• 대한한방내과학회지
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• 제42권4호
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• pp.532-546
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• 2021

Objective: This study investigated the perception, diagnosis, and treatment of irritable bowel syndrome (IBS) in the general population, in patients, and in Korean medicine doctors (KMDs) in order to provide basic information for the development of Korean medicine clinical practice guidelines for IBS. Methods: A questionnaire was developed in two versions, one for the general population/patients and one for KMDs. The questions were about the general perception, diagnosis, and treatment of IBS. Both online and offline surveys were conducted using these questionnaires. Results: In total, 213 general population/patients and 435 KMDs responded to the survey. The results of the analysis were as follows. Most of the KMDs diagnosed IBS based on clinical aspects. Acupuncture was the most common treatment, followed by prescription herbal medicine, moxibustion, and manufactured herbal medicine. 34.3% of KMDs used clinical practice guidelines for IBS patient treatment. 57.8% of patients were diagnosed with IBS by doctors at primary medical institutions, and 53.1% were diagnosed with colonoscopy. More than half of the IBS patients who have been treated with Korean medicine said they experienced improvement of symptoms and prevention of recurrence, but more than 70% of the respondents said future safety and effectiveness studies of Korean medicine were needed. Conclusions: In spite of the positive perception of IBS treatment with Korean medicine, actual utilization was relatively low. The development and promotion of, as well as education about, appropriate and reasonable Korean medicine practice guidelines for IBS is necessary.

• BMB Reports
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• 제52권4호
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• pp.283-288
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• 2019

$Foxp3^+$ regulatory $CD4^+$ T (Treg) cells play an essential role in preventing overt immune responses against self and innocuous foreign antigens. Selective expansion of endogenous Treg cells in response to the administration of interleukin (IL)-2/antibody complex, such as the IL-2/JES6-1 complex (IL-2C) in mice, is considered an attractive therapeutic approach to various immune disorders. Here, we investigated the therapeutic potential of IL-2C in allergic airway inflammation models. IL-2C treatment ameliorated Th17-mediated airway inflammation; however, unexpectedly, IL-2C treatment exacerbated Th2-mediated allergic airway inflammation by inducing the selective expansion of Th2 cells and type-2 innate lymphoid cells. We also found that IL-2 signaling is required for the expansion of Th2 cells in lymphoproliferative disease caused by Treg cell depletion. Our data suggest that IL-2C is selectively applicable to the treatment of allergic airway diseases depending on the characteristics of airway inflammation.

• 여성건강간호학회지
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• 제14권4호
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• pp.306-313
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• 2008

Purpose: The purpose of study was to explore the frequency of irritable bowel syndrome(IBS) among female university students and identify self-esteem, depression, and physical health. Method: The secondary analysis was performed. A total 401 university female students were recruited from 1 university in Korea. IBS was diagnosed based on the Rome III criteria. The questionnaires included Rosenberg's self-esteem scale, Center for Epidemiological Studies-Depression(CESD) scale, and physical health questionnaire developed by Lee. The collected data was analyzed with SPSS Win 15.0 statistics program using frequencies, percentages, ANOVA, and the Pearson's correlations of the variables. Result: The frequency of IBS was 26.7% in students. All women had mixed constipation and diarrhea subtype of IBS. Compared to the women without IBS, those with IBS reported significantly lower scores on self-esteem and higher scores of CESD and on the physical health questionnaire. Conclusion: Nursing interventions targeting female students with IBS should be developed in order to reduce the depression and physical health problem and improve self-esteem.

• 대한간호학회지
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• 제43권5호
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• pp.579-586
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• 2013

Purpose: This article provides an update and overview of a nursing research program focused on understanding the pathophysiology and management of irritable bowel syndrome (IBS). Methods: This review includes English language papers from the United States, Europe, and Asia (e.g., South Korea) from 1999 to 2013. We addressed IBS as a health problem, emerging etiologies, diagnostic and treatment approaches and the importance of a biopsychosocial model. Results: IBS is a chronic, functional gastrointestinal disorder characterized by recurrent episodes of abdominal pain and alterations in bowel habit (diarrhea, constipation, mixed). It is a condition for which adults, particularly women ages 20-45, seek health care services in both the United States and South Korea. Clinically, nurses play key roles in symptom prevention and management including designing and implementing approaches to enhance the patients' self-management strategies. Multiple mechanisms are believed to participate in the development and maintenance of IBS symptoms including autonomic nervous system dysregulation, intestinal inflammation, intestinal dysbiosis, dietary intolerances, alterations in emotion regulation, heightened visceral pain sensitivity, hypothalamic-pituitary-adrenal dysregulation, and dysmotility. Because IBS tends to occur in families, genetic factors may also contribute to the pathophysiology. Patients with IBS often report a number of co-morbid disorders and/or symptoms including poor sleep. Conclusion: The key to planning effective management strategies is to understand the heterogeneity of this disorder. Interventions for IBS include non-pharmacological strategies such as cognitive behavior therapy, relaxation strategies, and exclusion diets.

• Journal of Korean Biological Nursing Science
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• 제11권2호
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• pp.167-175
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• 2009

Purpose: The purpose of this study was to examine the prevalence and factors on Irritable Bowel Syndrome (IBS) symptoms in university students. Methods: This study was descriptive survey research. The subjects were 187 university students from one university. The exclusion criteria were 1) had GI surgery 2) had severe physiologic or psychologic problems 3) had liver, bile duct, pancreatic, and intestinal disease that required treatment. The ROME III was used to diagnose IBS. Sociodemographic characteristics, general health state by SF-36, psychological health by SCL-90-R, stress by perceived stress scale, sleep disturbance by Korean sleep scale, and diet habits were measured. Data were analyzed by using SPSS 17.0. Results: Seventeen students (9.1%) had IBS by ROME III criteria, but 46% had some GI problems at that time. Abdominal pain or discomfort continued for last six months or more in 14.3%. Fiber intake, obsessive-compulsiveness, hostility, psychoticism, global severity index, positive symptom distress, role physical, bodily pain, social functioning, and mental health were significantly different between IBS group and Non IBS group. Conclusion: Over nine percent of the students were diagnosed by Rome III criteria, and almost half of them had some GI problems. Diet, personality, general health state, and psychological health were factors of IBS.

