• 제목/요약/키워드: Hybrid Action

Search Result 141, Processing Time 0.039 seconds

Estimation of Genetic Components of Variance in Biparental Progenies of Bivoltine Silkworm (Bombyx mori L.)

  • Malik, Gulam Nabi;Sofi, Abdul Majeed;Haque Rufaie, Syed Zia;Singh, Tejender Paul;Aijaz, Mohammad;Malik, Manzoor Ahmad;Dar, Habib Ullah
    • International Journal of Industrial Entomology and Biomaterials
    • /
    • v.9 no.2
    • /
    • pp.279-281
    • /
    • 2004
  • Components of genetic variation were estimated for five metric traits using 24 biparental progenies (N. C. Design III) generated from F$_2$ generation of a commercial bivoltine silkworm hybrid, SH$_{6}$${\times}$NB$_4$D$_2$. Variance due to additive ($\sigma$$^2$A) and dominance ($\sigma$$^2$D) gene effects was significant for single cocoon weight and shell weight. However, magnitude of former was greater than latter indicating preponderance of additive gene action in the inheritance of these two traits. Average degree of dominance was in the range of partial dominance for all the traits. High estimates of heritability (ns) indicated operation of genes with large additive effects, hence, scope exists for improvement of present populations through a few cycles of selection.n.

A Usability Testing of a Hybrid Mobile Reading Game for Children With Reading Disabilities (읽기장애아동을 위한 하이브리드 모바일 읽기 게임의 사용성 검사)

  • Shin, Mikyung;Park, Eunhye;Hong, Ki-Hyung;Lee, Joohyun;Park, Hyewon
    • The Journal of the Korea Contents Association
    • /
    • v.18 no.1
    • /
    • pp.314-326
    • /
    • 2018
  • The purpose of this study was to evaluate the usability of a hybrid mobile reading game among 14 parents of children with reading disabilities. The reading game consisted of six steps according to the process of reading (familiarizing with consonants and vowels, acquiring whole words, combining consonants and vowels, reading words, phonological rules, reading fluency). In this study, parents experienced steps one through three of the reading-game app and evaluated the general design features and Universal Design for Learning on a five-point scale. Regarding the general design features, parents rated usability (18 items in total) as high in the following order: interactive design, instructional design, and interface design. Regarding the Universal Design for Learning (9 items in total), parents evaluated usability as high in the following order: providing multiple means of representation, providing multiple means of action and expression, and providing multiple means of engagement. Lastly, suggestions for the improvement of the app, practical implications, and suggestions for future research are discussed.

Flexural and Tensile Performance of Strain-Hardening Cement Composite with Synthetic Fibers (합성섬유를 사용한 변형경화형 시멘트 복합체의 휨 및 인장성능)

  • Kim, Sun-Woo;Lee, Min-Jung;Jang, Yong-Heon;Jang, Gwang-Soo;Song, Seon-Hwa;Yun, Hyun-Do
    • Proceedings of the Korea Concrete Institute Conference
    • /
    • 2008.04a
    • /
    • pp.925-928
    • /
    • 2008
  • Fiber is an important ingredient in strain-hardening cementitious composite (SHCC), which can control fracture of cementitious composite by bridging action. The properties of reinforcing fiber, as tensile strength, aspect ratio and elastic modulus, have great effect on the fracture behavior of SHCC. To apply SHCC to structural member, SHCC must have economical efficiency and workability as well as own excellent tensile performance. For these purposes, four-point bending and direct tensile tests on SHCC with only hybrid synthetic fibers, total fiber volume fraction, $V_f$, is 1.5%, are carried out. The research emphasis is on the mechanical properties of SHCC made in Polyvinyl alcohol (PVA) and Polyethylene (PE) fibers, and how this affects the composite property, and ultimately its strain-hardening performance. Also, effect of hybrid type and water-cement ratio on the behavior of SHCC was evaluated in this paper.

