• Title/Summary/Keyword: IP-R&D

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Regulation of Atrial $Ca^{2+}$ Signaling by Inositol 1,4,5-Trisphosphate Receptor and Mitochondria (이노시톨 삼인산 수용체와 미토콘드리아에 의한 심방 근세포 $Ca^{2+}$ 신호전달의 조절)

  • Lee , Hyang-Jin;Cleemann , Lars;Morad , Martin;Woo, Sun-Hee
    • YAKHAK HOEJI
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    • v.48 no.6
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    • pp.352-357
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    • 2004
  • Atrial myocytes have two functionally separate groups of ryanodine receptors (RyRs): those at the periphery colocalized with L-type $Ca^{2+}$channels (DHPRS) and those a t the cell interior not associated with DHPRs. $Ca^{2+}$ current ($I_{ca}$) directly gates peripheral RyRs on action potential and the subsequent peripheral $Ca^{2+}$ release propagates into the center of atrial myocytes. The mechanisms that regulate the $Ca^{2+}$+ propagation wave remain Poorly understood. Using 2-D confocal$Ca^{2+}$ imaging, we examined the role of inositol 1,4,5-trisphosphate receptor (IP $_3R$) and mitochondria on ($I_{ca}$)- gated local $Ca^{2+}$ signaling in rat atrial myocytes. Blockade of IP $_3R$ by xestospongin C (XeC) partially suppressed the magnitudes of I ca-gated central and peripheral $Ca^{2+}$ releases with no effect on $I_{ca}$. Mitochondrial staining revealed that mitochondria were aligned with ${\thickapprox}2-{\mu}m$ separations in the entire cytoplasm of ventricular and atrial myocytes. Membrane depolarization induced rapid mitochondrial $Ca^{2+}$ rise and decay in the cell periphery with slower rise in the center, suggesting that mitochondria may immediately uptake cytosolic $Ca^{2+}$, released from the peripheral SR on depolarization, and re-release the $Ca^{2+}$ into the cytosol to activate neighboring central RyRs. Our data suggest that the activation of IP $_3R$ and mitochondrial $Ca^{2+}$ handing on action potential may serve as a cofactor for the $Ca^{2+}$ propagation from the DHPR-coupled RyRs to the DHPR-uncoupled RyRs with large gaps between them.

QuTFTP: Quick UDP Trivial File Transfer Protocol (QuTFTP: UDP 기반의 빠른 파일전송)

  • Kim, Byoung-Kug
    • Journal of Advanced Navigation Technology
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    • v.24 no.5
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    • pp.438-443
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    • 2020
  • To transfer files between nodes on network based on Ethernet, file transfer protocol (FTP) on TCP/IP and trivial file transfer protocol (TFTP) on UDP/IP are mostly used. Due to the lack of resources (processor, memory and so on) in the embedded system where we generally use for simple works with small firmware like ones; many of the systems implement only UDP/IP for their network stacks. Thus, TFTP is greatly to be preferred. For examples, environmental sensor devices for sensor networks, Boot Loader for general embedded device and preboot execution environment (PXE) boot for PC provide the TFTP. The logic of TFTP is simple for file transmission but, there is Stop-And-Wait problem during the process which occurs long blocking time. In this paper, we propose an algorithm which called QuTFTP(Quick UDP Trivial File Transfer Protocol) to reduce the length of the blocking time and to be compatible with the legacy TFTP.

Toll-like Receptor3-mediated Induction of Chemokines in Salivary Epithelial Cells

  • Li, Jingchao;Jeong, Mi-Young;Bae, Ji-Hyun;Shin, Yong-Hwan;Jin, Meihong;Hang, Sung-Min;Lee, Jeong-Chai;Lee, Sung-Joong;Park, Kyung-Pyo
    • The Korean Journal of Physiology and Pharmacology
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    • v.14 no.4
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    • pp.235-240
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    • 2010
  • Toll-like receptors (TLRs) functionally expressed in salivary epithelial cells, but their roles remain elusive. Among TLRs family, TLR3 is activated by dsRNA, a byproduct of viral infection. The aim of this study was to investigate the role of TLR3 in the inflammatory immune responses using HSG cells. Reverse transcriptase-polymerase chain reaction (RT-PCR), real-time PCR and ELISA were performed to identify expression of TLRs and TLR3-mediated chemokine inductions. The chemotaxis assay of activated T lymphocytes was also performed. Treatment of HSG cells with polyinosinic: polycytidylic acid (poly(I:C)) significantly increased interferon-$\gamma$-inducible protein 10 (IP-10), interferoninducible T-cell $\alpha$ chemoattractant (I-TAC), and regulated on activation, normal T-cells expressed and secreted (RANTES) gene expressions in a concentration-dependent manner. Anti-TLR3 antibody blocked the increases of IP-10 and I-TAC genes. Poly(I:C)-induced increases of IP-10 and I-TAC were also confirmed at protein levels from cell lysates, but their release into extracellular medium was detected only in IP-10. We found that the culture media from HSG cells stimulated with poly(I:C) significantly increases T lymphocyte migration. Our results suggest that TLR3 plays an important role in chemokine induction, particularly IP-10, in salivary epithelial cells.

