • Fascioliasis is a zoonotic infection caused by Fasciola hepatica or Fasciola gigantica. We report an 87-year-old Korean male patient with postprandial abdominal pain and discomfort due to F. hepatica infection who was diagnosed and managed by endoscopic retrograde cholangiopancreatography (ERCP) with extraction of 2 worms. At his first visit to the hospital, a gallbladder stone was suspected. CT and magnetic retrograde cholangiopancreatography (MRCP) showed an intraductal mass in the common bile duct (CBD) without proximal duct dilatation. Based on radiological findings, the presumed diagnosis was intraductal cholangiocarcinoma. However, in ERCP which was performed for biliary decompression and tissue diagnosis, movable materials were detected in the CBD. Using a basket, 2 living leaf-like parasites were removed. The worms were morphologically compatible with F. hepatica. To rule out the possibility of the worms to be another morphologically close species, in particular F. gigantica, 1 specimen was processed for genetic analysis of its ITS-1 region. The results showed that the present worms were genetically identical (100%) with F. hepatica but different from F. gigantica.

A Method to Evaluate Distance Efficiency of Seoul Metropolitan Subway by Estimating Subway Detour Factor (지하철 우회계수 산정을 통한 수도권 지하철의 거리 효율 평가 모형)

  • LEE, Jae Min;KIM, Nam Seok
    • Journal of Korean Society of Transportation
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    • v.33 no.3
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    • pp.304-314
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    • 2015
  • Detour of metro (subway) in metropolitan area has been regarded as one of inherent elements that make entire metro system less competitive than passenger cars. However, factors affecting detour of metro line is not specified clearly when a new subway system is planned or an existing system is improved. Previous detour-related studies was reviewed for developing 'distance efficeincy evaluation model' for metro as well as its counterpart (i.e. road). Metro line 3 (orange line) of Seoul metropolitan area was applied as a case study. As a results, the most detoured OD segment is Daechi - Apgujeong and its detour factor is 1.93 which means that the distance of the metro is 1.93 times longer distance compared to the distance of the road. The metro line 3 has averagely 20% longer distance compared to road for the identical O/D pairs.

Rectangular Waveguide-NRD Waveguide Transition having the NRD Waveguide Built-in Structure (NRD 도파관에 내장된 구조를 갖는 구형 도파관-NRD 도파관 트랜지션)

  • Yoo, Young-Geun;Choi, Jae-Ha
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.19 no.4
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    • pp.391-396
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    • 2008
  • In this paper, we proposed the new rectangular waveguide-NRD waveguide transition in which the transition function about the standard waveguide is built in within the NRD waveguide ifself. The newly proposed rectangular waveguide-NRD waveguide transition was realized use of NRD waveguide input/output side wall thickness and hole width. In the case of the wall thickness, it was nearly identical with the half of the NRD waveguide guide wavelength and the width of an hole was nearly coincide with the length of the long side of the standard waveguide connected with the NRD waveguide. This kind of the principles is applicable to be unrelated with the frequency band. In this paper, it made in 38 GHz band with the rectangular waveguide-NRD waveguide transition and the feasibility was confirmed. In the back-to-back structure, the rectangular waveguide-NRD waveguide transition manufactured in 38 GHz band has the insertion loss less than 0.4 dB and also has the return loss less than 20 dB.

A Study on Wear and Wear Mechanism of Exhaust Valve and Seat Insert Depending on Different Speeds Using a Simulator

  • Hong, Jae-Soo;Chun, Keyoung-Jin;Youn, Young-Han
    • Journal of Mechanical Science and Technology
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    • v.20 no.12
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    • pp.2052-2060
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    • 2006
  • The wear of engine valve and seat insert is one of the most important factors which affect engine performance. Because of higher demands on performance and the increasing use of alternative fuel, engine valve and seat insert are challenged with greater wear problems than in the past. In order to solve the above problems, a simulator was developed to be able to generate and control high temperatures and various speeds during motion. The wear simulator is considered to be a valid simulation of the engine valve and seat insert wear process with various speeds during engine activity. This work focuses on the different degrees of wear at three different singular test speeds (10 Hz, 25 Hz & multi-Hz). For this study, the temperature of the outer surface of the seat insert was controlled at 350$^{\circ}C$, and the test load was 1960 N. The test cycle number was $6.0{\times}10^6$. The mean ($\pm$standard error) wear depth of the valve at 10 Hz and 25 Hz was 45.1 ($\pm$3.7)$\mu$m and 81.7 ($\pm$2.5)$\mu$m, respectively. The mean wear depth of the seat insert at 10 Hz and 25 Hz was 52.7 ($\pm$3.9)$\mu$m and 91.2 ($\pm$2.7)$\mu$m, respectively. In the case of multi-Hz it was 70.7 ($\pm$2.4)$\mu$m and 77.4 ($\pm$3.8)$\mu$m, respectively. It was found that higher speed (25 Hz) cause a greater degree of wear than lower speed (10 Hz) under identical test condition (temperature, valve displacement, cycle number and test load). In the wear mechanisms of valves, adhesive wear, shear strain and abrasive wear could be observed. Also, in the wear mechanisms of seat inserts, adhesive wear, surface fatigue wear and abrasive wear could be observed.

