• Title/Summary/Keyword: IRE1

Search Result 93, Processing Time 0.025 seconds

Facial Feature Extraction using Nasal Masks from 3D Face Image (코 형상 마스크를 이용한 3차원 얼굴 영상의 특징 추출)

  • 김익동;심재창
    • Journal of the Institute of Electronics Engineers of Korea SP
    • /
    • v.41 no.4
    • /
    • pp.1-7
    • /
    • 2004
  • This paper proposes a new method for facial feature extraction, and the method could be used to normalize face images for 3D face recognition. 3D images are much less sensitive than intensity images at a source of illumination, so it is possible to recognize people individually. But input face images may have variable poses such as rotating, Panning, and tilting. If these variances ire not considered, incorrect features could be extracted. And then, face recognition system result in bad matching. So it is necessary to normalize an input image in size and orientation. It is general to use geometrical facial features such as nose, eyes, and mouth in face image normalization steps. In particular, nose is the most prominent feature in 3D face image. So this paper describes a nose feature extraction method using 3D nasal masks that are similar to real nasal shape.

The Study on the Characteristics of the Load Sharing in SRM with the Parallel Operation of Phase Winding (병렬권선 운전시 SRM의 부하분담 특성에 관한 연구)

  • Lee, Sang-Hun;Park, Sung-Jun;Choi, Cheol;Ahn, Jin-Woo;Kim, Cheul-U
    • The Transactions of the Korean Institute of Power Electronics
    • /
    • v.8 no.1
    • /
    • pp.30-39
    • /
    • 2003
  • In SRM driving, the current rate is directly related to the rate of switching device and in cost reduction, the Parallel switching operation is the alternatives because it has the smaller current rate through current division. There ire many investigations for the parallel switching operations to equaling the current division. However it remains many problems for practical usage. The reason Is that the switching characteristics are mainly relied on the different saturation voltage of each device etc. and these factors are not altered by a circuit designer. In order to compensate this problem, a proper resistance is experimently inserted to the switching device. But this method can not be the optimal solution. Therefore this paper propose a new parallel operation of SRM which uses a parallel phase winding to remove the traditional effect of switching device such as saturation voltage according to the division of current. Also the reliable and stable driving is improved through experiments and the detailed principles.

Blocking Artifact Reduction Algorithm Using Similarity between Blocks and Linear Combination (블록간 유사성과 선형조합을 이용한 블록화 현상 제거 알고리듬)

  • 박경남;권기구;이건우;이석환;권성근;이건일
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.27 no.6A
    • /
    • pp.584-591
    • /
    • 2002
  • In this paper, we proposed a b1ocking artifact reduction algorithm using similarity and linear combination between blocks. In the proposed method, all of the blocks are classified into low frequency block and high frequency block according to the their DCT coefficients. And we defined range block which shows blocking artifacts, as block centered to block boundary and defied domain block as similar block with range block within search range. In the search procedure, we used sub-block's property of range block and similarity for more accurate searching. Finally blocking artifact reduction algorithm is performed using linear combination between searched domain block and blocky range block. The performance of the proposed method is investigated by computer simulation in comparison with the traditional methods. In the experimental results, Ire confirmed the better performance in the subjective by 0.04∼0.4 dB and objective image quality.

Kinematic analysis of Ire hockey slap shot (아이스 하키 슬랩 샷(slap shot)의 운동학적 분석)