Design and Performance Analysis of EU Directory Service (ENUM 디렉터리 서비스 설계 및 성능 평가)

  • 이혜원;윤미연;신용태;신성우;송관우
    • Journal of KIISE:Information Networking
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    • v.30 no.4
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    • pp.559-571
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    • 2003
  • ENUM(tElephon NUmbering Mapping) is protocol that brings convergence between PSTN Networks and IP Networks using a unique worldwide E.164 telephone number as an identifier between different communication infrastructure. The mechanism provides a bridge between two completely different environments with E.164 number; IP based application services used in PSTN networks, and PSTN based application services used in IP networks. We propose a new way to organize and handle ENUM Tier 2 name servers to improve performance at the name resolution process in ENUM based application service. We build an ENUM based network model when NAPTR(Naming Authority PoinTeR) resource record is registered and managed by area code at the initial registration step. ENUM promises convenience and flexibility to both PSTN and IP users, yet there is no evidence how much patience is required when users decide to use ENUM instead of non-ENUM based applications. We have estimated ENUM response time, and proved how to improve performance up to 3 times when resources are managed by the proposed mechanism. The proposition of this thesis favorably influences users and helps to establish the policy for Tier 2 name server management.

Robust Symbol Timing Recovery for Telephone tine Modems

  • Hwang, Sung-Hyun;Park, Hyun-Cheol k;Park, Hyung-Jin
    • Proceedings of the IEEK Conference
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    • 2002.07c
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    • pp.1819-1822
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    • 2002
  • The authors propose a robust symbol timing recovery (STR) for telephone line modems supporting data rates up to 32 Mbps. The STR is initialized by a start signal from carrier sensor, and the novel method is proposed which resolves the difference between the frequency of the transmitter's clock and the receiver's clock, called baud frequency offset. The proposed method is applied on digital receiver in a 16 frequency diverse quadrature amplitude modulation (FDQAM) system.

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Construction and Operation Analysis of Central Monitoring System for Photovoltaic System (태양광 발전 시스템을 위한 원격 통합 모니터링 시스템의 구축 및 운영 분석)

  • Shim, Hun;Lee, Yong-Ho;Kim, Jin-O;Kim, Jae-Eon
    • Proceedings of the KIEE Conference
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    • 2005.07b
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    • pp.1765-1767
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    • 2005
  • This paper proposes central monitoring system(PVCMS) based on a TCP/IP network for effective integrating management about photovoltaic systems. We don't gain confidence the result of production simulation, because the output of PV system have many various environmental change factor. So if we can obtain real operated data about each sites and system types to use PVCMS, we can define the environment change factor to compare with simulation data. And this paper try to access about total management and data analysis methods of renewable energy through results analysis to synthesize of the operation.

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Performance Evaluation of iSER on Storage system using Infiniband fabric (인피니밴드기반 저장장치에서의 iSER(iSCSI Extension for RDMA) 성능평가)

  • Kim, Young Hwan;Son, Jae-Gi;Jung, Hye-Dong
    • Proceedings of the Korea Information Processing Society Conference
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    • 2013.05a
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    • pp.148-150
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    • 2013
  • 최근 TCP/IP에서 세션을 통하여 노드들 간의 통신을 연결하는 방식에서 현재는 하나의 채널을 통해 고속의 I/O가 가능하도록 하는 인피니밴드 같은 기술이 많이 연구되고 있다. 인피니밴드는 프로세싱 노드와 입출력 장치 사이의 통신, 프로세스간 통신에 대한 산업 표준이 되고 있고 프로세싱 노드와 입출력 장치를 연결하기 위해 스위치 기반의 상호 연결은 전통적인 버스 입출력을 대체하는 새로운 입출력 방식이다. 또한 인피니밴드에서는 현재 이슈가 되고 있는 RDMA 방식을 이용해 원격지 서버들간에 직접 메모리 접근 방식을 통해 CPU와 OS의 로드를 최소화하고 있다. 본 논문에서는 인피니밴드 네트워크를 이용하는 저장장치 접근 프로토콜인 iSER(iSCSI Extension RDMA Protocol)와 기존 이더넷망에서 사용되는 iSCSI(Internet SCSI) 프로토콜을 이용하여 서버와 저장장치 간의 IOPS 와 초당 데이터 전송량에 대한 성능을 평가한다. 우리는 성능평가를 위해 Intel에서 제공하는 저장장치 I/O 성능평가 도구인 IO meter를 이용했다.

