A Study on Classification and Management System for arcinogens

발암물질 분류 및 관리 체계 고찰

  • Choi, Sang-Jun (Department of Occupational Health, Catholic University of Daegu) ;
  • Lim, Kyong-Che (Department of Occupational Health, Catholic University of Daegu)
  • 최상준 (대구가톨릭대학교 산업보건학과) ;
  • 임경채 (대구가톨릭대학교 산업보건학과)
  • Received : 2010.05.31
  • Accepted : 2010.08.27
  • Published : 2010.09.30

Abstract

The aim of this study was to compare the carcinogen classification systems of developed countries or global organizations with domestic system under Industrial Safety and Health Act (ISHA). We selected the representative institutions which had carcinogen classification system such as International Agency for Research on Cancer (IARC), National Toxicological Program (NTP), Environmental Protection Agency (US-EPA), American Conference of Governmental Industrial Hygienists (ACGIH), and European Union (EU). We collected the carcinogen lists issued by 5 institutions, and merged by CAS number of each chemical with Microsoft Access 7.0. We found that confirmed human carcinogens, probable human carcinogens and possible human carcinogens were 34, 179, and 252, respectively. All of the institutions classified chemicals as 2 (NTP), 3 (EU) or 5 (IARC, ACGIH, US-EPA) categories based on the weight of scientific evidences for carcinogenicity and periodically updated the carcinogen list by regular procedure. However, a total of 90 chemicals could be classified as carcinogen under ISHA in Korea. There was no procedure or system which periodically update the carcinogen lists. In addition, the status of carcinogen classification according to regulation was confused. In conclusion, these findings suggest that the carcinogen classification and management system should be amended by consideration of systems of advanced institutions and the domestic regulation system.

Keywords

References

  1. International Agency for Research on Cancer (IARC). Cancer can be prevented too; research for prevention. In; Media center-IARC News. (2010). http://www.iarc.fr/en/media-centre/iarcnews/2010 /worldcancerday2010.pdf
  2. 보건복지가족부. 2009년도 국가암등록통계 결과 발표. 보도자료. 2009. 12. 22. (화) 조간. (2009)
  3. 보건복지가족부. 보건복지가족백서. (2007) :746-768
  4. Kraut A. Estimates of the extent of morbidity and mortality due to occupational diseases in Canada. American Journal of Industrial Medicine, 25 (1994) :267-278
  5. Leigh J, Markowitz S, Fahs M, Shin C, Landrigan P. Occupational injury and illness in the United States. Estimates of costs, morbidity, and mortality. Archives of Internal Medicine, 157 (1997) :1557-1568
  6. Steenland K, Loomis D, Shy C, Simonsen N . Review of occupational lung carcinogens. American Journal of Industrial Medicine, 29 (1996) :474-490
  7. Steenland K, Burnett C, Lalich N, Ward E, Hurrell J. Dying for work: The magnitude of US mortality from selected causes of death associated with occupation. American Journal of Industrial Medicine, 43(5) (2003) :461-482
  8. 박무인, 최종수, 최현묵, 장태일, 문익홍 등. 석면 취급의 직업력을 가진 환자에 발생한 흉막 악성중피종 1례. 대한내과학회지, 48(4) (1995) :526-529
  9. 강성규, 안연순, 정호근. 1990년대 한국의 직업성 암.대한산업의학회지, 13(4) (2001) :351-359
  10. 안연순, 강성규, 김광종. 최근 3년간(2001년-2003년) 직업병으로 요양승인된 질병의 특성. 대한산업의학회지, 16(2) (2004) :139-154
  11. International Agency for Research on Cancer . World Cancer Report 2008. (2008)
  12. International Agency for Research on Cancer. Agents reviewed by the IARC monographs volumes 1-100A. (2009)
  13. Euroup Union. Council Directive 67/548/EEC of 27 June 1967 on the approximation of laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances. (1967)
  14. National Toxicology Program. Report on carcinogens, eleventh edition. U.S. Department of Health and Human Services. (2005)
  15. U.S. Environmental Protection Agency. Integrated risk information system (IRIS). (2010) http:// www.epa/iris/index.html
  16. 노동부. 산업안전보건법시행규칙 별표 11의2. 유해인자의 분류기준. (2007)
  17. 노동부. 화학물질 및 물리적인자의 노출기준. 노동부고시 제2008-26호. (2008)
  18. 노동부. 산업보건기준에관한규칙 별표 7. 관리대상 유해물질의 종류. (2009)
  19. 환경부. 유해화학물질 관리법 시행령 별표 2. 유독물 및 관찰물질의 지정기준. (2009)
  20. Finnish Institute of Occupational Health. CAREX. International information system on occupational exposure to carcinogens. http://www.ttl.fi/Internet/ English/Organization/Collaboration/Carex/
  21. CAREX Canada. Surveilance of environmental & occupational exposures for cancer prevention. http://www.carexcanada.ca/en/