• 제목/요약/키워드: I-P Curve

검색결과 303건 처리시간 0.034초

근치적 수술 후 재발한 I, II 병기 비소세포폐암의 임상양상 및 조직학적 유형의 차이 비교 (Clinicopathologic Characteristics of Recurrence after Curative-intent Surgical Therapy of Non-small Cell Lung Cancer)

  • 송성헌;손장원;곽현정;김사일;이승호;김상헌;김태형;윤호주;신동호;박성수
    • Tuberculosis and Respiratory Diseases
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    • 제70권4호
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    • pp.330-337
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    • 2011
  • Background: The clinicopathologic characteristics of patients with non-small cell lung cancer (NSCLC) have been changing. Recently, Positron emission tomography-computed tomography (PET-CT) has usually been used for diagnosis, follow-up to treatment and surveillance of NSCLC. We studied the pattern of recurrence and prognosis in patients who underwent complete resection for NSCLC according to histologic subtype. Methods: All patients who underwent complete resection for pathological stage I or II NSCLC between January 2005 and June 2009 were identified and clinical records were reviewed retrospectively, especially the histologic subtype. Results: Recurrences were identified in 50 of 112 patients who had complete resection of an NSCLC. Sites of recurrence were locoregional in 15 (30%), locoregional and distant in 20 (40%), and distant in 15 (30%). Also, sites of recurrence were intra-thoracic in 29 (58%), extrathoracic and intra-thoracic recurrence in 15 (30%), and extrathoracic in 6 (12%). In locoregional recurrence, there was 37% recurrence for non-squamous cell carcinoma (non-SQC) and 25% for squamous cell carcinoma (SQC). In distant recurrence, there was 39% recurrence for non-SQC and 18% for SQC. Locoregional recurrence in the bronchial stump was more common in SQC than non-SQC (14% vs. 45%, p=0.025). Prognosis of recurrence was not influenced by histologic subtype and the recurrence-free survival curve showed that the non-SQC group did not differ from the SQC group according to stage. Conclusion: The prognosis for recurrence does not seem to be influenced by histologic types, but locoregional recurrence in the bronchial stump seems to be more common in SQC than non-SQC in completely resected stage I and II NSCLC.

골격성 III급 부정교합 환자에서 술전 교정전 예측치와 교정 후 실측치의 차이에 관한 연구 (A study on the preorthodontic prediction values versus the actual postorthodontic values in Class III surgery patients)

  • 황충주;권희정
    • 대한치과교정학회지
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    • 제33권1호
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    • pp.1-9
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    • 2003
  • 본 연구에서는, 술전 교정전 예측치와 교정 후 실측치 사이에 나타나는 오차의 크기와 정확성 및 어떠한 요소가 그러한 결과에 영향을 미치는지에 대해 평가하고자 하였다. 연세대학교 치과병원 교정과에서 골격성 III급 부정교합으로 진단되어 술전 교정치료 및 양악수술을 받은 환자 가운데 조건에 부합되는 45명(남자 17명, 여자 28명)을 선별하여, 초진 상태를 T1, 교정 치료전 예측치를 T2, 술전 교정후를 T3로 정의하고 각각의 계측치를 수평과 수직좌표로 나누어 측정하였다. 또한 환자의 어떠한 진단적 요소가 술전교정의 예측치와 실측치 사이의 차이에 영향을 미치는지 알아보기 위해 연구대상을 arch length discrepancy (ALD), 상$\cdot$하악 전치의 치축(U1 to SN, IMPA), curve of Spee(COS), 발치 여부, 발치한 치아의 종류 등에 의해 여러 군으로 분류하여 유의성을 평가하였으며 다음과 같은 결과를 얻었다. 1. U6mbc, L1x의 수평 좌표와 U1i, U1x, W6me, U6mbc, L6mbc의 수직 좌표에서 예측한 위치와 수술직전의 실제 위치의 차이가 유의성(p<0.05) 있게 나타났다. 2. 예측의 정확성은 수평적인 차이의 예측에 있어서 수직적인 차이의 예측에 비해 상대적으로 높게 나타났다. 3. 하악에서보다 상악의 많은 계측점에서 예측치와 실측치 사이의 유의한 차이(p<0.05)가 관찰되었다. 4. 상악의 경우 발치 여부 및 발치한 치아의 종류, ALD의 양에 따라 상악 전치와 제1대구치 위치의 예측에 유의한 차이(p<0.05)를 보였으며, 하악의 경우에는 ALD의 양과 IMPA에 따라 하악 전치와 제1대구치의 위치의 예측에 유의한 차이(p<0.05)를 나타냈다. 이번 연구에서 얻은 결과를 통하여 술전 교정전 예측치와 실측치 사이의 오차의 정도와 그것에 영향을 미치는 요소들을 분석하고 회귀 계수를 구함으로써, 악교정 수술을 동반한 교정 환자의 치료 계획 시 예측의 정확성을 높일 수 있을 것으로 생각된다. 또한 수직적인 예측에 있어서는 앞으로 더 많은 연구가 이루어져야 할 것으로 생각된다.

