• 제목/요약/키워드: I3A

검색결과 33,241건 처리시간 0.071초

PRIME RADICALS OF SKEW LAURENT POLYNOMIAL RINGS

  • Han, Jun-Cheol
    • 대한수학회보
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    • 제42권3호
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    • pp.477-484
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    • 2005
  • Let R be a ring with an automorphism 17. An ideal [ of R is ($\sigma$-ideal of R if $\sigma$(I).= I. A proper ideal P of R is ($\sigma$-prime ideal of R if P is a $\sigma$-ideal of R and for $\sigma$-ideals I and J of R, IJ $\subseteq$ P implies that I $\subseteq$ P or J $\subseteq$ P. A proper ideal Q of R is $\sigma$-semiprime ideal of Q if Q is a $\sigma$-ideal and for a $\sigma$-ideal I of R, I$^{2}$ $\subseteq$ Q implies that I $\subseteq$ Q. The $\sigma$-prime radical is defined by the intersection of all $\sigma$-prime ideals of R and is denoted by P$_{(R). In this paper, the following results are obtained: (1) For a principal ideal domain R, P$_{(R) is the smallest $\sigma$-semiprime ideal of R; (2) For any ring R with an automorphism $\sigma$ and for a skew Laurent polynomial ring R[x, x$^{-1}$; $\sigma$], the prime radical of R[x, x$^{-1}$; $\sigma$] is equal to P$_{(R)[x, x$^{-1}$; $\sigma$ ].

체외성숙시간이 돼지 단위발생능에 미치는 영향

  • 임현선;김병정;이호준;최은주;윤종택
    • 한국발생생물학회:학술대회논문집
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    • 한국발생생물학회 2003년도 제3회 국제심포지움 및 학술대회
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    • pp.87-87
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    • 2003
  • 난자성숙 중 MPF활성은 MI 과 MII에서 최대로, MII로의 성숙 직후 난자를 핵이식에 이용하는 것은 핵과 세포질 사이의 reprogramming에의 효율을 높일 수 있을 것이다. 일반적으로 돼지의 IVF나 핵이식은 체외성숙후 44h에 이뤄지고 있다. 이는 aging을 낳을 수 있고 aging은 또한 발달능을 떨어뜨릴 수 있다. 따라서, 본 실험은 돼지의 체외성숙시간에 따른 체외성숙율과 단위발생후 체외발달율을 비교하여 최적의 체외성숙시간을 찾고자 실시하였다. 돼지 난포란을 10% pFF, 0.1mg/ml cysteine, 10IU/ml PMSG, 10IU/ml hCG, 10ng/ml EGF가 첨가된 TCM-199배양액에서 22, 30, 44시간 동안 배양하여 성숙을 유도하였다. 체외성숙이 야기된 난자는 난구세포를 제거한 후 전기자극(2.0kv/cm, $30 \mu s$) 후 5분 동안 TCM-199에서 세정하고 다시 4시간 동안 6-DMAP에서 배양된 후 4mg/ml BSA가 첨가된 NCSU-23에 넣어 $39^{\circ}C$, 5% $CO_2$배양기에서 각각 6-7일 동안 배양을 실시하였다. 체외성숙 22시간 성숙난자는 M I 44.3%(35/79)와 A I -T I 36.7%(29/79)로 81%가 M II로의 성숙에는 아직 미치지 못했다. 30시간 성숙난자는 46.3%(56/121)가 M II로 성숙하였고, M I과 A I -T I 은 각각 25.6%(31/121), 27 3%(33/121)이었다. 44시간 성숙난자는 78%(71/91)가 M II로 성숙하였고, M I 과 A I -T I 은 각각 12.1%(31/121), 7 7%(33/121)이었다. 단위발생율은 22시간에 난할율은 35.4%(75/137)이었고, 배반포 발달은 없었다. 30시간에 난할율은 51.8%(145/280)이었고, 배반포 발달율은 5.5%(8/145)이었다. 44시간에 난할율은 80.0%(244/306)이었고, 배반포 발달율은 14.3%(35/144)이었다. 본 연구결과 핵 및 세포질의 완전한 성숙은 44h에 이루어지고, 이에 따른 배발달율도 뒤따름을 알 수 있었다. 난자가 핵성숙의 완성에도 불구하고 완전한 활성을 위한 발달능은 갖지 못함을 알 수 있었으며, 질 좋은 배반포 생산을 위해 핵과 세포질 성숙의 synchronous가 중요하다 사료된다. 체외성숙을 위한 배양기술의 진전과 더불어 체외성숙 시간에 따른 세포질적인 기전에 대한 연구가 필요하다.

