• 제어로봇시스템학회:학술대회논문집
• /
• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
• /
• pp.103-103
• /
• 2000

In this paper to cope with the reduction of products life-cycle as the variety of products along with the various demands of consumers, a virtual simulator is developed to make the changeover of manufacturing line efficient to embody a virtual simulation similar to a real manufacturing line. The developed virtual simulator can design a layout of a factory and make the time scheduling. Every factory has one simulator so that one product can be manufactured in the factories to use them as virtual factories. We suggest a scheme that heightens the agility to the diversity of manufacturing models by making the information of manufacturing lines and products models to be shared. The developed unit simulator can construct a proper virtual manufacturing line along with the required process of products using several kinds of operator and work cell. A user with the simulator can utilize an interface that makes one to manage the separate task process for each manu(acturing module, change operator components and work cells, and easily teach tasks of each task module. The developed simulator was made for users convenience by Microsoft Visual C++ 6.0 that can develop a program supplying graphic user interface environment and by OpenGL of the Silicon Graphics as a graphic library to embody 3D graphic environment. Also, we show that the simulator can be used efficiently for the agile manufacturing by the communication among the factories being linked by TCP/IP and a hybrid database system made by a hierarchical model and a relational model being developed to standardize the data information.

• 한국통신학회논문지
• /
• 제27권11C호
• /
• pp.1164-1170
• /
• 2002

ACE2000 MPLS시스템에서 MPLS 정합모듈은 ATM 정합모듈과 패킷 포워딩을 수행하는 HFMA(High performance Forwarding Engine and VC Merging board Assembly)모듈로 구성된다. MPLS 정합모듈에서 물리층으로 입력되는 셀은 HFMA의 송신 SAR칩(RSAR)에서 패킷으로 조립된 후 IP룩업 제어기에서 패킷 포워딩을 수행한다. 포워딩된 패킷은 ATM 계층으로 전달되기 위해 수신 SAR칩(TSAR)에서 셀로 다시 세그먼트된 후 ATM 셀 스위치로 전송하기 위해 ALMA(ATM Layer Module Assembly)로 전달된다. MPLS 정합모듈을 ATM 정합보듈로 이용할 때, ALMA는 직접 물리층 보드와 UTOPIA Leve12 인터페이스로 연결되며, 이때 ALMA는 Master Mode로 동작하게 된다 또한 MPLS 정합모듈에서 HFMA TSAR도 Master Mode로 동작하게 된다. 따라서 2개의 Master 모드 사이에서 인터페이스 역할을 수행할 수 있는 Slave 모드의 UTOPIA-L2 Controller가 요구된다. 본 논문에서는 Multi-Ports를 지원할 수 있는 UTOPIA-L2 Controller의 구조 및 셀 제어방법에 대해 고찰해본다.

• Molecules and Cells
• /
• 제42권12호
• /
• pp.869-883
• /
• 2019

Interleukin (IL)-15 is an essential immune-modulator with high potential for use in cancer treatment. Natural IL-15 has a low biological potency because of its short half-life and difficulties in mass-production. IL-15Rα, a member of the IL-15 receptor complex, is famous for its high affinity to IL-15 and its ability to lengthen the half-life of IL-15. We have double-transfected IL-15 and its truncated receptor IL-15Rα into CT26 colon cancer cells to target them for intracellular assembly. The secreted IL-15:IL-15Rα complexes were confirmed in ELISA and Co-IP experiments. IL-15:IL-15Rα secreting clones showed a higher anti-tumor effect than IL-15 secreting clones. Furthermore, we also evaluated the vaccine and therapeutic efficacy of the whole cancer-cell vaccine using mitomycin C (MMC)-treated IL-15:IL-15Rα secreting CT26 clones. Three sets of experiments were evaluated; (1) therapeutics, (2) vaccination, and (3) long-term protection. Wild-type CT26-bearing mice treated with a single dose of MMC-inactivated secreted IL-15:IL-15Rα clones prolonged survival compared to the control group. Survival of MMC-inactivated IL-15:IL-15Rα clone-vaccinated mice (without any further adjuvant) exceeded up to 100%. This protection effect even lasted for at least three months after the immunization. Secreted IL-15:IL-15Rα clones challenging trigger anti-tumor response via CD4⁺ T, CD8⁺ T, and natural killer (NK) cell-dependent cytotoxicity. Our result suggested that cell-based vaccine secreting IL-15:IL-15Rα, may offer the new tools for immunotherapy to treat cancer.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• 제8권4호
• /
• pp.1344-1367
• /
• 2014