  • PDF

CHANGES IN INTRAPULPAL NERVE ACTIVITY AND OCCLUDING ASPECTS OF DENTINAL TUBULES BY DENTIN DESENSITIZER CONTAINING GLUTARALDEHYDE (Glutaraldehyde계 상아질 과민증 탈감작제에 의한 치수신경 활동성 변화 및 상아세관 폐쇄양상)

  • Kim, Jong-Hwa;Lee, Kwang-Won;Son, Ho-Hyun
    • Restorative Dentistry and Endodontics
    • /
    • v.21 no.2
    • /
    • pp.505-516
    • /
    • 1996
  • The effects of application of dentin desensitizer containing glutaraldehyde (Gluma Desensitizer) and dentin adhesive system (All Bond 2) to the exposed dentin on the intradental nerve activity (INA) and the occluding aspects of dentinal tubules were investigated in cat canine teeth. Single pulp nerve units were dissected from the inferior alveolar nerve and indentified as $A{\delta}$-fiber units. The INAs elicited by 4M NaCl before and after the application of each experimental agent were compared. The morphological changes of exposed dentin surfaces and dentinal tubules in the dentin specimens used to record INAs were observed by SEM. The results obtained were as follows. 1. Eight $A{\delta}$-fiber units (conduction velocity: $8.0{\pm}4.0m$/sec) were identified. 4M NaCl evoked an irregular burst of action potentials which ceased immediately after washing. 2. In 4 $A{\delta}$-fiber units, the change of INA after the application of Gluma Desensitizer was $133.9{\pm}80.7%$ when it was compared with the INA before the application of the same agent. 3. In 4 $A{\delta}$-fiber units, application of All Bond 2 completely abolished the INA induced by 4M NaCl. 4. In specimens applied with Gluma Desensitizer, the formation of hybrid layer as well as the identification of resin penetration and reaction products with proteins in dentinal tubules were not clearly observed in interface between dentin and adhesive resin. In specimens applied with All Bond 2, the gap width of 2-$3{\mu}m$ was formed between exposed dentin and adhesive resin, and the hybrid layer and resin tags were not clearly formed either.

  • PDF

Web-shear strength of steel-concrete composite beams with prestressed wide flange and hollowed steel webs: Experimental and practical approach

  • Han, Sun-Jin;Kim, Jae Hyun;Choi, Seung-Ho;Heo, Inwook;Kim, Kang Su
    • Structural Engineering and Mechanics
    • /
    • v.84 no.3
    • /
    • pp.311-321
    • /
    • 2022
  • In the buildings with long spans and high floors, such as logistics warehouses and semiconductor factories, it is difficult to install supporting posts under beams during construction. Therefore, the size of structural members becomes larger inevitably, resulting in a significant increase in construction costs. Accordingly, a prestressed hybrid wide flange (PHWF) beam with hollowed steel webs was developed, which can reduce construction costs by making multiple openings in the web of the steel member embedded in concrete. However, since multiple openings exist and prestress is introduced only into the bottom flange concrete, it is necessary to identify the shear resistance mechanism of the PHWF beam. This study presents experimental shear tests of PHWF beams with hollowed steel webs. Four PHWF beams with cast-in-place (CIP) concrete were fabricated, with key variables being the width and spacing of the steel webs embedded in the concrete and the presence of shear reinforcing bars, and web-shear tests were conducted. The shear behavior of the PHWF beam, including crack patterns, strain behavior of steel webs, and composite action between the prestressed bottom flange and CIP concrete, were measured and analyzed comprehensively. The test results showed that the steel web resists external shear forces through shear deformation when its width is sufficiently large, but as its width decreased, it exerted its shear contribution through normal deformation in a manner similar to that of shear reinforcing bars. In addition, it was found that stirrups placed on the cross section where the steel web does not exist contribute to improving the shear strength and deformation capacity of the member. Based on the shear behavior of the specimens, a straightforward calculation method was proposed to estimate the web-shear strength of PHWF beams with CIP concrete, and it provided a good estimation of the shear strength of PHWF beams, more accurate than the existing code equations.