강구조물(鋼構造物)의 용접연결부(鎔接連結部)의 피로강도(疲勞强度)에 관한 연구(研究)(II) (A Study on the Fatigue Strength of the Welded Joints in Steel Structures(II))

  • 박제선;정영화;장동일
    • 대한토목학회논문집
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    • 제6권1호
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    • pp.1-11
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    • 1986
  • 강구조물(鋼構造物)의 girder중(中) 중요형식(重要形式)인 판항(板桁)에서 덮개판(板) 및 수직보강재(垂直補剛材)와 판항(板桁)이나 상자항(箱子桁)의 격점부(格點部)에 사용도는 연결판(連結板) 등의 용접연결부(鎔接連結部)를 포함하는 실물(實物)을 modeling하여 직접 피로시험(疲勞試驗)을 행하지 않고서도 계산에 의하여 S-N 선도(線圖)를 그려서 피로강도(疲勞强度)를 추정(推定)할 수 있는 계산식 및 program을 정립하였다. 또, 실물시험편(實物試驗片)에 대한 피로시험(疲勞試驗)을 행하여 계산에 의한 S-N 선도상(線圖上)에 plot하여 서로 비교 검토하였다. 이로써 다음과 같은 결과를 얻었다. 계산에 의한 피로강도(疲勞强度)가 실험(實驗)에 의한 실제 피로강도(疲勞强度)보다 다소 낮게 나타났다. 계산에 의한 방법은 초기균열(初忌龜裂) $a_i$가 발생한 다음부터 파단시(破斷時)까지의 피로수명(疲勞壽命) $N_p$에 대한 것임에 비해 실험(實驗)에 의한 것은 초기균열(初忌龜裂) $a_i$의 발생수명(發生壽命) $N_c$까지를 포함한 총(總) 피로수명(疲勞壽命) $N=N_c+N_p$에 대한 것이므로 오히려 당연한 결과라 생각된다. 그 차이가 그다지 크지 않으며, 구조물(構造物)의 안전성(安全性)을 생각할 때 계산(計算)에 의한 결과가 안전측(安全側)에 해당하므로 실제 구조물(構造物)의 피로설계(疲勞設計) 시(時) 그대로 적용하여도 무방할 것으로 생각된다. 참고로 저강도강(低强度鋼)인 SS 41 시험편(試驗片)을 각 경우 3개씩 제작하여 같은 피로시험(疲勞試驗)을 행하여 비교해 보았다. 덮개판(板)의 경우 시험최대응력(試驗最大應力) $14kg/mm^2$ 정도 이상(以上)에서 서서히, 수직보강재(垂直補剛材)의 경우 실험최대응력(實驗最大應力) $31kg/mm^2$ 정도 이하(以下)에서 급격(急激)히, 고강도강(高强度鋼)인 SWS 50 시험편(試驗片)의 경우보다 피로강도(疲勞强度)가 더 커진 경향을 나타내고 있다. 이는 저강도강(低强度鋼)에서 피로강도(疲勞强度)가 낮을 것이라는 상식적(常識的)인 기대와는 다른 특징(特徵)이지만 시험편(試驗片) 3개씩만의 결과이므로 확정적(確定的)인 결론이라고 단언(斷言)할 수는 없겠으며, 앞으로 더 많은 실험(實驗)을 행하여 확인해 보아야 할 것이라 생각된다.

