• Journal of the Korea Institute of Information and Communication Engineering
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• v.9 no.4
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• pp.824-831
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• 2005

Past corporaion's network security system is single security solution, or mixed several ways, but there was inefficient system because doing not get into organic link But, constructed more strong security system by ESM enterance on. ESM uses way to integrate of each agent to manage easily various kinds security solution. That is, it is system that connect system of existent VPN, FireWall, IDS and so on configurationally depending on security policy and manage. ESM is security system that is developed more than existent security system. But, practical use of network and the development speed of technology being increasing with the mon faster speed, is heightening the level more as well as dysfunction of information crime and so on. Many improvements are required at ESM system, this research wished to make up for the weak-point in the ESM system about interior security. Studied on structure of security solution that is basis of security policy. VPN, Firewall, IDS's link that is main composition of existing security system analysis, reconstructed. And supplemented security of ESM system itself. Establish imaginary intrusion and comparative analysis access data that apply each Telnet Log analysys IDS existent ESM system and proposed ESM system comparative analysis. Confirm the importance of interior security and inspected security of proposed system.

• Journal of the Korea Organic Resources Recycling Association
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• v.4 no.2
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• pp.35-45
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• 1996

In order to investigate the possibility of treating nightsoil sludge, the growth trend experiments with vermicompsting was performed and the stability of worm castings was evaluated by the analysis of minerals according to growth periods. Survival rate(SR) of earthworms decreased as earthworms grow up to 7 weeks. The growth period of the earthworms could be classified into two phases on the basis of the ratios of cast to feed ingested(ID). The growth period of the earthworms up to 3 weeks, the high percentage of dry weight of feed ingested(ID) is mainly utiliz-ed to an increase in fresh weight of earthworms, and after the 3 weeks, it is utilized to cast production in this experiment, respectively. The highest values of increasing rate(IR) and biomass of the earthworms(BE) were obtained at 3 weeks and those were 10.59mg/day and 14.48g, respectively. Between the increasing rate(IR) and biomass of the earthworms(BE), a highly positive correlation coefficient(p<0.001) ap-peared. The highest values of biomass of the earthworms(BE) and cast production(CW) were obtained at 3 and 7 weeks, respectively. All the concentrations of minerals except calcium(Ca) in worm castings was lower than the values in nightsoil sludge. It was considered that the major portion of minerals in nightsoil sludge may have been retained in the bodies of earthworms. And these values were lower than the regulated levels in organic fertilizers that the regula-tion standards. In conclusion, the worm castings are very stable for the use as soil conditioner or organic fertilizers.

• Korean Journal of Microbiology
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• v.40 no.4
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• pp.348-354
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• 2004

The expression and antibacterial. activity of recombinant human lactoferrin (hLf) was studied from meth­ylotrophic yeast Pichia pastoris. The gene encoding hLf, isolated from human breast cDNA library, was subcloned into the expression vector, pPIC3.5K under the control of AOX1 promoter. The gene was integrated into the host chromosome and was identified by Southern blotting. The expression of the integrated gene was investigated by RT-PCR, Northern blotting, SDS-PAGE and Western blotting. Discrete band corresponding to hLf was detected from the SDS-PAGE, which was confirmed by Western blotting. The expression was also confirmed by RT-PCR and Northern blotting. The antibacterial activity of the recombinant hLf (rhLf) was investigated using Staphy­lococcus aureus ATCC 6538P and Micrococcus flavus ATCC 10240 as test organisms. The rhLf showed strong antibacterial activities against the bacteria. Furthermore, many Gram-negative animal pathogens such as E.coli ATCC8739, 25922, and Salmonella typhimurium 114 and 115, Pseudomonas fluorescens ID 963 I, P. aeruginosa KCCM 11802, and Gram-positive bacteria Bacillus mesentericus were also inhibited in their growth by the rhLf.

• Korean Journal of Microbiology
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• v.39 no.4
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• pp.207-215
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• 2003

Gene structure prediction, which is to predict protein coding regions in a given nucleotide sequence, is the most important process in annotating genes and greatly affects gene analysis and genome annotation. As eukaryotic genes have more complicated stuructures in DNA sequences than those of prokaryotic genes, analysis programs for eukaryotic gene structure prediction have more diverse and more complicated computational models. We have developed EGSP, a eukaryotic gene structure program, using duration hidden markov model. The program consists of two major processes, one of which is a training process to produce parameter values from training data sets and the other of which is to predict protein coding regions based on the parameter values. The program predicts multiple genes rather than a single gene from a DNA sequence. A few computational models were implemented to detect signal pattern and their scanning efficiency was tested. Prediction performance was calculated and was compared with those of a few commonly used programs, GenScan, GeneID and Morgan based on a few criteria. The results show that the program can be practically used as a stand-alone program and a module in a system. For gene prediction of eukaryotic microbial genomes, training and prediction analysis was done with Saccharomyces chromosomes and the result shows the program is currently practically applicable to real eukaryotic microbial genomes.