  • Moon, Gon-Sung;Park, Chong-Rul
    • Korean Journal of Applied Biomechanics
    • /
    • v.13 no.2
    • /
    • pp.13-28
    • /
    • 2003
  • The purpose of this study was to analyze the kinematic characteristics of Ice hockey slap shot. The subjects of this study were four professional ice hockey players. The reflective markers were attached on the anatomical boundary line of body and the subjects were asked to perform the shot. Ariel Performance Analysis System was used to capture and digitize the shooting image, the data were analyzed by LabView 6i. The results were as fellows. 1. The period of the back swing phase was $0.542{\pm}0.062sec$, the down swing phase was $0.28{\pm}0.056sec$ and the total swing time was $0.825{\pm}0.017sec$ 2. The maximum linear velocity of the stick blade for x direction was shown after 7% of impact, for y, z direction were shown before 2%, 8% of Impact. 3. The maximum velocity of each segment for the left arm was $2.35{\pm}0.05m/s$ in the upper arm, $3.56{\pm}0.34m/s$ in the forearm, $4.75{\pm}0.67m/s$ in the hand. 4. The maximum velocity of each segment for the right arm was $4.67{\pm}0.43m/s$ in the upper arm, $7.22{\pm}0.69m/s$ in the forearm, $9.42{\pm}0.89m/s$ in the hand. 5. The angle of left elbow was generally flexed from the ready stance to the impact and was $82.26{\pm}3.45^{\circ}$ the moment of Impact. 6. The angle of the left shoulder was increased ut the down swing phase and was $78.74{\pm}4.78^{\circ}$ on the moment of impact. 7. The angle of the right shoulder was decreased in the down swing phase and increased before the impact. and the angle was $51.28{\pm}3.54^{\circ}$ on the moment of impact.

High Intensity Exercise Induced a Redistribution of Pyridoxal 5-Phosphate Levels with Different Vitamin $B_6$ Status in Rats

  • Cho, Youn-Ok
    • Nutritional Sciences
    • /
    • v.3 no.1
    • /
    • pp.31-35
    • /
    • 2000
  • The purpose of this study was to compare the changes in PLP concentrations induced by regular, moderate, and abrupt, high-intensity exercise in the plasma and tissues of vitamin B6 deficient and normal rats. Forty-eight rats were fed either a vitamin B6 deficient (-B6) diet or a normal (+B6) diet for 5 weeks and were subdivided into 4 groups:non-exercise(NE) group: regular, moderate-intensity exercise (RME) group; abrupt, high-intensity exercise (AIE) group; abrupt, high-intensity exercise and recuperation(IRE) group. The RME group was exercised on treadmill ($10^{\circ}$, 0.5-0.8km/h) for 2 hours just before sacrifice at the end of 5th week on the diet and the IER group was recuperated for three days on the diet after being exercised like the AIE group. Pyridoxal 5 -phosphate(PLP) levels were compared in the plasma, liver and skeletal muscle of the rats. Plasma PLP concentration tended to decrease in -B6 rats and tended to increase in +B6 rats with AIE. Plasma PLP concentration in both +B6 rats with AIE and no change in both -B6 and +B6 rats with RME. Muscle PLP concentration decreased in +B6 rats, showed no change in -B6 rats with AIE. Muscle PLP concentrations in both +B6 and -B6 rats did not change with RME. Plasma PLP, liver PLP and muscle PLP concentration of IER returned to those of NE in both +B6 and -B6 rats. These results suggest that changes in PLP concentration in plasma, liver and muscle occur with exercise and are affected by exercise intensity and vitamin B6 status. These changes may be due to interorgan redistribution of PLP.

  • PDF

Knock-in Somatic Cells of Human Decay Accelerating Factor and α1,2-Fucosyltransferase Gene on the α1,3-Galactosyltransferase Gene Locus of Miniature Pig (α1,3-Galactosyltransferase 유전자 위치에 사람 Decay Accelerating Factor와 α1,2-Fucosyltransferase 유전자가 Knock-in된 미니돼지 체세포)

