• Title/Summary/Keyword: IDM

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Drug Release from Hollow Suppository(I) - Release Rate of Indomethacin from Witepsol H-15 Suppository - (중공 좌제의 약물방출 (I) - Witepsol H-15 기제로부터의 인도메타신의 방출속도 -)

  • 이화정;구영순
    • YAKHAK HOEJI
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    • v.35 no.3
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    • pp.197-202
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    • 1991
  • In order to study drug release from the suppository, three types of hollow suppositories and one conventional suppository were prepared using indomethacin(IDM) as a model drug and Witepsol H-15 as a base. The 4 types of suppository prepared are as follows: type I, conventional suppository containing 50 mg of IDM powder, type II, hollow supository containing 50 mg of IDM powder in the cavity, type III, hollow suppository containing 25 mg of IDM powder in the base and IDM microcapsules (25 mg as IDM powder) in the cavity, and type IV, hollow suppository containing IDM microcapsules (25 mg as IDM powder) in the base and 0.5 ml of 5%(w/v) IDM-PEG 300 solution in the cavity. The drug amount released(%) from type II and I within 24 hrs was 46.7% and 66.9%, respectively. Comparing with the drug amount released from four types of suppository within initial 2 hrs and 24 hrs, that of type IV was high as 32.7% and 76.6%, respectively. IDM-ethycellulose microcapsules passed through 270 mesh sieve and the IDM content was 20.95%.

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Development of IDM for BIM based Structural Steel Member Design (BIM 기반 철골부재 단면설계를 위한 IDM 개발)

  • Jung, Jong-Hyun;Lee, Jae-Cheol
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.2
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    • pp.1434-1440
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    • 2015
  • IDM is a methodology for capturing and specifying processes and information flow during the life-cycle of a facility. The methodology can be used to document existing or new processes, and describe the associated information that need to be exchanged between parties. In this paper, the information model for BIM-based structural steel member design was defined using IDM methodology. The structural information offered in IFC was analyzed, and its adequacy was verified by applying the case study using Excel. As a result, $IFC2{\times}3$ offers the most structural design information for BIM-based structural steel member design, and some sectional properties omitted in $IFC2{\times}3$ were offered in IFC4. IDM methodology can be used effectively for developing BIM-based structural design systems.

Comparison of Three Active-Frequency-Drift Islanding Detection Methods for Single-Phase Grid-Connected Inverters

  • Kan, Jia-rong;Jiang, Hui;Tang, Yu;Wu, Dong-chun;Wu, Yun-ya;Wu, Jiang
    • Journal of Power Electronics
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    • v.19 no.2
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    • pp.509-518
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    • 2019
  • A novel islanding detection method is proposed in this paper. It is based on a frequency drooping PLL, which was presented in a previous work. The cause of errors in the non-detection zone (NDZ) of conventional frequency disturbance islanding detection methods (IDM) is analyzed. A frequency drooping phase-locked-loop (FD-PLL) is introduced into a single-phase grid-connected inverter (SPGCI), which can guarantee that grid current is in phase with the grid voltage. A novel FD-PLL IDM is proposed by improving this PLL. In order to verify the performance of the proposed FD-PLL IDM, a full performance comparison between the proposed IDM and typical existing active frequency drift IDMs is carried out, which includes both dynamic performance and steady performance. With the same NDZ, the total harmonic distortion of the grid-current in the dynamic process and steady state is analyzed. The proposed FD-PLL IDM, regardless of the dynamic or steady process, has the best power quality. Experimental and simulation results verify that the proposed FD-PLL IDM has excellent performance.

Capturing Information Exchange Process among Structural Engineering Software Applications for BIM Deployment Using IDM (BIM 적용을 위한 구조설계 엔지니어링 소프트웨어 간 정보교환 프로세스 분석 및 표준문서화)

  • Kim, Jae-Woo;Lim, Jae-In;You, Seok-Joon;Kwon, Soon-Wook;Chin, Sang-Yoon;Choi, Cheol-Ho
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2008.04a
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    • pp.464-469
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    • 2008
  • Information Delivery Manual (IDM) is a documentation format for capturing the information requirements among various AEC project tasks and their software uses. The authors analyzed the structural engineering and analysis domain and were able to define its process model definition and the information flow required for the process by following the methodology stated in the IDM format. The authors believe that The manual has its potentials for further enhancements for IFC-based process integration by transferring it into a information model schema, which can be later referenced by the software applications to automatically determine which data need to be exchanged.

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A Study on IDM Development for Automation of BIM-based Architectural Facade Design - Focused on Musical Proportion - (BIM기반 건축 파사드 디자인 자동화를 위한 IDM 개발에 관한 연구 - 음계비례를 중심으로 -)

  • Heo, Kyu-Souk;Choo, Seung-Yeon
    • Korean Journal of Computational Design and Engineering
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    • v.15 no.5
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    • pp.393-402
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    • 2010
  • Existing construction industry is composed of several processes with various characteristics. The tendency of current construction industry is getting complicated and diversified; it has limitation to solve problems through existing processes. As a problem-solving method, BIM (Building Information Modeling), environment to manage building life cycle from design and construction to management, is being suggested. Currently, BIM is only focused on technology development by engineers, and the automation of architectural theories is insufficiency except architectural design modeling. Therefore, this research aims to back up theses drawbacks through intellectual curtain wall arrangement by using musical proportions. In order to apply to construction automation, analysised of musical proportions method are performed. The BPMN-based Process Map is listed to develop IDM for the application to BIM Software.