Full digital control of permanent magnet AC servo motors

  • Lee, Jin-Won;Kim, Dong-Il;Jin, Sang-Hyun;Oh, In-Hwan;Kim, Sungkwun
    • 제어로봇시스템학회:학술대회논문집
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    • 1993.10b
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    • pp.218-223
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    • 1993
  • In this paper, we present a full digital control scheme which controls currents and speed of the permanent magnet AC servo motor with large range of bandwidth and high performance. The current equations of the permanent magnet AC servo motor are linearized by feedback linearization technique. Both acceleration feedforward terms and IP controllers, whose gains are functions of motor speed, are used in order to control motor currents. In addition the phase delays in current control loops are compensated by placing phase lead-lag compensators after current commands, which make it possible to avoid high gains in the current controllers. Unity power factor can be achieved by the proposed current controller. Pulsewidth modulation is performed by way of the well-known comparison with a triangular carrier signals. The velocity controller is designed on the basis of the linearized model of the permanent magnet AC servo motor by the proposed current controller. The performance of the entire control system is analyzed in the presence of uncertainty in the motor parameters. The proposed control scheme is implemented using the digital signal processor-based controller composed of an Analog Device ADSP 2111 and a NEC78310. The pulsewidth modulation (PWM) signals are generated through a custom IC, SAMSUNG-PWM1, which has the outputs of current controllers as input. The experimental results show that the permanent magnet AC servo motor can be always driven with high dynamic performance by the proposed full digital control scheme of motor speed and motor current.

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Real-Time Port Logistics Location Tracking System using IP-RFID (IP-RFID를 이용한 실시간 항만물류 위치 추적 시스템)

  • Park, Byung-Kwon;Park, Min-Sun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.22 no.11
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    • pp.1531-1537
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    • 2018
  • In maritime logistics, a large number of containers are transported to the destination through a port in the form of composite transportation such as ships, trucks, and railways. Logistics parties such as shipping companies and consignors prefer having the real-time information on the entry and exit of the logistics hubs of the freight. Particularly, a port is an important space that connects the maritime and inland areas. Hence, the interest about freight of the logistics party in port is high. This study describes tracking the location of freight by using GPS dynamically based on area type rather than point type. This presents dynamic information of location tracking when the freight enters, exits from, and passes through a certain port area. I suggest a real-time location of the container cargos tracking algorithm in port-entry, port-exit, and port inside using Active IP-RFID technology based on the location tracking algorithm of previous research.

Variable Cut-off Frequency and Variable Sample Rate Small-Area Multi-Channel Digital Filter for Telemetry System (텔레메트리 시스템을 위한 가변 컷 오프 주파수 및 가변 샘플 레이트 저면적 다채널 디지털 필터 설계)

  • Kim, Ho-keun;Kim, Jong-guk;Kim, Bok-ki;Lee, Nam-sik
    • Journal of Advanced Navigation Technology
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    • v.25 no.5
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    • pp.363-369
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    • 2021
  • In this paper, We propose variable cut-off frequency and variable sample rate small-area multi-channel digital filter for telemetry system. Proposed digital filter reduced hardware area by implementing filter banks that can variably use cut-off frequency and sample rate without additional filter banks for an arbitrary cut ratio. In addition, We propose the architecture in which sample rate can variably be selected according to the number of filters that pass through the multiplexer control. By using time division multiplexing (TDM) supported by the finite impulse response (FIR) intellectual property (IP) of Quartus, the proposed digital filter can greatly reduce digital signal processing (DSP) blocks from 80 to 1 compared without TDM. Proposed digital filter calculated order and coefficients using Kaiser window function in Matlab, and implemented using very high speed integrated circuits hardware descryption language (VHDL). After applying to the telemetry system, we confirmed that the proposed digital filter was operating through the experimental results in the test environment.