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돼지 유도만능줄기세포 유래 복제란의 특성 분석 (Developmental Characteristics of Cloned Embryos Reconstructed with Induced Pluripotent Stem Cells in Pigs)

  • 권대진;오재돈;박미령;황인설;박응우;황성수
    • 한국동물생명공학회지
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    • 제34권3호
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    • pp.232-239
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    • 2019
  • In general, cloned pigs have been produced using the somatic cell nuclear transfer (SCNT) technique with various types of somatic cells; however, the SCNT technique has disadvantages not only in its low efficiency but also in the development of abnormal clones. This study aimed to compare early embryonic development and quality of SCNT embryos with those of induced pluripotent stem cells (iPSCs) NT embryos (iPSC-NTs). Ear fibroblast cells were used as donor cells and iPSCs were generated from these cells by lentiviral transduction with human six factors (Oct4, Sox2, c-Myc, Nanog, Klf4 and Lin28). Blastocyst formation rate in iPSC-NT (23/258, 8.9%) was significantly lower than that in SCNT (46/175, 26.3%; p < 0.05). Total cell number in blastocysts was similar between two groups, but blastocysts in iPSC-NT had a lower number of apoptotic cells than in SCNT (2.0 ± 0.6 vs. 9.8 ± 2.9, p < 0.05). Quantitative PCR data showed that apoptosis-related genes (bax, caspase-3, and caspase-9) were highly expressed in SCNT than iPSC-NT (p < 0.05). Although an early development rate was low in iPSC-NT, the quality of cloned embryos from porcine iPSC was higher than that of embryos from somatic cells. Therefore, porcine iPSCs could be used as a preferable cell source to create a clone or transgenic animals by using the NT technique.

COMPACT INTERPOLATION FOR VECTORS IN TRIDIAGONAL ALGEBRA

  • Jo, Young-Soo;Kang, Joo-Ho
    • 대한수학회논문집
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    • 제18권3호
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    • pp.485-490
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    • 2003
  • Given vectors x and y in a Hilbert space, an interpolating operator is a bounded operator T such that Tx = y. An interpolating operator for n vectors satisfies the equation $Tx_i=y_i$ , for i, = 1,2,…,n. In this article, we investigate compact interpolation problems in tridiagonal algebra : Given vectors x and y in a Hilbert space, when is there a compact operator A in a tridiagonal algebra such that Ax = y?

Efficacy and safety of endoscopic submucosal dissection for colorectal dysplasia in patients with inflammatory bowel disease: a systematic review and meta-analysis

