• Journal of the Korean Applied Science and Technology
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• v.29 no.1
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• pp.116-121
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• 2012

In this paper, yellow coupler was prepared by the reaction of ${\alpha}$-pivaloyl- 2-chloro-5-aminoacetaniline hydrogen chloride with 1-hexadecane sulfonyl chloride in the presence of pyridine. The product was identified by using various analytical tools such as melting poin elemental analyzer, IR spectrophotometer, UV-Vis spectrophotometer, mass spectrometer. The reaction of yellow coupler with CD-3(color development agent) was shown yellow color.

• Bulletin of the Korean Chemical Society
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• v.22 no.1
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• pp.59-62
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• 2001

The dried fruit-body of Daedaleopsis tricolor was extracted by the petroleum ether. The extracts were purified by liquid-liquid extraction, column chromatography, and recrystallization. The purified compound was a colorless orthorhombic crystal form. Its melting point, molecular weight and molar extinction coefficient $(\varepsilon)$ were estimated $168-170^{\circ}C$, 424 and 3,935 at 208 nm, respectively. Its structure was elucidated to be 20(29)-lupen-3-one by UV-Vis, FT-IR, NMR and X-ray crystallographic analysis. It showed antifungal activities against Saccharomyces cerevisiae and Microsporum gypseum, and antibacterial activities against Escherichia coli, Proteus vulgaris, Pseudomonas pyocyanea, Bacillus subtilis, and Staphylococcus aureus. In addition, this compound showed an antioxidative activity on lipid-peroxidation by 6.4%.

• Natural Product Sciences
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• v.29 no.2
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• pp.113-119
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• 2023

Descurainia sophia seeds methanol extract showed significant anti-influenza activity and we tried to isolate anti-influenza compounds from the D. sophia extract. D. sophia seeds were extracted with 80% methanol and fractionated with n-hexane, ethyl acetate, CHCl₃ and n-butanol. The anti-influenza activity of each fraction was assessed using sulforhodamine B (SRB) method in A549 cells, human-derived lung cancer cells. The ethyl acetate and CHCl₃ fractions showed the most potent anti-influenza activity. Seven compounds were isolated from CHCl₃ fraction and identified 1-decanol (1), 2-(3,4-dihydroxy-2-methylenebutoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (2), daucosterol (3), isorhamnetin (4), quercetin (5), sinapic acid (6), and helveticoside (7) by spectroscopic data such as UV, IR, ¹H-NMR, ¹³C-NMR and mass spectroscopy. Anti-influenza activities of isolated compounds were evaluated using SRB method in A549 cells. Compounds 3, 4 and 7 had significant anti-influenza activity in a dose-dependent manner.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.38
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• pp.29.1-29.9
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• 2016

Background: The objective of this study was to evaluate xenograft degradation velocity when treated with 4-hexylresorcinol (4HR). Methods: The scapula of a cow was purchased from a local grocery, and discs (diameter 8 mm, thickness 1 mm) were prepared by trephine bur. Discs treated with 4HR were used as the experimental group. Untreated discs were used as the control. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), antibacterial test, endotoxin test, and scanning electron microscopy (SEM) were performed on the discs. In vivo degradation was evaluated by the rat calvarial defect model. Results: The XRD and FT-IR results demonstrated successful incorporation of 4HR into the bovine bone. The experimental disc showed antibacterial properties. The endotoxin test yielded results below the level of endotoxin contamination. In the SEM exam, the surface of the experimental group showed needle-shaped crystal and spreading of RAW264.7 cells. In the animal experiments, the amount of residual graft was significantly smaller in the experimental group compared to the control group (P = 0.003). Conclusions: In this study, 4HR was successfully incorporated into bovine bone, and 4HR-incorporated bovine bone had antibacterial properties. In vivo experiments demonstrated that 4HR-incorporated bovine bone showed more rapid degradation than untreated bovine bone.

• Polymer(Korea)
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• v.24 no.4
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• pp.571-577
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• 2000

A new type of filler for epoxy-clay nanocomposites has been prepared by the reaction of octadecyltrimethylammonium bromide and layered sodium montmorillonite (MMT) via an ion-exchange reaction. The gallery space was further modified by grafting the aminopropyl groups via a reaction between a octadecyltrimethylammonium-MMT and 3-aminopropyltriethoxysilane (APS). The interlayer modification of MMT was confirmed by XRD, IR, and solid-state $^{29}$ Si CP/MAS NMR. Furthermore, clay-polymer nanocomposites have been synthesized by the polymerization of diglycidyl ether of bisphenol A(DGEBA) and $C_{18}$ H$_{37}$ N($CH_3$)$_3$-APS-MMT. The resulting hybrid nanocomposites were characterized by XRD, transmission electron microscopy (TEM) and scanning electron microscopy (SEM). The results proved that the organomontmorillonite could be exfoliated and uniformly dispersed in the epoxy matrix.

