• 한국동물위생학회지
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• 제21권3호
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• pp.277-284
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• 1998

Serum samples were collected from 100 breeders and their progeny 600 broilers. The breeders and broilers were vaccinated against infectious bronchitis(IB), infectious bursal disease(IBD) and Newcastle disease(ND) viruses according to general vaccination program. The antibodies in serum samples against IB, IBD and ND viruses were detected by ELISA using commercial ELISA kit. Geometric mean titer(GMT) of ELISA was monitored from 1-day-old to 35-day-old broilers and compared to that of breeder chickens. The GMT of ELISA to IB, IBD and ND was declined half level of the day old broiler's antibody titers at about 4, 9 and 4 days of age. The GMT of ELISA to IB, IBD and ND was declined than that of protective antibody titer at about 12, 11, and 15 days of age. Thereafter, the GMT of ELISA to IB, ND were declined and disappeared according to age of broilers. The GMT of ELISA to IBD was declined according to age of broilers, but at 25 days of age increased and 31 days of age increased than that of protective antibody titer. Taken together, these studies led to conclusion that time-course of antibody titers of broilers from vaccinated breeders and that of progeny broliers which vaccinated according to vaccine program. Those are very important data to design vaccine program to breeders and broilers.

• Journal of the Korean Wood Science and Technology
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• 제41권6호
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• pp.544-550
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• 2013

국내에서 생산된 파티클보드에 대한 나사못 유지력을 기존의 식으로부터 수정 보완된 예측 식으로 나타내기 위해 나사못 유지력실험을 실시했다. 본 연구에 사용된 나사못은 No. 6, No. 8 및 No. 10이었다. 나사못 유지력의 예측 식은 나사못의 직경과 관입길이, 파티클보드의 비중 및 IB의 함수로 나타냈다. 예측 식은 길이가 서로 다른 No. 8 나사못의 실험결과와 상당히 일치하였다. 파티클보드에 대한 실험결과들과 표면에서 나사못 유지력의 예측 값은 비중보다 IB가 더 좋은 예측인자였고, 측면에서는 IB보다 비중이 더 일치하였다.

• Toxicological Research
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• 제26권1호
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• pp.29-35
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• 2010

The present study was conducted to investigate the antimutagenic potential of the methanolic extract from the leaves of sweet potato (Ipomea batatas, IB) with the SOS chromotest (umu test) and Salmonella typhimurium TA 98 and TA 100. The anticarcinogenic effects were also studied by calculation of the $IC_{50}$ on human cancer cell lines and investigating the function of gap junction in rat liver epithelial cells. The IB extract inhibited dose-dependently the ${\beta}$-galactosidase activity induced spontaneously at concentration of more than 200 mg/ml in S. typhimurium TA 1535/pSK 1002, and decreased significantly (p < 0.01) the ${\beta}$-galactosidase activities induced by mutagen 6-chloro-9-[3-(2-chloroethylamino)proylamino]-2-methoxyacridine dihydrochloride (ICR) at dose of more than 0.4 mg/0.1 ml. The IB extract showed no effect on the spontaneous reversions of S. typhimurium TA 98 and 100 but benzo(${\alpha}$)pyrene (BaP)-stimulated reversions were decreased dose-dependently (p < 0.01) at the concentration of more than 100 mg/ml. The $IC_{50}$ value of stomach cancer cells was lower than that of normal rat liver epithelial cells, but the values of colon and uterine cancer cell lines were similar to those of normal rat liver epithelial cells. The transfer of dye through gap junctions was not affected by treatment of the IB extracts at any concentration during treatment periods. The simultaneously treatment of IB extract and 12-O-tetradecanoylphorbol-13-acetate (TPA) effectively prevented the inhibition of dye transfer induced by TPA 1 hour after treatment at all exposed concentrations. The number of gap junctions was significantly (p < 0.01) increased by the treatment with IB extract at concentrations of more than 40 ${\mu}g$/ml. The inhibition of the expression of gap junction proteins by TPA (0.01 ${\mu}g$/ml) was recovered dose dependently by the simultaneous treatment of IB extracts. Our data suggest that Ipomea batatas has antimutagenic and anticarcionogenic activity in vitro.