The effect of heaving motion of multiple wave energy converters installed on a floating platform on global performance

  • Dongeun Kim;Yeonbin Lee;Yoon Hyeok Bae
    • Ocean Systems Engineering
    • /
    • v.13 no.4
    • /
    • pp.349-365
    • /
    • 2023
  • Targeting a floating wave and offshore wind hybrid power generation system (FWWHybrid) designed in the Republic of Korea, this study examines the impact of the interaction, with multiple wave energy converters (WECs) placed on the platform, on platform motion. To investigate how the motion of WECs affects the behavior of the FWWHybrid platform, it was numerically compared with a scenario involving a 'single-body' system, where multiple WECs are constrained to the platform. In the case of FWWHybrid, because the platform and multiple WECs move in response to waves simultaneously as a 'multi-body' system, hydrodynamic interactions between these entities come into play. Additionally, the power take-off (PTO) mechanism between the platform and individual WECs is introduced for power production. First, the hydrostatic/dynamic coefficients required for numerical analysis were calculated in the frequency domain and then used in the time domain analysis. These simulations are performed using the extended HARP/CHARM3D code developed from previous studies. By conducting regular wave simulations, the response amplitude operator (RAO) for the platform of both single-body and multi-body scenarios was derived and subsequently compared. Next, to ascertain the difference in response in the real sea environment, this study also includes an analysis of irregular waves. As the floating body maintains its position through connection to a catenary mooring line, the impact of the slowly varying wave drift load cannot be disregarded. To assess the influence of the 2nd-order wave exciting load, irregular wave simulations were conducted, dividing them into cases where it was not considered and cases where it was included. The analysis of multi-degree-of-freedom behavior confirmed that the action of multiple WECs had a substantial impact on the platform's response.

Development of a Method to Analyze Powering Performance of a Ship and its Application to Optimum Hull Form Design (선박(船舶)의 정수중(靜水中) 추진성능(推進性能) 해석(解析) 및 최적선형설계(最適船型設計)에의 응용(應用))

  • Seung-Il,Yang
    • Bulletin of the Society of Naval Architects of Korea
    • /
    • v.22 no.2
    • /
    • pp.35-48
    • /
    • 1985
  • The present work develops a method of evaluating thrust deduction and wake for different loads of the propeller using the concerted application of the theoretical tools and experimental techniques. It also shows the applicability of the new method to the design of optimum hull form. Firstly, the problem of hull-propeller interaction was analyzed in terms of inviscid as well as viscous components of the thrust deduction and wake. The wavemaking resistance of a hull and propeller were mathematically represented by sources on the hull surface and sink on the propeller plane, respectively. The strength of sink was determined by utilizing the radial distributions of propeller load and nominal wake. The resistance increment due to a propeller and the axial perturbation flow induced by the hull in the propeller plane were calculated. Especially, the inviscid component of the thrust deduction was calculated by subtraction the wavemaking resistance of a bare hull, the wavemaking resistance of a free-running propeller and the augmentation of propeller resistance due to hull action from the wavemaking resistance of the hull with a propeller. The viscous components of the thrust deduction and wake were estimated as functions of propeller load which were established by the propeller load varying test after deduction the calculated inviscid components. Secondly, an analysis method of powering performance was developed based on the potential theory and the propeller load varying test. The hybrid method estimates the thrust deduction, wake and propeller open-water efficiency for different propeller load. This method can be utilized in the analysis of powering performance for the propeller load variation such as the added resistance due to hull surface roughness, the added resistance due to wind, etc. Finally, the hybrid method was applied to the optimum design of hull form. A series of afterbody shapes was obtained by systematically varying the waterplane and section shapes of a parent afterbody without changing the principal dimensions, block coefficient and prismatic coefficient. From the comparison of the predicted results such as wavemaking resistance, thrust deduction, wake and delivered power, an optimum hull form was obtained. The delivered power of the optimized hull form was reduced by 5.7% which was confirmed by model tests. Also the predicted delivered power by the hybrid method shows fairly good agreement with the test result. It is therefore considered that the new analysis method of powering performance can be utilized as a practical tool for the design of optimum hull form as for the analysis of powering performance for the propeller load variation in the preliminary design stage.

