• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• v.1
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• pp.133-138
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• 2006

Singular value decomposition (SDV) approach is applied to the observability analysis of GPS/INS in this paper. A measure of observability for a subspace is introduced. It indicates the minimum size of perturbation in the information matrix that makes the subspace unobservable. It is shown that the measure has direct connections with observability of systems, error covariance, and singular structure of the information matrix. The observability measure given in this paper is applicable to the multi-input/multi-output time-varying systems. An example on the observability analysis of GPS/INS is given. The measure of observability is confirmed to be less sensitive to system model perturbation. It is also shown that the estimation error for the vertical component of gyro bias can be considered unobservable for small initial error covariance for a constant velocity horizontal motion.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.22 no.1
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• pp.53-62
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• 2004

This paper deals with a new approach to acquire the exterior orientation parameters based on GPS(Global Positioning System) in combination with IMU(Inertial Measuring Unit), which enables us to achieve the same accuracy with minimal ground control points comparing to the conventional photogrammetric method. To prove the possibility of practical use of GPS/INS photogrammetry, a survey flight was conducted loading with all necessary photographing systems. The observed data set by GPS/IMU were analyzed and verified :he accuracy performance of kinematic GPS, and also compared to those of conventional photogrammetry in various points of view.

• The Journal of Korea Robotics Society
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• v.10 no.1
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• pp.1-8
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• 2015

This paper proposes a study for accurate surface localization system using DWT(Discrete Wavelet Transform) and GPS/INS fusion algorithm. Because the propagation in the underwater is not passed by characteristics of the medium unlike the ground, the sonar system like DVL is used instead of GPS. But since these systems are installed on the seafloor and operated, a long time is required for installation and navigation systems are limited outside of the range area. And it is difficult to estimate position in a three-dimensional considering the depth in actual marine environment. In this paper, before the development of underwater localization system, precisely estimated position system is proposed in a two-dimensional by developing surface localization system using removing noise and disturbance with DWT and relatively inexpensive GPS and INS sensor.

• The Journal of the Korean life insurance medical association
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• v.3 no.1
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• pp.256-268
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• 1986

We'd experienced 172 cases of fatty liver among 3,713 cases, that was examined by ultrasonography at medical department, Dae Han Kyoyuk Ins. company for recent one year from november, 1984 to November, 1985. The conclusions are as follows; 1. The possessing rate of fatty liver is 4.63% in total caees 138/2234 male(6.18%), 34/2234 female(2.3%) and that in male is 2.7 times than female. 2. In the distribution of fatty liver for age, the group of $21{\sim}30$ years are 9/564 cases(1.6%), the group of $31{\sim}40$ years are 74/1777, the group of $41{\sim}50$ years are 59/976(6.05%),the group of $51{\sim}60$ years are 29/240(12.08%) with age, the possessing rate of fatty liver was increased. 3. For sex, age, the possessing rate of fatty liver, in male $21{\sim}30$ years 8/329 cases(2.43%), $31{\sim}40$ years 64/118(5.72%) $41{\sim}50$ years 43/618(6.96%), $51{\sim}60$ years 22/134(16.42%) and in female, $21{\sim}30$ years 1/335(0.3%), $31{\sim}40$ years 10/659(1.52%) $41{\sim}50$ years 16/358(4.47%), $51{\sim}60$ years 7/106(6.6%) and then in total sex, with age, the incidence was increased. 4. 172 cases in fatty liver, we could find 109 cases of obesity(63.37%), in female the rate was more. 5. The abnormal was 13.95% for the level of Fasting blood sugar of fatty liver 172 cases, the average level of blood sugar was high markedly in female, on the contrary the number of abnormal blood sugar level was high in male. 6. In liver function test of 172 cases of fatty liver, the abnormal of sGOT value was 18.6%, sGOT value 20.93%, average of abnormal group in sGOT value was 52.62 units, sGPT value 56.99 units.

• Molecules and Cells
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• v.20 no.3
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• pp.305-314
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• 2005

Investigation of chemically synthesized inositol 1,4,5-trisphosphate [$Ins(1,4,5)P_3$] analogs has led to the isolation of a novel binding protein with a molecular size of 130 kDa, characterized as a molecule with similar domain organization to phospholipase C-${\delta}1$ (PLC-${\delta}1$) but lacking the enzymatic activity. An isoform of the molecule was subsequently identified, and these molecules have been named PRIP (PLC-related, but catalytically inactive protein), with the two isoforms named PRIP-1 and -2. Regarding its ability to bind $Ins(1,4,5)P_3$ via the pleckstrin homology domain, the involvement of PRIP-1 in $Ins(1,4,5)P_3$-mediated $Ca^{2+}$ signaling was examined using COS-1 cells overexpressing PRIP-1 and cultured neurons prepared from PRIP-1 knock-out mice. Yeast two hybrid screening of a brain cDNA library using a unique N-terminus as bait identified GABARAP ($GABA_A$ receptor associated protein) and PP1 (protein phosphatase 1), which led us to examine the possible involvement of PRIP in $GABA_A$ receptor signaling. For this purpose PRIP knock-out mice were analyzed for $GABA_A$ receptor function in relation to the action of benzodiazepines from the electrophysiological and behavioral aspects. During the course of these experiments we found that PRIP also binds to the b-subunit of $GABA_A$ receptors and PP2A (protein phosphtase 2A). Here, we summarize how PRIP is involved in $Ins(1,4,5)P_3$-mediated $Ca^{2+}$ signaling and $GABA_A$ receptor signaling based on the characteristics of binding molecules.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.23 no.3
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• pp.323-330
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• 2005