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Comparison between different cone-beam computed tomography devices in the detection of mechanically simulated peri-implant bone defects

  • Kim, Jun Ho;Abdala-Junior, Reinaldo;Munhoz, Luciana;Cortes, Arthur Rodriguez Gonzalez;Watanabe, Plauto Christopher Aranha;Costa, Claudio;Arita, Emiko Saito
    • Imaging Science in Dentistry
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    • 제50권2호
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    • pp.133-139
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    • 2020
  • Purpose: This study compared 2 cone-beam computed tomography (CBCT) systems in the detection of mechanically simulated peri-implant buccal bone defects in dry human mandibles. Materials and Methods: Twenty-four implants were placed in 7 dry human mandibles. Peri-implant bone defects were created in the buccal plates of 16 implants using spherical burs. All mandibles were scanned using 2 CBCT systems with their commonly used acquisition protocols: i-CAT Gendex CB-500 (Imaging Sciences, Hatfield, PA, USA; field of view [FOV], 8 cm×8 cm; voxel size, 0.125 mm; 120 kVp; 5 mA; 23 s) and Orthopantomograph OP300 (Intrumentarium, Tuusula, Finland; FOV, 6 cm×8 cm; voxel size, 0.085 mm; 90 kVp; 6.3 mA; 13 s). Two oral and maxillofacial radiologists assessed the CBCT images for the presence of a defect and measured the depth of the bone defects. Diagnostic performance was compared in terms of the area under the curve (AUC), accuracy, sensitivity, specificity, and intraclass correlation coefficient. Results: High intraobserver and interobserver agreement was found (P<0.05). The OP300 showed slightly better diagnostic performance and higher detection rates than the CB-500 (AUC, 0.56±0.03), with a mean accuracy of 75.0%, sensitivity of 81.2%, and specificity of 62.5%. Higher contrast was observed with the CB-500, whereas the OP300 formed more artifacts. Conclusion: Within the limitations of this study, the present results suggest that the choice of CBCT systems with their respective commonly used acquisition protocols does not significantly affect diagnostic performance in detecting and measuring buccal peri-implant bone loss.

간척지 갈대의 영양생장과 지상부 모듈의 개체군 동태 (Clonal Growth and Shoot Modules Dynamics of Phragmites longivalvis in a Reclaimed Land)

  • Choung, Yeon-Sook;Kim, Joon-Ho
    • The Korean Journal of Ecology
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    • 제12권3호
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    • pp.171-182
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    • 1989
  • The structure, clonal grwoth, shoot modules dynamics and rhizome respiratory rate of the Phragmites longivalvis circular patch were studied in a 15-year-old reclaimed land on Mado of the western Korea for two growing seasons. Clonal growth by P. longivalvis resulted in subpopulations of shoot modules which may be separated into pioneer, mature and senile growth phase. The radial growth of circular patch was 208 cm per a year. The shoot phytomass, shoot height and spike frequency were the lowest in the senile phase, and were the highest in the mature phase. The maximum shoot phytomass of pioneer, mature and senile phase in August was 347, 536 and 195g/$\m^2$ for the first year, and 609, 748 and 248g/$\m^2$ for the second year, respectively. The birth rates of shoot modules were the highest during the early spring. Of all modules, the percemtage of spring cohort of pioneer, mature and senile growth phase were 52, 82 and 70% for the first year, and 83, 88 and 85% for the second year, respectively. The flowering shoots were only derived from spring cohorts. The death rates of shoot modules of the pioneer and mature phase were the highest in October. The module is an annual semelparous plant though the genet is a perennial iteroparous plant. Their survivorship curve was negatively (Deevey type I). The density of shoot modules of the pioneer, mature and senile growth phase increased as much as 4.0, 1.6 and 2.3 times for one year, respectively. The respiratory rate was the highest in the lowest in the senile growth phase.

