• Title/Summary/Keyword: IC Method

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Screening of Korean Medicinal and Food Plants with Antitumoral Activity (국내 약용 및 식용식물중 항종양활성 식물탐색)

  • Chung, Ill-Min;Kim, Kwang-Ho;Ahn, Joung-Kuk;Ahn, Jong-Seog;Ahn, Soon-Cheol
    • Korean Journal of Medicinal Crop Science
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    • v.7 no.1
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    • pp.37-44
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    • 1999
  • This study was conducted to screen antitumoral activity by in vitro bioassay method using 60 Korean medicinal and food plants extracted by 80% EtOH. Antitumor activity test was applied by the PKC(protein kinase C) and antibleb formation, PLC (Phospholipase C), and colorimetric tetrazolium assay (MTT assay) methods. Chenopodjum album and black Glycine max showed high antitumoral activity by 73.5% and 81.0%, respectively, against PKC by bleb-forming assay and PKC enzyme assay on human chronic leukemia K562 cell. Black Glycine max also showed 91.2% antitumoral activity in the PLC method and the lowest $IC_{50}$ $value(4.7{\mu}g/ml)$ by MTT method against P-338 cell line. In the effect of the concentration treatment on antitumoral test, the more concentration indicated the more activity value.

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Hierarchical Grouping of Line Segments for Building Model Generation (건물 형태 발생을 위한 3차원 선소의 계층적 군집화)

  • Han, Ji-Ho;Park, Dong-Chul;Woo, Dong-Min;Jeong, Tai-Kyeong;Lee, Yun-Sik;Min, Soo-Young
    • Journal of IKEEE
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    • v.16 no.2
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    • pp.95-101
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    • 2012
  • A novel approach for the reconstruction of 3D building model from aerial image data is proposed in this paper. In this approach, a Centroid Neural Network (CNN) with a metric of line segments is proposed for connecting low-level linear structures. After the straight lines are extracted from an edge image using the CNN, rectangular boundaries are then found by using an edge-based grouping approach. In order to avoid producing unrealistic building models from grouping lined segments, a hierarchical grouping method is proposed in this paper. The proposed hierarchical grouping method is evaluated with a set of aerial image data in the experiment. The results show that the proposed method can be successfully applied for the reconstruction of 3D building model from satellite images.

The study of sound source synthesis IC to realize the virtual engine sound of a car powered by electricity without an engine (엔진 없이 전기로 구동되는 자동차의 가상 엔진 음 구현을 위한 음원합성 IC에 관한 연구)

  • Koo, Jae-Eul;Hong, Jae-Gyu;Song, Young-Woog;Lee, Gi-Chang
    • The Journal of the Acoustical Society of Korea
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    • v.40 no.6
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    • pp.571-577
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    • 2021
  • This study is a study on System On Chip (SOC) that implements virtual engine sound in electric vehicles without engines, and realizes vivid engine sound by combining Adaptive Difference PCM (ADPCM) method and frequency modulation method for satisfaction of driver's needs and safety of pedestrians. In addition, by proposing an electronic sound synthesis algorithm applying Musical Instrument Didital Interface (MIDI), an engine sound synthesis method and a constitutive model of an engine sound generation system are presented. In order to satisfy both drivers and pedestrians, this study uses Controller Area Network (CAN) communication to receive information such as Revolution Per Minute (RPM), vehicle speed, accelerator pedal depressed amount, torque, etc., transmitted according to the driver's driving habits, and then modulates the frequency according to the appropriate preset parameters We implemented an interaction algorithm that accurately reflects the intention of the system and driver by using interpolation for the system, ADPCM algorithm for reducing the amount of information, and MIDI format information for making engine sound easier.

Radiosensitivity Enhancement by Arsenic Trioxide in Conjunction with Hyperthermia in the EC-1 Esophageal Carcinoma Cell Line