• 생명과학회지
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• 제20권6호
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• pp.964-967
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• 2010

본 연구는 동물유래 E. coli에서 plasmid-mediated quinolone resistance (PMQR) 유전자의 분포도를 조사하였다. 55주의 E. coli를 대상으로 PCR을 수행한 결과, PMQR 양성균은 11주이었으며 그 중 2주는 두 개의 PMQR 유전자를 동시에 가지고 있었다. PMQR 유전자의 염기서열 분석 결과, qnrS, aac(6')-Ib-cr, qepA로 확인되었고 qnrS (1.8%)와 aac(6')-Ib-cr (7.3%) 보다는 qepA (14.5%)가 높은 분포도를 나타내었으며, qnrA와 qnrB는 검출되지 않았다. 11주의 PMQR 양성균의 MIC를 측정한 결과, 대부분의 PMQR 양성균이 검사한 항생제에 내성을 보였지만 일부에서 감수성 균주도 확인되었다. 또한, aac(6')-Ib-cr 유전자는 단독으로 존재할 때 보다 qnrS 또는 qepA와 함께 존재할 때 내성이 더욱 증가함을 알 수 있었다. 내성유전자 전달능 실험에서 11주 모두 PMQR 유전자를 전달하였으며, PMQR 유전자를 전달받은 수용체에서 공여체와 동일한 내성 phenotype 및 PMQR 유전자를 확인 할 수 있었다.

• 대한수의학회지
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• 제39권6호
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• pp.1141-1150
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• 1999

Renal failure is one of the main causes of economic impacts in the poultry industry and complex syndrome with different severity of clinical signs caused by multiple nephropathogenic factors such as infectious bronchitis viral infection and excess salt and calcium in diet. To evaluate the correlation between severity of renal failure and the causative nephropathogenic factors, one-day-old specific pathogen free chickens were treated with either single causative factor or multiple causative factors described as above. Each group was designed as control for non-treated control, IB for infectious bronchitis virus (IB virus) infection, IBHNa for IB virus infection with high diet salt, IBHCa for IB virus infection with high diet calcium, IBHNC for IB virus infection with high diet salt and calcium, HNa for high diet salt, HCa for high diet calcium and HNC for high diet salt and calcium. Chickens were inoculated with IB virus at 1-day-old and remained on their respective diets until 21 day of age. Plasma $Na^+$, $Cl^-$, BUN, creatinine, calcium and uric acid values were examined. The results obtained were as follows ; IB virus and high dietary calcium combined treatment showed elevated plasma uric acid. BUN and creatinine values were not characteristic on chicken renal failure. But plasma uric acid values were increased according to renal lesion. Hypercalcemia and hyperuricemia did not induce urate deposition and mineralization in the kidney.

• Journal of Information Science Theory and Practice
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• 제8권3호
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• pp.30-46
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• 2020

This research aimed (1) to study and analyze the ability of current information retrieval (IR) systems based on views of information behavior (IB), and (2) to propose a conceptual framework for an IB model based on the collaboration between the system and user, with the intent of developing an IR system that can apply intelligent techniques to enhance system efficiency. The methods in this study consisted of (1) document analysis which included studying the characteristics and efficiencies of the current IR systems and studying the IB models in the digital environment, and (2) implementation of the Delphi technique through an indepth interview method with experts. The research results were presented in three main parts. First, the IB model was categorized into eight stages, different from traditional IB, in the digital environment, which can correspond to all behaviors and be applied to with an IR system. Second, insufficient functions and log file storage hinder the system from effectively understanding and accommodating user behavior in the digital environment. Last, the proposed conceptual framework illustrated that there are stages that can add intelligent techniques to the IR system based on the collaboration perspective between the user and system to boost the users' cognitive ability and make the IR system more user-friendly. Importantly, the conceptual framework for the IB model based on the collaboration perspective between the user and system for IR assisted the ability of information systems to learn, recognize, and comprehend human IB according to individual characteristics, leading to enhancement of interaction between the system and users.

