• Title/Summary/Keyword: IRE1

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Ceramic Foams by the Self-Blowing of Polymer (고분자의 자체발포를 이용한 세라믹 다공질체)

  • 백종원;김득중
    • Journal of the Korean Ceramic Society
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    • v.41 no.7
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    • pp.555-559
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    • 2004
  • Ceramic foams were prepared by a self-blowing process of a polysiloxane with A1$_2$O$_3$ as a filler. The release of water and ethanol vapor during the condensation reaction of the polymer triggered the pores in the polymer melt. The size. interconnectivity and shape of the pores in the ceramic foams were strongly dependent on the viscosity of the polymer melt, which could be varied by the content and size oi the filler. When the content of the filler inceased and the size of the filler decreased. the size of the pores were decreased and the thickness between the pores were increased. In the addition, the viscosity of polymer melt increased by the pretreatment at 130$^{\circ}C$ for Ire intermolecular cross linking thereby stabilizing the foam structure. The density and compressive strength of the ceramic foams were affected by the heating rate during the blowing process.

Effect of Tone Colors on Meridians by Yangdorak Diagnosis (음색(音色)이 경락(經絡)의 양도락(良導絡) 수치(數値)에 미치는 영향)

  • Son, You-Suk;Kang, Jung-Soo
    • Journal of Acupuncture Research
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    • v.22 no.4
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    • pp.87-93
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    • 2005
  • Objectives : The aims of this study were to observe how effect bell sound, water sound and drum sound have on origin regions for acupuncture of twelve meridians by yangdorak diagnosis, and to practice it clinically. Methods : Firstly, ire measured origin regions for acupuncture of twelve meridians by yangdorak diagnosis, after we relieved a subject for 10 minutes. Secondly, we measured origin regions for acupuncture of twelve meridians by yangdorak diagnosis, after a subject listened to bell sound, water sound and drum sound for 3 minutes. Results : Through testing the effects of bell sound, water sound and drum sound on numerical values of origin regions for acupuncture of twelve meridians by yangdorak diagnosis, we had follows; 1. On bell sound, the numerical values of origin regions for acupuncture of twelve meridians by yangdorak diagnosis descended from 38.8 to 28.8 in left, and from 40.4 to 30.8 in right. 2. On water sound, the numerical values of origin regions for acupuncture of twelve meridians by yangdorak diagnosis descended from 55.4 to 39.4 in left, and from 56.0 to 41.9 in right. 3. On drum sound, the numerical values of origin regions for acupuncture of twelve meridians by yangdorak diagnosis descended from 39.1 to 30.1 in left, and from 38.4 to 38.0 in right. Conclusion : Through testing the effects of tone sounds on numerical values of origin lesions for acupuncture of twelve meridians by yangdorak diagnosis, we confirmed that change of tone colors go by five elemental theory rule and have effect on enery and blood metabolism.

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An Analysis of Luminance and Chromaticity on Outdoor Lighting of Historic Buildings -focused on Namdaemun and Kwanghwamun- (휘도와 색도측면에서 본 역사적 건축물의 야간경관조명 분석 -남대문과 광화문을 중심으로-)

  • 안현태;김정태
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.15 no.1
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    • pp.36-43
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    • 2001
  • Recently, outdoor lighting of buildings has bemIre activated in national level of Korea. Therefore, this study aims to analyze the outdoor ljghting effect of historic buildings with particular reference to two traditional gates architecture - Namdaemtul and Kwanghwamun For the purpose, luminance and chromaticity of outdoor lighting are measured. The results of the study are as follows; $\circled1$ Outdoor lighting of the historic buildings were mainly illuminated by the floodlights. In addition, up-lighting and accent lighting were locally used. $\circled2$ Basements and rooflines were specially emphasized, and they represented the night image of historical buildings. $\circled3$ Chromaticity distribution of historical building was wlute during the day. However, it was yellow dL1Jing the night due to the color and color temperature of outdoor lighting.ghting.

