• Journal of the Computational Structural Engineering Institute of Korea
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• v.20 no.2
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• pp.137-146
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• 2007

Numerical analyses are performed to show the effect of stiffening facade riggers on the behavior of the structure and to investigate the optimum locations of facade riggers. Optimum locations of the facade riggers to minimize the drift at the top of the structure are obtained by maximizing the drift reduction caused by the facade riggers and are significantly influenced by the bending and shear stiffnesses of the braced frame and facade riggers. Three standard load cases of uniformal and triangularly distributed lateral loads as well as a lateral point load at the top of the structure are considered in this paper Optimum locations of facade riggers are plotted as functions of nondimensional relative stiffness parameters ${\omega}$ and ${\beta}$ for structures with one to four riggers. Although the analysis presented herein is based on certain simplifying assumptions, it is believed that the results do provide sufficiently accurate information for determining the optimum locations of facade riggers in highrise structures.

• Journal of Digital Convergence
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• v.15 no.8
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• pp.225-234
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• 2017

This study was conducted with male/female teenagers to examine the interaction between their attachment to social media and their self-identity in both real space and cyberspace. Among the subjects, male teenagers tended to use social media more than female teenagers. Also, the more friends/followers they have, the more they would use the service itself. In the subordinate correlation of the subjects' self-identity in both cyberspace and real space, most areas showed positive correlation. And each subregion of the areas of real-space ego-identity and social media addiction showed positive correlation with them as well. On the other hand, in areas of social media addiction and cyberspace ego-identity, all areas showed negative correlation except the area of dominance. Through this experiment, it was proven apparent that there needs to be proper management of teenagers that are overusing and are addicted to social media, and that programs should be developed to mediate the subjects in regards to each subregion of real space and cyberspace ego-identity.

• Archives of Pharmacal Research
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• v.26 no.4
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• pp.294-300
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• 2003

A polysaccharide fraction, AIP1, purified from Artemisia iwayomogi was shown to have immunomodulating and anti-tumor activities in mice. In order to determine how the AIP1 fraction exhibits the immunomodulating activity, the effect of the fraction on the apoptosis of mouse spleen cells was investigated. Treatment of the mouse spleen cells with the AIP1 fraction resulted ,in the suppression of apoptotic death and an extension of cell survival in culture, indicating that the fraction might modulate the death of spleen cells. Treatment of the mice with the AIP1 fraction in vivo also resulted in less apoptosis of the spleen cells, which indicates the physiological relevance of the anti-apoptosis effect of the fraction in vitro. A mouse gene array was used to determine the profile of the gene expression change showing a pattern of up- and down-regulated genes by the AIP1 treatment. This study provides preliminary information regarding the immunomodulatory mechanism of the AIP1 fraction.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.3
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• pp.118-126
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• 2007

Tongue diagnosis is a profound and special part of the whole Oriental Medicine. We examined the method, the principle and the meaning of tongue diagnosis according to a literature cited, considered a meaning of tongue diagnosis. As a result, we come to a conclusion like that. 1. Tongue is related with internal organs by meridian system, especially has a direct connection with heart and spleen. 2. The heart, a master of internal organs, has its specific opening in the tongue. The spleen, source of nutrients for growth and development, has its specific body opening in the mouth. So tongue reflects states of internal organs, Qi, blood, the constructive energy and the defensive energy. 3. When doing tongue diagnosis, we must pay attention to the position and the order of inspection of the tongue. We must diagnose by referring to a ray of light, diet, season, age, physical constitution, habit and taste, can make a accurate diagnosis. 4. We can classify constitutions, distinguish syndromes, suppose prognosis, make a prescription by using tongue diagnosis. 5. Reddened tip of the tongue represents flaring-up of the heart fire, and it means psychologic stress. Dental identations on the tongue edges represents deficiency of Qi of the spleen, and it means physiologic fatigue. 6. Through observing humidity of fur of the tongue, we can guess psychologic stress and physiologic fatigue. Through observing thickness of fur of the tongue, we can guess function of spleen and stomach.

