• Title/Summary/Keyword: IRB

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Relationship Between Life Style and Obesity Indices in Adults Using Data from Health Examination (건강검진자료에 의한 일반 성인의 생활습관과 비민지표와의 관련성)

  • Lim, Young-A;Lee, Kwang-Sung;Cho, Young-Chae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.5
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    • pp.3243-3256
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    • 2015
  • The purpose of this study was to obtain the relationship between life styles and obesity indices, and to investigate the influence of life styles on obesity indices among adults who examined health checkup in an university hospital. The subjects for this study were 4,112 adults who underwent medical examinations at a health center of a university hospital in Daejeon city from Jan 2012 to Dec 2013. We surveyed the life styles and obesity indices of study subjects from self-recorded questionnaires and medical examination charts after confirmed IRB of the hospital. As a results, the levels of obesity indices of subjects was closely correlated with increasing age, and life styles as alcohol drinking, smoking, regular exercise, overeating, meat consumption. The influence of life styles on obesity indices was incident in female than in male. And the main risk factors were regular exercise factor in obesity indices in both sex.

Effect of Health Beliefs and Critical Thinking Disposition on the Performance of Taking Standard Precautions of Nursing Students (간호대학생의 감염관리 건강신념과 비판적 사고성향이 감염관리 표준주의 수행도에 미치는 영향)

  • Kim, Yunyoung
    • Journal of Convergence for Information Technology
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    • v.11 no.11
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    • pp.85-94
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    • 2021
  • In this study, the effects of infection control health beliefs and critical thinking tendencies of nursing students on infection control standards were investigated. This study collected and analyzed the data of 222 nursing students from the College of Nursing located in City A from June 2021 to July 2021. Data were collected according to IRB-approved contents, and the collected data were analyzed using the SPSS 26.0 Statistics Program. The infection control health beliefs and critical thinking tendencies of nursing students affect the performance of standard infection control precautions(F=16.634, p<.001), and the explanatory power of the model was 22.0%. It is necessary to develop a nursing education program to improve health beliefs and critical thinking disposition and systematic and efficient infection control education to improve the performance of standard precautions for infection control of nursing students.

Ethical Considerations in Hospice and Palliative Care Research (호스피스 완화의료 연구에서의 윤리적 고려사항)

  • Youn, Gahyun
    • Journal of Hospice and Palliative Care
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    • v.22 no.2
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    • pp.49-66
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    • 2019
  • Along with the advances in medical technology and the economic development, more terminally ill patients are receiving hospice and palliative care services. Moreover, hospice and palliative care clinicians have been showing considerable interest in studies that aim to improve the quality of said care for patients and their families. Meanwhile, after the government has strengthened its policy to protect research participants, the institutional review boards (IRBs) are more closely examining various ethical issues related to patients' vulnerability when reviewing protocols for hospice and palliative care research. However, terminally ill patients should be provided with guaranteed qualities of hospice and palliative care to improve and maintain their quality of life. To that end, support should be provided for efforts to conduct ethical and safe studies with hospice and palliative care patients. Thus, this review paper proposes ethical guidelines for hospice and palliative care research. The guidelines could be appropriately used as a reference for researchers who should prepare for ethically safe and scientifically valued research protocols and the IRBs that will review the protocols.

Randomized, Double-blind, and Placebo-controlled Human Trial to Evaluate the Efficacy and Safety of Allium Fistulosum L. Root Extract on Improvement of Child Height Growth: Study Protocol (총백추출물의 어린이 키 성장에 대한 유효성 및 안전성을 평가하기 위한 무작위배정, 이중눈가림, 위약 대조 인체적용시험: 인체적용시험 프로토콜)

  • Shim, Soo Bo;Ko, Byoung Seob;Ryuk, Jin Ah;Lee, Jung Hwan;Lee, Ho Bong;Ha, Ki Chan;Kim, Yeung Mi;Lee, Hye Lim
    • The Journal of Pediatrics of Korean Medicine
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    • v.35 no.2
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    • pp.11-20
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    • 2021
  • Objectives The purpose of the study is to evaluate the safety of the Allium Fistulosum extract in children and its effectiveness in height growth. Methods This study is randomized, double-blind, placebo-controlled trial. The participants are children between the 3rd and 25th percentiles in height, and between the ages of 5 and 12 years. They are randomly assigned to treatment group or control group. The treatment group will take 5 g (1 g as Allium Fistulosum extract) for 24 weeks, 1 time a day. The control group will take the 5 g (0 g as Allium Fistulosum extract) of placebo for 24 weeks, 1 time a day. The primary outcome is change in height, and the secondary outcomes are growth rate, height standard deviations, Insulin-like growth factor-1 (IGF-1), Insulin-like growth factor binding protein-3 (IGFBP-3), IGF1-1/IGFBP-3 ratio, growth hormone, bone age, osteocalcin, and Z-score for growth. Results This protocol has been approved by the institutional review board (IRB) of Daejeon Korean Medicine Hospital of Daejeon University (IRB No. DJDSKH-20-BM-15), and registered in the Clinical Research Information Service (CRIS) (Registry No. KCT0005981). Conclusions This study will provide clinical information about the effectiveness and safety of Allium Fistulosum extract in children for their growth.

