• Proceedings of the KSAR Conference
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• 2001.10a
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• pp.44-46
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• 2001

In vitro produced (IVP) embryos produced by in vitro fertilization (IVF) often exhibit wide variations in developmental competence and viability, considerably more than are exhibited by embryos that develop in vivo. These anomalies in IVP embryos may be due to heterogeneity of oocyte quality, suboptimal culture conditions, disturbances in gene expression, or most likely a combination of these factors (Ho et al., 1994; Roth et al., 1994; McKiernan and Bavister, 1998; Hasler, 1998; Schramm and Bavister, 1999; Doherty et al., 2000; Hyttel et al., 2000; Niemann and Wrenzycki, 2000; Wrenzycki et al., 2001). In research studies or in clinical applications with domesticated animals, cats, non-human primates and humans, oocytes used for IVF are usually collected from a heterogeneous cohort of ovarian follicles that include oocytes which normally might not be ovulated and/or are deficient in developmental competence. (omitted)

• Journal of Environmental Health Sciences
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• v.39 no.1
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• pp.1-18
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• 2013

Objectives: Although a great body of knowledge is available on the toxicity of bisphenol A (BPA), little is known about that of BPA alternatives, such as bisphenol analogues (BPs) or $Tritan^{TM}$ copolyesters. This review provides a summary of the available information on the toxicity of BPs and three components of $Tritan^{TM}$, with a special focus on endocrine disruption. Methods: We collected from the literature a battery of in vitro and in vivo assay data developed to assess endocrine disruption of four BPs (bisphenol AF, B, F, and S) and three major components of $Tritan^{TM}$ ((di-methylterephthalate (DMT), 1,4-cyclohexanedimethanol (CHDM), and 2,2,4,4-tetramethyl-1,3-cyclobutanediol (TMCD)). Results: Several alternative compounds were identified as possessing comparable or even greater endocrinedisrupting effects than BPA in in vitro and in vivo studies. Conclusions: Potential endocrine disruption of BPA alternatives requires further studies on health consequences in experimental animals and in humans following longer term exposure.

• Journal of the Semiconductor & Display Technology
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• v.20 no.2
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• pp.87-91
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• 2021

Various Cu ions are discharged into water from various industries, which results in a severe trouble for groundwater, soil, air, and eventually animals and humans. In this work, graphene oxide (GO) is introduced as a Cu removal absorber and the real-time monitoring method is demonstrated. The results show that GO is a very effective material to absorb Cu ions in the solution. In addition, the residual Cu ions in the solution is monitored via optical transmittance method, which well match with Inductively Coupled Plasma Mass Spectrometer (ICP-MS) analysis.

• Journal of Dairy Science and Biotechnology
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• v.39 no.4
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• pp.145-156
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• 2021

Antibiotics are used in many sectors, including the dairy industry, to prevent bacterial infections in humans, animals, and plants. When bacterial cells are exposed to stressors, such as antibiotic exposure, a subpopulation of the cells becomes dormant. This helps the pathogen to revive and reconstitute its pathogenicity. Thus, eradicating the dormant cells may be an effective strategy to reduce the development of antibiotic resistance in bacteria caused by the abuse of antibiotics. In recent years, a large number of indole-related compounds have been reported to eradicate persister cells. In this review, we provide a summary of the mechanisms of persister cell formation and resuscitation, and the ability of indole and substituted indoles to eradicate persister cells.

• Journal of Korean Foot and Ankle Society
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• v.27 no.4
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• pp.117-122
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• 2023

Collagen is the most common structural protein in the connective tissues of vertebrates, playing a crucial role in maintaining the tissue structure and wound healing. Atelocollagen retains the original properties of collagen but does not induce inflammatory cytokines. Atelocollagen is extracted from various animals and humans, with bovine-derived collagen being the most commonly used. The safety and efficacy of atelocollagen have been demonstrated through multiple studies, but further research will be needed in the field of orthopedics regarding its range of use and effects. Foot and ankle diseases have attracted little research attention, highlighting the need for further studies.