• Proceedings of the Optical Society of Korea Conference
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• 2007.07a
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• pp.243-244
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• 2007

본 연구에서는 성형용 코어 가공에서 초경합금(WC, Co 0.5%)의 초정밀 가공특성을 파악하기 위하여 다이아몬드 휠의 메시, 주축 회전속도, 터빈 회전속도, 이송속도 및 연삭깊이에 따른 표면거칠기를 측정하여 최적연삭조건을 규명하였다. 규명된 최적연삭가공조건을 활용하여 페러렐 연삭법으로 초정밀 연삭가공을 수행하였다. 연삭가공은 초정밀가공기(ASP01, Nachi-Fujikoshi Co., Japan)를 사용하였다. 최종 정삭가공을 수행한 비구면 성형용 코어의 형상측정결과 형상정도(PV; ${\varphi}$ 3.0mm) 0.15${\mu}m$(비구면), 0.10${\mu}m$(평면)으로 3M급 이상의 고화질 카메라폰에 채용되고 있는 비구면 Glass렌즈 양산용 성형용 코어 규격에 만족한 결과로서 본 연구에 수행된 초정밀 가공조건 및 측정방법이 매우 유효함을 알 수 있었다. 형상정도(PV) 및 표면조도(Ra) 측정은 초정밀 자유곡면 측정기(UA3P, Panasonic Co., Japan)와 3차원 표면조도 측정기(NewView5000, Zygo Co., USA)를 각각 사용하였다. 초정밀 가공된 성형용 코어면에 이온증착법을 활용하여 DLC 코팅을 수행하였다. 코팅 전후의 성형용코어를 활용하여 Glass소재(K-BK7, Sumita Co., Japan)를 최적의 성형조건(성형온도, 압력, 냉각속도)으로 성형하였다. DLC 코팅과 성형은 DLC 코팅기(NC400, Nanotech Co., Japan)와 Glass렌즈 성형기(Nano Press-S, Sumitomo Co., Japan)을 각각 사용하였다. Fig. 1은 초정밀 연삭가공, DLC 코팅막 구조, 코팅된 성형용 코어, 그리고, 성형된 비구면Glass렌즈를 각각 나타낸다.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.146-146
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• 2017

The pod shattering or dehiscence is essential for the propagation of pod-bearing plant species in the wild, but it causes significant yield losses during harvest of domesticated crop plants. Identifying novel molecular makers, which are linked to seed-shattering genes, is needed to employ the molecular marker-assisted selection for efficiently developing shattering-resistant soybean varieties. In this study, a genetic linkage map was constructed using 115 recombinant inbred lines (RILs) developed from crosses between the pod shattering susceptible variety, Keunol, and resistant variety, Sinpaldal. A 180 K Axiom(R) SoyaSNPs data and pod shattering data from two environments in 2001 and 2015 were used to identify quantitative trait loci (QTL) for pod shattering. A major QTL was identified between two flanking single nucleotide polymorphism (SNP) markers, AX-90320801 and AX-90306327 on chromosome 16 with 1.3 cM interval, 857 kb of physical range. In sequence, genotype distribution analysis was conducted using extreme phenotype RILs. This could narrow down the QTL down to 153 kb on the physical map and was designated as qPDH1-KS with 6 annotated gene models. All exons within qPDH1-KS were sequenced and the 6 polymorphic SNPs affecting the amino acid sequence were identified. To develop universally available molecular markers, 38 Korean soybean cultivars were investigated by the association study using the 6 identified SNPs. Only two SNPswere strongly associated with the pod shattering. These two identified SNPs will help to identify the pod shattering responsible gene and to develop pod shattering-resistant soybean plants using marker-assisted selection.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.145-145
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• 2017

Foxglove aphid, Aulacorthum solani (Kaltenbach), is a Hemipteran insect that infected a wide variety of plants worldwide and caused serious yield losses in crops. The objective of this study was to identify the putative genes to foxglove aphid resistance in wild soybean, PI 366121 (Glycine soja Sieb. and Zucc.). One hundred and forty-one F4:8 recombinant inbred lines developed from a cross between susceptible variety, Williams 82 and foxglove aphid resistance wild soybean, PI 366121 were used. The two type of resistance response, antibiosis and antixenosis resistance were evaluated through choice and no-choice test, graded by the degree of total plant damage and primary infestation leaf damage; a genome-wide molecular linkage map was constructed with 29,898 single-nucleotide polymorphism markers utilizing a Axiom(R) 180K soyaSNP array. Using inclusive composite interval mapping analysis for foxglove aphid resistance, one major candidate QTL on chromosome 7 was identified. The major QTL on chromosome 7 showed both antixenosis and antibiosis resistance responses. The newly identified major QTL was consistent with previously reported QTL, Raso2, which showed around 5 times narrow down interval range with 8 candidate genes. Furthermore, total 1,115 soybean varieties including Glycine soja and Glycine max were exposed to germplasm screening, and 31 varieties, which showed significant antibiosis type foxglove aphid resistance were identified. This result could be useful in breeding for new foxglove aphid resistant soybean cultivars and developing novel insecticides.