  • Talia F. Malik;Vaishnavi Sabesan;Babu P. Mohan;Asad Ur Rahman;Mohamed O. Othman;Peter V. Draganov;Gursimran S. Kochhar
    • Clinical Endoscopy
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    • 제57권3호
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    • pp.317-328
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    • 2024
  • Background/Aims: In this meta-analysis, we studied the safety and efficacy of endoscopic submucosal dissection (ESD) for colorectal dysplasia in patients with inflammatory bowel disease (IBD). Methods: Multiple databases were searched, and studies were retrieved based on pre-specified criteria until October 2022. The outcomes assessed were resection rates, procedural complications, local recurrence, metachronous tumors, and the need for surgery after ESD in IBD. Standard meta-analysis methods were followed using the random-effects model, and I2% was used to assess heterogeneity. Results: Twelve studies comprising 291 dysplastic lesions in 274 patients were included with a median follow-up of 25 months. The pooled en-bloc resection, R0 resection, and curative resection rates were 92.5% (95% confidence interval [CI], 87.9%-95.4%; I2=0%), 81.5% (95% CI, 72.5%-88%; I2=43%), and 48.9% (95% CI, 32.1%-65.9%; I2=87%), respectively. The local recurrence rate was 3.9% (95% CI, 2%-7.5%; I2=0%). The pooled rates of bleeding and perforation were 7.7% (95% CI, 4.5%-13%; I2=10%) and 5.3% (95% CI, 3.1%-8.9%; I2=0%), respectively. The rates of metachronous recurrence and additional surgery following ESD were 10% (95% CI, 5.2%-18.2%; I2=55%) and 13% (95% CI, 8.5%-19.3%; I2=54%), respectively. Conclusions: ESD is safe and effective for the resection of dysplastic lesions in IBD with an excellent pooled rate of en-bloc and R0 resection.

rBST 투여가 숫사슴의 혈액 내 IGF-I 함량에 미치는 영향 (Effect of Recombinant Bovine Somatotropin Injections on Deer Stag Plasma Insulin-like Growth Factor-I Profiles)

  • 신형태;최송환;정기환;안재남;백순용
    • Journal of Animal Science and Technology
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    • 제47권3호
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    • pp.439-446
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    • 2005
  • This study was conducted to elucidate the influence of recombinant bovine somatotropin (rBST) on the plasma IGF-I profiles in deer stags. Slow release rBST (250mg each) preparations were injected subcutaneously during the antler's non-growing period and growing period. It was observed that significant increases in the plasma IGF-I concentrations were occurred right after injections of the rBST irrespective of antler's non-growing period or growing period. When the rBST preparations were injected two times with one week interval during the antler's non-growing period, the mean level of IGF-I was found to be 2,920.7ng I mL, indicating that the IGF-I concentration increased up to 8.4-folds compared with a control. After two weeks from second shot, however, the IGF-I levels decreased to the level of the control. Similar results were also obtained with both a Sika and a Red deer during the antler's growing period. Increases in the IGF-I level of up to 5.6-folds with the Sika deer and 4.3-folds with the Red deer were found. Based on the present study, it is likely that the rBST may be used as a possible candidate for an antler's growth stimulating agent.

Mucosal Mast Cell Responses in the Small Intestine of C3H/HeN and BALB/c Mice Infected with Echinostoma hortense

  • Ryang, Yong-Suk;Im, Jee-Aee;Kim, In-Sik;Kim, Keun-Ha
    • 대한의생명과학회지
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    • 제9권3호
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    • pp.145-150
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    • 2003
  • In the intestinal mucosa, mast cells are thought to be responsible for the expulsion of parasites. We investigated the relationship of worm expulsion and mast cells in C3H/HeN and BALB/c mice infected with Echinostoma hortense. In addition, we examined whether the worm recovery rate was associated with the strain of mice, and whether a toluidine stain and immunohistochemistry using the c-kit antibody was effective in the detection of mast cells. In order to investigate the mucosal immune response of C3H/HeN and BALB/c mice, each mouse was infected orally with 30 E. hortense metacercariae. Then, the number of mucosal mast cells and worm recovery rates was observed in experimentally infected mouse strains between 1 week and 8 weeks post infection (PI). Mucosal mast cells were increased in 3 weeks P.I. in C3H/HeN and BALB/c mice. On the other hand, only mucosal goblet cells and worm recovery rates correlated in C3H/HeN mice (P=0.0482). Worm recoveries in C3H/HeN mice were 65.7$\pm$5.6, 53.3$\pm$5.4 and 6.7$\pm$0.6 in week 1, 2, and 3 P.I. and strongly decreased in week 3 P.I. Worm recoveries in BALB/c mice were 23.0$\pm$2.5, 10.0$\pm$1.0, and 6.7$\pm$0.6% in week 1, 2, and 3 P.I. and gradually decreased from week 1 P.I. to week 3 P.I. Worm recoveries in C3H/HeN mice were significantly higher than in BALB/c mice (P<0.00l). The number of mast cells in C3H/HeN and BALB/c mice using the anti-c-kit antibody reached to a peak in week 3 P.I. and recovered as normal level in week 5 P.I. and 6 P.I. The number in E. hortense-infected C3H/HeN mice (P=0.0015) was higher than in E. hortense-infected BALB/c mice (P=0.01) compared with the control group. There were significant differences in the number of mast cells among regions of the intestine in in C3H/HeN mice (P<0.05) but not in BALB/c mice (P>0.05). Immunohistochemistry using the anti-c-kit antibody was significant method as an examination of the number of mast cells (P=0.0002). In conclusion, the present study demonstrated that mast cells play an important role in worm recovery, and immunohistochemistry using the anti-c-kit antibody was superior to toluidine stain as an examination of mast cells.