Literature Review of the Safety Studies among Nursing Students (간호대학생 대상 안전 관련 국내 연구 동향)

  • Lee, Seonhye
    • The Journal of the Convergence on Culture Technology
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    • v.8 no.1
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    • pp.131-138
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    • 2022
  • This study was to investigate the characteristics of nursing students' safety by reviewing literature reported in Korea. Methods: A total of 29 articles were selected by the combination with 'safety', 'safety*', 'patient safety', 'patient safety*' 'nursing students', and 'nursing * students' from the database(via DBpia, KCI, KISS, NANET, NDSL, NL, RISS). Results: Publication year of researchs are '2015-2019' 69.0%, publication journal 'non-nursing' 79.3%, mean of participants 242.4 persons, 'under 200 persons' 51.7%, number of participating area 'one region' 48.2%, number of participating schools 'over three schools' 42.3%, participating grade 'senior in colleges' 56.2%. Participant were calculated by G*Power and unapproved by Institutional Review of Board(IRB) were 58.6%. Most of statistics measures were 'regression' 75.9%, and authors' number were '2 co-authors' 58.6%. In keyword analysis, it has changed from knowledge-oriented to patient-centered. Conclusion: Future research will require research and policy support for the development of an integrated educational approach and intervention plan to strengthen the safety competency of nursing students.

Convergent Influence of Career Preparation Behavior of Nursing College Students (간호대학생의 진로준비행동의 영향요인)

  • Yun, Ju-Hui;Yun, Hye-won
    • Journal of Digital Convergence
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    • v.19 no.11
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    • pp.279-285
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    • 2021
  • This study attempted to provide basic data for educational programs to improve career preparation behaviors by identifying the effects of nursing students' self-esteem and empathy on career preparation behaviors. Nursing Students and the 150 people who underwent descriptive research targets, data collection period was done by November 30, 2019 from IRB approval. The data were analyzed correlations between variables were analyzed using Pearson's correlation coefficient, and stepwise multiple regression analysis was used to determine the factors that affect the clinical performance of the Nursing Students (SPSS 23 version). As a result of the study, empathy ability was positively correlated with gender (r=.179, p=.029), self-esteem was negatively correlated with academic performance (r=-.231, p=.005), career preparation behavior showed a positive correlation with the number of practice hospitals(r=.178, p=.030). As the empathy ability of nursing students improved (β=.19, p=.020), career preparation behavior increased. Through this, the study is meaningful in that it suggested the need and direction to maintain a positive attitude toward career preparation behaviors of nursing students. suggest.

Randomized, Double-blind, and Placebo-controlled Human Trial to Evaluate the Efficacy and Safety of Humulus japonicus Extract Powder on Child Height Growth: Study Protocol (소아 키 성장에 미치는 한삼덩굴추출분말의 유효성 및 안전성을 평가하기 위한 무작위배정, 이중눈가림, 위약 대조 인체적용시험: 인체적용시험 프로토콜)

  • Jang Subi;Choi Bom;Cheon Jin Hong;Kim Ki Bong
    • The Journal of Pediatrics of Korean Medicine
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    • v.37 no.3
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    • pp.121-132
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    • 2023
  • Objectives We aimed to confirm whether Humulus japonicus Extract Powder can enhance child height growth significantly and safely compared with a placebo. Methods A total of 150 children between the 3rd and 25th percentiles in height and between the ages of 6 and 9 years will be recruited to participate in this randomized, double-blind, placebo-controlled clinical trial. The participants will be randomly assigned to the treatment or placebo group. Participants in the treatment group will take one pack per day (700 mg of Humulus japonicus Extract Powder) for 24 weeks. Participants in the placebo group will take one package of placebo per day (0 mg of Humulus japonicus Extract Powder) for 24 weeks. The primary outcome will be a change in height after 12 weeks, and the secondary outcomes will be the height after 24 weeks, growth rate, height standard deviation, growth hormone, insulin-like growth factor-1 (IGF-1), insulin-like growth factor binding protein-3 (IGFBP-3), bone alkaline phosphatase (BALP), and osteocalcin after 12 and 24 weeks. Results This protocol was approved by the Institutional Review Board (IRB) of the Korean Medicine Hospital of Busan University (IRB No. PNUKHIRB-2023-03-002). Research participants will be recruited from June 2023 to December 2023. Conclusions The results of this study provide clinical information regarding the effectiveness and safety of the Humulus japonicus Extract Powder in increasing child height.