• The Journal of Korean Physical Therapy
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• v.25 no.4
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• pp.204-209
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• 2013

Purpose: Children with cerebral palsy generally have a high incidence of respiratory problem, resulted from poor coughing, airway clearance problem, respiratory muscle weakness, kyphoscoliosis and so forth. The purpose of this study is to investigate the possible factors that can be affected to forced vital capacity (FVC) in children with cerebral palsy. Methods: Total thirty six children with diplegic and hemiplegic cerebral palsy were recruited in this study. They were evaluated by general demographic data (i.e., age, gender, body mass index (BMI)) and variables related to respiratory functions (i.e., chest mobility, waist mobility, maximal phonation time, and maximum inspiratory/expiratory pressure (MIP/MEP)). The correlation between forced vital capacity and the rested variables were analyzed, and multiple regression with stepwise method was conducted to predict respiratory function, in terms of FVC as the dependent variable, and demographic and other respiratory variables as the independent variable. Results: FVC showed a significant correlation with waist mobility (r=0.59, p<0.01), maximal phonation time (r=0.48, p<0.05), MIP (r=0.73, p<0.01), and MEP (r=0.60, p<0.01). In addition, the multiple regression analysis model indicated that FVC could be predicted by the assessment of each waist mobility and MIP. Conclusion: These finding suggest that respiratory function is related to body size and respiratory muscle strength, and that BMI, waist mobility, and MIP can be predictable factors to affected respiratory function in term of FVC.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.4 no.1
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• pp.43-70
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• 1994

The effects of potassium chromate (500ppm/500ppm), potassium dichromate (500ppm/500ppm), cobalt chloride (100ppm/10ppm), methylmercuric chloride (100ppm/10ppm) on the biosynthesis of phospholipid and their composition of fatty acids in E.coli and B.subtilis were analyzed. The contents of phosphatidylethanolamine, phosphatidylcholine, phosphatidylinositol, phosphatidylglycerol, cardiolipin and total lipids in treatment with metal compounds were lower to compare with the control. The major fatty acid utilized for biosynthesis of phospholipid was palmitic acid in control of E.coli and B.subtilis. However, in treatment with metal compounds, changes of fatty acid composition utilized for phospholipid formation were as follows. In E.coli major fatty acids were palimitic acid (ave. 26.26%) and cis-vaccenic acid (ave. 10.94%) in treatment with potassium chromate, palmitic acid (ave. 31.41%/31.42%) and stearic acid (ave. 17.92%/19.41%) in treatment with potassium dichromate and cobalt chloride. And in treatment with raethylmercuric chloride, palmitic acid (ave. 26.66%), stearic acid (ave. 15.50%) and cis-vaccenic acid (ave. 20.59%) were used in phospholipid formation. In B.subtilis, the major fatty acid was palmitoleic acid (ave. 15.29% /10.22%) in treatment with potassium chromate and cobalt chloride, and stearic acid (ave. 16.01%) in treatment with potassium dichromate. On the other hand, cis-vaccenic acid (ave. 9.09%), palmitic acid (ave. 17.23%), stearic acid (ave. 6.66%), myristic acid (ave. 6.34%) and lauric acid (ave. 4.75%) were analyzed into major fatty acids in treatment with methylmercuric chloride. As shown in results, specific fatty acid pattern was came out in treatment with metal compounds according to bacteria and treatments.

• Biomolecules & Therapeutics
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• v.21 no.6
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• pp.442-446
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• 2013

Here in this study, we isolated 1,2,3,4,6-penta-O-galloyl-${\beta}$-D-glucose (PGG) from Curcuma longa L. and elucidated the lifespan-extending effect of PGG using Caenorhabditis elegans model system. In the present study, PGG demonstrated potent lifespan extension of worms under normal culture condition. Then, we determined the protective effects of PGG on the stress conditions such as thermal and oxidative stress. In the case of heat stress, PGG-treated worms exhibited enhanced survival rate, compared to control worms. In addition, PGG-fed worms lived longer than control worms under oxidative stress induced by paraquat. To verify the possible mechanism of PGG-mediated increased lifespan and stress resistance of worms, we investigated whether PGG might alter superoxide dismutase (SOD) activities and intracellular ROS levels. Our results showed that PGG was able to elevate SOD activities of worms and reduce intracellular ROS accumulation in a dose-dependent manner.