• The Journal of KAIRB
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• v.1 no.2
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• pp.23-29
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• 2019

"Conflict of Interest(COI)" is defined as a situation where a person or an institution is involved in multiple interests, and an interest is against the others. COI in medical researches should well addressed and managed in order not to breach the integrity of the research. Numbers of methods have been introduced to manage the COI. In this article, the concept of COI and its application to medical researches is reviewed and the methods evading COI are introduced.

• Clinical and Experimental Reproductive Medicine
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• v.39 no.4
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• pp.138-143
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• 2012

While Korea does not have any legal statement on surrogacy, treatments are carried out in practice. As a result, every Institutional Review Board (IRB) of each fertility clinic faces an ethical predicament in reviewing each case. There is a need to arrange the institutions' own standards of surrogate pregnancy procedures before the establishment of national or professional regulation. This article examines the legal, social, and medical issues of surrogacy to help IRBs to judge their cases.

• The Journal of the Convergence on Culture Technology
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• v.1 no.2
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• pp.53-64
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• 2015

The purpose of this study was to analyze the smoking experience and attitude including affect factors to smoking for elementary schoolers. The cross-sectional descriptive study design was used. We selected 810 students from 14 elementary school located in Chungchung-do and Gangwon-do by convenience random sampling and received IRB from Y Univ. 810 students were included in the final analysis using generalized linear model. Among 810 students, 7.3% of students reported to have smoking experience. The result of analyzing the smoking affect factors for smoking students who were having friends who had smoking experience, unable to smoking suggestion and those who were male, had significantly more smoking experience. According to the results of this study, there should be an intensive tailed smoking related program development for male elementary students, especially for smokers who have smoking friend and including smoking refusing program. And the school system services of elementary school should be strengthened to protect the elementary students from further the critical situation caused by smoking experience.

• Korean Journal of Clinical Pharmacy
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• v.25 no.3
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• pp.166-170
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• 2015

Background: Primary warm autoimmune hemolytic anemia (AIHA) is a relatively rare hematologic disorder resulting from autoantibody production against red blood cells. There has been very few studies about primary warm AIHA in South Korea because of its low incidence. We retrospectively analyzed the treatment outcome of primary warm AIHA. Method: We reviewed retrospectively the medical records of 9 primary warm AIHA patients from December 2002 to January 2015. We analyzed the causes and clinical characteristics of primary warm AIHA patients. We retrospectively analyzed the clinical data in electronic medical records for 9 Korean patients with AIHA patients who were diagnosed during the period from December 2002 to January 2015 at the Regional University Hospital in Korea. The study protocol was approved by the Institutional Review Board (IRB #2015-08-007, Chosun University Hospital IRB). Results: The mean age was 52 years (range 27~78), the mean hemoglobin level was 5.0 g/dL (range 2.5~6.4 g/dL). All patients received steroids at therapeutic dosages (corticosteroid 1 mg/Kg) as first line treatment. Eight of them showed complete response (5/8, 62.5%) and partial response (3/8, 37.5%), one patient required second-line treatment with rituximab. Two patients who responded first line treatment were relapsed at 86 weeks and 24 weeks after response, respectively. Only one patient of them was retreated with corticosteroid because of anemic symptoms. Conclusion: This study indicates that oral corticosteroid is an effective therapy for primary warm AIHA.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.3
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• pp.392-398
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• 2012

This research aims to analyze the ethical requirements and to find the problems for the publication guidelines of oriental medicine journals. A total of 13 domestic journals, related to oriental medicine and registered in 'National Research Foundation of Korea' list, were selected for the analysis of ethical requirements. We inquired the revised year of the publication guideline and the status of ethics committee of selected journals. The ethical requirements of publication guidelines were evaluated by categorizing them into Institutional Review Board(IRB), Helsinki Declaration, Informed Consent, confidentiality and anonymity of subjects, and conflict of interest. In the case of revised year of the publication guidelines, the year of the most recently revised journal was 2011. However, the revised year of publication guidelines were not announced for three journals and a few journals haven't revised the publication guidelines since 2002. In the case of ethics committee status, four journals out of 13 journals maintained the ethics committee. In the result of ethical requirement analysis, nine journals included the information for confidentiality and anonymity of subjects, and four journals included the information for Helsinki Declaration and Informed Consent. However, only one journal included the information for IRB and conflict of interest. Recently, the importance of clinical researches has been increased to prove the effect of oriental medicine scientifically and objectively. The clinical researches should be considered in scientific side and ethical side as well, because they have potential risks to human subjects. In this sense, announcing the ethical requirements in the publication guidelines can be one way to secure the morality of researches. Thus, it is required to prepare correct publication guidelines and ethical requirements in oriental medicine journals.