종이 문서가 진정 문제인가? 문서 관리(DM) vs. ECM

  • JePeu, Pil-Rip
    • Digital Contents
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    • no.11 s.126
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    • pp.160-166
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    • 2003
  • 모든 조직들이 엔터프라이즈 콘텐츠 매니지먼트(ECM)가 필요한 것은 아니다. 도큐랩스(Doculabs)는 통합문서관리(IDM)의 개요와 각종 비즈니스 문제들을 해결할 때의 IDM의 역할에 대해 재조명해본다.

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Controlled Release of Propranolol Hydrochloride and Indomethacin from Hollow Type Suppository Using Witepsol H-15 (Witepsol 중공좌제로부터의 염산프로프라놀롤 및 인도메타신의 방출제어)

  • Jin, Suk-Yeong;Gu, Yeong-Sun
    • YAKHAK HOEJI
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    • v.40 no.4
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    • pp.400-410
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    • 1996
  • In oder to develop the controlled release of drugs from the suppositories, in vitro drug release and in vivo absorption in rabbits were investigated. Various suppo sitory forms with hollow cavities, into which drugs in the form of fine powder or solid dispersion system(SDS) could be placed, were utilized. The oleaginous Witepsol H-15 (WH-15) as a base, and indomethacin (IDM) of a very slightly soluble drug and propranolol-HCL (PPH) of a very soluble drug were employed as model drugs. The in vitro drug release showed that the cumulative release amount of PPH from PPH-(methylcellulose) MC-SDS and PPH-(ethylcellulose) EC-SDS hollow type suppositories reached 40% and 12% in 6 hrs,respectively. On the other hand, the drug release for a conventional suppository was 80% in 6 hrs. For the IDM suppositories,the cumulative drug release from IDM-(polyvinylpyrrolidone) PVP-SDS hollow type suppositories reached 99% in 24 hrs, whereas that from a conventional suppository reached 85%. An in vivo experiment with rabbits showed that IDM-PVP-SDS hollow type suppository delayed the absorption of IDM, significantly. The $t_{max},\;C_{max}\;and\;AUC_{0{\to}8}$ of IDM-PVP-SDS suppository were 60 min, 12.12${\mu}g$/ml and 2657${\mu}g$/ml/min, respectively. The $t_{max},\;C_{max}\;and\;AUC_{0{\to}8}$ of controlled group were 20 min, 15.49${\mu}g$/ml and 2190${\mu}g$/ml/min, respectively.

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Information Delivery Requirements of Steel Structure according the Structural Design Stages using IDM (IDM을 이용한 강구조의 구조설계 단계별 정보전달 요구 분석)

  • Lee, Jae-Cheol
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.3
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    • pp.1467-1473
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    • 2013
  • In construction project, it is important to exchange and share the digital information generated by their own professional softwares. So this paper analyzed the information delivery requirements of steel structure according the structural design stages using IDM methodology. For schematic design stage and detailed design stage, the structural design information to share in each design stages is abstracted by defining the PM, ER, and FP. The new ERs and FPs are proposed by defining the new property sets(Psets), suchlike bolt gauge line, weld, scallop, and cope, to complement the structural design information of $IFC2{\times}3$. Finally, the reasonability of the proposed new ERs, FPs are verified by applying them to represent the standard steel connection sample in detailed design stage. As a result, the structural design information of standard steel connection could be stored and managed sufficiently by using the proposed new ERs and FPs.

Analysis of Effects of Autonomous Vehicle Market Share Changes on Expressway Traffic Flow Using IDM (IDM을 이용한 자율주행자동차 시장점유율 변화가 고속도로 교통류에 미치는 영향 분석)

  • Ko, Woori;Park, Sangmin;So, Jaehyun(Jason);Yun, Ilsoo
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.20 no.4
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    • pp.13-27
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    • 2021
  • In this study, the impact of traffic flow on the market penetration rate of autonomous vehicles(AV) was analyzed using the data for the year 2020 of the Yongin IC~Yangji IC section of Yeongdong Expressway. For this analysis, a microscopic traffic simulation model VISSIM was utilized. To construct the longitudinal control of the AV, the Intelligent Driver Model(IDM) was built and applied, and the driving behavior was verified by comparison with a normal vehicle. An examination of the study results of mobility and safety according to the market penetration rate of the AV, showed that the network's mobility improves as the market penetration rate increases. However, from the point of view of safety, the network becomes unstable when normal vehicles and AVs are mixed, so there should be a focus on traffic management for ensuring safety in mixed traffic situations.

Self-Sovereign Identity Management: A Comparative Study and Technical Enhancements

  • Noot A. Alissa;Waleed A. Alrodhan
    • International Journal of Computer Science & Network Security
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    • v.23 no.12
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    • pp.27-80
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    • 2023
  • Nowadays usage of different applications of identity management IDM demands prime attention to clarify which is more efficient regarding preserve privacy as well as security to perform different operations concerning digital identity. Those operations represent the available interactions with identity during its lifecycle in the digital world e.g., create, update, delete, verify and so on. With the rapid growth in technology, this field has been evolving with a number of IDM models being proposed to ensure that identity lifecycle and face some significant issues. However, the control and ownership of data remines in the hand of identity service providers for central and federated approaches unlike in the self-sovereign identity management SSIM approach. SSIM is the recent IDM model were introduced to solve the issue regarding ownership of identity and storing the associated data of it. Thus, SSIM aims to grant the individual's ability to govern their identities without intervening administrative authorities or approval of any authority. Recently, we noticed that numerous IDM solutions enable individuals to own and control their identities in order to adapt with SSIM model. Therefore, we intend to make comparative study as much of these solutions that have proper technical documentation, reports, or whitepapers as well as provide an overview of IDM models. We will point out the existing research gaps and how this study will bridge it. Finally, the study will propose a technical enhancement, everKEY solution, to address some significant drawbacks in current SSIM solutions.