• 문화기술의 융합
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• 제5권2호
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• pp.321-327
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• 2019

본 연구는 우리나라 게임물 등급 제도의 변천을 알아보고, IARC 게임물 등급 심의 시대에 맞아 문제점과 개선방안을 모색하는 데 목적이 있다. IARC는 국제등급분류연합으로, 전세계 6개 기구 37개국이 가입되어 있다. 또한, IARC는 참여 스토어 프론트에게 게임 등급 심의의 자율권을 부여하고 있다. 우리나라의 게임물 심의 방법은 등급분류제도에 의한 직접 심의와 IARC 자체등급분류제도에 의한 위임 심의로 진행되고 있다. 게임물 등급 제도의 문제점으로 민간이 주체가 된다는 점과 설문지에 의존한다는 점, 자체등급분류제도에 의한 부작용을 들 수 있다. 게임물 등급 제도 개선 방안으로 IARC 가이드라인을 구축하는 것, 게임 개발자에 대한 페널티 및 등급 심의에 대한 교육, 참여 프론트 스토어 관리를 제안할 수 있다. 결론적으로, 오픈마켓에게 등급 심의 권한을 위임하는 것은 위험할 수 있어, 정부와 업계, 게임 개발자, 이용자, 미성년 게이머의 부모들을 포함한 등급 심의 토론의 장을 구성하여, IARC 기준을 활용하여 우리나라의 현실에 맞는 게임물 등급 제도를 만들어나가야 할 것이다.

• Toxicological Research
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• 제17권
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• pp.227-236
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• 2001

The IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans has reviewed, summarized and evaluated 869 environmental agents and exposures as oj June 2000. This large collection includes all relevant published epidemiological data on cancer in exposed humans and results of bioassays for carcinogenicity in experimental animals. Since 1986. cancer data have been systematically supplemented by summaries of other toxicological data that are relevant to assessments of carcinogenic hazard. These include summaries qf genetic and related effects of chemicals. which have been prepared as Genetic Activity Profiles (GAP) by the U.S. EPA in collaboration with IARC. As the Mono-graphs have proved increasingly valuable and influential worldwide. they have evolved into an encyclopedia on environmental carcinogenic risks to humans. However. the Monographs have historically been prepared only as printed books with limited distribution. and the Monographs Programme has needed to adjust to expectations oj wider availability. Since 1998 the evaluations and summaries have been globally accessible by Internet from IARC (http://www.iarc.fr) and the GAP profiles by Internet from EPA (http://www.epa.gov/gapdb/). with the two web sites linked. Improved EPN/ARC GAP database and software. GAP2000. now link GAP profiles directly to the appropriate IARC web pages for summaries of evaluations of a given compound and its overall IARC classification. During the year 2000. by means of optical character recognition (OCR) technology the entire series of IARC Monographs is being converted to an electronic version. The first edition is now available commercially in CD-ROM format and will soon become available on-line at .

• 한국산업보건학회지
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• 제33권1호
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• pp.1-2
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• 2023

2-Bromopropane, a causative chemical that caused the outbreak of reproductive toxicity 28 years ago, was classified as Group 2A in the recently held IARC monograph 133 meeting. Korean research data were used as supporting data in the carcinogenicity evaluation of 2-bromopropane and other carcinogens. I would like to share my memories with the researchers at the Occupational Safety and Health Research Institute who worked hard to identify the cause.

• Asian Pacific Journal of Cancer Prevention
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• 제15권5호
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• pp.1891-1894
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• 2014

In February 6-7th, the Thai National Cancer Institute, the International Agency for Research on Cancer and its Mumbai Hub for Cancer Registration, together with the International Association of Cancer Registries and the APOCP/APJCP, jointly organized an Asian cancer registry forum to discuss regional cooperation for cancer registration. Held in the Grande Mercure Fortune Hotel, Bangkok, the meeting brought together leading scientists in cancer registration from South-East and North-East Asia as well as Australia, India and Iran and IARC itself, with coverage of various priorities and challenges of cancer registries regarding cancer control policy, operational parameters, assessment of survival and contributions to screening, for example. The current situation was highlighted and future directions and possible expansion of activities were discussed, with especial attention to the necessity for networks to help improve cancer registration across Asia and Africa.

