• Clinical and Experimental Pediatrics
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• v.46 no.1
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• pp.91-94
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• 2003

Raine syndrome was described as an unknown syndrome in 1989. It is characterized by severe craniofacial anomalies with microcephaly, hypoplastic nose, depressed nasal bridge, exophthamos/protosis, gum hypertrophy, cleft palate, low-set ears, small mandible, narrow chest, wide cranial sutures and choanal atresia or stenosis, by generalized osteosclerosis with subperiosteal thickening of ribs, clavicles and diaphysis of long bones, and by intracranial calcifications in the particularly periventricular area. It undergoes an autosomal recessive inheritance. Twelve cases of Raine syndrome have been reported in the literature. However, a case of Raine syndrome in Korea has not been reported yet. Therefore, we describe a female newborn with Raine syndrome with a brief review of the literatures.

• Journal of Korea Multimedia Society
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• v.11 no.8
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• pp.1059-1071
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• 2008

Users in ubiquitous computing environment can easily access and use a multitude of devices and services anywhere and anytime. The key technology to realize this scenario is the method to intuitively provide proper user interfaces for each device and service. Previous attempts simply provided a designated user interface for each device and service or provided an abstract user interface to control common functions of different services. To select a target appliance, either user directly specified the target device or depended on sensors such as RFID tags and readers limiting the applicable scenarios. In this paper, we present UbiController which uniquely uses camera on the mobile device to recognize markers of appliances to acquire user interface for controlling task. UbiController aims to provide automatic discovery of multiple services in the smart home environment, support traditional GUI and novel camera-based recognition method as well as intuitive interaction methods for users. In this paper, we show experiments on the performance of UbiController's discovery and recognition methods and user feedback on interaction methods from a user study.

• IMMUNE NETWORK
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• v.10 no.6
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• pp.219-229
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• 2010

Background: N-myc downstream regulated gene 2 (NDRG2) is a member of the NDRG gene family. Our previous report indicated a possible role for NDRG2 in regulating the cytokine, interleukin-10 (IL-10), which is an important immunosuppressive cytokine. Several pathways, including p38-MAPK, NF-${\kappa}B$, and JAK/STAT, are used for IL-10 production, and the JAK/STAT pathway can be inhibited in a negative feedback loop by the inducible protein, SOCS3. In the present study, we investigated the effect of NDRG2 gene expression on IL-10 signaling pathway that is modulated via SOCS3 and STAT3. Methods: We generated NDRG2-overexpressing U937 cell line (U937-NDRG2) and treated the cells with PMA to investigate the role of NDRG2 in IL-10 production. U937 cells were also transfected with SOCS3- or NDRG2-specific siRNAs to examine whether the knockdown of SOCS3 or NDRG2 influenced IL-10 expression. Lastly, STAT3 and SOCS3 induction was measured to identify the signaling pathway that was associated with IL-10 production. Results: RT-PCR and ELISA assays showed that IL-10 was increased in U937-mock cells upon stimulation with PMA, but IL-10 was inhibited by overexpression NDRG2. After PMA treatment, STAT3 phosphorylation was decreased in a time-dependent manner in U937-mock cells, whereas it was maintained in U937-NDRG2 cells. SOCS3 was markedly reduced in U937-NDRG2 cells compared with U937-mock cells. IL-10 production after PMA stimulation was reduced in U937 cells when SOCS3 was inhibited, but this effect was less severe when NDRG2 was inhibited. Conclusion: NDRG2 expression modulates SOCS3 and STAT3 activity, eventually leading to the inhibition of IL-10 production.

• Journal of Acupuncture Research
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• v.26 no.3
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• pp.59-65
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• 2009

Objectives : This survey was done in order to find out how Korean medical doctors derive pattern identification for acupuncture prescriptions in treating knee pain in real clinical practice. Methods : The survey questionnaire was developed by the committee of experts who major in acupuncture & moxibustion or statistics for acupuncture clinical trial protocol development. The questionnaires were distributed via e-mail to 75 members of Korean Acupuncture & moxibustion society from March 26th to April 14th in 2009. 57 members completed answers, and the computerized data were analyzed by SPSS 17.0 statistical program. Results : 1.54 Korean medical doctors selected meridian pattern identification based on the course of the meridians(52.5%), visceral pattern identification(27.1%), pattern identification based on cause of disease(8.5%) as the most commonly used pattern identification methods for acupuncture prescription when treating knee pain patients in real clinical practice. 2. In meridian pattern identification based on the course of the meridians, liver meridian of the medial knee region(13.2%), bladder meridian of the posterior knee region(12.0%), spleen meridian of the lateral knee region(11.7%), stomach meridian of the anterior knee region(9.8%) and kidney meridian of the medial knee region(8.6%) were selected. 3. In visceral pattern identification, blood stasis of sinews due to liver and kidney deficiency(5.3%), damp joint with yang deficiency of liver and kidney(4.9%), kidney qi deficiency with congealing cold(4.5%), yin deficiency of liver and kidney(4.1%) were selected. Conclusions : In our e-mail survey, Korean medical doctors answered that Meridian Pattern Identification based on the course of the meridians is the most often used diagnosis method. Visceral pattern identification, pattern identification based on cause of disease, pattern identification based on symptom and pattern identification based on qi-blood-yin-yang theory in order of frequency used, were selected for knee pain diagnosis in real clinical practice.

