• Journal of Korean Ophthalmic Optics Society
• /
• v.12 no.4
• /
• pp.43-54
• /
• 2007

Silicone hydrogel contact lenses developed as a continuous-wear modality are now used as a daily-wear contact lenses. The purpose of this study was to investigate the clinical performance in a group of successful long-term wearers of conventional hydrogel contact lenses when refitted with daily wear $O_2OPTIX$ silicone hydrogel lenses. Sixty-two wearers ($30.7{\pm}19.9$ months of prior lens wear) among sixty-five soft lens wearers refitted with $O_2OPTIX$ silicone hydrogel lenses were participated in this study finally. Subjective symptoms were scored and objective signs were graded using CCLRU scales during the study period. 98% of subjects were successfully refitted with the one base curve of $O_2OPTIX$, and 33.9% of subjects were needed more or less lens powers compared with their habitual lenses. Subjects reported a concurrent reduction in dryness, redness and tiredness compared with their habitual lenses and both subjective and objective evaluations showed that dryness, tiredness, itchiness, bulbar and limbal hyperemia were decreased and significantly decreased particularly for those subjects with greater baseline symptoms (p<0.0001). But corneal staining was increased and was seen in many subjects during the study (p<0.0001). Refitting existing soft contact lens wearers with silicone hydrogel contact lens could result in a decreased in dryness, redness and tiredness, particularly more effective for those subjects with greater baseline of those symptoms. When patients using conventional hydrogel materials switch to a silicone hydrogel material, the potential for increased corneal staining should be considered and over-refraction should be needed to give a best vision.

• Journal of Integrative Natural Science
• /
• v.13 no.1
• /
• pp.13-18
• /
• 2020

This study used cerium iron hydroxide nanoparticle with HEMA (2-hydroxyethyl methacrylate), the cross-linker EGDMA (ethylene glycol dimethacrylate), NVP (N-vinyl-2-pyrrolidone) and the initiator AIBN (azobisisobutyronitrile) for copolymerization. Also, the physical properties of the prepared lenses were compared, and their applicability as polymers for ophthalmic materials was experimented. The results of the measurement showed that the UV blocking rate and the wettability increased with the cerium iron hydroxide nanoparticles addition ratio, and the refractive index and water content were not affected. Thus, the produced copolymer is expected to be useful as a functional contact lens material while satisfying the basic physical properties of the hydrogel contact lens.

• Journal of Korean Ophthalmic Optics Society
• /
• v.18 no.3
• /
• pp.271-277
• /
• 2013

Purpose: The purpose was to study the corneal refractive power changes associated with the wearing of everted silicone hydrogel soft lenses. Methods: The corneal refractive power and corneal astigmatism were measured using corneal topographer (CT-1000, Shin-nippon Co., Japan) for checking change of corneal refractive power and objective refractive error was measured by auto-refractometer (Natural vision-K 5001, Shin-nippon Co., Japan). We measured at baseline and 1 week after lens wearing. Results: The correcting of corneal refractive power could be effective in low myopia. It's more effective to the higher power of greatest meridian of cornea and the more corneal astigmatism. 73% of subjects' refractive error was decrease less than 1 D and 17% of the subjects had an reverse effect (increase) occurs. The reduction of objective refractive error was more effective when cornea refractive power was great or corneal astigmatism was much. Conclusions: Pressure which the everted silicone hydrogel lens to the cornea could be caused. It occurred as the degrees of corneal power, corneal astigmatism and objective refractive error differences. Selection of an appropriate subject is important considering difficulty of changing the parameters of the lens.

