• Review of KIISC
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• v.32 no.4
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• pp.7-17
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• 2022

운전자 보조 시스템을 통한 차량의 전자적인 제어를 위하여, 최근 차량에 탑재된 전자 제어 장치 (ECU; Electronic Control Unit)의 개수가 급증하고 있다. ECU는 효율적인 통신을 위해서 차량용 내부 네트워크인 CAN(Controller Area Network)을 이용한다. 하지만 CAN은 기밀성, 무결성, 접근 제어, 인증과 같은 보안 메커니즘이 고려되지 않은 상태로 설계되었기 때문에, 공격자가 네트워크에 쉽게 접근하여 메시지를 도청하거나 주입할 수 있다. 악의적인 메시지 주입은 차량 운전자 및 동승자의 안전에 심각한 피해를 안길 수 있기에, 최근에는 주입된 메시지를 식별하기 위한 침입 탐지 시스템(IDS; Intrusion Detection System)에 대한 연구가 발전해왔다. 특히 최근에는 AI(Artificial Intelligence) 기술을 이용한 IDS가 다수 제안되었다. 그러나 제안되는 기법들은 특정 공격 데이터셋에 한하여 평가되며, 각 기법에 대한 탐지 성능이 공정하게 평가되었는지를 확인하기 위한 평가 프레임워크가 부족한 상황이다. 따라서 본 논문에서는 machine learning/deep learning에 기반하여 제안된 차랑용 IDS 5가지를 선정하고, 기존에 공개된 데이터셋을 이용하여 제안된 기법들에 대한 비교 및 평가를 진행한다. 공격 데이터셋에는 CAN의 대표적인 4가지 공격 유형이 포함되어 있으며, 추가적으로 본 논문에서는 메시지 주기 유형을 활용한 공격 유형을 제안하고 해당 공격에 대한 탐지 성능을 평가한다.

• Korean Journal of Exercise Nutrition
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• v.13 no.2
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• pp.109-113
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• 2009

The objective of this study was to compare the effects of a combined treatment consisting of an isoflavone diet and aerobic exercise on the Caspase 9 levels, and Bcl-2 levels during menopause, using 30 S.D ovariectomized rats as a model, over 12 weeks. The ovariectomized rats were divided into 4 experiment groups, with 8 rats in each group, as follows: (1) General diet group (GD, n=8), (2) Isoflavone diet group (ID, n=8), (3) General diet + Exercise group (GEX, n=8), (4) Isoflavone diet + Exercise group (IEX, n=8). The findings of this study were as follows: 1. Combined treatment consisting of an isoflavone diet and regular exercise resulted in a significant reduction in the expression of caspase-9 proteins (p<0.05), and a significant increase in the expression of Bcl-2 proteins (P<0.001). In addition, apoptotic cells were more decreased (p<0.001) in GEX and IEX group. This also suggests that cardiovascular disease in postmenopausal women might be prevented or inhibited to exert positive apoptotic inhibitory effects by increasing Bcl-2 protein expression within aortic tissues during vascular movement and decrease caspase-9 protein.

• Journal of Drive and Control
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• v.20 no.4
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• pp.133-139
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• 2023

A weighing system calculates the bucket's excavation amount of an excavator. Usually, the excavation amount is computed by the excavator's motion equations with sensing data. But these motion equations have computing errors that are induced by assumptions to the linear systems and identification of the equation's parameters. To reduce computing errors, some commercial weighing system incorporates particular motion into the excavation process. This study introduces a linear regression model on an artificial neural network that has fewer predicted errors and doesn't need a particular pose during an excavation. Time serial data were gathered from a 30tons excavator's loading test. Then these data were preprocessed to be adjusted by MPL (Multi Layer Perceptron) or CNN (Convolutional Neural Network) based linear regression models. Each model was trained by changing hyperparameter such as layer or node numbers, drop-out rate, and kernel size. Finally ID-CNN-based linear regression model was selected.