  • Cui, Yan-Hui;Liang, Hai-Jun;Zhang, Qing-Qin;Li, Si-Qing;Li, Xiao-Rui;Huo, Xiao-Qing;Yang, Qing-Hui;Li, Wei-Wei;Gu, Jian-Fa;Hua, Qin-Liang;Lu, Ping;Miao, Zhan-Hui
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1693-1697
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    • 2012
  • Objective: To explore the effect on radiosensitivity of arsenic trioxide ($As_20_3$) in conjunction with hyperthermia on the esophageal carcinoma EC-1 cell line. Method: Inhibition of EC-1 cell proliferation at different concentrations of $As_20_3$ was assessed using the methyl thiazolyl blue colorimetric method (MTT method), with calculation of $IC_{50}$ value and choice of 20% of the $IC_{50}$ as the experimental drug concentration. Blank control, $As_20_3$, hyperthermia, radiotherapy group, $As_20_3$ + hyperthermia, $As_20_3$ + radiotherapy, hyperthermia + radiotherapy and $As_20_3$ + hyperthermia + radiotherapy groups were established, and the cell survival fraction (SF) was calculated from flat panel colony forming analysis, and fitted by the 'multitarget click mathematical model'. Flow cytometry (FCM) was used to detect changes in cell apoptosis and the cell cycle. Results: $As_20_3$ exerted inhibitory effects on proliferation of esophageal carcinoma EC-1 cells, with an $IC_{50}$ of 18.7 ${\mu}mol/L$. After joint therapy of $As_20_3$ + hyperthermia + radiotherapy, the results of FCM showed that cells could be arrested in the $G_2$/M phase, and as the ratio of cells in $G_0/G_1$ and S phases decreased, cell death became more pronounced. Conclusion: $As_20_3$ and hyperthermia exert radiosensitivity effects on esophageal carcinoma EC-1 cells, with synergy in combination. Mechanistically, $As_20_3$ and hyperthermia mainly influence the cell cycle distribution of EC-1 esophageal carcinoma cells, decreasing the repair of sublethal damage and inducing apoptosis, thereby enhancing the killing effects of radioactive rays.

Validation of analytical method and antioxidant properties of Eriobotrya japonica Lindl. Leaf extract according to extraction solvent (추출용매 조건에 따른 비파 잎 추출물의 항산화 활성 및 유효성분의 분석법 밸리데이션)

  • Kim, Hyun-Hee;Heo, Mi-Ra;Lee, Songmi;Yim, Soon-Ho
    • Korean Journal of Food Science and Technology
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    • v.51 no.4
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    • pp.301-308
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    • 2019
  • The antioxidant properties of Eriobotrya japonica leaf extract were investigated using DPPH and ABTS radical scavenging assay. The 80% ethanol extract of leaves ($IC_{50}$ values for DPPH and ABTS were 13.9 and $10.9{\mu}g/mL$, respectively) and young leaves ($IC_{50}$ values for DPPH and ABTS were 20.7 and $17.3{\mu}g/mL$, respectively) showed high radical scavenging activity. Additionally, the quantitative method for estimation of ellagic acid and chlorogenic acid from E. japonica leaves was optimized by HPLC/DAD. This method showed high linearity of the calibration curve with a coefficient of correlation ($R^2$) equal to 0.999. The LOD values for ellagic acid and chlorogenic acid were 2.35 and $0.73{\mu}g/mL$, respectively, whereas LOQ values were 7.13 and $2.22{\mu}g/mL$, respectively. Recovery of the two compounds was 99.7-108.0% with RSD values less than 5.31%. These results suggest that 80% ethanol extract of E. japonica leaves could serve as a potential source of natural antioxidant for us in various industrial applications.

An Advanced Coding for Video Streaming System: Hardware and Software Video Coding

  • Le, Tuan Thanh;Ryu, Eun-Seok
    • Journal of Internet Computing and Services
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    • v.21 no.4
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    • pp.51-57
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    • 2020
  • Currently, High-efficient video coding (HEVC) has become the most promising video coding technology. However, the implementation of HEVC in video streaming systems is restricted by factors such as cost, design complexity, and compatibility with existing systems. While HEVC is considering deploying to various systems with different reached methods, H264/AVC can be one of the best choices for current video streaming systems. This paper presents an adaptive method for manipulating video streams using video coding on an integrated circuit (IC) designed with a private network processor. The proposed system allows to transfer multimedia data from cameras or other video sources to client. For this work, a series of video or audio packages from the video source are forwarded to the designed IC via HDMI cable, called Tx transmitter. The Tx processes input data into a real-time stream using its own protocol according to the Real-Time Transmission Protocol for both video and audio, then Tx transmits output packages to the video client though internet. The client includes hardware or software video/audio decoders to decode the received packages. Tx uses H264/AVC or HEVC video coding to encode video data, and its audio coding is PCM format. By handling the message exchanges between Tx and the client, the transmitted session can be set up quickly. Output results show that transmission's throughput can be achieved about 50 Mbps with approximately 80 msec latency.