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Electromechanical Properties of PMN-PT-PZ Composition for High Power Device (고출력 압전소자를 위한 압전 세라믹(PMN-PT-PZ)조성의 전기기계적 특성)

  • Lee, K.W.;Hong, J.K.;Jeong, S.H.;Lee, J.S.;Park, C.H.;Lim, K.J.
    • Proceedings of the KIEE Conference
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    • 1999.07d
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    • pp.1723-1725
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    • 1999
  • This paper is the study for piezoelectric properties of PMN-PT-PZ composition for high power piezoelectric device. It needs the properties such as high mechanical quality factor(Qm), high electromechanical coupling coefficient(kp) and high dielectric strain constant$(d_31)$, and the stable electromechanical properties under high vibration level. For acquiring this results, the value of x is changed in 0.1Pb$(Mn_{1/3}Nb_{2/3})O_3$+(0.9-x)$PbZrO_3+xPbTiO_3$ composition to find MPB(morphotropic phase boundary), and the piezoelectric constants is measured by resonance-antiresonance frequency method, based on IRE Standard. Also, it is measured as a function of the amount of additive, $Nb_2O_5$. When the composition is applied to high power device, the electromechanical properties is measured by laser vibrometer to confirm the reliablity under high vibration level. From these results, PMN-PT-PZ composition is shown excellent properties and capacity of application to high power device.

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Design and Implementation of Dynamic Peer Selection Scheme for Allocating Proxy-Server on Pure P2P Network Environments (순수 P2P 네트워크 환경에서 프락시-서버 할당을 위한 동적 피어 선정 기법 설계 및 구현)

  • Kim, Young-Jin;Kim, Moon-Jeong;Kim, Ung-Mo;Eom, Young-Ik
    • The KIPS Transactions:PartD
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    • v.10D no.1
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    • pp.153-160
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    • 2003
  • Recently, deployments of firewalls and NATs ire increasing to provide network security features or to solve the problem of public IP shortage. But, in these environments, peers in different firewall or NAT environments may get limited services because they cannot open direct communicate channels. This can be a significant problem in pure P2P environments where the peers should get or provide services by opening direct channels among themselves. In this paper, we propose a scheme for dynamically selecting a peer that fan be used as a proxy server. The proxy server supports the communication between the peers in different firewall or NAT environments. The proposed scheme is operating system independent and supports bidirectional communication among the peers in P2P environments. Additionally, the proposed scheme can distribute network traffic by dynamically allocating proxy servers to the peers that is not located in the firewall or NAT environments.

Development of a Reporter System Monitoring Regulated Intramembrane Proteolysis of the Transmembrane bZIP Transcription Factor ATF6α

  • Kim, Jin-Ik;Kaufman, Randal J.;Back, Sung Hoon;Moon, Ja-Young
    • Molecules and Cells
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    • v.42 no.11
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    • pp.783-793
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    • 2019
  • When endoplasmic reticulum (ER) functions are perturbed, the ER induces several signaling pathways called unfolded protein response to reestablish ER homeostasis through three ER transmembrane proteins: inositol-requiring enzyme 1 (IRE1), PKR-like ER kinase (PERK), and activating transcription factor 6 (ATF6). Although it is important to measure the activity of ATF6 that can indicate the status of the ER, no specific cell-based reporter assay is currently available. Here, we report a new cell-based method for monitoring ER stress based on the cleavage of $ATF6{\alpha}$ by sequential actions of proteases at the Golgi apparatus during ER stress. A new expressing vector was constructed by using fusion gene of GAL4 DNA binding domain (GAL4DBD) and activation domain derived from herpes simplex virus VP16 protein (VP16AD) followed by a human $ATF6{\alpha}$ N-terminal deletion variant. During ER stress, the GAL4DBD-VP16AD(GV)-$hATF6{\alpha}$ deletion variant was cleaved to liberate active transcription activator encompassing GV-$hATF6{\alpha}$ fragment which could translocate into the nucleus. The translocated GV-$hATF6{\alpha}$ fragment strongly induced the expression of firefly luciferase in HeLa Luciferase Reporter cell line containing a stably integrated 5X GAL4 site-luciferase gene. The established double stable reporter cell line HLR-GV-$hATF6{\alpha}$(333) represents an innovative tool to investigate regulated intramembrane proteolysis of $ATF6{\alpha}$. It can substitute active pATF6(N) binding motif-based reporter cell lines.

Industrial and Innovation Networks of the Long-live Area of Honam Region (호남 장수지역의 산업 연계와 혁신 네트워크)

  • Park Sam Ock;Song Kyung Un;Jeong Eun Jin
    • Journal of the Korean Geographical Society
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    • v.40 no.1 s.106
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    • pp.78-95
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    • 2005
  • The purpose of this paper is to analyze industrial and innovation networks of long-live area of Honam Region and to suggest a policy direction for regional development of rural areas where have been neglected in the knowledge-based information society. Four counties (Sunchang, Damyang, Gokseong, and Gurye) in the Southwestern region of Korea are regarded as long-live belt of Korea. Production and innovation networks :Ire analyzed based on intensive surveys of firms in the belt. Major findings from the surveys are as follows. First, there are considerably strong local networks of production firms in terms of supply of input materials and labor. There are strong backward industrial linkages of the production firms with agricultural activities and considerable forward linkages with tourism industry. In addition, Internet is becoming a useful tool for sales of the new products. Second, the analysis of the innovation networks in the long-live area suggests the development of 'virtual innovation cluster' in the era of knowledge-based information society. The results imply that this innovation networks can be developed as a virtual innovation cluster in the rural areas, which can be the basis for the development of rural innovation systems.