Mobile traffic is increasing a masse because of the propagation of the Internet and the development of wireless mobile technology. Accordingly, the Network Local Mobility Management (NETLMM) working group [1] of the Internet Engineering Task Force (IETF) has standardized Proxy Mobile IPv6 (PMIPv6) [2] as a protocol for accomplishing the transmissibility of mobile terminals. PMIPv6 is a network-led IP-based mobility management protocol, which can control terminal mobility without depending on the type of access system or the capability of the terminal. By combining PMIPv6 and the mobility of Session Initiation Protocol (SIP), we can establish terminal mobility and session mobility through a more effective route. The mobility function can be improved and the overlap of function reduced as compared to that in the case of independent operation. PMIPv6 is appropriate for a non-real-time service using TCP, and SIP is appropriate for a real-time service using RTP/UDP. Thus, in the case of a terminal using both services, an effective mobility management is possible only by using PMIPv6 together with SIP. In order to manage mobility in this manner, researches on PMIPv6-SIP are in progress. In line with this trend, this paper suggests a new PMIPv6-SIP architecture where when a mobile terminal conducts a handover, a network-led handover while maintaining the session without the addition of a special function or middleware is possible along with effective performance evaluation through mathematical modeling by comparing the delay and the packet loss that occur during the handover to the Pure-SIP.

• 한국정보통신학회논문지
• /
• 제15권10호
• /
• pp.2209-2216
• /
• 2011

본 논문에서는 Magnachip $0.18{\mu}m$ 공정을 이용하여 PMIC용 32bit eFuse OTP IP를 설계하였다. eFuse 링크 아래에 N-Well을 두어 프로그램시 eFuse 링크와 p-기판의 VSS가 단락되는 문제점을 해결하였다. 그리고 디코딩된 WERP (WL Enable for Read or Program) 신호가 eFuse OTP 메모리로 바로 입력되는 경우 듀얼 포트 eFuse OTP 메모리 셀의 RWL (Read Word-Line)과 WWL (Write Word-Line)을 선택적으로 활성화해 주는 WL 구동회로를 제안하였다. 또한 BL 프리차징 회로에서 delay chain을 제거하여 제어회로의 레이아웃 면적을 줄였다. 메모리 테스트 장비를 이용하여 제작된 94개의 샘플 die를 측정한 결과 5.5V의 프로그램 전압에서 100%의 수율을 얻었다.