• Journal of Oral Medicine and Pain
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• v.26 no.1
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• pp.39-50
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• 2001

In order to investigate the effect of Transforming growth factor ${\beta}1$(below TGF-${\beta}1$) and osteogenic protein-1(below Op-1) onto the myogenic differentiation, C2C12 satellite myoblastic cell line was cultured and treated with both growth factors. At first morphological changes with microscopical examination were examined, and isolated total RNA to analyse mRNA expression of bone marker proteins, muscle regulatory proteins, TGF-${\beta}$ receptor and their ligands by Northern blot analysis. And cellular proliferative inducibility of both growth factors was also tested to C2C12 cells. Incubating the cell with $5ng/m{\ell}$ of TGF-${\beta}1$ until 4 days almost inhibited multinucleated myotube formation expressing muscular regulatory proteins, and induced decreasing Id proteins. However, no osteoblastic phenotypes was induced by TGF-${\beta}1$ in C2C12 cells. The mRNA expression of TGF-${\beta}$ receptors with TGF-${\beta}1$ was conversed after 48 hours cultured. Type I TGF-${\beta}$ receptor was seemed to play a role in negative signalling for inhibition of myogenic differentiation. OP-1 dose dependently induced ALP activity, osteopontine production and bone sialoprotein production at concentrations above $100ng/m{\ell}$ and osteocalcin production at concentrations above $300ng/m{\ell}$. The concentration of OP-1 required to induce these osteoblastic phenotypes was the same as that required to almost completely inhibit myotube formation. Incubation with above $100ng/m{\ell}$ OP-1 suppressed the expression of mRNA for muscular egulatory proteins from 2 days after incubation. Expression of Id-1, 2, 3 mRNA were stimulated by OP-1 at concentration above $300ng/m{\ell}$. When C2C12 cells were treated with both growth factors, TGF-${\beta}1$ potentiated the inhibitory effect of OP-1 on myotube formation and expression of mRNA for myogenin at 12 days. And TGF-${\beta}1$ reduced osteocalcin and bone sialoprotein production induced by OP-1 at 12 days in C2C12 cells. Both growth factor had no mitogenic effect. These results indicate that OP-1 converts the differentiation pathway of C2C12 myoblasts into that of osteoblastic lineage cells and it's not heritable, but TGF-${\beta}1$ does not and has reversible inhibitory activity on the myogenic differentiation. TGF-${\beta}1$ and OP-1 play a role in myogenic differentiation via different mechanism between them.

• Journal of the Korean Magnetics Society
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• v.25 no.1
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• pp.4-9
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• 2015

This study was carried out to investigate a influence of humidity variation (%) on the magnetic properties and the surface flaws in the fabrication of Fe-based $Fe_{78}Si_9B_{13}$ amorphous alloy ribbon by Planar Flow Casting process. As a result, the size of the air pocket and the droplet which is observed in the contact surface and the free face of the amorphous alloy ribbon becomes large when the humidity increases and the size highly increases with the surface roughness at the same time. Especially, the surface roughness value which is made in the 65 % of the humidity is the lowest in the contact surface ($Ra=0.60{\mu}m$, $Rz=3.11{\mu}m$) and the free face ($Ra=0.47{\mu}m$, $Rz=3.00{\mu}m$). Also, in case of the soft magnetic property of the magnetic core which is made with the toroidal core of $23(OD)^*20(ID)^*20(H)$ size, in the sample of the amorphous alloy ribbon which is made in 65% of the humidity, the most excellent value is gained as $B_s(B_{700})=1.055T$, $H_c=0.083Oe$, permeability = 1,197 and core loss = 0.276W/kg.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.43 no.4 s.310
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• pp.46-54
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• 2006