• Journal of the Korean Applied Science and Technology
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• v.29 no.3
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• pp.459-465
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• 2012

We had synthesized a green dopant material based on the binaphthyl group, 7,7'-(2,2'dimethoxy-1,1'-binaphthyl-3,3'-diyl) bis(4-(thiophen -2-yl) benzo[e][1,2,5] thiadiazole (TBT). We also fabricated the white organic light emitting diode (OLED) with a phosphorescent blue emitter : iridium(III)bis[(4,6-di-fluoropheny)-pyridinato -N,C2]picolinate (FIrpic) doped in N,N'-dicarbazolyl-3,5-benzene (mCP) of hole transport type host material and both TBT and bis(2-phenylquinolinato)- acetylacetonate iridium(III) (Ir(pq)2acac) doped in 1,3,5-tris(N-phenylbenzimidazole -2-yl)benzene (TPBi) of electron transport type host material. As a result, the property of white OLED using TBT, which demonstrated a maximum luminous efficiency and external quantum efficiency of 5.94 cd/A and 3.23 %, respectively. It also showed the pure white emission with Commission Internationale de I'Eclairage (CIE) coordinates of (0.34, 0.36) at 1000 nit.

• Journal of the Korean Applied Science and Technology
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• v.29 no.3
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• pp.429-434
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• 2012

A kind of Antihistamines, Azelastine HCl which known as modern H1-blockers, was synthesized by four step process using phthalic anhydride, 4-chlorophenylacetic acid, hydrazine 2HCl. The first step was the reaction of removing carboxyl group and hydroxyl group and the second step was saponification of 3-(4-chlorobenzylidene)phthalide. The third step was the nucleophilic addition reactions of primary amines and the fourth step was addition reaction of N-methyl-1-aza-bicyclo[3,2,0]heptane to 4-(4-chlorobenzyl)-1-(2H)phthalazinone. As a result, product was analyzed by FT-IR and $^1H$-NMR and could be obtained with a yield of 80%.

• Journal of the Korean Applied Science and Technology
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• v.29 no.2
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• pp.317-322
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• 2012

The microstructures were examined by SEM, FT-IR spectra, tensible properties mole % of [NCO/OH], and particle size analyzer. Growing concerns in the environment-friendly industries have led to the development of solvent-free formulations that can be cured. We had synthesized the polyurethane resin having the ability to protect stainless steel against corrosion. Compared with general packing materials and coatings, this resin is highly stronger in intensity and longer durability. Polyurethane resins were composed of polyols, IPDI, silicone surfactant, catalyst and crosslink agent. Moreover, thermal fillers such as $Al_2O_3$, fume silica and $ZrO_2$ not only accelerated the curing rate but also improved the physical property as thermal barriers. The rigid segments of polyurethane in mechanical properties were due to crosslink agent and the increase of [NCO/OH]. In conclusion, the polyurethane microstructure with crosslink agent can be good material for themoset coating of metal substrates such as stainless steel.

• Korean Journal of Food Science and Technology
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• v.31 no.4
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• pp.1120-1123
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• 1999

The isolation of taurine from cooking wastes of anchovy factory ship was conducted. Anchovy cooking wastes had 93.9% moisture, followed by 4.8% ash, 0.4% protein and 0.2% lipid in order. Free amino acids of anchovy cooking wastes consisted of 38.8% taurine, 26.6% histidine and 10.0% glutamic acid. Taurine-rich fraction was isolated by cation and anion exchange chromatography with its yield and purity being 79.2% and 89.9%, respectively. The 80% ethanol precipitate obtained from the taurine-rich fraction showed yield of 29.5% and purity of 98.1% as taurine.

• Applied Chemistry for Engineering
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• v.18 no.2
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• pp.116-120
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• 2007

The synthesis of 1-[2-(3-{7-oxabicyclo[4.1.0]heptyl} 1,1,3,3-tetramethyl-disiloxane (Mono), which is a key intermediate for the synthesis of monomers applied for photopolymer systems based on the cationic ring opening polymerization, was studied. Mono was successfully synthesized by the hydrosilylation reaction of 4-vinyl-1-cyclohexene 1,2-epoxide (VCHO) with an excess amount of 1,1,3,3-tetramethyldisiloxane (TMDS) in the presence of a Speier catalyst. The structure and the purity of Mono were characterized by FT-IR, $^1H-NMR$, and $^{29}Si-NMR$. The optimum conditions for the hydrosilyation reaction were found to be 1:4 molar ratio of VCHO to TMDS and 5 ppm of the catalyst at the temperature of $55^{\circ}C$.