• Journal of the Korean Institute of Landscape Architecture
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• v.40 no.6
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• pp.35-46
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• 2012

This study attempts to specifically analyze green volume and scenery characteristics by classifying the streets in Seoul and suggest improvements accordingly. The subject streets for research were limited to those that have high occupancy ratio and are wide enough to have a big potential in improving green volume. In terms of green volume and scenery according to the types of streets, Platanus occidentalis and Ginkgo biloba were most common regardless of the street type, and the green ratio was 51.6% in residential areas, 50.4% in commercial areas, and 43.7% in business areas. Apart from the residential area, there was almost no green areas, and the ratio of green coverage was 71.0% in business areas, 64.0% in green areas, 37.3% in residential areas, and 36.2% in commercial areas, while the green volume coefficient was $1.9m^3/m^2$ on average. Based on the study results, it was set as a goal to provide the residential areas with a green community space and flowering trees throughout the year for scenery, and commercial areas with flowering trees and maples to emphasize the stores' image while not interfering with service and walking. For business areas, the goals were to improve green ratio and create streets that suit the urban image, and to set up spaces to provide habitat for wild animals with multi-layer planting and link to surrounding forests.

• Korean Journal of Biological Psychiatry
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• v.20 no.4
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• pp.166-178
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• 2013

Objectives Alteration of epigenetic effects of testosterone during early development was suggested as an ancillary mechanism for the genesis of schizophrenia. EEG coherence was thought to be a marker for cerebral laterality of which important determinant was testosterone during early development. We studied sex-related differences of EEG coherences between patients with schizophrenia and controls to examine the sex effects in the genesis of schizophrenia. Methods EEG was recorded in 35 patients with schizophrenia and 46 healthy controls in the eyes closed resting state. Pair-wise EEG coherences were calculated over delta, theta, alpha, beta and gamma frequency bands. To examine the differences of EEG coherence according to sex in each group, ANCOVA was performed using Statistical Analysis system (SAS, Ver 9.3) and R (Ver 2.15.2). Results Healthy control males showed more increased right intrahemispheric coherences than healthy control females in delta, theta, alpha and beta frequency bands. In patients with schizophrenia, this male dominant pattern in right intrahemispheric coherences was attenuated especially in alpha and beta bands. Healthy control females showed more increased interhemispheric coherences than healthy control males in delta, theta, beta and gamma frequency bands. In patients with schizophrenia, these female dominant patterns in interhemispheric coherences were attenuated especially in delta, theta, and beta bands, which were commonly observed in frontal to central areas. Conclusion Sex differences in resting EEG coherences were attenuated in schizophrenia patients. These results imply that sex-related aberrant cerebral lateralization might exist in patients with schizophrenia, which are partly due to sex hormones via epigenetic mechanisms.

• Journal of Korea Water Resources Association
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• v.47 no.12
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• pp.1227-1237
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• 2014

Dual-polarization can distinguish precipitation type and dual-polarization is provide not only meteorological phenomena in the atmosphere but also non-precipitation echoes. Therefore dual-polarization radar can improve radar estimates of rainfall. However polarimetric measurements by transmitting vertically vibration waves and horizontally vibrating waves simultaneously is contain systematic bias of the radar itself. Thus the calibration bias is necessary to improve quantitative precipitation estimation. In this study, the calibration bias of reflectivity (Z) and differential reflectivity ($Z_{DR}$) from the Bislsan dual-polarization radar is calculated using the 2-Dimensional Video Disdrometer (2DVD) data. And an improvement in rainfall estimation is investigated by applying derived calibration bias. A total of 33 rainfall cases occurring in Daegu from 2011 to 2012 were selected. As a results, the calibration bias of Z is about -0.3 to 5.5 dB, and $Z_{DR}$ is about -0.1 dB to 0.6 dB. In most cases, the Bislsan radar generally observes Z and $Z_{DR}$ variables lower than the simulated variables. Before and after calibration bias, compared estimated rainfall from the dual-polarization radar with AWS rain gauge in Daegu found that the mean bias has fallen by 1.69 to 1.54 mm/hr, and the RMSE has decreased by 2.54 to 1.73 mm/hr. And estimated rainfall comparing to the surface rain gauge as ground truth, rainfall estimation is improved about 7-61%.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.344-344
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• 2014