• Research in Plant Disease
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• v.29 no.4
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• pp.452-458
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• 2023

In the Goesan region, located in Chungcheongbuk-do, Korea, a significant outbreak of soft rot infections was documented in August 2021, affecting fruits of Momordica charantia, commonly known as bitter melon or bitter gourd. The symptoms included a noticeable transition to yellowing in the affected fruits, eventually leading to their collapse. The bacterial strain KNUB-09-21 was isolated from the diseased fruits. Molecular analysis, using the sequences of the 16S rRNA region and three housekeeping genes (dnaX, recA, and leuS), along with the results of compound utilization in the API ID 32 GN system, provide strong evidence for the identification of the isolate KNUB-09-21 as Pectobacterium brasiliense. The pathogenicity of strain KNUB-09-21 on M. charantia was confirmed through a controlled inoculation test. Within two days, inoculated fruits displayed soft rot symptoms closely resembling those observed in naturally affected fruits. This is the first report of soft rot on M. charantia in Korea.

• Microbiology and Biotechnology Letters
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• v.26 no.6
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• pp.471-475
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• 1998

The aim of the present research program was to develop a strain of gastrointestinal bacteria containing antitumor substances. Fecal samples were collected from neonates and a number of gastrointestinal bacteria were isolated from the fecal samples by applying selective agar for intestinal bacteria. Among 127 isolates, a strain 2B4-1 containing an antitumor substance against stomach cancer, SNU-1, was selected. The strain 2B4-1 was identified as a strain similar to Enterococcus faecalis NCTC 775 with respect to morphological characteristics, growth temperature, salt and acid tolerance, growth under facultative anaerobic conditions and utilization of carbon sources such as arabinose and melibiose and so on. However, it showed some differences such as a negative reaction to hippurate hydrolysis and negative reaction to $\beta$-hemolysis. We assigned to the strain 2B4-1 to Enterococcus faecalis.

• The Transactions of the Korea Information Processing Society
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• v.7 no.7
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• pp.2149-2160
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• 2000

Recently many efforts on the development of automatic processing system for delivery sequence sorting have been performed in ETRI, which requires the use of postal4-state bar code system to encode delivery points. The 4-state bar code called postal 4-state barcode for high speed processing that has been specifically designed for information processing of logistics and automatic processing of he mail items. The Information of 4-state bar code indicates mail data such as post code, delivery sequence number, error correction code worked, customer information, and a unique ID. This appear addresses the issue on he reduction of reading error in postal 4-state raster beam based bar code reader. The raster beam scanning features are the unequally distributed number of spots per each unit, which cause reading errors. We propose a method for reducing the bar code reading error by adjusting measured values of bar code width to its average value over each interval. The test results show that the above method reduces the average reading error rate approximately by 99.88%.

• Interdisciplinary Bio Central
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• v.2 no.3
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• pp.8.1-8.5
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• 2010

Introduction: Recently identified human homologues of ALKB protein have shown the activity of DNA damaging drugs, used for cancer therapy. Bioinformatics study of hABH2 and hABH3 had led to the discovery of a novel DNA repair mechanism. Very little is known about structure and function of hABH4, one of the members of this superfamily. Therefore, in present study we are intended to predict its structure and function through various bioinformatics tools. Materials and Methods: Modeling was done with modeler 9v7 to predict the 3D structure of the hABH4 protein. This model was validated with the program Procheck using Ramachandran plot statistics and was submitted to PMDB with ID PM0076284. The 3d2GO server was used to predict the functions. Residues at protein ligand and protein RNA binding sites were predicted with 3dLigandSite and KYG programs respectively. Results and Discussion: 3-D model of hABH4, ALKBH4.B99990003.pdb was predicted and evaluated. Validation result showed that 96.4 % residues lies in favored and additional allowed region of Ramachandran plot. Ligand binding residues prediction showed four Ligand clusters, having 24 ligands in cluster 1. Importantly, conserved pattern of Glu196-X-Pro198- Xn-His254 in the functional domain was detected. DNA and RNA binding sites were also predicted in the model. Conclusion and Prospects: The predicted and validated model of human homologue hABH4 resulted from this study may unveil the mechanism of DNA damage repair in human and accelerate the research on designing of appropriate inhibitors aiding in chemotherapy and cancer related diseases.