Logic Implementation of HDB3 Codec (HDB3 Codec의 로직구현)

  • Eom, Joon;Kim, Young-Kil
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.22 no.2
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    • pp.369-374
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    • 2018
  • The Line Code is a code used for data transmission and is a coding method used to prevent loss of data between transmitter and receiver. There are various kinds of line code such as B3ZS, HDB3, B8ZS, and HDB3 code is used in the tactical communication networks of Korea. In this paper, we implement the HDB3 Codec that is used in tactical communication networks in order to eliminate the risk factors for component discontinuance and to shorten development period and ensure reliability. Also it is confirmed that it can be implement by minimizing the amount of logic usage so that it can be used unrestrictedly in systems using FPGA and the implemented HDB3 Codec is simulated to confirm that it is equivalent to the performance of HDB3 Codec IC.

Design of an electronic dimming ballast circuit for a fluorescent lamp and its remote control system (형광램프용 Dimming 형 전자식 안정기 및 원격제어시스템의 회로설계)

  • 송상빈;곽재영;여인선
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.13 no.2
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    • pp.17-23
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    • 1999
  • This paper is to present a selected method of circuit parameters in the inverter part of the electronic dimming ballast fer fluorescent lamps, that is adffIuate to use with the prevailing dimming controller IC. Through the experirrent result using the prototype of the electronic dimming ballast rroduced by this rrethod, its validity is verified from the electrical and light outplt characteristics on fluorescent lamps. Also, it is feasible to rerrnte automatic and passive control for dimming electronic ballast as using a micrqrocessor, and we easily recognize the lamp condition owing to rmke a program indicate abnormal behavior for fluorescent lamp at PC screen.screen.

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Selective Cytotoxic Effects of Doenjang (Korean Soybean Paste) Fermented with Bacillus Strains on Human Liver Cell Lines

  • Choi, Myeong-Rak;Lim, Hyun-Soo;Chung, Yoon-Ju;Yoo, Eun-Jeong;Kim, Jong-Kyu
    • Journal of Microbiology and Biotechnology
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    • v.9 no.4
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    • pp.504-508
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    • 1999
  • This report compares the selective cytotoxic effects of Doenjang fermented by various Bacillus strains (Bacillus sp. SS9, SSA3, and PM3) on human liver cell lines with that of conventional Doenjang (DTY, DTG, and DTK) and commercial Doenjang (DCM, DCD, and DCS). To investigate selective cytotoxic effects of Doenjang extracts, the cell density of HepG2 (Hepatocellular carcinoma) and CCL-13 (cells derived from human normal liver) was estimated after addition of the extracts by using a viable cell counting method. The maximum selectivity ratio ($IC_{50}$value against CCL-13/$IC_{50}$ value aganist HepG2) was observed by PM3 (extracts of Doenjang fermented with Bacillus sp. PM3). As for morphological changes shown by the addition of PM3 into HepG2 and CCL-13 cultures, HepG2 was significantly disrupted, however, CCL-13 was not affected. Also, the growth rate of HepG2 was decreased significantly by the addition of PM3. Consequently, PM3 showed a more detrimental effect on HepG2 than that on CCL-13.

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Thermal Properties and fracture Toughness of Difunctional Epoxy Resins Cured by Catalytic Initiators (촉매형 개시제로 경화된 이관능성 에폭시 수지의 열적 특성 및 파괴인성)

  • 박수진;허건영;이재락
    • Polymer(Korea)
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    • v.26 no.3
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    • pp.344-352
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    • 2002
  • In this work, two thermal cationic latent catalysts, i.e., triphenyl benzyl phosphonium hexafluoroantimonate (TBPH) and benzyl 2-methylpyrazinium hexafluoroantimonate (BMPH) were newly synthesized. And the thermal and mechanical properties of difunctional epoxy (diglycidylether of bisphenol h, DGEBA) resins initiated by 1 phr of either TBPH or BMPH catalyst were investigated. As experimental results, the epoxy/TBPH system showed higher curing temperature and critical stress intensity factor ($K_{IC}$) than those of epoxy/BMPH. This could be interpreted in terms of slow thermal diffusion rate and bulk structure of four phenyl groups in TBPH. However, the decomposed activation energy determined from Coats-Redfern method was lower in the case of epoxy/TBPH. This result was probably due to the fact that broken short chain structure was developed by steric hindrance of TBPH.