• YAKHAK HOEJI
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• v.48 no.1
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• pp.70-74
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• 2004

Bacillus polyfermenticus SCD which is commonly called as Bisroot (equation omitted) has been appropriately used for the treatment of long-term intestinal disorder's. This strain strongly inhibited against methicillin resistance Staphylococcus aureus (MRSA) and various pathogenic microorganisms. Effects of B. polyfermentius SCD administration on death rates and egg-laying rates in two groups of hens were investigated. This strain decreased the death rates of two groups by 16.26％ and 11.72％, respectively. Also this strain increased the egg-laying rates of those 2.74％ and 2.66％, respectively Clinical tests of B. polyfermenticus SCD administration to healthy adults showed not adverse effects but decreased glyceride concentration from 154.52 mg/dl to 135.41 mg/dl after two week administrations.

• Korean Journal of Veterinary Research
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• v.40 no.4
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• pp.747-753
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• 2000

Helicobacter species have commonly been isolated from the gastric mucosa of humans and animals, however have not been known its association with clinical signs. This study was aimed to detect and identify Helicobacter species in the canine stomach by urease test and polymerase chain reaction(PCR). A total of 87 dogs in Kangwon and Kyunggi areas from August, 1998 to June, 1999 were examined. The detection rate of Helicobacter species by urease test for fundal biopsy samples was 83.9%, and positive rate was increased as incubation time was increased. Helicobacter species was detected in the seventy seven dogs(88.5%) of total 87 dogs by PCR. The fifty five strains of the 77 strains of Helicobacter species were identified as H heilmannii and the three strains were identified as H felis by PCR, but the nineteen strains were not identified.

• The Korean Journal of Nuclear Medicine
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• v.35 no.6
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• pp.343-351
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• 2001

Cerebral post-ischemic hyperperfusion has been observed at the acute and subacute periods of ischemic stroke. In the animal stroke model, early post-ischemic hyperperfusion is the mark of recanalization of the occluded artery with reperfusion. In the PET studios of both humans and experimental animals, early post-ischemic hyperperfusion is not a key factor in the development of tissue infarction and indicates the spontaneous reperfusion of the ischemic brain tissue without late infarction or with small infarction. But late post-ischemic hyperperfusion shows the worse prognosis with reperfusion injury associated with brain tissue necrosis. Early post-ischemic hyperperfusion defined by PET and SPECT may be useful in predicting the prognosis of ischemic stroke and the effect of thrombolytic therapy.

• Korean Journal of Audiology
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• v.24 no.2
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• pp.53-60
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• 2020

Several novel animal models that represent the pathophysiological process of endolymphatic hydrops (ELH) of Meniere's disease (MD) have been developed. Animal models are important to identify and characterize the pathophysiology of ELH and to corroborate molecular and genetic findings in humans. This review of the current animal models will be useful in understanding the pathophysiology of and developing proper treatments for MD. Surgical animal models will be replaced by medication-induced animal models. Study models previously developed in guinea pigs will be developed in several smaller animals for ease of conducting molecular analysis. In this review, we provided updated resources including our previous studies regarding the current and desirable animal models for MD.

• Journal of Audiology & Otology
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• v.24 no.2
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• pp.53-60
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• 2020

Several novel animal models that represent the pathophysiological process of endolymphatic hydrops (ELH) of Meniere's disease (MD) have been developed. Animal models are important to identify and characterize the pathophysiology of ELH and to corroborate molecular and genetic findings in humans. This review of the current animal models will be useful in understanding the pathophysiology of and developing proper treatments for MD. Surgical animal models will be replaced by medication-induced animal models. Study models previously developed in guinea pigs will be developed in several smaller animals for ease of conducting molecular analysis. In this review, we provided updated resources including our previous studies regarding the current and desirable animal models for MD.