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아선약의 염색성과 기능성(제1보) -아선약 색소의 특성과 면섬유에 대한 염색성- (Dyeability and functionality of Catechu(Part I) -Characteristics of Catechu and Dyeing properties of Cotton-)

  • 남기연;이정순
    • 한국생활과학회지
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    • 제19권4호
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    • pp.699-707
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    • 2010
  • Catechu is widely used as in natural dyeing as well as in various medicines and tannage. This study investigated the dyeing properties and functionality of Catechu through a series of dyeing experiments using cotton fabric. It was shown that the absorbance of Catechu solution has two peaks at 220nm and 280nm. Thus, it can be concluded that the color constituent of Catechu is a catechol tannin and color tone is YR. The dyeability of Catechu increases as the concentration of the dye is increased. Its variation was shown to be similar to the isothermal absorption curve of the Freundlich. As dyeing time was increases, the dyeability did not change significantly after the 30 minute mark was passed. At high temperatures the dyeability was shown to increase. As the dyeing temperature was increased the color of dyeing fabrics changes from Y and YR to R. Experiments with pre-mordanting method showed that various colors can be obtained using Catechu. Cotton is effective in using K, Cu, Fe mordants, and the dyeability was shown to be improved with low pH. Both washing fastness and light fastness were shown to be low. However, the fabric color gradually changed to red was due to mailard reaction of catechol tannin causing by repeated washing and sunlight. The ultraviolet-cut ability was improved for cotton fabric dyed with Catechu. Also, dyed fabric with Catechu showed very good antimicrobial abilities at 99.9%.

A Model Approach to Calculate Cancer Prevalence From 5 Year Survival Data for Selected Cancer Sites in India

  • Takiar, Ramnath;Jayant, Kasturi
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권11호
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    • pp.6899-6903
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    • 2013
  • Background: Prevalence is a statistic of primary interest in public health. In the absence of good follow-up facilities, it is difficult to assess the complete prevalence of cancer for a given registry area. Objective: An attempt was here made to arrive at complete prevalence including limited duration prevalence with respect to selected sites of cancer for India by fitting appropriate models to 1, 3 and 5 years cancer survival data available for selected population-based registries. Materials and Methods: Survival data, available for the registries of Bhopal, Chennai, Karunagappally, and Mumbai was pooled to generate survival for breast, cervix, ovary, lung, stomach and mouth cancers. With the available data on survival for 1, 3 and 5 years, a model was fitted and the survival curve was extended beyond 5 years (up to 35 years) for each of the selected sites. This helped in generation of survival proportions by single year and thereby survival of cancer cases. With the help of survival proportions available year-wise and the incidence, prevalence figures were arrived for selected cancer sites and for selected periods. Results: The prevalence to incidence ratio (PI ratio) stabilized after a certain duration for all the cancer sites showing that from the knowledge of incidence, the prevalence can be calculated. The stabilized P/I ratios for the cancer sites of breast, cervix, ovary, stomach, lung, mouth and for life time was observed to be 4.90, 5.33, 2.75, 1.40, 1.37, 4.04 and 3.42 respectively. Conclusions: The validity of the model approach to calculate prevalence could be demonstrated with the help of survival data of Barshi registry for cervix cancer, available for the period 1988-2006.

구강세균에 대한 구름버섯 추출물의 항균효과 (Antimicrobial activities of various extracts of Coriolus versicolor against oral bacteria)

  • 김별이;임근옥;한소라;김기화;오태진
    • 한국치위생학회지
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    • 제17권1호
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    • pp.111-122
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    • 2017
  • Objectives: Coriolus versicolor is an edible mushroom with physiological activities that has been used in traditional medicine. The aim of this study was to investigate the antimicrobial activity of extracts obtained from Coriolus versicolor against oral pathogens. Methods: The antimicrobial activities of various extracts of Coriolus versicolor were examined by disc diffusion assay, and minimum inhibitory concentration (MIC) of these extracts were also was determined by broth dilution method. The growth inhibition effect of extracts was measured at 600 nm for 12 hrs against Streptococcus ratti, Streptococcus criceti, Aggregati--bacter actinomycetemcomitans, Actinomyces viscosus, and Actinomyces israelii. Results: Coriolus versicolor extracts showed antimicrobial activities against all nine oral pathogens through disc diffusion assay. The ethanol extract and ethyl acetate extract differed significantly compared with acetone extract against Streptococcus ratti, Streptococcus criceti, Actinomyces viscosus, Actinomyces israelii and Aggregatibacter actinomycetemcomitans (p<0.05). These extracts exhibited MIC ranges of 2.63 to >10.50 mg/ml against the tested bacteria. The ethanol extract from Coriolus versicolor showed lower MIC values of 2.63 to 5.25 mg/ml. According to the obtained growth curve, the extracts of Coriolus versicolor were more effective against Actinomyces viscosus. Conclusions: The acetone, ethanol, and ethyl acetate extracts from Coriolus versicolor showed antimicrobial activities against Streptococcus mutans, Staphylococcus aureus, Streptococcus sanguinis, Streptococcus sobrinus, Streptococcus ratti, Streptococcus criceti, Aggregatibacter actinomycetemcomitans, Actinomyces viscosus, and Actinomyces israeli.i Therefore, they could be considered as natural oral antimicrobial agents against oral pathogens.