  • Kim, Ji Woo;Kang, Man-Jong
    • Reproductive and Developmental Biology
    • /
    • v.39 no.3
    • /
    • pp.59-67
    • /
    • 2015
  • Galactose-${\alpha}1,3$-galactose (${\alpha}1,3$-Gal) epitope is synthesized at a high concentration on the surface of pig cells by ${\alpha}1,3$-galactosyltransferase gene (GGTA1). The ${\alpha}1,3$-Gal is responsible for hyperacute rejection in pig-to-human xenotransplantation. The generation of transgenic pigs as organ donors for humans is necessary to eliminate the GGTA1 gene that synthesize $Gal{\alpha}$(1,3)Gal. To prevent hyperacute graft rejection in pig-to-human xenotransplantation, previously, we developed ${\alpha}1,3$-galactosyltransferase gene-knock-out somatic cell by homologous recombination. In this study, we established cell lines of ${\alpha}1,3$-GT knock-out expressing hDAF and hHT gene from minipig fibroblasts to apply somatic cell nuclear transfer. The hDAF and hHT mRNA were expressed in the knock-in somatic cells and ${\alpha}1,3$-GT mRNA was suppressed. However, the knock-in somatic cells were increased resistance to human serum-mediated cytolysis.

Regulation of ER Stress Response on 1,2,3-Trichloropropane-Induced Hepatotoxicity of Sprague Dawley Rats (1,2,3-Trichloropropane으로 유도된 SD랫드의 간독성에서 ER 스트레스 반응의 조절)

  • Tae Ryeol Kim;You Jeong Jin;Ji Eun Kim;Hee Jin Song;Yu Jeong Roh;Ayun Seol;Eun Seo Park;Ki Ho Park;Su Jeong Lim;Su Ha Wang;Yong Lim;Dae Youn Hwang
    • Journal of Life Science
    • /
    • v.34 no.2
    • /
    • pp.113-121
    • /
    • 2024
  • Endoplasmic reticulum (ER) stress responses are markedly induced during toxic responses caused by various chemical substances, including difenoconazole, but no research has been conducted on 1,2,3-trichloropropane (TCP), a chemical that is generally used in agriculture and industry, which induces hepatotoxicity. Therefore, in this study, the changes in indicators for hepatotoxicity, apoptosis, and ER stress were analyzed in TCP-treated Sprague Dawley (SD) rats to study the regulatory mechanism of ER stress during the hepatotoxicity. The TCP-treated group decreased in body weight and dietary intake compared to the vehicle-treated group, and necrosis and vacuolation increased significantly in liver histology. In addition, the expression of apoptosis-related factors, including Bax/Bcl-2 and cleaved caspase (Cas)-3/Cas-3 increased significantly in the TCP-treated group compared to the vehicle-treated group. In the analysis of ER stress response indicators, the expression of C/EBP homologous protein (CHOP), phospho-eukaryotic translation initiation factor 2 alpha subunit (eIF2α), and phospho-inositol-requiring enzyme 1α (IRE1α) increased only in the TCP100-treated group and decreased in the TCP200-treated group. However, the transcriptions of growth arrest and DNA damage-34 (GADD34) increased in the TCP200-treated group, while Spliced X-box binding protein-1 (XBP1s) and unspliced XBP1(XBP1u) decreased in the same group. These results suggest that the ER stress response is successfully triggered during the hepatotoxicity induced by TCP treatment through the alternative regulation of the unfolded-protein response (UPR) pathway.

Ginsenoside Rb1 and compound K improve insulin signaling and inhibit ER stress-associated NLRP3 inflammasome activation in adipose tissue

