• Title/Summary/Keyword: IVL

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Identification of Antioxidant Activities and Stimulation of Human Keratinocytes Differentiation Effects of Syzygium claviflorum Extract (Syzygium claviflorum 추출물의 항산화 활성 및 각질형성세포 분화유도 효과)

  • Gayeon Seo;Jiyeon Moon;Yukyung Park;Juyeong Kim;Hoyong Hyun;Beomsu Jeong;Thet Thet Mar Win;Thant Zaw Win;Sangho Choi;Sangmi Eum;Dongwon Kim
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.49 no.1
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    • pp.59-65
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    • 2023
  • We validated the physiological activity of Syzygium claviflorum (Roxb.) Wall. ex A.M. Cowan & Cowan (S. claviflorum) extracts (leaves, stems, fruits, and flowers) as a cosmetic ingredient. Firstly, S. claviflorum extracts removed over 80% of free radicals at various concentrations in antioxidant experiments using the DPPH and ABTS assay. In cytotoxicity experiments using human epidermal keratinocytes, S. claviflorum extracts showed low cytotoxicity. In addition, S. claviflorum extracts significantly increased the expression of keratin (KRT)1, KRT2, KRT9, KRT10, which are differentiation markers of keratinocytes, as well as genes involved in the maintenance of skin barrier function, including involucrin (IVL), loricrin (LOR), filaggrin (FLG), and claudin1 (CLDN1). In particular, the expression of FLG protein, inhibited by interleukin (IL)-4/IL-13 in atopic dermatitis, was restored by S. claviflorum extracts in in vitro experiments. Therefore, S. claviflorum extracts with excellent antioxidant efficacy and skin barrier improvement function will be useful materials for the development of future atopic dermatitis treatments and cosmetics.

Study on optimal elctrode's thickness at passive OLED on power consumption

  • Kim, Sang-Gil;Park, Sung-Joon;Kim, Jeong-Hoon;Song, Keun-Joo;Kim, Hee-Je
    • Proceedings of the KIEE Conference
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    • 2004.07c
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    • pp.1945-1947
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    • 2004
  • "CRT" which had dominated the market of display until 2000 is not appropriate for information indicating media due to several limitations. Thus, TFT-LCD, PDP, OLED, etc are growing in display industry instead of CRT because they meet demands of information indicating media. OLED display which responses within 1ms fits any picture manifestation medias because it uses self radiance OLED for picture clement that has no obstacles in showing the angle of vision. OLED's characteristic of action is very sensitive to thickness of electrode so that this has been an important issue. This study tried to find the most suitable thickness of electrode using ITO, Mo, and AL. Using the results of IVL measurements, analyzed equality of electrode board. As a result, found the thickness of electrode that has high electrical efficiency and optimized it.

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effect of Pasture ages on the Dry Matter Yield , Botanical Composition and Forage Quality of Pasture Mixtures (초지경년이 건물수량 , 식생비율 및 사료가치에 미치는 영향)

  • 한인규;김동암;조무환;이필상
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.14 no.4
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    • pp.264-270
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    • 1994
  • This experiment was undertaken to determine the effect of pasture ages on the total production and seasonal yield trends, botanical composition and forage quality of pasture mixtures. This experiment was conducted at the Livestock Experiment Station, RDA, Suweon. The results obtained were as follows : 1. Total dry matterDM) yield of pasture mixtures was the highest in the first year, and thereafter no significant reduction in the 2nd through the 4th year, but decreased by 30% in the 5th year. 2. The 34.4% of total DM yield was produced at the first cut, and decreased from then on. Total DM yield of pasture mixtures varied by year and climatic facton. In 1992, Total DM and TDN yields of pasture mixtures were 13.4 and 8.5 IvlT/ha, respectively. 3. The content of crude protein(CP), in virro DM digestibility(IVDMD) and TDN of pasture mixtures were 12-14, 70-80, and 62-65%, respectively. The highest forage quality was obtained at the 4th cutting. 4. The botanical compositions of legumes and weeds were increased as the year of establishment advanced, and highly increased at the 3rd cut after summer growth. 5. Based on the results of this study it appears that economic forage production could be expended to the 4th year with proper management, and the special renovation techniques may be needed for maintenance of pasture yield from the 5th year.

