• Title/Summary/Keyword: ISR

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Impact of Interatrial Septal Reconstruction on Atrial Tachyarrhythmia after Surgical Resection of Myxoma

  • Mi Young Jang;Jun Ho Lee;Muhyung Heo;Suk Kyung Lim;Su Ryeun Chung;Kiick Sung;Wook Sung Kim;Yang Hyun Cho
    • Journal of Chest Surgery
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    • v.56 no.3
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    • pp.186-193
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    • 2023
  • Background: Complete surgical excision is the only curative treatment for primary cardiac tumors. For wide excision, interatrial septal reconstruction (ISR) is commonly performed. We hypothesized that ISR may increase the risk of postoperative atrial tachyarrhythmia (AT) after surgical resection of cardiac myxoma. Methods: After excluding patients with a history of cardiac surgery and concomitant procedures unrelated to tumor resection and those with AT or permanent pacemakers, we finally enrolled 272 adult patients who underwent benign cardiac tumor surgery from 1995 to 2021 at our institution. They were divided into the ISR (n=184) and non-ISR (n=88) groups. The primary outcome was postoperative new-onset AT. Results: The study cohort predominantly consisted of women (66.2%), with a mean age of 57.2±13.6 years. The incidence of postoperative new-onset AT was 15.4%. No 30-day mortality or recurrence was observed. The cardiopulmonary bypass time and aortic cross-clamping time were significantly longer in the ISR group than in the non-ISR group (p<0.001). The median duration of hospital stay of all patients was 6.0 days (interquartile range, 5.0-7.0 days), and no significant difference was observed between the 2 groups (p=0.329). ISR was not an independent predictor of new-onset AT (p=0.248). Male sex and hypertension were found to be independent predictors of new-onset AT. Conclusion: ISR was not a significant predictor of postoperative new-onset AT. ISR might be a feasible and safe procedure for surgical resection of cardiac myxoma and should be considered if needed.

Civilian Application of the C4ISR Architecture Design Methodology (C4ISR 구조설계 방법론의 민간부문 적용방안;체계통합 관점을 중심으로)

  • Jeon, Byung-Wook
    • 한국IT서비스학회:학술대회논문집
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    • 2002.06a
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    • pp.376-380
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    • 2002
  • 본고에서는 국방 정보체계구축시 표준준수 및 체계통합을 이룩하여 효율적인 합동전력의 운용이 가능한 C4ISR체계의 구조설계방법과 상호운용성을 구현하기 위한 전략을 소개하고자 한다. 이와 함께 국방정보체계 구축시 적용되는 C4ISR 구조설계방법을 Zachman 구조설계방법과 대비하여 향후에 민간부문에서 활용할 수 있는 방안을 고찰하고자 한다.

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Use of 16S-23S rRNA Intergenic Spacer Region for Species-specific Primer Developed of Vibrio Ichthyoenteri (16S-23S rRNA Intergenic Spacer Region을 이용한 Vibrio ichthyoenteri Species-specific Primer 개발)

  • Moon Young-Gun;Heo Moon-Soo
    • Korean Journal of Microbiology
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    • v.41 no.2
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    • pp.117-124
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    • 2005
  • Two bacterial isolates obtained from rotifer and diseased olive flounder larvae, Paralichthys olivaceus, were identified as Vibrio ichthyoenteri based on the results of phenotypic characterization. In an attempt to develop rapid PCR method for the detection of V. ichthyoenteri, we examined the 16S-23S rRNA intergenic spacer region(ISR) of V. ichthyoenteri and developed species-specific primer for V. ichthyoenteri. Analysis of the ISR sequences showed that V. ichthyoenteri contains one type of polymorphic ISRs. The size of ISRs was 348 bp length and did not contain tRNA genes. Mutiple alignment of representative sequences from different V. species revealed several domains of high sequence variability, and allowed to design species-specific primer for detection of V. ichthyoenteri. The specificity of the primer was examined using genomic DNA prepared from 19 different V. species, isolated 18group Vibrio species and most similar sequence of other known Vibrio species. The results showed that the PCR reaction using species-specific primer designed in this study can be used to detect V. ichthyoenteri.