• 대한약침학회지
• /
• 제20권1호
• /
• pp.29-35
• /
• 2017

Objectives: Aging is an unconscious and gradual process that can lead to changes in biological systems. Induction of oxidative stress and apoptosis, hepatotoxicity and neurotoxicity are involved in the aging process. Regarding the antioxidant property of black seed oil, the aim of this study was to evaluate the anti-aging effect of Nigella sativa (N. sativa) oil on d-galactose-induced aging in mice. Methods: For induction of aging, D-galactose (500 mg/kg, subcoutaneously SC) was administrated to male mice for 42 days. Animals were treated with D-galactose alone or with b lack seed oil (0.1, 0.2, 0.5 mL/kg, intraperitoneally (ip)). Additionally, vitamin E (200 mg/kg) was used as a positive control. At the end of treatment, the malondialdehyde (MDA) and the glutathione (GSH) contents in brain and liver tissues were measured. Also, enzymes in serum, including aspartate aminotransferase (AST) and alanine amino transferase (ALT), were determined. The levels of the proteins Bax, Bcl2, caspase-3 (pro and cleaved) in brain and liver tissues were evaluated. Results: Administration of D-galactose (500 mg/kg, SC) for 42 days increased serum levels of ALT and AST, as well as the MDA content, in brain and liver tissues, but decreased the GSH content. Additionally, the levels of apoptotic proteins, including Bax, procaspase-3 and caspase-3 cleaved, were markedly increased. N. sativa oil (0.1 and 0.2 mL/kg) diminished the levels of the biochemical markers ALT and AST. Administration of black seed oil (0.1, 0.2 and 0.5 mL/kg) reduced lipid peroxidation and at doses 0.1 and 0.2 mL/kg significantly recovered the GSH content. The oil decreased Bax/Bcl2 levels and at 0.1 mL/kg down-regulated the expressions of caspase-3 (pro and cleaved) proteins in brain and liver tissues. Conclusion: Through its antioxidant and anti-apoptosis properties, black seed oil exhibited an anti-aging effect in a model of aging induced with D-galactose.

• 대한한의학원전학회지
• /
• 제13권1호
• /
• pp.233-252
• /
• 2000

The contents of Yuk Mee Jee Dae Ron(六微旨大論) are as follows. 1. The Yuk Mee Jee Dae Ron(六微旨大論) is one of the Wun Gi Chil Pean(運氣七篇) which are inserted in So Moon(素問) by Wang Bing(王氷) who compile the So Moon(素問) into 24 volume. Wun Gi Chil Pean(運氣七篇) are Chun Won Ki Dae Ron(天元紀大論), O Woon Heng Dae Ron(五運行大論), Yuk Mee Jee Dae Ron(六微旨大論), Gi kuoo Beun Dae Ron(氣交變大論), O Sang Jeong Dae Ron(五常政大論), Yuk Won Jeong KI Dae Ron(六元正紀大論), Gee Gean Yoo Dae Ron(至眞要大論). 2. It prescribe the Sa Chun(司天) Jae Chun(在泉) Jwa Gan Gi(左間氣) Woo Gan Gi(右間氣). 3. It prescribe the Pheo Gi(標氣) Bon Gi(本氣) Juoog Gi(中氣). 4. It prescribe the Youk BO(六步) and the Sheung Gi(承氣). 5. It prescribe the Hamg Hae Sheung Jae(亢害承制) which is feedback control system between each Yuk Gi(六氣). 6. It prescribe the Sae whae(歲會), the Chun Boo(天符) and the Tae Il Chun Boo(太一天符). 7. It prescribe the active time of Yuk gi(六氣) within a year and Sae gi Whae Dong(歲氣會同). 8. It prescribe the Gi Gieo(氣交) which human beings and all the creation are living on. 9. It prescribe the Bo(步) which are composed of Chun Gi(天氣) and Jee Gi(地氣). 10. It prescribe the Duk(德) Wha(化) Yooung(用) bean(變) which are created by quarrel of Yuk Gi(六氣). 11. It prescribe the outbreak of the Sa Gi(邪氣). 12. It prescribe the Sin Gi(神機) and Gi Rib(氣立). 13. It prescribe all the creations existence are up to the Seoung Gang Chul Ip(升降出入). Like the past, the Yuk Mee Jee Dae Ron(六微旨大論) is include very important concep of the medicine. So the study should be continued with minute attention.