• Food Science and Preservation
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• v.10 no.2
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• pp.224-229
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• 2003

This study was carried out to isolate of antagonistic bacterium to Allium cepa L. pathogens. A total of 250 strains were isolated from A. cepa L. roots. The isolates were screened for antagonism to A. cepa L. pathogens and the isolated strain No. YJ-4 was selected among these bacteria. It was identified as Bacillus ehimensis based on morphological and physiological characteristics according to the Bergey's mannual of systematic bacteriology, Sherlock system of Microbial ID Int and 165 rDNA sequences methods. Bacillus ehimensis YJ-4 showed broad spectrum of antibacterial and antifungal activities against plant pathogens as Alternaria porri, Botrytis cinerea, Erwinia carotovora subsp. carotovora Fusarium of oxysporium, penicillium sp., Pseudomonas sp., Rhizoctonia solani, Sclerotium cepivotum, Septoria sp., Stemphylium botryosum. Speially B. ehimensis YJ-4 showed high antifungal activity on growth against F. oxysporium, the causal agent of onion Fusarium wilt.

• Mass Spectrometry Letters
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• v.8 no.3
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• pp.59-64
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• 2017

In clinical diagnosis, it's well known that the abnormal level of uric acid (UA) in human body is implicated in diverse human diseases, for instance, chronic heart failure, gouty arthritis, diabetes, and so on. As a primary method, an isotope dilution mass spectrometry (IDMS) has been used to obtain the accurate quantity of UA in blood or serum and also develop the certificated reference material (CRM) so as to provide a SI-traceability to clinical laboratories. Due to the low solubility of UA in water, an ammonium hydroxide ($NH_4OH$) has been considered as a promising solvent to increase the solubility of UA that enables the preparation of both UA and its isotope standard solution for next IDMS-based absolute quantification. But, because of using this $NH_4OH$ solvent, it gives rise to the unwanted degradation of UA. In this study, we sought to optimize condition for the stability of UA in $NH_4OH$ solution by varying the mole ratios of UA to $NH_4OH$, followed by ID-LC-MRM analysis. In addition, we also inspected minutely the effect of the storage temperatures. Additionally, we also performed the quantitative analysis of UA in the KRISS serum certificated reference material (CRM, 111-01-02A) with diverse mixing ratios of UA to $NH_4OH$ and then compared those values to its certification value. Based on our experiments, adjusting the mole ratio of 1/2 ($UA/NH_4OH$) with the storage temperature of $-20^{\circ}C$ is an effective way to secure both the solubility and stability of UA in $NH_4OH$ solution for next IDMS-based quantification of UA in serum.

• Analytical Science and Technology
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• v.29 no.4
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• pp.170-178
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• 2016

Accuracy and precision of ID methods for different spike isotopes of ⁷⁶Se, ⁷⁷Se, and ⁷⁸Se were compared for the analysis of Selenium using quadrupole ICP/MS equipped with Octopole reaction cell. From the analysis of Se inorganic standard solution, all of three spikes showed less than 1 % error and 1 % RSD for both short-term (a day) and long-term (several months) periods. They showed similar results with each other and ⁷⁸Se showed was a bit better than ⁷⁶Se and ⁷⁷Se. However, different spikes showed different results when NIST SRM 1568a and SRM 2967 were analyzed because of the several interferences on the m/z measured and calculated. Interferences due to the generation of SeH from ORC was considered as well as As and Br in matrix. The results showed similar accuracy and precisions against SRM 1568a, which has a simple background matrix, for all three spikes and the recovery rate was about 80% with steadiness. The %RSD was a bit higher than inorganic standard (1.8 %, 8.6 %, and 6.3 % for ⁷⁸Se, ⁷⁶Se and ⁷⁷Se, respectively) but low enough to conclude that this experiment is reliable. However, mussel tissue has a complex matrix showed inaccurate results in case of ⁷⁸Se isotope spike (over 100 % RSD). ⁷⁶Se and ⁷⁷Se showd relatively good results of around 98.6 % and 104.2 % recovery rate. The errors were less than 5 % but the precision was a bit higher value of 15 % RSD. This clearly shows that Br interferences are so large that a simple mathematical calibration is not enough for a complex-matrixed sample. In conclusion, all three spikes show similar results when matrix is simple. However, ⁷⁸Se should be avoided when large amount of Br exists in matrix. Either ⁷⁶Se or ⁷⁷Se would provide accurate results.