4-phenylbutyric Acid Regulates Collagen Synthesis and Secretion Induced by High Concentrations of Glucose in Human Gingival Fibroblasts

  • Lee, Geum-Hwa;Oh, Hyo-Won;Lim, Hyun-Dae;Lee, Wan;Chae, Han-Jung;Kim, Hyung-Ryong
    • The Korean Journal of Physiology and Pharmacology
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    • v.15 no.6
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    • pp.345-351
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    • 2011
  • High glucose leads to physio/pathological alterations in diabetes patients. We investigated collagen production in human gingival cells that were cultured in high concentrations of glucose. Collagen synthesis and secretion were increased when the cells were exposed to high concentrations of glucose. We examined endoplasmic reticulum (ER) stress response because glucose metabolism is related to ER functional status. An ER stress response including the expression of glucose regulated protein 78 (GRP78), C/EBP homologous protein (CHOP), inositol requiring enzyme alpha (IRE-$1{\alpha}$) and phosphoreukaryotic initiation factor alpha (p-eIF-$2{\alpha}$) was activated in the presence of high glucose. Activating transcription factor 4 (ATF-4), a downstream protein of p-eIF-$2{\alpha}$ as well as a transcription factor for collagen, was also phosphorylated and translocalized into the nucleus. The chemical chaperone 4-PBA inhibited the ER stress response and ATF-4 phosphorylation as well as nuclear translocation. Our results suggest that high concentrations of glucose-induced collagen are linked to ER stress and the associated phosphorylation and nuclear translocation of ATF-4.

Three-dimensional shape measurement using grating patterns form an optical spatial modulator

  • Tsujioka, Katsumi;Ito, Hiroshi;Furuhashi, Hideo;Higa, Shuntaro;Hayashi, Niichi;Yamada, Jun;Hatano, Kazuo;Uchida, Yoshiyuki
    • 제어로봇시스템학회:학술대회논문집
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    • 1994.10a
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    • pp.561-565
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    • 1994
  • An automatic measuring system of three dimensional shape by a projection method with grating pattern from in optical spatial modulator has been developed. The characteristics of the system were studied. This system is composed of a projector, an optical spatial modulator, a CCD camera, and computer. A liquid crystal is used as the optical spatial modulator. The grating patterns that ire projected on the surface of the object are controlled by the computer connected with the optical spatial modulator. The projector patterns are measured by the CCD camera. The data are transferred to the computer. After a transformation into line data, the data are analyzed to obtain the coordinate of the surface of the object. This system has advantages as follows. (1) It is possible to capture the surface topography without any contact. (2) The time required for the measurements is shorter than the light-section method. (3) An optical spatial modulator using a liquid crystal is possible to control the grating patterns accurately by a computer. Surfaces of a plate and a cylinder were measured. The threshold level had an influence on the measurement. It was shown that this system has adequae accuracy in the measurements.

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The Embodiment of the Real-Time Face Recognition System Using PCA-based LDA Mixture Algorithm (PCA 기반 LDA 혼합 알고리즘을 이용한 실시간 얼굴인식 시스템 구현)

  • 장혜경;오선문;강대성
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.41 no.4
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    • pp.45-50
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    • 2004
  • In this paper, we propose a new PCA-based LDA Mixture Algorithm(PLMA) for real-time face recognition system. This system greatly consists of the two parts: 1) face extraction part; 2) face recognition part. In the face extraction part we applied subtraction image, color filtering, eyes and mouth region detection, and normalization method, and in the face recognition part we used the method mixing PCA and LDA in extracted face candidate region images. The existing recognition system using only PCA showed low recognition rates, and it is hard in the recognition system using only LDA to apply LDA to the input images as it is when the number of image pixels ire small as compared with the training set. To overcome these shortcomings, we reduced dimension as we apply PCA to the normalized images, and apply LDA to the compressed images, therefore it is possible for us to do real-time recognition, and we are also capable of improving recognition rates. We have experimented using self-organized DAUface database to evaluate the performance of the proposed system. The experimental results show that the proposed method outperform PCA, LDA and ICA method within the framework of recognition accuracy.