• Title/Summary/Keyword: Hybrid Strategy

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Cre-Lox: A Tool for Removal of Marker Genes to Make GM Foods Safe

  • Zargar, Sajad M.;Mushtaq, Roohi;Joshi, Manisha;Prasad, D. Theertha;Bhat, Nazir Ahmad;Agrawal, Ganesh Kumar;Rakwal, Randeep
    • Journal of Crop Science and Biotechnology
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    • v.10 no.2
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    • pp.73-78
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    • 2007
  • The green revolution has significantly helped in increasing the food production. So far, various breeding methods have been exploited, besides them recombination DNA technology provides another approach for increasing the food production. By means of this technology the losses in food production incurred by various biotic and abiotic stresses can be effectively controlled. In most of the transgenic studies scientists have used antibiotic resistant genes as markers for easy selection of transformants but there are risks involved in use of GM foods. To make such foods safer and environment friendly we have discussed a novel strategy i.e. Cre-lox which involves site specific recombination. By means of Cre-lox the marker genes can be specifically removed once the selection of transformants is over. In addition, this strategy can be used to module the hybrid chromosomes, avoid gene silencing and incorporate single copy of a transgene for its higher expression.

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An efficient and novel strategy for control of cracking, creep and shrinkage effects in steel-concrete composite beams

  • Varshney, L.K.;Patel, K.A.;Chaudhary, Sandeep;Nagpal, A.K.
    • Structural Engineering and Mechanics
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    • v.70 no.6
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    • pp.751-763
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    • 2019
  • Steel-concrete composition is widely used in the construction due to efficient utilization of materials. The service load behavior of composite structures is significantly affected by cracking, creep and shrinkage effects in concrete. In order to control these effects in concrete slab, an efficient and novel strategy has been proposed by use of fiber reinforced concrete near interior supports of a continuous beam. Numerical study is carried out for the control of cracking, creep and shrinkage effects in composite beams subjected to service load. A five span continuous composite beam has been analyzed for different lengths of fiber reinforced concrete near the interior supports. For this purpose, the hybrid analytical-numerical procedure, developed by the authors, for service load analysis of composite structures has been further improved and generalized to make it applicable for composite beams having spans with different material properties along the length. It is shown that by providing fiber reinforced concrete even in small length near the supports; there can be a significant reduction in cracking as well as in deflections. It is also observed that the benefits achieved by providing fiber reinforced concrete over entire span are not significantly more as compared to the use of fiber reinforced concrete in certain length of beam near the interior supports in continuous composite beams.

New Helicobacter pylori Eradication Therapies (새로운 헬리코박터 제균 요법)

  • Park, Jae Yong;Kim, Jae Gyu
    • The Korean Journal of Gastroenterology
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    • v.72 no.5
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    • pp.237-244
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    • 2018
  • While the prevalence of Helicobacter pylori (H. pylori) infection is decreasing in Korea, the incidence of gastric cancer remains high, emphasizing the importance of H. pylori eradication. A new treatment strategy is needed as the eradication rate with standard triple therapy, which is currently the standard first-line regimen for H. pylori infection, has decreased below the optimum level. The major cause of eradication failure is increased antibiotic resistance. Sequential, concurrent, and hybrid therapies that include clarithromycin produce higher eradication rates than conventional standard triple therapy. However, the effectiveness of these treatments is limited in regions where the resistance rate to various antibiotics is high. Bismuth quadruple therapy is another alternative therapy, but again the eradication rate is not sufficiently high. Tailored therapy based on individual characteristics, including antibiotic susceptibility, may be ideal, but there are several limitations for clinical application and further research is needed. New potassium-competitive acid blocker-based therapies could emerge as effective alternatives in the near future. A consensus is needed to establish a strategy for applying new eradication therapies in Korea.