견관절 만성 충돌 증후군의 관절경적 견봉하 감압술 (Arthroscopic Subacromial Decompression for Chronic Impingement)

  • 이광원;박종현;최원식
    • Clinics in Shoulder and Elbow
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    • 제1권2호
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    • pp.160-166
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    • 1998
  • The purpose of this study was to assess the results of arthroscopic subacromial decompression in patients with chronic impingement and to evaluate the results according to the rotator cuff pathology. We evaluated the clinical results of treatment for chronic impingement syndrome in 28 patients from Feb 1996 to Feb 1997. There were twenty men and eight women in age from 24 to 72 years (mean age 51) with dominant arm involvement in sixteen patients. Follow up evaluations averaged 15(range 12-24)months. The average duration of symptoms were 15(range 6­60)months. The final diagnoses which were based on the physical examination, plain radiographs and arthroscopic findings, were stage II impingement in 16 patients and stage ill impingement in 12 patients. We excluded the patients with acromioclavicular arthritis or glenohumeral instability in this study. All patients were managed non-operatively a minimum of six months. During the operation we performed contouring and smoothing the acromial undersurface and only resecting of the anterolateral band of the coracoacromial ligament. The clinical results were quantitated using UCLA shoulder rating score. Satisfactory results were obtained in 23(80%) patients. Unsatisfactory results were obtained in 5(18%) patients with posterior cuff tear. The average UCLA pain score showed significant improvement from 2.8(constant pain) to 7.2(present during heavy activities) at final follow up. The function and active forward flexion scores also increased from their preoperative value. There was no significant differences according to the surface and severity of tear and NeeI' stage (P>0.05). These results compared favorably with those reported following open acromioplasty. While arthroscopic subacromial decompression is a demanding technique with a learning curve, it is a reliable treatment for chronic impingement syndrome. A less aggressive approach to subacromial decompression and preserving the posteromedial band of the coracoacromialligament does not appear to compromise results.

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Period Study and Light Curve Synthesis of BD Andromedae

  • 김천휘;송미화;윤요나;한원용;최영준
    • 천문학회보
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    • 제36권2호
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    • pp.141.1-141.1
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    • 2011
  • New CCD BVR light curves of BD And are presented. Our light curves with nearly equal depths for both primary and secondary eclipses show well-defined photometric waves outside eclipse for all of BVR bandpasses. The orbital period is greatly revised as $0.^d92580519$ which is twice longer than that known previously. Sixteen timings from our observations and thirteen ones from the SuperWASP measurements were calculated. All available timings over 76 years, including ours, were analyzed to figure out the dynamical behavior of the system. It was found that the recent CCD O-C residuals varied in a cyclical way with a period of $9.^y18$ and a semi-amplitude of $0.^d0046$. The secondary period of $9.^y18$ is the most shortest one among those which have been ever found in the short period RS CVn binary stars. The periodic variation most likely arises from the light-travel time effect due to a low-mass ($m_3{\sim}0.88\;M_{\odot}$) tertiary companion moving in an orbit with an large eccentricity ($e_3$=0.70) and a low inclination ($i_3{\sim}28^{\circ}$). The Applegate mechanism could not operate properly in both components because the model parameters require too much large luminosity changes of ${\Delta}L/L_{p,s}$ > 10. The new light curves were synthesized using the 2003 version of Wilson-Divinney code. It was found useful to model two huge spots on the surface of the hotter star and a third-light in order to minimize the residuals from the observations. Astronomical basic parameters were deduced from our photometric solution.

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