Transparent amorphous oxide semiconductors such as a In-Ga-Zn-O (a-IGZO) have advantages for large area electronic devices; e.g., uniform deposition at a large area, optical transparency, a smooth surface, and large electron mobility >10 cm2/Vs, which is more than an order of magnitude larger than that of hydrogen amorphous silicon (a-Si;H).1) Thin film transistors (TFTs) that employ amorphous oxide semiconductors such as ZnO, In-Ga-Zn-O, or Hf-In-Zn-O (HIZO) are currently subject of intensive study owing to their high potential for application in flat panel displays. The device fabrication process involves a series of thin film deposition and photolithographic patterning steps. In order to minimize contamination, the substrates usually undergo a cleaning procedure using deionized water, before and after the growth of thin films by sputtering methods. The devices structure were fabricated top-contact gate TFTs using the a-IGZO films on the plastic substrates. The channel width and length were 80 and 20 um, respectively. The source and drain electrode regions were defined by photolithography and wet etching process. The electrodes consisting of Ti(15 nm)/Al(120 nm)/Ti(15nm) trilayers were deposited by direct current sputtering. The 30 nm thickness active IGZO layer deposited by rf magnetron sputtering at room temperature. The deposition condition is as follows: a rf power 200 W, a pressure of 5 mtorr, 10% of oxygen [O2/(O2+Ar)=0.1], and room temperature. A 9-nm-thick Al2O3 layer was formed as a first, third gate insulator by ALD deposition. A 290-nm-thick SS6908 organic dielectrics formed as second gate insulator by spin-coating. The schematic structure of the IGZO TFT is top gate contact geometry device structure for typical TFTs fabricated in this study. Drain current (IDS) versus drain-source voltage (VDS) output characteristics curve of a IGZO TFTs fabricated using the 3-layer gate insulator on a plastic substrate and log(IDS)-gate voltage (VG) characteristics for typical IGZO TFTs. The TFTs device has a channel width (W) of $80{\mu}m$ and a channel length (L) of $20{\mu}m$. The IDS-VDS curves showed well-defined transistor characteristics with saturation effects at VG>-10 V and VDS>-20 V for the inkjet printing IGZO device. The carrier charge mobility was determined to be 15.18 cm^2 V-1s-1 with FET threshold voltage of -3 V and on/off current ratio 10^9.

• Polymer(Korea)
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• v.30 no.1
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• pp.56-63
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• 2006

We have synthesized two types of diamine monomers containing various chain length to prepare polyimides with layered structure. By using these diamines, homo-polyimides and co-polyimides having hydrophobic and hydrophilic segment of flexible side chain were synthesized. The segregated layered structures were formed by repulsive force with main chain as the side chains reach a critical length because the rigid main chains are packed into layered structure with the flexible side chains occupying the space between layers. As a result, the gallery space of each homo-polyimide was increased at spacing of $32.7\~48{\AA}\;or\;7\~10.5{\AA}$ as the increased hydrophobic or hydrophilic side chain length through X-ray diffraction. The gallery space of co-polyimides was also showed similar phenomenon by repulsive force of side chains with different properties. We have also confirmed that gallery space and molar volume were significantly depended on length of flexible side chain via molecular modeling.

• 보존과학연구
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• s.37
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• pp.27-41
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• 2016

This study surveyed color awareness and color systems according to pedigree(Ilseob, Woljoo, Hyegak, Manbong ect.) targeting Dancheongjang (craftsman) who has inherited Dancheong (traditional multicolor). From the survey of color awareness, standardized color system of 'traditional color' awareness by Dancheongjang is 'the color inherited by the master' and it was identified that there is the standardized color system in awareness and its standard is either same or similar to traditional Dancheong. Also, according to each period, colors of Dancheong have been changed, it was thought that change in color materials and preference had went with times. From eleven main colors of Dancheong, chromaticity materials which were preferred by Dancheongjang were analyzed by the faction of Dancheongjang and colors and it resulted in a variety of color ranges over all. In the case of Yangnok, Noerok, Juhong it showed a high deviation with a wide color range while there was a low deviation with a narrow color range in Hayeop, Daja, Seokganju. Through this study it was difficult to identify clear correlations and tendencies of color system by the faction of Dancheongjangs. This is judged to be a reflection of the subjective artistry of the members.