More than ten years after the era of GPS-Photogrammetry which could provide us only three projection center of all six exterior orientation parameters, direct georeferencing with GPS/INS is now becoming a standard method for image orientation. Its main advantage is to skip or reduce the indirect ground control process. This paper describes the experimental test results of integrated sensor orientation with a commercial GPS/IMU system to approve its performance in determination of exterior orientation. For this purpose two different imaging blocks were planned and the area was photographed at a large photo scale of 1:5,000 and a medium photo scale of 1:20,000. From these data set a variety of meaningful results was acquired, i.e., the accuracy. potential of exterior orientation from direct georeferencing and combined block adjustment using these data considering different photo scales and conditions.

• Korean Journal of Medicinal Crop Science
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• v.11 no.1
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• pp.24-30
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• 2003

Aqueous extracts from eleven species of Korean medicinal plants were screened for antiviral activity against transmissble gastroenteritis virus (TGEV) and porcine epidemic diarrhae virus (PEDV). Seven of eleven plant extracts were found to have cytotoxicity for ST cells at the concentration of 1mg/ml, and ten extracts except Ephedra sinica were found to have non-cytotoxicity for Vero cells at the same concentration, Extracts of Zanthoxylum piperium, Cudrina tricuspidata, Clerodendron trichomum, Sophora flavescens, effectively inhibited TGEV, respectively. There were the antiviral activity against TGEV in the extracts of Glesdistsia sinensis, Euonymus alatus, Ficus carica, Solanum nigrum, Ephedra sinica, Xanthium strumarium, Acanthopanax seeliflorus in spite of their cytotoxicities. Nine extracts except Xanthium strumarium and Acanthopanax seeliflorus were found to have the antiviral activitity against PEDV. Extracts of Zanthoxylum piperium, Sophora flavescens was shown to have antiviral activities against both TGEV and PEDV.

• ETRI Journal
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• v.30 no.1
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• pp.59-67
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• 2008

The necessity for the precise time synchronization of measurement data from multiple sensors is widely recognized in the field of global positioning system/inertial navigation system (GPS/INS) integration. Having precise time synchronization is critical for achieving high data fusion performance. The limitations and advantages of various time synchronization scenarios and existing solutions are investigated in this paper. A criterion for evaluating synchronization accuracy requirements is derived on the basis of a comparison of the Kalman filter innovation series and the platform dynamics. An innovative time synchronization solution using a counter and two latching registers is proposed. The proposed solution has been implemented with off-the-shelf components and tested. The resolution and accuracy analysis shows that the proposed solution can achieve a time synchronization accuracy of 0.1 ms if INS can provide a hard-wired timing signal. A synchronization accuracy of 2 ms was achieved when the test system was used to synchronize a low-grade micro-electromechanical inertial measurement unit (IMU), which has only an RS-232 data output interface.

• Journal of Advanced Navigation Technology
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• v.21 no.1
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• pp.138-144
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• 2017

A method for improving the integrated navigation performance in the INS/GPS navigation system by the considering that the condition that the geometric arrangement of the satellite is degraded due to limitation of the line of sight of the satellite such as geographic feature and GPS signal jamming is proposed. A variable covariance extended Kalman filter (VCEKF) that correlated to the measured covariance to the DOP of GPS is suggested. The navigation performance of integrated navigation system using EKF and VCEKF is analyzed by Monte-Carlo simulations. The result is verified that VCEKF has better estimation performance than EKF using fixed covariance on condition that DOP value is larger than the smaller value.

• Journal of Life Science
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• v.31 no.4
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• pp.425-429
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• 2021

We have investigated the expression of early growth response protein 1 (EGR1) in INS-1 pancreatic β-cells treated with Allomyrina dichotoma hemolymph. The Korean rhinoceros beetle, A. dichotoma (Coleoptera: Scarabaeidae), is important in the insect industry for medical applications. We have already established a method for purification of A. dichotoma hemolymph that can be used in many experiments. EGR1 is reported as a multifunctional transcription factor that is implicated in virus infections. EGR1 has therefore been revealed as a major mediator and regulator in the physiological and pathological conditions of several cell and tissue types. New findings in this study are that A. dichotoma hemolymph, which promotes a dose- and time-dependent upregulation of EGR1 gene expression, shows an enhancement of this gene expression when combined with hypothermia or endoplasmic reticulum (ER) stress. These results suggest that A. dichotoma hemolymph may provide clues to EGR1-associated disease therapies involving gene regulation of EGR1.