A Legal Review on Physical Therapists' Roles and Doctors' Superintendency (물리치료사의 업무범위와 의사의 지도권에 관한 법적 검토 - 청주지방법원 2010. 2. 3. 선고 2009노1317 판결 -)

  • Kim, Han-Nah;Kim, Kye-Hyun
    • The Korean Society of Law and Medicine
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    • v.11 no.2
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    • pp.337-361
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    • 2010
  • In the case of Korea, both of modern medicine and oriental medicine are admitted as medical practices in the system. In other words, healthcare system is dualized. However, medical practice that corresponds to oriental medicine in Korea is substitution of medical practice in cases of foreign countries. For use of medical devices, it is provided only for doctors and medical technician relevant to use. Particularly, although oriental medicine is recognized as orthodox medicine in terms of the features of Korean medical system, superintendency of oriental doctors is not identical with that of doctors for use of medical devices and superintendency toward medical technicians. Recently, Cheongju District Court decided that superintendency of oriental doctor upon physical therapist is not acknowledged. It can be said that the judgement is opposed to the original verdict which judged that oriental doctors' employment and guidance of oriental doctors upon physical therapist is permissible. Hence this study aimed to review on domestic medical law system, which is dualized, roles of medical professionals, intent of the medical license system, provisions related to medical technician law and relevant precedents. Regulations on practices other than licensed practices by medical professionals are made because medical practices may affect on danger toward life and body of human and public health also. Therefore, the nation regulates medical professionals having licenses to perform medical practices within the range of the licenses. It is clearly prescribed that medical technicians may perform medical practices under instructions of doctors or dentists pursuant to the medical technician law. In addition, the court also judges that it is out of the license of oriental doctors if they use CT devices and limits the use of modern medical devices by oriental doctors. That is to say that it limits oriental doctors' employment of medical technicians and pursuant of oriental doctors on medical technicians as well.

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ALLOCATION AND PRICING IN PUBLIC TRANSPORTATION AND THE FREE RIDER THEOREM

  • Beckmann, Martin J.
    • Journal of the Korean Operations Research and Management Science Society
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    • v.3 no.1
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    • pp.31-46
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    • 1978
  • Consider a time interval during which the demand for trips is fixed (e.g. the rush hour period). The traveller has a choice between various public modes, whose travel times and fares are fixed, and the automobile mode, for which travel time and cost depend on the volume of traffic flow on those roads, which are subject to congestion. We consider the equilibrium in terms of a representative travellerm, who choses for any trip the mode and route with the least combined money and time cost. When several (parallel) model or routes are chosen, then the combined cost of money and time must be equal among these. Our problem is first, to find the optimal flows of cars and of public mode carriers on the various links of their networks and second the optimal fares for trips by the variousmodes. The object is to minimize the total operating costs of the carriers and car plus the total time costs to travellers. The optimal fares are related to, but not identical with the dual variables of the underlying Nonlinear Program. They are equal to these dual variables only in the case, when congestion tolls on trips or on the use of specific roads are collected from automobile users. When such tolls are not collected, they must be passed on as subsidies to travellers using competing modes. The optimal fares of public modes are then reduced by the amounts of these subsidies. Note that subsidies are not a flat payment to public carriers, but are calculated on the basis of tickets sold. Fares and subsidies depend in general on tile period considered. They will be higher during periods of higher demand. When the assumption of fixed trip demand is relaxed, this tare system is no longer best, but only second best since too much traffic will, in general, be generated. The Free Rider Theorem states the following : Suppose road tolls can be charged, so that a best pricing system for public modes is posssible. Then there may exist free rides on some routes and modes, but never on a complete round trip.

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A Study on Non-Subtraction and Subtraction Technique in 3-Dimensional Angiography of the Cerebral Aneurysm (뇌동맥자루 3차원 혈관조영술에서 비감산 및 감산 기법에 관한 연구)

  • Kim, Kyung-Wan;Im, In-Chul;Lee, Hyo-Yeong
    • Journal of the Korean Society of Radiology
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    • v.12 no.4
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    • pp.511-518
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    • 2018
  • The purpose of this study was to measured the diameter, maximum diameter, maximum area and volume of the cerebral aneurysm in 53 patients who underwent three-dimensional digital angiography and three-dimensional digital subtraction angiography, which were used for the clinical diagnosis of cerebral aneurysm, image noise and radiation exposure dose of each test method were analyzed to compare clinical diagnosis differences in the cerebral aneurysm diagnosis. Three-dimensional digital angiography and three-dimensional digital subtraction angiography showed that the neck diameter, maximum diameter, maximum area, volume, and noise of the cerebral aneurysm were identical or very small. However, the three-dimensional digital angiography significantly decreased the radiation exposure dose compared to three-dimensional digital subtraction angiography. Therefore, in case of clinical diagnosis of cerebral aneurysm, three-dimensional digital angiography should be preferentially used to reduce radiation exposure dose of patient.