Hybrid Feature Selection Method Based on a Naïve Bayes Algorithm that Enhances the Learning Speed while Maintaining a Similar Error Rate in Cyber ISR

  • Shin, GyeongIl;Yooun, Hosang;Shin, DongIl;Shin, DongKyoo
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.12 no.12
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    • pp.5685-5700
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    • 2018
  • Cyber intelligence, surveillance, and reconnaissance (ISR) has become more important than traditional military ISR. An agent used in cyber ISR resides in an enemy's networks and continually collects valuable information. Thus, this agent should be able to determine what is, and is not, useful in a short amount of time. Moreover, the agent should maintain a classification rate that is high enough to select useful data from the enemy's network. Traditional feature selection algorithms cannot comply with these requirements. Consequently, in this paper, we propose an effective hybrid feature selection method derived from the filter and wrapper methods. We illustrate the design of the proposed model and the experimental results of the performance comparison between the proposed model and the existing model.

Priming of Defense-Related Genes Confers Root-Colonizing Bacilli-Elicited Induced Systemic Resistance in Pepper

  • Yang, Jung-Wook;Yu, Seung-Hun;Ryu, Choong-Min
    • The Plant Pathology Journal
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    • v.25 no.4
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    • pp.389-399
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    • 2009
  • A group of beneficial plant bacteria has been shown to increase crop growth referring to as plant growth-promoting rhizobacteria (PGPR). PGPR can decrease plant disease directly, through the production of antagonistic compounds, and indirectly, through the elicitation of a plant defense response termed induced systemic resistance (ISR). While the mechanism of PGPR-elicited ISR has been studied extensively in the model plant Arabidopsis, it is less well characterized in crop plants such as pepper. In an effort to better understand the mechanism of ISR in crop plants, we investigated the induction of ISR by Bacillus cereus strain BS107 against Xanthomonas axonopodis pv. vesicatoria in pepper leaves. We focused on the priming effect of B. cereus strain BS107 on plant defense genes as an ISR mechanism. Of ten known pepper defense genes that were previously reported to be involved in pathogen defense signaling, the expression of Capsicum annum pathogenesis-protein 4 and CaPR1 was systemically primed by the application of strain BS107 onto pepper roots confirming by quantitative-reverse transcriptase PCR. Our results provide novel genetic evidence of the priming effect of a rhizobacterium on the expression of pepper defense genes involved in ISR.

Identification of an ISR-Related Metabolite Produced by Pseudomonas chlororaphis O6 against the Wildfire Pathogen Pseudomonas syringae pv. tabaci in Tobacco

  • Park, Myung-Ryeol;Kim, Young-Cheol;Park, Ju-Yeon;Han, Song-Hee;Kim, Kil-Yong;Lee, Sun-Woo;Kim, In-Seon
    • Journal of Microbiology and Biotechnology
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    • v.18 no.10
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    • pp.1659-1662
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    • 2008
  • Pseudomonas chlororaphis O6 exhibits induced systemic resistance (ISR) against P. syringae pv. tabaci in tobacco. To identify one of the ISR metabolites, O6 cultures were extracted with organic solvents, and the organic extracts were subjected to column chromatography followed by spectroscopy analyses. The ISR bioassay-guided fractionation was carried out for isolation of the metabolite. High-resolution mass spectrometric analysis of the metabolite found $C_{9}H_{9}O_{3}N$ with an exact mass of 179.0582. LC/MS analysis in positive mode showed an $(M+H)^{+}$ peak at m/z 180. Nuclear magnetic resonance ($^{1}H,\;^{13}C$) analyses identified all protons and carbons of the metabolite. Based on the spectroscopy data, the metabolite was identified as 4-(aminocarbonyl) phenylacetate (4-ACPA). 4-ACPA applied at 68.0 mM exhibited ISR activity at a level similar to 1.0 mM salicylic acid. This is the first report to identify an ISR metabolite produced by P. chlororaphis O6 against the wildfire pathogen P. syringae pv. tabaci in tobacco.

Design of SAR Satellite Constellation Configuration for ISR Mission (ISR 임무를 위한 SAR 위성의 군집궤도 배치형상 설계)

  • Kim, Hongrae;Song, Sua;Chang, Young-Keun
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.45 no.1
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    • pp.54-62
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    • 2017
  • For the Earth observation satellite for ISR mission, a satellite constellation can be utilized to observe a specific area periodically and ultimately increase the effectiveness of the mission. The Walker-Delta method was applied to design constellation orbits with four satellites, which could detect abnormal activities in AoI(Area of Interest). To evaluate the effectiveness of the mission, a revisiting time was selected as a key requirement. This paper presents the mission analysis process for four SAR satellites constellation as well as the result of constellation configuration design to meet the requirements. Figure of Merits analysis was performed based on algorithm developed. Finally, it was confirmed that the constellation orbit with four different orbital planes is likely to be appropriate for ISR mission.