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면직물의 건식전사날염에 관한 연구 (Studies on the Transfer Printing of Cotton Fabrics)

  • 황종호;이석영;조환
    • 한국염색가공학회지
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    • 제7권3호
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    • pp.31-37
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    • 1995
  • Effects of glycol pretreatment conditions such as concentration and molecular weight of glycols and dye types of different constitutions on the degree of transfer were investigated when transfer printed onto the cotton fabric with disperse dyestuffs. Obtained results are as follows ; 1. Although the degree of transfer increases linearly with temperature a time, above a certain critical point, they show decremental aspects for both of C.I. Disperse Orange 3 and C.I. Diperse Violet 1. 2. Degree of transfer increases with molecular weight of glycols, but PEG 200 which has a moleular weight 200 and boiling point of 300$^{\circ}C$ is more effcient than that of lower molecular weight. 3. Degree of tansfer for the C.I. Disperse Orange 3 having constitution of azo benzene type is somewhat higher than that of C.I. Disperse Violet 1 of amino anthraquinone.

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스마트 기기의 효율적인 I/O를 위한 플래시 파일 시스템 성능 분석 (Performance Analysis of Flash File System for the Efficient I/O on Smart Device)

  • 정경호;김용환;김상진;정영석;김성수
    • 대한임베디드공학회논문지
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    • 제10권3호
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    • pp.171-178
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    • 2015
  • Recently NAND flash memory has been found to be the primary cause of low performance in the smart device. NAND flash memory is different from each other the execution time of I/O operations that flash file system is required. Therefore, it is necessary to compare and analyze the flash file system I/O performance for the efficient I/O on smart device. In this paper, it was tested and analyzing the I/O performance of the YAFFS2, JFFS2, UBIFS. Experimental results most read I/O performance is good, but the writing I/O performance is not good. For UBIFS, showed a more good I/O performance compared to other flash file system.

C-H…H-Fe Dihydrogen 결합: $trans-[FeH(NCS(i-Pr)-S)(dppe)_2]I$ 착물의 합성 및 구조 (C-H…H-Fe Dihydrogen Bonding: Synthesis and Structure of $trans-[FeH(NCS(i-Pr)-S)(dppe)_2]I$ $(dppe=Ph_2PCH_2Ch_2PPh_2)$)

  • 이지화;이순원
    • 한국결정학회지
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    • 제11권1호
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    • pp.10-15
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    • 2000
  • Compound trans-[FeH(NCS(i-Pr)-S)(dppe)₂](1) reacted with isopropyl iodide (i-PrI) to give an Fe(II)-organic isothiocyanide complex, trans-[FeH(NCS(i-Pr)-S)(dppe)₂]I (2). Compound 2 was structurally characterized, in which the hydride ligand appears to be involved in the "dihydrogen" bonding, M-H…H-C. Crystallographic data for 2: monoclinic space group P2₁/n, a=13.490(2)Å, b=17.269(3)Å, c=21.384(3)Å, β=90.682(7)°, Z=4, R(wR₂)=0.0348(0.0894).

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