Over-The-Top (OTT) Platforms' Strategies for Two-Sided Markets in Korea

  • Song, Minzheong
    • International Journal of Internet, Broadcasting and Communication
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    • v.13 no.4
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    • pp.55-65
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    • 2021
  • The purpose of this paper is to present the Over-The-Top (OTT) platforms' strategies for two-sided markets. For this, we examine six strategic factors influencing OTT's success in Korea. The analysis reveals, among six OTTs, Netflix utilizes five strategic factors except the same-side network effects. OTTs from pay TV operators and channel providers tend to block the cross-side network effects on the opponent OTTs, because they think their giveaway to content providers is in vein, if the invested content by them would be consumed on opponent rival platforms. Interesting is that after experiencing a negative association between the market entry of Netflix and the subscription revenue growth rate of pay TV services, pay TV operators utilize the same-side network effects by offering hybrid services in partnership with global OTTs like Netflix, Disney+ which are considered as a complementary OTT. In conclusion, it is suggested to target a new connected TV based OTT service offering with collaboration with Korean TV device manufacturers for Korean OTTs' global strategy, because Netflix-like global market expansion is not easy for them to cover their content cost.

Design Strategy for Residential Complex based on Landscape Urbanism

  • Choi, Jae-Hyun
    • International Journal of Advanced Culture Technology
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    • v.9 no.1
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    • pp.121-128
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    • 2021
  • In this study, we aim to suggest direction for landscape design of residential complex in Korea by studying target areas to understand how landscape urbanism was applied to residential landscape design as it is the majority of landscape design in Korea and by closely examining design elements to be considered for design of residential complex based on landscape urbanism theory. For the purpose of the study, some of public multifamily housing complex were selected as target areas and a survey was first conducted to understand how landscape urbanism was applied to design of these target areas. Then, by analyzing the survey results, we identified which elements were of importance to designing of multifamily housing complexes in Korea and how practical design of landscape urbanism works. From this study, we concluded that landscape urbanism theory is not just about design strategies, but more of comprehensive design methodology covering both operation and management and that such theory can be appropriately applied to design of multi-housing complexes in Korea. We also discovered that in order to apply landscape urbanism in design stage for multi-housing complex, selecting which design strategy/words in the previous study is not what's important, but comprehensive understanding and interpretation of design languages is key.

Combining Hough Transform and Fuzzy Unsupervised Learning Strategy in Automatic Segmentation of Large Bowel Obstruction Area from Erect Abdominal Radiographs

  • Kwang Baek Kim;Doo Heon Song;Hyun Jun Park
    • Journal of information and communication convergence engineering
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    • v.21 no.4
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    • pp.322-328
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    • 2023
  • The number of senior citizens with large bowel obstruction is steadily growing in Korea. Plain radiography was used to examine the severity and treatment of this phenomenon. To avoid examiner subjectivity in radiography readings, we propose an automatic segmentation method to identify fluid-filled areas indicative of large bowel obstruction. Our proposed method applies the Hough transform to locate suspicious areas successfully and applies the possibilistic fuzzy c-means unsupervised learning algorithm to form the target area in a noisy environment. In an experiment with 104 real-world large-bowel obstruction radiographs, the proposed method successfully identified all suspicious areas in 73 of 104 input images and partially identified the target area in another 21 images. Additionally, the proposed method shows a true-positive rate of over 91% and false-positive rate of less than 3% for pixel-level area formation. These performance evaluation statistics are significantly better than those of the possibilistic c-means and fuzzy c-means-based strategies; thus, this hybrid strategy of automatic segmentation of large bowel suspicious areas is successful and might be feasible for real-world use.

Hybrid Off-pump Coronary Artery Bypass Combined with Percutaneous Coronary Intervention: Indications and Early Results (심폐바이패스 없이 시행하는 관상동맥우회술과 경피적 관상동맥중재술의 병합요법 : 적응증 및 조기성적)