Use of 16S-23S rRNA Intergenic Spacer Region for identification in the fish pathogenic Streptococcus iniae (16S-23S rRNA Intergenic Spacer Region을 이용한 어류 병원성Streptococcus iniae의 분자생물학적 동정)

  • Jeong, Yong-Uk;Gang, Bong-Jo;Park, Geun-Tae;Heo, Mun-Su
    • Journal of fish pathology
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    • v.17 no.2
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    • pp.91-98
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    • 2004
  • This study was performed for the identification of Streptococcus sp. from cultured flounders (Paralichthys olivaceus) showing streptococcosis in the Jeju island. We isolated 10 strains of Streptococcus iniae from the cultured olive flounders with streptococcosis. Isolated strains were identified in S. iniae since they have formed the expected band through performing PCR assay using specific primers, Sin-1 (5'-CTAGAGTACACATGTACT(AGCT)AAG-3') and Sin-2 (5'-GGATTTTCCACTCCCATTAC-3'). In addition to 16S-23S rRNA intergenic spacers (ISR), operon structure of isolated strains showed that all strains had three 16S-23S rRNA ISR band patterns. The 16S-23S rRNA ISR sequence of isolated strains showed 96% sequence identity with S. iniae (GenBank accession number AF 048773). This paper is the first report that S. iniae is associated with streptococcosis of Olive flounder in Korea.

Interference Space Reuse and the Adoption Strategy through QoS Constraints in Three-Cell Downlink MIMO Interference Channels (3-Cell 하향링크 MIMO 간섭 채널에서의 간섭 공간 재활용 및 QoS Constraint에 따른 그 적용 방안)

  • Yoon, Jangho;Lee, Hwang Soo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.37A no.12
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    • pp.1093-1105
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    • 2012
  • We propose an interference space reuse (ISR) algorithm for the MU-MIMO design in 3-cell downlink interference channels. Also, we provide a strategy for the adoption of the ISR scheme in the cellular network. In the multicell interference channels, the cell edge users may undergo severe interferences and their signals should be protected from the interferers for reliable transmissions. However, the intra cell users do not only experience small interferences but also they require small transmission power for stable communication. We provide a vector design algorithm based on ISR, where intra cell users are served through reusing the cell edge users' interference space. The performance enhancement reaches 20% compared to the fractional frequency reuse (FFR) scheme combined with IA through the scheduling between the cell edge users and the intra cell users. Also, it can be used to enhance the cell edge throughput when the quality of service (QoS) requirements of the intra cell users are fixed.

Investigating the Induced Systemic Resistance Mechanism of 2,4-Diacetylphloroglucinol (DAPG) using DAPG Hydrolase-Transgenic Arabidopsis

  • Chae, Dae-Han;Kim, Da-Ran;Cheong, Mi Sun;Lee, Yong Bok;Kwak, Youn-Sig
    • The Plant Pathology Journal
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    • v.36 no.3
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    • pp.255-266
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    • 2020
  • Plant immune responses can be triggered by chemicals, microbes, pathogens, insects, or abiotic stresses. In particular, induced systemic resistance (ISR) refers to the activation of the immune system due to a plant's interaction with beneficial microorganisms. The phenolic compound, 2,4-diacetylphloroglucinol (DAPG), which is produced by beneficial Pseudomonas spp., acts as an ISR elicitor, yet DAPG's mechanism in ISR remains unclear. In this study, transgenic Arabidopsis thaliana plants overexpressing the DAPG hydrolase gene (phlG) were generated to investigate the functioning of DAPG in ISR. DAPG was applied onto 3-week-old A. thaliana Col-0 and these primed plants showed resistance to the pathogens Botrytis cinerea and Pseudomonas syringae pv. tomato DC3000. However, in the phlG transgenic A. thaliana, the ISR was not triggered against these pathogens. The DAPG-mediated ISR phenotype was impaired in transgenic A. thaliana plants overexpressing phlG, thus showing similar disease severity when compared to untreated control plants. Furthermore, the DAPG-treated A. thaliana Col-0 showed an increase in their gene expression levels of PDF1.2 and WRKY70 but this failed to occur in the phlG transgenic lines. Collectively, these experimental results indicate that jasmonic acid/ethylene signal-based defense system is effectively disabled in phlG transgenic A. thaliana lines.