• 한국ITS학회 논문지
• /
• 제8권3호
• /
• pp.91-99
• /
• 2009

초고속 인터넷 서비스와 이동 통신의 발달, 그리고 Mobile Device 보급의 증가는 유비쿼터스(Ubiquitous) 기술의 발전을 촉진시키는 계기가 되었다. 와이브로 (WiBro, Wireless Broadband Internet) 시스템은 이동 중에도 무선 랜 (Wireless LAN) 보다 넓은 서비스 지원 영역에서 고속의 멀티미디어 서비스를 제공 받을 수 있는 MBWA(Mobile Broadband Wireless Access)기술이며, IP 기반의 백본 망(Backbone Network)로 구성된다. 이와 같은 무선 이동 통신 환경에서는 와이브로 시스템의 Layer 2(MAC Layer, Medium Access Control Layer)에서의 이동성 지원 기술뿐만 아니라 Layer 3(Network Layer)에서의 이동성 지원 프로토콜이 필요하며, 사용자가 이동 중에도 원활한 서비스를 제공받기 위해서는 핸드오버(Handovcr)의 지연 시간을 최소화 시켜야 한다. 따라서 본 논문에서는 IPv4 기반의 와이브로 망에서의 핸드오버 지연 단축 기법을 제안한다. 제안된 방법을 이동 단말(MS, Mobile Station)이 수신하는 신호 강도의 예측 값을 바탕으로 크로스 레이어 (Cross-Layer)기반의 고속 핸드오버 기법 (Fast Handover Scheme)을 적용하며, 지수평활법 (Exponential Smoothing Method)을 사용하여 예측 값을 계산한다. 모의 실험을 통해 기존의 방법과 제안된 방법을 비교, 분석하여 핸드오버 지연 시간의 단축을 증명한다.

• 천문학논총
• /
• 제29권3호
• /
• pp.45-52
• /
• 2014

This paper describes the development of algorithm for direct data transmission between Raw VLBI Data Buffer (RVDB) and Huge Capacity Data Server (HCDS) operated in Korea-Japan Correlation Center (KJCC). The transmitted data is the VLBI observation data, which is recorded at each radio telescope site, and the data transmitting rate is varying from 1 Gbps, in usual case, upto 8 Gbps. The developed algorithm for data transmission enables the direct data transmission between RVDB and HCDS through 10 Gbps optical network using VLBI Data Interchange Format (VDIF). Proposed method adopts the conventional UDP/IP protocol, but in order to prevent the loss of data during data transmission, the packet error monitoring and data re-transmission functions are newly designed. The VDIF specification and VDIFCP (VDIF Control Protocol) are used for the direct data transmission between RVDB and HCDS. To validate the developed algorithm for data transmission, we conducted the data transmission from RVDB to HCDS, and compared to the transmitted data with the original data bit by bit. We confirmed that the transmitted data is identical to the original data without any loss and it has been recovered well even if there were some packet losses.

• 한국정보통신학회논문지
• /
• 제20권2호
• /
• pp.343-350
• /
• 2016

본 논문에서는 감염된 IP로부터 악성 공격을 감지하고 예방하기 위한 안전하고 효율적인 온칩버스를 기술한다. 대부분의 상호-연결 시스템(온칩버스)은 모든 데이터와 제어 신호가 밀접하게 연결되어있기 때문에 하드웨어 말웨어 공격에 취약하다. 본 논문에서 제안하는 보안 버스는 개선된 아비터, 어드레스 디코딩, 마스터와 슬레이브 인터페이스로 구성되며, AHB (Advanced High-performance Bus)와 APB(Advance Peripheral Bus)를 이용하여 설계되었다. 또한, 보안 버스는 매 전송마다 아비터가 마스터의 점유율을 확인하고 감염된 마스터와 슬레이브를 관리하는 알고리즘으로 구현하였다. 제안하는 하드웨어는 Xilinx ISE 14.7을 사용하여 설계하였으며, Virtex4 XC4VLX80 FPGA 디바이스가 장착된 HBE-SoC-IPD 테스트 보드를 사용하여 검증하였다. TSMC $0.13{\mu}m$ CMOS 표준 셀 라이브러리로 합성한 결과 약 39K개의 게이트로 구현되었으며 최대 동작주파수는 313MHz이다.