  • Hwang Ho Young;Kim Jin Hyun;Cho Kwang Ree;Kim Ki-Bong
    • Journal of Chest Surgery
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    • v.38 no.11 s.256
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    • pp.733-738
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    • 2005
  • Background: The possibility of incomplete revascularization and development of flow competition after revascularization of the borderline lesion made the hybrid strategy as an option for complete revascularization. Material and Method: From January f998 to July 2004, 25 $(3.2\%)$ patients underwent hybrid revascularization among 782 total OPCAB procedures. Clinical results and angiographic patencies were evalulated. Percutaneous coronary intervention (PCI) was peformed before CABG in 8 patients and after CABG in 47 patients. Result: The causes of PCIs before CABG were to achieve complete revascularization with minimally invasive surgery (n=7) and emergent PCI for culprit lesion (n=1). The indications of PCIs after CABG were high possibility of flow competition in the borderline lesion of right coronary artery territory (n=8), diffuse atheromatous lesion preventing anastomosis of graft (n=5), severe calcified ascending aorta with no more arterial grafi available (n=3), and intramyocardial coronary lesion (n=1). Mean number of distal anastomoses was $2.3\pm1.0$. Mean number of lesions treated by PCI was $1.2\pm0.4$. There was no operative or procedure-related mortality. PCI-related complication was periprocedural myocardial infarction in one patient, and complications related to CABG were transient atrial fibrillation (n=5), perioperative myocardial infarction (n=1), and transient renal dysfunction (n=1). Early postoperative coronary angiography $(1.8{pm}1.6days)$ revealed $100\%$ patency rate of grafts (57/57). The stenosis occurred in one patient performed PCI before CABG, which was successfully treated with re-ballooning. During midterm follow-up (mean; $25{\pm}26$ months), 1 patient died of congestive heart failure. All survivors (n=24) accomplished follow-up coronary angiographics, which showed .all grafts (56/57) were patent except one string sign. In-stent restenosis was developed in 2 patients who received bare metal stents. Conclusion: In selected patients, complete revascularization was achieved with low risk by taking the hybrid strategy.

Chemically Modified Graphene and Their Hybrid Materials: Toward Printed Electronics

  • Jeong, Seung-Yeol
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.08a
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    • pp.71-71
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    • 2012
  • Chemically modified graphene has been great interest for the application of printed electronics using solution prossesable technique. Here, we demonstrate a large area graphene exfoliation method with fewer defects on the basal plane by application of shear stress in solution to obtain high quality reduced graphene oxide (RGO). Moreover, we introduce a novel route to preparing highly concentrated and conductive RGO in various solvents by monovalent cation-${\pi}$ interaction. Noncovalent binding forces can be induced between a monopole (cation) and a quadrupole (aromatic ${\pi}$ system). The stability of this RGO dispersion was more sensitive to the strength of the cation-${\pi}$ interactions than to the cation-oxygen functional group interactions. The RGO film prepared without a post-annealing process displayed superior electrical conductivity of 97,500 S/m. Our strategy can facilitate the development of large scalable production methods for preparing printed electronics made from high-quality RGO nanosheets.

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Comparison Thai Word Sense Disambiguation Method

  • Modhiran, Teerapong;Kruatrachue, Boontee;Supnithi, Thepchai
    • 제어로봇시스템학회:학술대회논문집
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    • 2004.08a
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    • pp.1307-1312
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    • 2004
  • Word sense disambiguation is one of the most important problems in natural language processing research topics such as information retrieval and machine translation. Many approaches can be employed to resolve word ambiguity with a reasonable degree of accuracy. These strategies are: knowledge-based, corpus-based, and hybrid-based. This paper pays attention to the corpus-based strategy. The purpose of this paper is to compare three famous machine learning techniques, Snow, SVM and Naive Bayes in Word-Sense Disambiguation on Thai language. 10 ambiguous words are selected to test with word and POS features. The results show that SVM algorithm gives the best results in solving of Thai WSD and the accuracy rate is approximately 83-96%.

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Development of a 100kW charging infra for electrical bus (전기버스용 100kW급 충전인프라 개발)

  • Lee, Chung-Woo;Oh, Seung-Hun;Lee, Yun-Jae;Choi, Eun-Sik;Kang, Byung-Kwan;Ryu, Kang-Yeul;Kim, Hee-Jung
    • Proceedings of the KIPE Conference
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    • 2013.11a
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    • pp.117-118
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    • 2013
  • Recent global warming to the promotion of electric vehicles (EV), plug-in hybrid (PEV), including the next generation of cars and solar power, wind power and other renewable energy, and next-generation power grid (smart grid) are getting attention. In addition, the system utilizes the battery life in the industry and the convenience of a variety of social systems, economics, environmental impact, and the inherent potential to change significantly, and you can not walk into a next-generation industrial strategy and the need increases more and more present, and its early commercialization In order to do this, as well as a key energy source, the battery charger for charging efficiency technologies is essential. In this paper, fast charge multiple battery modules and optional modules that can charge distribution charge will be introduced.

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