• 기본간호학회지
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• 제16권2호
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• pp.171-180
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• 2009

Purpose: This study was done to examine the frequency of irritable bowel syndrome (IBS), entrance examination stress, mental health, and quality of life among adolescent women. Methods: A survey conducted to collect data from 925 adolescent women in Gyeonggi Province. The measurements included the Rome III criteria (to diagnose IBS), the entrance examination stress scale (to evaluate stress), symptom check list90R (SCL-90R to evaluate mental health), and World Health Organization Quality of Life Abbreviated Version (WHOQOL-BREF to evaluate quality of life). Frequency, $X^2$-tests, t-test, and analysis of variance (ANOVA) with the SPSS 16.0 program were used to analyze the data. Results: The frequency of IBS in the women was 22.8%. One hundred thirty eight women (65.4%) had the mixed constipation and diarrhea subtype of IBS. Compared to the women without IBS, those with IBS reported significantly higher scores on entrance examination stress scale, SCL-90R, all subscales of SCL-90R, and lower scores on WOLQOL-BREF. Conclusion: Nursing interventions targeting adolescent women with IBS should be developed in order to alleviate the associated stress and mental health and to promote quality of life.

• 여성건강간호학회지
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• 제22권2호
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• pp.96-103
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• 2016

Purpose: This study was to investigate impacts of daily habits, health status and health promoting behavior on prevalence of irritable bowel syndrome (IBS) among female high school students. Methods: The survey was conducted from 526 female students in high school. Rome III criteria was used to diagnose IBS. Data of daily habits, health status, and health promoting behavior were collected through self-administered structured questionnaires. Results: The prevalence of IBS was 25.7%. Compared to the non-IBS, the IBS group scored significantly lower in exercise time, sleeping time, four dimensions of health status (physical, emotional, social, spiritual health) and management of relationship and stress in health promoting behavior. Risk factors influencing IBS were exercise time, physical health and emotional health status. Conclusion: The results of this study suggest that nursing interventions and education programs are important to be developed, while considering exercise, health status and health promoting behaviors for female adolescents in order to manage their IBS.

• 한국한의학연구원논문집
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• 제2권1호
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• pp.327-336
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• 1996

IBS(Irritable bowel syndrome) means disorder of intestinal motility. To increase the cure rate of IBS, we have observed and analysed 26 persons who have administered Ansinbobitang(安神補脾湯), Ansinbobitang(安神補脾湯) consists of herb medicines which have tranquilizational(安神), reinforcing the spleen(補脾), and tonifying the kidney's Yang(補腎陽) effects. From this study we obtained as follows. 1. 16 cases of IBS patients were male and 10 cases were female. Male of female ratio was 1 : 1.6, and the peak age in incidence of IBS was in End and 3rd decade. 2. Duration of IBS attack, the most frequence is $0{\sim}1$ year and $3{\sim}5$ years. 3. Seasonal distribution of IBS attack reveals the peak occurrence in autumn. 4. Duration of treatments, the most frequence is $2{\sim}3$ weeks. 5. Ansinbobitang(安神補脾湯) shows 88.5% of effective rate.

• 한국정보통신학회논문지
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• 제18권7호
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• pp.1540-1546
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• 2014

인도어 기지국(Indoor BS) 결함으로 인해 발생하는 커버리지홀 문제를 해결하기 위하여, 새로운 프레임 구조와 최적화 기법 기반의 실제적인 알고리즘을 제안한다. 우리의 핵심 공헌은 다음과 같다: 1) 갑작스런 IBS 결함 문제 해결을 위한 힐링(healing) 채널을 가지는 새로운 프레임 구조를 제안하고 2) 최적화 문제의 복잡도 감소를 위한 고정적 IBS 선택에 기반한 효과적인 휴리스틱 자원할당 알고리즘을 제안한다. 시뮬레이션을 통하여 평균 셀 용량과 사용자 공평성 관점에서 기존 알고리즘에 비해 제안 방안이 우수함을 증명한다.

• Steel and Composite Structures
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• 제25권2호
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• pp.245-255
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• 2017

The performance of an Industrialised Building System (IBS) consists of prefabricated reinforced concrete components, is greatly affected by the behaviour of the connection between beam and columns. The structural characteristics parameters of a beam-to-column connection like rotational stiffness, strength and ductility can be explained by load-rotation relationship of a full scale H-subframe under gravitational load. Furthermore, the connection's degree of rigidity directly influences the behaviour of the whole frame. In this research, rotational behaviour of a patented innovative beam-to-column connection with unique benefits like easy installation, no wet work, no welding work at assembly site, using a hybrid behaviour of steel and concrete, easy replacement ability, and compatibility with architecture was investigated. The proposed IBS beam-to-column connection includes precast concrete components with embedded steel end connectors. Two full-scale H-subframes constructed with a new IBS and conventional cast in-situ reinforced concrete system beam-to-column connections were tested under incremental static loading. In this paper, load-rotation relationship and ratio of the rigidity of IBS beam-to-column connection are studied and compared with conventional monolithic reinforced concrete connection. It is concluded that this new IBS beam-to-column connection benefits from more rotational ductility than the conventional reinforced concrete connection. Furthermore, the semi-rigid IBS connection rigidity ratio is about 44% of a full rigid connection.