Identification of Genes for Growth with Oxygen in Escherichia coli by Operon Fusion and Southern Blot Techniques

  • Kim, Il-Man;Lee, Yong-Chan;Won, Jae-Seon;Choe, Mu-Hyeon
    • Journal of Microbiology and Biotechnology
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    • v.13 no.6
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    • pp.976-983
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    • 2003
  • Seven Escherichia coli cells defective with aerobic growth were isolated by the insertion of ${\lambda}placMu53$, a hybrid bacteriophage of ${\lambda}$ and Mu, which created a transcriptional fusion to lacZY. These insertion mutant cells were tested on an XG ($5-bromo-4-chloro-3-indolyl-{\beta}-D-galactopyranoside$) medium for anaerobic expression of lacZ by fusion to a promoter. The chromosomal DNA from these strains were digested by EcoRI, and the EcoRI fragments that contained the fused gene and lacZ sequence were identified by Southern hybridization, using lacZ containing plasmid as a probe. The EcoRI fragment from each strain was cloned and sequenced. The sequence data were compared with the GenBank database. The mutated gene of three strains, CYT4, CYT5, and OS11, was found to be identical, and it was nrdAB that encoded ribonucleoside diphosphate reductase. The gene nrdAB was at min 50.5 on the Escherichia coli linkage map and 2,348,084 on the physical map, and is involved in hemAe-related reduction-oxidation reaction. OS6 and OS14 mutant strains had insertion at min 8.3 and the mutated gene was hemB. The hemB encodes 5-aminolevulinate dehydratase or porphobilinogen synthase. The OS3 mutant had insertion in cydB at min 16.6. The cydAB encodes cytochrome d oxidase. In the case of OS1, the fusion was made with sucA, the E1 component of ${\alpha}-ketoglutarate$ dehydrogenase.

Structural Behavior of Sandwich Type GFRP Arch and Field Applicability (샌드위치형 GFRP 아치의 구조적 거동 및 현장 적용성)

  • Hwang, Dae-Won;Kim, Kwang-Woo;Kim, Yong-Seong;Yeon, Kyu-Seok
    • Journal of The Korean Society of Agricultural Engineers
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    • v.60 no.2
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    • pp.85-93
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    • 2018
  • This study investigated the structural behavior and field applicability of sandwich type GFRP arches with polymer mortar in core. As a result, in case of crack loading and failure loading, total strains at crown were the highest; the fracture strain at crown was 0.01690, which is 4.2 times greater than the fracture strain (0.004) of cement concrete. The 3 % deflection load was 17.42 kN, the flexural strength was $163.98{\times}10^{-3}GPa$, and the flexural elastic modulus was 11.884 GPa. From load-deflection relationship up to 3.5 % deflection, 3D analysis results and experimental values were observed to be almost identical. It was considered reasonable to set a deflection rate limit to be 3 % for structural safety purpose. The standard external flexural strength of semicircular arch used in this study was approximately 2.64 times higher than that of hume pipe (2 type standard) and tripled composite pipe. The external pressure strength at fracture was approximately 1.57 times higher than that of hume pipe. It was confirmed that the implementing semicircular arch had mechanically more advantage than the circular pipe. Optimum member thickness was 8~53 mm according to arch radius of 450~1,800 mm and cover depth of 2~10 m. It was found that the larger strength could be obtained even if the thickness of member was smaller than that of concrete structure. In field application study, figures and equations were derived for obtaining applicable cover depth and optimum member thickness according to loading conditions. These would be useful data for design and manufacture of sandwich type semicircular arch.

Analysis and Evaluation of Term Suggestion Services of Korean Search Portals: The Case of Naver and Google Korea (검색 포털들의 검색어 추천 서비스 분석 평가: 네이버와 구글의 연관 검색어 서비스를 중심으로)

  • Park, Soyeon
    • Journal of the Korean Society for information Management
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    • v.30 no.2
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    • pp.297-315
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    • 2013
  • This study aims to analyze and evaluate term suggestion services of major search portals, Naver and Google Korea. In particular, this study evaluated relevance and currency of related search terms provided, and analyzed characteristics such as number and distribution of terms, and queries that did not produce terms. This study also analyzed types of terms in terms of the relationship between queries and terms, and investigated types and characteristics of harmful terms and terms with grammatical errors. Finally, Korean queries and English queries, and popular queries and academic queries were compared in terms of the amount and relevance of search terms provided. The results of this study show that the relevance and currency of Naver's related search terms are somewhat higher than those of Google. Both Naver and Google tend to add terms to or delete terms from original queries, and provide identical search terms or synonym terms rather than providing entirely new search terms. The results of this study can be implemented to the portal's effective development of term suggestion services.