  • PDF

Betaine-γ-aminobutyric Acid Transporter 1 (BGT-1/mGAT2) Interacts with the PDZ Domain of Munc-18 Interacting Proteins (Mints) (Betaine-γ-aminobutyric acid transporter 1 (BGT-1/mGAT2)과 Munc-18-interacting (Mint) 단백질의 PDZ 결합)

  • Kim, Sang-Jin;Jeong, Young-Joo;Choi, Sun-Hee;Choi, Chun-Yeon;Jun, Hee-Jae;Moon, Il-Soo;Seog, Dae-Hyun;Jang, Won-Hee
    • Journal of Life Science
    • /
    • v.22 no.9
    • /
    • pp.1159-1165
    • /
    • 2012
  • The action of neuronally released ${\gamma}$-aminobutyric acid (GABA) is terminated by uptake into the neurons by GABA transporters (GATs). The mechanism underlying the stabilization and regulation of GAT2 has not yet been elucidated. We used the yeast two-hybrid system to identify proteins that interact with and, thereby, regulate betaine-${\gamma}$-aminobutyric acid transporter 1 (BGT-1/mGAT2). We found an interaction between BGT-1/mGAT2 and Munc-18-interacting proteins (Mints). The "T-H-L" motif at the C-terminal end of BGT-1/mGAT2 was essential for the interaction with Mint2 in the yeast two-hybrid assay. Mint2 bound to the tail region of BGT-1/mGAT2, but not to other GAT members. When co-expressed in HEK-293T cells, Mint2 was co-immunoprecipitated with BGT-1/mGAT2. In addition, we demonstrated the cellular co-localization of BGT-1/mGAT2 and Mint2 in the cells. These results suggest that Mint2 contributes to the regulation of BGT-1/mGAT2.

Flexural Experiment of PSC-Steel Mixed Girders and Evaluation for Analyses on Tangentional Stiffness of Connection (프리스트레스트 콘크리트-강 혼합거더의 휨 실험 및 경계면 수평계수 분석)

  • Kim, Kwang-Soo;Jung, Kwang-Hoe;Sim, Chung-Wook;Yoo, Sung-Won
    • Journal of the Korea Concrete Institute
    • /
    • v.20 no.2
    • /
    • pp.231-237
    • /
    • 2008
  • This study was performed to evaluate joint behavior of prestressed concrete(PSC)-steel mixed girders through the flexural test of 14 beams according to embedded length, amount of reinforcing steel, stud arrangement, and prestressing force. All test beams were failed by turns of desertion of reinforcing steel, stud, and steel plate. From test results, prestressing force was more effective on performance of connection than stud arrangement and reinforcing steel. And the spacing of stud is also more effective than embedding length. This paper also presented 3D nonlinear analysis considering the slip of composite section as well as the static load tests of PSC-steel mixed girders. According to the slip modulus, the nonlinear analysis showed that the behavior of hybrid girders could be divided into three parts as full-composite, partial-composite and non-composite. However, the experimental results showed that the PSC-steel hybrid girders with shear connectors took the part of partial composite action in ultimate load stage. In addition, it was founded that stud shear connectors and welded reinforcements were contributed to improve the ultimate strength of hybrid girders for about 20%.

Insect Juvenile Hormone Antagonists as Eco-friendly Insecticides (친환경 살충제로서의 곤충 유충호르몬 길항제)

  • Choi, Jae Young;Je, Yeon Ho
    • Korean journal of applied entomology
    • /
    • v.61 no.1
    • /
    • pp.101-108
    • /
    • 2022
  • Because of their specificity to target insects and relatively low toxicity to non-target organisms, insect growth regulators (IGRs) have been regarded as attractive alternatives to chemical insecticides. Commercially available IGRs are classified into juvenile hormone agonists (JHAs), ecdysone agonists (EAs), and chitin synthesis inhibitors (CSIs) according to their mode of action. Recently, JH-mediated interaction of methoprene-tolerant (Met), which is JH receptor, and its binding partners have been replicated in vitro using yeast cells transformed with the Met and FISC/CYC genes of A. aegypti. Using this in vitro yeast two-hybrid β-galactosidase assay, juvenile hormone antagonists (JHANs) have been identified from various sources including chemical libraries, plants, and microorganisms. As juvenile hormone (JH) is an insect specific hormone and regulates development, reproduction, diapause and other physiological processes, JHANs fatally disrupt the endocrine signals, which result in abnormal development and larval death. These results suggested that JHANs could be efficiently applied as IGR insecticides with a broad insecticidal spectrum. This review discuses JH signaling pathway mediated by Met and future prospects of JHANs as environmentally benign IGR insecticides.