• Title/Summary/Keyword: Hye-seok

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동전기 토양세척폐액 처리기술개발

  • Kim, Gi-Hong;Kim, Gye-Nam;Son, Dong-Bin;Park, Hye-Min;Kim, Wan-Seok;Lee, Geon-U;Lee, Gi-Won;Mun, Je-Gwon;Kim, Byeong-Tae
    • Proceedings of the Korean Radioactive Waste Society Conference
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    • 2011.05a
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    • pp.265-266
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    • 2011
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Fucoidan Promotes the Reconstruction of Skin Equivalents

  • Song, Yu Seok;Li, Hailan;Balcos, Marie Carmel;Yun, Hye-Young;Baek, Kwang Jin;Kwon, Nyoun Soo;Choi, Hye-Ryung;Park, Kyoung-Chan;Kim, Dong-Seok
    • The Korean Journal of Physiology and Pharmacology
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    • v.18 no.4
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    • pp.327-331
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    • 2014
  • In this study we investigated the effects of fucoidan on the proliferation of fibroblasts and the reconstruction of a skin equivalent (SE). Fucoidan significantly stimulated the proliferation of CCD-25Sk human fibroblasts and Western blot analysis demonstrated that fucoidan markedly increased the expression of cyclin D1 and decreased the expression of p27. Fucoidan was used to reconstruct SE. Immunohistochemical staining showed that the addition of fucoidan to dermal equivalents increased expression of proliferating cell nuclear antigen (PCNA) and p63. In addition, expression of ${\alpha}6$-integrin was significantly increased by fucoidan, whereas expression of ${\beta}1$-integrin, type 1 collagen, elastin, fibronectin did not markedly change. These results suggest that fucoidan has positive effects on epidermal reconstruction and will therefore be beneficial in the reconstruction of SE.

Psychiatric understanding and treatment of patients with amputations

  • Jo, So-Hye;Kang, Suk-Hun;Seo, Wan-Seok;Koo, Bon-Hoon;Kim, Hye-Geum;Yun, Seok-Ho
    • Journal of Yeungnam Medical Science
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    • v.38 no.3
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    • pp.194-201
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    • 2021
  • Amputation changes the lives of patients and their families. Consequently, the patient must adapt to altered body function and image. During this adaptation process, psychological problems, such as depression, anxiety, and posttraumatic stress disorder, can occur. The psychological difficulties of patients with amputation are often accepted as normal responses that are often poorly recognized by patients, family members, and their primary physicians. Psychological problems can interfere with rehabilitation and cause additional psychosocial problems. Therefore, their early detection and treatment are important. A multidisciplinary team approach, including mental health professionals, is ideal for comprehensive and biopsychosocial management. Mental health professionals could help patients set realistic goals and use adaptive coping styles. Psychiatric approaches should consider the physical, cognitive, psychological, social, and spiritual functions and social support systems before and after amputation. The abilities and limitations of physical, cognitive, psychological, and social functions should also be considered. To improve the patient's adaptation, psychological interventions such as short-term psychotherapy, cognitive behavioral therapy, mindfulness meditation, biofeedback, and group psychotherapy can be helpful.