• Journal of Korean Ophthalmic Optics Society
• /
• v.19 no.1
• /
• pp.43-49
• /
• 2014

Purpose: The physical and optical characteristics of hydrophilic contact lens polymerized with addition of glycerin and PVP(polyvinylpyrrolidone) in the basic hydrogel contact lens material were evaluated. Methods: This study used glycerin and PVP(polyvinylpyrrolidone) with the cross-linker EGDMA (ethylene glycol dimethacrylate), HEMA (2-hydroxyethyl methacrylate) and the initiator AIBN (azobisisobutyronitrile) for copolymerization. Results: Measurements of the physical characteristics of the copolymerized material including PVP(polyvinylpyrrolidone) showed the refractive index of 1.4382~1.4288, tensile strength of 0.3446~2542 kgf and water content and contact angle of sample showed the increase of 13.49% and decrease of 21.44% independently. And also, the physical characteristics of the copolymerized material including glycerin showed the refractive index of 1.4330~1.4328, tensile strength of 0.2974~0.2854 kgf, water content 35.58~36.53% and contact angle of sample showed the decrease of 37.64%. Conclusions: Based on the results of this study, the produced copolymers is suitable for conventional lens with high wettability. Also, glycerin minimized the changes of water content and refractive index at the same time, increased the wettability of the hydrogel lens materials.

• Journal of Korean Ophthalmic Optics Society
• /
• v.20 no.2
• /
• pp.105-115
• /
• 2015

Purpose: The accuracy for measuring the refractive power of hydrogel contact lenses by spectacle lens holder and contact lens holder was evaluated. The accuracy for each sample was also analyzed with water content and diopter categories. Methods: The hydrogel contact lenses used for measurement were classified into three categories in water content (38%, 43%, 58%). Also, three diopter categories of refractive power were used such as -3.000 D, -7.000 D, -10.000 D. And also, the reliability of measurement results were evaluated by measuring refractive power with spectacle lens holder and contact lens holder using an Manual lensmeter. Results: In case of spectacle lens holder method, the average value of refractive power was -3.3273D for -3.0000 D, -7.1306 D for -7.0000 D and -10.2944 D for -10.0000 D, respectively. In case of contact lens holder method, the average value of refractive power was -3.1060 D for -3.0000 D, -7.0028 D for -7.0000 D and -10.2611 D for -10.0000 D, respectively. In measurement of all diopters, the accuracy of contact lens holder method was better than spectacle lens holder method. Conclusions: From these results, it is judged that the refractive power of soft contact lens by manual lensmeter with contact lens holder have a higher accuracy than spectacle lens holder.

• Journal of Korean Ophthalmic Optics Society
• /
• v.20 no.4
• /
• pp.437-443
• /
• 2015

Purpose: This study evaluated the optical and physical and characteristics of soft contact lens polymerized with addition of 3-chloropyridine-4-carboxylic acid and 3-fluoropyridine-4-carboxylic acid in the basic hydrogel contact lens material. In particular, the utility of 3-chloropyridine-4-carboxylic acid and 3-fluoropyridine- 4-carboxylic acid as a hydrogel contact lens material was investigated. Methods: In this study, 3-chloropyridine-4-carboxylic acid and 3-fluoropyridine-4-carboxylic acid were used as additives. Also, 2-hydroxyethyl methacrylate, acrylic acid, methyl methacrylate and a cross-linker EGDMA were co-polymerized in the presence of AIBN as an initiator. Results: The physical properties of the produced polymers were measured as followings. The water content of 34.54~37.15%, refractive index of 1.4320~1.4342, tensile strength of 0.2872~0.3608 kgf and contact angle of $57.82{\sim}79.57^{\circ}$, UV-B transmittance of 76.8~82.4% and UV-A transmittance of 84.6~86.6% were obtained respectively. Conclusions: Based on the results of this study, contact lens material containing 3-chloropyridine-4-carboxylic acid and 3-fluoropyridine-4-carboxylic acid is expected to be able to used as a material for high wettability and UV-block hydrogel contact lens.

• Journal of Korean Ophthalmic Optics Society
• /
• v.5 no.1
• /
• pp.73-81
• /
• 2000

This review on ocular toxicology concentrates on the effects on ocular health and contact lens wear induced by systemically used drugs, including alcohol. Many systemically administered drugs produce ocular adverse effects. Fortunately, relatively few are capable of causing significant, irreversible visual impairment. The visual symptoms of acute intoxication are as follows : Drop in vision/visual acuity, diplopia, poor dark adaptation, increase in time for glare recovery, early cataract, decreased depth perception, blue-yellow or red-green colour defect and visual hallucinations. Blinking pattern, tear production, and discoloration of contact lenses can be affected by some systemic or local ocular medications. The cornea, conjunctiva, or eyelids may react to some systemic medications and to some preservatives used in contact lens solutions. The hydrogel contact lens act as a drug reservoir that emits the drug over time. I discuss management of contact lens-induced infectious and inflammatory conditions.