Recently, the important of a personal identification is increasing according to expansion using each on-line commercial transaction and personal ID-card. Although a personal ID-card embedded RFID(Radio Frequency Identification) tag is gradually increased, the way for a person's identification is deficiency. So we need automatic methods. Because RFID tag is vary small storage capacity of memory, it needs effective feature extraction method to store personal biometrics information. We need new recognition method to compare each feature. In this paper, we studied the face verification system using Hippocampal neuron modeling algorithm which can remodel the hippocampal neuron as a principle of a man's brain in engineering, then it can learn the feature vector of the face images very fast. and construct the optimized feature each image. The system is composed of two parts mainly. One is feature extraction using NMF(Non-negative Matrix Factorization) and LDA(Linear Discriminants Analysis) mixture algorithm and the other is hippocampal neuron modeling and recognition simulation experiments confirm the each recognition rate, that are face changes, pose changes and low-level quality image. The results of experiments, we can compare a feature extraction and learning method proposed in this paper of any other methods, and we can confirm that the proposed method is superior to the existing method.

• The Korean Journal of Pharmacology
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• v.22 no.2
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• pp.88-95
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• 1986

Clinically, subhypnotic doses of barbiturates have been known to elicit hyperalgesia. In this experiment, effect of acute or chronic phenobarital treatment on the response to pain in rat was reevaluated by hot-plate method. To elucidate its mechanism, changes of ${\beta}-endorphin$ contents and [3H]-morphine binding of the rat midbrain as well as functional opiate receptor in vas deferens were also measured. Intraperitoneal injection of sub anesthetic dose phenobarbital induced initial hyperalgesia followed by successive analgesia, while chronic phenobarbital-treatment decreased reactivity to pain. Naloxone (10mg/kg, i.p.) markedly shortened hot plate latency period, and significantly inhibited the analgesic action of phenobarbital. Single dose of phenobarbital did not affect ${\beta}-endorphin$ contents and [3H]-morphine binding in rat mid brain, but in the chronic phenobarbital-treated groups, ${\beta}-endorphin$ contents was increased, while Bmax of opiate receptor binding was decreased. Moreover, very significant correlations among responses to pain, changes of ${\beta}-endorphin$ contents and opiate receptor binding were observed. However, Kd values of opiate receptor bindings were not changed in all preparations. In the chronic phenobarbital-treated vas deferens preparations, ID50 of morphine was increased witb concomittant decrease of maximum effect. But $pA_2 $, value for naloxone was not changed. From these results, it is suggested that phenobarbital can produce analgesia due to changes of ${\beta}-endorphin$ contents as well as functional opiate receptors by receptor regulation.

• Journal of Music and Human Behavior
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• v.18 no.2
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• pp.45-66
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• 2021

This study aimed to develop a group rap making program and examine its applicability to improve communication skills of adolescents with mild intellectual disabilities (ID). Three adolescents with ID participated in a total of six 50-minute group sessions over 4 weeks. The group rap making program included three stages: understanding the context of communication, learning how to communicate with others, and applying the communicative behaviors in a group setting. To examine changes in the participants' communication skills, the rap lyrics constructed by participants were analyzed and communicative behaviors were observed during sessions and analyzed in terms of asking questions and providing information to others. Also, a social communication skills checklist was rated by the participant's caregivers. The analysis of rap lyrics showed that the expressions included in the rap were diversified as the session proceeded. Changes in observed behaviors supported that participants became to engage in communication with others more actively in order to complete the group rap. While the social communication skills checklist tended to increase, there was a difference in degree of change depending on the level of language communication skills. These results indicate that a group rap making can be an effective option for these adolescents to learn how to communicate with their peers, which presents implications for how rap making can be used for therapeutic purpose with more diversified population.

• Journal of the Korean Institute of Gas
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• v.25 no.5
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• pp.78-87
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• 2021

This paper analyzes the range and attributes of the traffic information service between domestic public institutions and private companies, and suggests the possibility of joint application of node-link information for each company and the possibility of joint use of private traffic information. For this purpose, the present condition and attributes of domestic and foreign traffic information node-links (link length, node ID number, U-turn information, lane information, left turn information, right turn information, etc.) were analyzed. The analysis targets, the node-link of the national standard node and the two companies were analyzed. The area of the experiment was selected in Jongno-gu, Seoul, where standard-link information is complex, traffic volume is high, and various standard-links exist. The experiment was conducted by comparing and analyzing the traffic information attributes of three types of node-links and performing node-links overlapping matching (utilizing encoding_decoding method), and the possibility of matching node-links and attributes of different specifications was analyzed using Open LR technique.