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Construction of the remote monitoring system for MX-13 digital multiplexer (광회선 다중화장치 원격감시시스템 구축)

  • Jang, Moon-Jong;Park, Byung-Seok;Ahn, Seong-Joon;Woo, Hee-Gon
    • Proceedings of the KIEE Conference
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    • 1999.07g
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    • pp.2947-2949
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    • 1999
  • The MX-13 digital multiplexer for leased line is one of the main facilities, so it is periodically monitored by the operator. Operators connect dummy terminal to the MX-13 digital multiplexer manually, and execute preventing inspection. When alarms occurred, they are manually checked by the operator. But, in order to get mere efficiency of accident prevention and monitoring facilities with rapid response to the accident symptom, and to get higher reliability from the companies who lease communication lines, we need to construct this system which is adequate to monitor IvlX-13 digital multiplexer in almost real time. We construct remote monitoring system for MX-13 digital multiplxer to meet those requirement. After constructing the system, it's possible that the local operator can manage local monitoring system to check the status of MX-13 digital multiplexers. Also, Center operator can monitor the facility which has problems, and located in the specific local areas with the use of Center monitoring system.

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In Vitro Anti-Inflammatory and Skin Protective Effects of Codium fragile Extract on Macrophages and Human Keratinocytes in Atopic Dermatitis

  • A-yeong Jang;JeongUn Choi;Weerawan Rod-in;Ki Young Choi;Dae-Hee Lee;Woo Jung Park
    • Journal of Microbiology and Biotechnology
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    • v.34 no.4
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    • pp.940-948
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    • 2024
  • Codium fragile has been traditionally used in oriental medicine to treat enterobiasis, dropsy, and dysuria, and it has been shown to possess many biological properties. Atopic dermatitis (AD) is one of the types of skin inflammation and barrier disruption, which leads to chronic inflammatory skin diseases. In the current investigation, the protective effects of C. fragile extract (CFE) on anti-inflammation and skin barrier improvement were investigated. In LPS-stimulated RAW 264.7 cells, nitric oxide generation and the expression levels of interleukin (IL)-1β, IL-4, IL-6, iNOS, COX-2, and tumor necrosis factor-alpha (TNF)-α were reduced by CFE. CFE also inhibited the phosphorylation of NF-κB-p65, ERK, p-38, and JNK. Additionally, CFE showed inhibitory activity on TSLP and IL-4 expression in HaCaT cells stimulated with TNF-α/interferon- gamma (IFN-γ). Enhanced expression of factors related to skin barrier function, FLG, IVL, and LOR, was confirmed. These findings implied that CFE may be used as a therapeutic agent against AD due to its skin barrier-strengthening and anti-inflammatory activities, which are derived from natural marine products.

EFFECT OF VALVE TIMING AND LIFT ON FLOW AND MIXING CHARACTERISTICS OF A CAI ENGINE

  • Kim, J.N.;Kim, H.Y.;Yoon, S.S.;Sa, S.D.;Kim, W.T.
    • International Journal of Automotive Technology
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    • v.8 no.6
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    • pp.687-696
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    • 2007
  • To increase the reliability of auto-ignition in CAI engines, the thermodynamic properties of intake flow is often controlled using recycled exhaust gases, called internal EGR. Because of the internal EGR influence on the overall thermodynamic properties and mixing quality of the gases that affect the subsequent combustion behavior, optimizing the intake and exhaust valve timing for the EGR is important to achieve the reliable auto-ignition and high thermal efficiency. In the present study, fully 3D numerical simulations were carried out to predict the mixing characteristics and flow field inside the cylinder as a function of valve timing. The 3D unsteady Eulerian-Lagrangian two-phase model was used to account for the interaction between the intake air and remaining internal EGR during the under-lap operation while varying three major parameters: the intake valve(IV) and exhaust valve(EV) timings and intake valve lift(IVL). Computational results showed that the largest EVC retardation, as in A6, yielded the optimal mixing of both EGR and fuel. The IV timing had little effect on the mixing quality. However, the IV timing variation caused backflow from the cylinder to the intake port. With respect to reduction of heat loss due to backflow, the case in B6 was considered to present the optimal operating condition. With the variation of the intake valve lift, the A1 case yielded the minimum amount of backflow. The best mixing was delivered when the lift height was at a minimum of 2 mm.