• 축산식품과학과 산업
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• 제4권2호
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• pp.2-6
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• 2015

• Safety and Health at Work
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• 제15권1호
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• pp.1-8
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• 2024

Background: The International Agency for Research on Cancer (IARC) Monograph conducted a systematic review of the relationship between asbestos and ovarian cancer. However, there may have been information bias due to the undue weight given to few articles. To address this limitation, the present study performed a meta-analysis integrating studies published both before and after the 2012 IARC Monograph on Asbestos, with the aim of investigating the association between asbestos exposure and ovarian cancer. Methods: A comprehensive search of major journal databases was conducted to identify studies examining the relationship between asbestos exposure and ovarian cancer, including those featured in the 2012 IARC Monograph on Asbestos. A meta-analysis on asbestos exposure and cancer risk was performed. Results: The meta-analysis of studies published after the 2012 IARC Monograph on Asbestos found a summary Standardized Mortality Ratio (SMR) of 2.04 (95% CI: 1.03-4.05; p = 0.0123; 5 studies), with a significant degree of heterogeneity among the studies (I² = 72.99%). The combined analysis of 15 studies before and after the 2012 IARC Monograph showed an overall summary SMR of 1.72 (95% CI: 1.43-2.06; p = 0.0349; 15 studies), with a moderate degree of heterogeneity (I² = 42.99%). Conclusion: This meta-analysis provides evidence of a significant association between asbestos exposure and ovarian cancer mortality. While the possibility of misdiagnosis in earlier studies cannot be completely ruled out, recent findings suggest a robust correlation between asbestos exposure and ovarian cancer. This highlights the importance of sustained efforts to minimize asbestos exposure and protect public health.

• 대한안전경영과학회지
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• 제12권3호
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• pp.107-119
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• 2010

The aim of this study was to compare the carcinogen classification systems of developed countries or global organizations with domestic system under Industrial Safety and Health Act (ISHA). We selected the representative institutions which had carcinogen classification system such as International Agency for Research on Cancer (IARC), National Toxicological Program (NTP), Environmental Protection Agency (US-EPA), American Conference of Governmental Industrial Hygienists (ACGIH), and European Union (EU). We collected the carcinogen lists issued by 5 institutions, and merged by CAS number of each chemical with Microsoft Access 7.0. We found that confirmed human carcinogens, probable human carcinogens and possible human carcinogens were 34, 179, and 252, respectively. All of the institutions classified chemicals as 2 (NTP), 3 (EU) or 5 (IARC, ACGIH, US-EPA) categories based on the weight of scientific evidences for carcinogenicity and periodically updated the carcinogen list by regular procedure. However, a total of 90 chemicals could be classified as carcinogen under ISHA in Korea. There was no procedure or system which periodically update the carcinogen lists. In addition, the status of carcinogen classification according to regulation was confused. In conclusion, these findings suggest that the carcinogen classification and management system should be amended by consideration of systems of advanced institutions and the domestic regulation system.

• 월간산업보건
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• 통권361호
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• pp.19-25
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• 2018

• Safety and Health at Work
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• 제3권2호
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• pp.110-116
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• 2012

Establishing a causal relationship between factors at work and disease is difficult for occupational physicians and researchers. This paper seeks to provide arguments for the judgement of evidence of causality in observational studies that relate work factors to disease. I derived criteria for the judgement of evidence of causality from the following sources: the criteria list of Hill, the approach by Rothman, the methods used by International Agency for Research on Cancer (IARC), and methods used by epidemiologists. The criteria are applied to two cases of putative occupational diseases; breast cancer caused by shift work and aerotoxic syndrome. Only three of the Hill criteria can be applied to an actual study. Rothman stresses the importance of confounding and alternative explanations than the putative cause. IARC closely follows Hill, but they also incorporate other than epidemiological evidence. Applied to shift work and breast cancer, these results have found moderate evidence for a causal relationship, but applied to the aerotoxic syndrome, there is an absence of evidence of causality. There are no ready to use algorithms for judgement of evidence of causality. Criteria from different sources lead to similar results and can make a conclusion of causality more or less likely.

• Clinical and Experimental Pediatrics
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• 제63권11호
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• pp.422-428
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• 2020

In today's world, most children are exposed to various manmade electromagnetic fields (EMFs). EMFs are electromagnetic waves less than 300 GHz. A developing child's brain is vulnerable to electromagnetic radiation; thus, their caregivers' concerns about the health effects of EMFs are increasing. EMF exposure is divided into 2 categories: extremely low frequencies (ELFs; 3-3,000 Hz), involving high-voltage transmission lines and in-house wiring; and radiofrequencies (RFs; 30 kHz to 300 GHz), involving mobile phones, smart devices, base stations, WiFi, and 5G technologies. The biological effects of EMFs on humans include stimulation, thermal, and nonthermal, the latter of which is the least known. Among the various health issues related to EMFs, the most important issue is human carcinogenicity. According to the International Agency for Research on Cancer's (IARC's) evaluation of carcinogenic risks to humans, ELFs and RFs were evaluated as possible human carcinogens (Group 2B). However, the World Health Organization's (WHO's) view of EMFs remains undetermined. This article reviews the current knowledge of EMF exposure on humans, specifically children. EMF exposure sources, biological effects, current WHO and IARC opinions on carcinogenicity, and effects of EMF exposures on children will be discussed. As well-controlled EMF experiments in children are nearly impossible, scientific knowledge should be interpreted objectively. Precautionary approaches are recommended for children until the potential health effects of EMF are confirmed.