• Weed & Turfgrass Science
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• 제2권1호
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• pp.88-94
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• 2013

Rhizoctonia solani AG-1 IB에 의한 갈색잎마름병(brown patch)이 경북 청도에 있는 골프장에서 2010년 5월 하순과 10월 초순에 Kentucky bluegrass에서 발생하였다. 봄철에 발병증상은 잎끝과 잎이 마르는 증상이 갈색의 patch 형태로 나타났다. 하지만, 가을철에는 검은 갈색과 회갈색의 patch 모양으로 나타났다. 갈색잎마름병의 곰팡이는 병든 잎에서 분리를 하였으며, 동정을 위하여 PDA에서 배양하였다. 어린 균사는 분지각이 좁은 형태와 격막이 있었고, 분지각이 $90^{\circ}C$인 성숙한 균사와 monilioid 세포가 발달된 것도 볼 수 있었다. B-7 균주의 리보소옴 RNA의 염기서열을 분석하여 유전자은행에 Rhizoctonia solani AG-1 IB 균주와 비교한 결과, 99% 상동성을 나타낸다는 것을 확인하였다. 병원성도 creeping bentgrass와 Kentucky bluegrass에서 Koch's 원칙에 따라 확인하였다. Kentucky bluegrass에 갈색잎마름병은 Rhizoctonia solani AG-1 IB에 의한 것임을 처음보고 한다.

• 한국비블리아학회지
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• 제33권4호
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• pp.5-25
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• 2022

본 연구의 목적은 수요자인 학교가 교육과정 운영을 위하여 요구하는 사서교사의 직무와 역량 사례를 분석하고, 사서교사의 전문성 향상 방안을 제안하는 것이다. 이를 위하여 IB 국제학교가 사서교사를 선발하기 위하여 게시한 20건의 구인광고에 포함된 사서교사의 직무와 역량을 IFLA 학교도서관 가이드라인을 기준으로 분석하였다. 그 결과 IB 국제학교의 사서교사 직무 및 역량은 IB 교육과정 지침에 근거를 두고 있으며, 이 지침은 IBO 교육과정이 지향하는 교육이념과 학습자상에 기반을 두고 있는 것으로 나타났다. 아울러 학교가 사서교사에게 가장 많이 기대하는 직무는 도서관 장서관리 및 협동을 통한 교수이며, 이를 위한 주요 역량은 의사소통과 협동능력, 교수-학습·교육과정·교육설계 및 제공 그리고 디지털과 매체활용능력이다. 이러한 분석 결과는 사서교사의 전문성은 교육과정에서 제시하는 교육적 인간상과 학습자 역량에 기반을 두고 있어야 함을 보여준다. 이를 바탕으로 본 연구에서는 사서교사의 전문성 신장 방안을 다음과 같은 측면에서 제시하였다. 첫째, 국가 수준의 교육과정 편성 운영 지침에 학교도서관의 역할 포함하기 둘째, 학교도서관진흥법시행령 개정을 통한 인적자원의 직무 구분하기 셋째, 사서교사 자격 취득을 위한 기본이수 과목 개편 및 교육실습과 사서교사 임용시험에 협동수업 시연 도입하기 등이다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2009년도 추계학술대회 논문집
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• pp.185-185
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• 2009

The aligned liquid crystals (LCs) display on SiNx thin films using ion-beam (IB) irradiation was studied with controllability ofpretilt angle depending on incident energies of the IB. Plasma-enhanced chemical vapor deposition (PECVD) was used to orient the LCs on SiNx alignment films. The LCs alignment property for the SiNx thin films were observed to verify the practical application potential (figure1). A good LCs alignment of vertical alignment LCs cells on SiNx thin film surfaces irradiated with incident IB energy of 1800eV was achieved. Also, a good LC alignment by the IB irradiation on the SiNx thin film surface was observed at an annealing temperature of $180^{\circ}C$. However, the alignment defects of the nematic liquid crystal was observed at an annealing temperature above $230^{\circ}C$. The atomic force microscopy (AFM) images of LCs on SiNx thin film surfaces irradiated with IB energy was used for the surface analysis.

• Clinical and Experimental Pediatrics
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• 제52권12호
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• pp.1383-1387
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• 2009

저자들은 생후 18개월 여아에서 당원병 Ib 형을 경험하였기에 보고하는 바이다. 진단 시에는 호중구 감소증이 없었고, 이후 점차 중성구가 감소하여 3세에 절대적 호중구수가 $500/{\mu}L$ 미만을 보였다. 반복적인 세균 감염은 없었다. 유전자(SLC37A4) 검사에서 복합 이형접합체 과오돌연변이(Ala148Val/Gly273Asp)를 확인할 수 있었다.