Effects of Ethical Consciousness on Job Satisfaction of Social Workers: Mediated Effects of Self-efficacy (사회복지사의 윤리의식이 직무만족에 미치는 영향: 자기효능감의 매개효과)

  • Jong-Du Park;Mal-Sook Suk
    • Journal of Industrial Convergence
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    • v.21 no.3
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    • pp.149-157
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    • 2023
  • The purpose of this study was to verify the mediating effect of self-efficacy in the effect of social workers' ethical consciousness on job satisfaction. Based on the ratio of the statistical yearbook of Korean social workers in 2020, the subjects of the study conducted an online survey on 512 social workers working at social welfare facilities in Seoul. The study was conducted with IRB approval. The analysis and statistics of this study used SPSS & AMOS 25.0. Bootstrapping was used to verify the mediating effect of self-efficacy in the effect of social workers' ethical consciousness on job satisfaction. As a result of the study, the positive effect on self-efficacy and job satisfaction of social workers was verified. In addition, the positive mediating effect of self-efficacy was verified between the ethical consciousness of social workers on job satisfaction. The results of the study suggest the importance of systems and practices to support capacity building and promote self-efficacy for ethical awareness to improve job satisfaction of social workers.

Classification of Nasal Index in Koreans According to Sex

  • Sung-Suk Bae;Hee-Jeung Jee;Min-Gyu Park;Jeong-Hyun Lee
    • Journal of dental hygiene science
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    • v.23 no.3
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    • pp.193-198
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    • 2023
  • Background: The nose is located at the center of the face, and it is possible to determine race, sex, and the like. Research using the nasal index (NI) classification method to classify the shape of the nose is currently in progress. However, domestic research is required as most research is being conducted abroad. In this study, we used a 3D program to confirm the ratio of the nose shape of Koreans. Methods: One hundred patients (50 males and 50 females) in their 20s were evaluated (IRB approval no. DKUDH IRB 2020-01-007). Cone beam computed tomography was performed using the Mimics ver.22 (Materialise Co., Leuven, Belgium) 3D program to model the patient's skull and soft tissues into three views: coronal, sagittal, and frontal. To confirm the ratio of measurement metrics, analysis was performed using the SPSS ver. 23.0 (IBM Co., Armonk, NY, USA) program. Results: Ten leptorrhine (long and narrow) type, 76 mesorrhine (moderate shape) type, and 14 platyrrhine (broad and short) type noses were observed. In addition, as a result of sex comparison, five males had the leptorrhine (long and narrow) type, 40 mesorrhine (moderate shape), and five platyrrhine (broad and short) types. For females, five patients had the leptorrhine (long and narrow) type, 36 patients had the mesorrhine (moderate shape) type, and nine patients had the platyrrhine (broad and short) type. Conclusion: This study will be helpful when performing nose-related surgeries and procedures in clinical practice and for similar studies in the future.

A Study of the Whitening Activities of Magnolia obovata Bark Ethyl Acetate Fractions as Cosmetic Ingredient (화장품 소재로서 후박 에틸아세테이트 분획물의 미백활성에 관한 효과)

  • Kang, Hee Cheol;Joo, Kwang Sik;Joo, Se Jin;Ha, Young Ae;Kim, Hack Soo;Cha, Mi Yeon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.43 no.1
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    • pp.43-52
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    • 2017
  • EtOAc fractions of Magnolia obovata (M. obovata) Bark extracts were studied for the potential ingredient as a safe and effective whitening cosmetic material. The concentration of active substances honokiol was determined by HPLC. In vitro, the fractions reduced the extracellular and intracellular melanin contents in B16F10 cells in dose dependently and inhibited extracellular melanin secretion ($IC_{50}=11.05{\mu}g/mL$). The $12.5{\mu}g/mL$ treatment of maximum concentration effectively inhibited up to about 60% to the amount of extracullular melanin. Also, the $12.5{\mu}g/mL$ treatment of maximum concentration effectively inhibited up to about 59% to the amount of intracullular melanin ($IC_{50}=10.85{\mu}g/mL$). The $IC_{50}$ value of ${\alpha}-arbutin$ used as a positive control was $59.99{\mu}g/mL$. So, EtOAc fractions of M. obovata Bark extracts showed whitening effect when compared with the non-treatment group. In case of in vivo study, Cosmetic cream with EtOAc fractions of M. obovata Bark extracts was approved by Ethics committee of KDRI (IRB number: KDRI-IRB-1537). As a result in progress for skin sensitization as well as assessment of skin irritation through repeated patch test, skin allergens was identified as non sensitizing agents. Also, cosmetic cream with EtOAc fractions of M. obovata Bark extracts showed significant topical whitening effect and reliable skin safety when compared with the non-treatment group. In conclusion, EtOAc fractions of M. obovata Bark extracts may be a useful cosmetic ingredient for effective skin whitening.