  • Chen, Weijie;Wang, Junlian;Luo, Yong;Wang, Tao;Li, Xiaochun;Li, Aiyun;Li, Jia;Liu, Kang;Liu, Baolin
    • Journal of Ginseng Research
    • /
    • v.40 no.4
    • /
    • pp.351-358
    • /
    • 2016
  • Background: This study was designed to investigate whether ginsenoside Rb1 (Rb1) and compound K (CK) ameliorated insulin resistance by suppressing endoplasmic reticulum (ER) stress-induced inflammation in adipose tissue. Methods: To induce ER stress, epididymal adipose tissue from mice or differentiated 3T3 adipocytes were exposed to high glucose. The effects of Rb1 and CK on reactive oxygen species production, ER stress, TXNIP/NLRP3 inflammasome activation, inflammation, insulin signaling activation, and glucose uptake were detected by western blot, emzyme-linked immunosorbent assay, or fluorometry. Results: Rb1 and CK suppressed ER stress by dephosphorylation of $IRE1{\alpha}$ and PERK, thereby reducing TXNIP-associated NLRP3 inflammasome activation in adipose tissue. As a result, Rb1 and CK inhibited IL-$1{\beta}$ maturation and downstream inflammatory factor IL-6 secretion. Inflammatory molecules induced insulin resistance by upregulating phosphorylation of insulin receptor substrate-1 at serine residues and impairing insulin PI3K/Akt signaling, leading to decreased glucose uptake by adipocytes. Rb1 and CK reversed these changes by inhibiting ER stress-induced inflammation and ameliorating insulin resistance, thereby improving the insulin IRS-1/PI3K/Akt-signaling pathway in adipose tissue. Conclusion: Rb1 and CK inhibited inflammation and improved insulin signaling in adipose tissue by suppressing ER stress-associated NLRP3 inflammation activation. These findings offered novel insight into the mechanism by which Rb1 and CK ameliorate insulin resistance in adipose tissue.

ESTIMATION OF THE SURVIVAL RATE IN FISH POPULATION FROM THE LENGTH COMPOSITION AND THE GROWTH EQUATION1 (체장조성과 성장곡선식에서 생잔율을 추정하는 방법)

  • SHIN Sang Taek
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.10 no.2
    • /
    • pp.137-143
    • /
    • 1977
  • A study has been made to find out a new method of calculating the survival rate of a fish population from length composition and growth equation. 1. In the steady state of the fish population, let the total mortality rate be z, the age of complete recruitment $\alpha$, and the number of $\chi$ year class $N_\chi$. Then ire obtain $$N\chi=N\alpha\;\exp\;{-z(\chi-\alpha)}$$ Let the oldest age in the catch be h, the average age between the age of complete recruitment and the oldest age in the catch $U\chi$. Then we have $$U\chi=\frac{a-b\;\exp\;(-z(b-a))}{1-\exp\;(-z(b-a))}+\frac{1}{z}....(1)$$ and then let be infinite. Then we obtain $$Z=\frac{1}{U\chi-\alpha....(2)$$ 2. Calculating numerical value of $U\chi$ from age composition table and growth equation and substitute in (1) or (2) for it, we may obtain the value of s and $\varrho^{-z}$. 3. This method is applied t a case of yellow croaker in the Yellow Sea and the East China Sea. The results are as follows: Total mortality rate 0.82595 Survival rate 0.43782 95 percent confidence interval 0.43767-0.43797.

  • PDF

Effect of Copper on the Regulation of Ferroportin-1 Gene Expression (구리가 Ferroportin-1 유전자 발현 조절에 미치는 영향)

  • Park, Bo-Yoen;Chung, Ja-Yong
    • Journal of Nutrition and Health
    • /
    • v.42 no.5
    • /
    • pp.434-441
    • /
    • 2009
  • Ferroportin-1 (FPN) is a transporter protein that is known to mediate iron export from macrophages. The purpose of this study was to investigate the effect of copper on the regulation of FPN gene expression in J774 mouse macrophage cells. J774 cells were treated with various concentrations of $CuSO_4$ and RT-PCR analyses were performed to measure the steady-state levels of mRNAs for FPN and divalent metal transporter 1 (DMT1, an iron importer). Copper treatment significantly increased FPN mRNAs in a dose-dependent manner, but didn't change the levels of DMT1 mRNA. Experiments with transcriptional inhibitor actinomycin D (0.5 ${\mu}g$/mL) revealed that copper treatment did not affect the half-life of FPN mRNAs in J774 cells. On the other hand, results from luciferase reporter assays showed that copper directly stimulated the promoter activity of FPN. In summary, our data showed copper induced FPN mRNA of macrophages via a transcriptional rather than post-transcriptional mechanisms.