• Journal of Integrative Natural Science
• /
• v.7 no.1
• /
• pp.5-10
• /
• 2014

A study that copolymerized Ag nanoparticle and furfuryl isocyanate with the crosslinking agent EGDMA (ethylene glycol dimethacrylate), HEMA (2-hydroxyethyl methacrylate), MMA (methyl methacrylate), MA (methacrylic acid) and the initiating agent AIBN (azobisisobutyronitrile) is presented. Measurement of the physical characteristics of the produced macromolecule showed that the water content is 32.08~32.67%, refractive index 1.446~1.448, visible light transparency 83.2~67.6%, contact angle $68.2{\sim}83.5^{\circ}$ and tensile strength 0.541~0.755 kgf. It is also demonstrated that the addition of Ag nanoparticles is associated with the reduction of UV-B transmittance and increase in tensile strength. The results show that the produced copolymer can be used as a material for ophthalmic lenses with durability and UV-blocking properties.

• Journal of Korean Ophthalmic Optics Society
• /
• v.18 no.4
• /
• pp.457-463
• /
• 2013

To determine the impact of artificial tears which include carboxymethyl cellulose on a hydrogel contact lenses. Methods: A contact lenses made of the cross-linking agent, EGDMA (ethylene glycol dimethacrylate) and HEMA (2-hydroxyethyl methacrylate) and with added NVP (n-vinyl-2-pyrrolidone) and MMA (methyl methacrylate) was evaluated for water content, refractive index, spectral transmittance and contact angle of produced contact lens. Results: The physical properties of the sampled copolymerized polymers showed that water content, refractive index, visible ray transmittance and contact angle were in the range of 26.61%~48.58%, 1.422~1.455, 80.8%~91.4% and $33.93^{\circ}{\sim}65.70^{\circ}$, respectively. In addition, after soaking with artificial tears, the water content, refractive index and contact angle were in the range of 24.46%~48.25%, 1.422~1.457, 77.0%~91.0% and $37.25^{\circ}{\sim}77.33^{\circ}$, respectively. The changes of the physical property depending on hydration time and showed an increase of refractive index and contact angle, decrease of water content and visible ray transmittance. Conclusions: Artificial tears which include carboxymethyl cellulose sodium which is used as a wetting agent influenced water content, refractive index, contact angle and spectral transmittance of a hydrogel contact lenses.

• Journal of Korean Ophthalmic Optics Society
• /
• v.13 no.4
• /
• pp.59-63
• /
• 2008

Purpose: The purpose of this study is to understand a relation of water content measurement with two different method, water removal method and dry method. Methods: 72 hydrogel contact lens containing various water content (ranged from 47% to 58%) were measured by the gravimetric method at 20$^{\circ}C$and 21% of the humidity. We weighed the dried test specimen at room temperature for 30 min after cooling. Results: In dry blotting method, the water content was measured to 47.43${\pm}$8.48%. The water contents was measured to 48.15${\pm}$8.36% with wet blotting condition. It was found that wet blotting method showed the higher water content of about 7% than dry blotting method. In water content with two dry methods, each of results was measured by 47.89${\pm}$8.06% and 49.56${\pm}$7.06%. In case of microwave method, the water content was measured significantly higher water content of about 1.67% than vacuum oven method. However, no statistical difference was found (p>0.05). Conclusions: In water removal method (Dry blotting method and Wet blotting method) to weigh hydrated test specimen, wet blotting method showed significantly higher water content than dry blotting method. Also in case of dry methods (vacuum oven and microwave) to weigh dry test specimen, water content of microwave method showed higher water content than vacuum oven method, but it should be noted that microwave oven method must be used carefully to measure accurateness on the specimen position and wave power.