• Journal of Sasang Constitutional Medicine
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• v.23 no.4
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• pp.514-525
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• 2011

1. Objectives This study aims to find out identify the recognition and attitude about the research ethic among Constitutional medicine researchers. 2. Methods This survey was conducted to the 37 researchers who were currently participating in Korea Constitution Multicenter Study guided by Korea institute of Oriental medicine(KIOM). The survey consist of 4 parts that level of acknowledgment about the systems and laws on clinical research ethic, clinical research experiences and education, the level of acknowledgment about Institutional Review Board(IRB) and the recognition about overall research ethic. 3. Results Thirty one questionnaires were collected. Most researchers had low level of acknowledgment about the guidelines of basic research ethic. It was proved that more than 65% of the respondents have never received education for clinical research ethic. Moreover, 70% of them felt the need for education of clinical research ethic. In addition, most of the respondents recognized the fact that IRB is responsible for ethically implementing clinical research. 39% of the researchers thought that they themselves have a firm ethical viewpoint, while the rest of the group showed somewhat difficulty on their own ethical implementation of clinical research. 4. Conclusions Most of researcher had partial awareness of regulations and laws on clinical research ethic. And Educational needs of research ethic was high. Therefore education and Public Relations need to be done to extend research ethic. Moreover, standardized course of education on research ethic should be developed and activated.

• Journal of Korean Critical Care Nursing
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• v.6 no.2
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• pp.78-88
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• 2013

Purpose: The purpose of this study was to identify the trends in studies published in Journal of Korean Critical Care Nursing (JKCCN) from 2008 to 2013. Methods: A total of 65 studies published between 2008 to 2013 were reviewed using criteria developed by researchers. Results: Approximately 36% of studies were conducted with patients. Intensive care unit (ICU) was the most popular site as the study setting. Among 59 research papers, 42.4% were approved by institutional review board (IRB). Quantitative studies were 78.6%, while qualitative studies were 4.6%. The research designs for the quantitative studies were survey (52.3%), quasi-experimental (16.9%), and so on. There was no randomized controlled trial. The most frequently used methods to provide nursing intervention was education. In addition, "nurse" and "ICU" were most commonly used keyword. Conclusion: Considering the low rate of IRB approval, more stringent application of research ethics is necessary to improve the quality of JKCCN. In addition, more randomized controlled trials should be encouraged to support evidence-based practice in critical care.

• Journal of Acupuncture Research
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• v.32 no.2
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• pp.11-21
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• 2015

Objectives : To improve quality of clinical research for acupuncture and moxibustion, a guideline for clinical research protocol is needed. While developing a guideline for acupuncture and moxibustion clinical research, we reviewed the ethical and scientific aspects of protocols pointed out by the institutional review board. This will offer practical assistance to the researchers. Methods : Ethical and scientific aspects of acupuncture and moxibustion research protocols reviewed by Kyung Hee University Korean Medicine Hospital Institutional Review Board were gathered and reviewed. Results : Ethical and scientific aspects of protocol review was reported. Conclusions : The example of review will be helpful for new researchers when developing acupuncture and moxibustion clinical research protocol.

• The Journal of the Convergence on Culture Technology
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• v.1 no.1
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• pp.15-26
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• 2015

The purpose of this study was to analyze the sexual related predicting factors for Female University students in Korea. The cross-sectional descriptive study design was used. We selected 320 students from 6 Universities located in Seoul, Chungchung-do and Gangwon-do by convenience random sampling and received IRB from Y Univ. 299 students were included in the final analysis using logistic regression. Among 299 students, 60.2% of students reported to have sexual experience. The result of analyzing the related factors to sexual experience revealed that the students who were having friends who had sexual experience, smokers and those who were high grade, had significantly more sexual experience. According to the results of this study, there should be an intensive and female tailed sexual related program development for the University students, especially for smokers and including smoking cessation program. And the school health services of University combined general staff working should be strengthened to protect the University students from the critical situation caused by unwanted sexual experience.

• Journal of the Mineralogical Society of Korea
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• v.23 no.2
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• pp.107-115
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• 2010

Removal and mineralization of dissolved uranium by bacteria in KURT (KAERI Underground Research Tunnel), Korea Atomic Energy Research Institute (KAERI) was investigated. Two different bacteria, IRB (iron-reducing bacteria) and SRB (sulfate-reducing bacteria) was used, and minerals formed by these bacteria were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). Compared to uranyl ions, ferric ions were preferentially reduced by IRB, showing that there is no significant reduction and removal of uranium. However, uranium concentration considerably decreased by addition of Mn(II). Results show that a sulfide mineral such as mackinawite (FeS) is formed by SRB respiration through combination of Fe(II) and S without manganese sulfide formation. In the presence of Mn(II), however, uranium is removed effectively, suggesting that the sorption and incorporation of uranium could be affected by Mn(II) onto the sulide minerals.