• International Journal of Stem Cells
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• 제15권2호
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• pp.195-202
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• 2022

Background and Objectives: Apoptosis is an outstanding determinant of glucocorticoid (GC)-induced osteonecrosis of the femoral head (ONFH). Human umbilical cord mesenchymal stem cells (hUC-MSCs) have been demonstrated to be associated with apoptosis in diseases models. However, the role of hUC-MSCs in GC-induced ONFH via regulating apoptosis still needs further study. Methods and Results: In the present study, a GC-induced ONFH model was built in vivo through a consecutive injection with lipopolysaccharide (LPS) and methylprednisolone. The necrosis and apoptosis of the femoral head was evaluated by histological and Terminal-deoxynucleoitidyl Transferase Mediated Nick End Labeling (TUNEL) assay. The level of collagen and TRAP positive cells were determined by Masson and TRAP staining, respectively. M1 macrophage polarization was assessed using immunofluorescence assay. The level of proinflammatory cytokines including tumor necrosis factor (TNF)-α, Interleukin (IL)-1β and IL-6 of femoral head was determined by enzyme-linked immunosorbent assay (ELISA) kits. The protein expression of AKT, mTOR, p-AKT and p-mTOR was detected using western blot assay. The results showed that hUC-MSCs treatment prominently promoted the GC-induced the decrease of the collagen level and the increase of TRAP positive cells. Besides, hUC-MSCs treatment decreased necrosis and apoptosis, macrophage polarization, the level of TNF-α, IL-1β and IL-6, the protein expression of p-AKT and p-mTOR, and the radio of p-AKT to AKT and p-mTOR to mTOR of femoral head in vivo. Conclusions: Therefore, the present study revealed that hUC-MSCs improved the necrosis and osteocyte apoptosis in GC-induced ONFH model through reducing the macrophage polarization, which was associated with the inhibition of AKT/mTOR signaling pathway.

• 간호행정학회지
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• 제8권4호
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• pp.551-561
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• 2002

Purpose : The purpose of the present study was to examine the causal relationships among head nurses' leadership (consideration oriented leadership, structure initiated leadership), nursing unit culture (human development culture, task development culture), and nurses' organizational commitment. Method : Four large general hospitals located in and around Seoul were selected to participate. The total sample of 286 registered nurses represents a response rate of 90 percent. Data for this study was collected from August to September in 2000 by questionnaire. Path analyses with LISREL program were used to test the fit of the proposed model to the data and to examine the causal relationships among variables. Result : Both the proposed model and the modified model fit the data adequately. The model revealed relatively high explanatory power. 52% of human development culture was explained by predicted variables and 44% of task development was explained by predicted variables; 47% of the organizational commitment was explained by predicted variables. In predicting developmental (both human and task) nursing unit culture, the findings of this study clearly demonstrated that head nurses' consideration oriented leadership might be the most important variable. The result also showed that head nurses' consideration oriented leadership might be the most important variable among the predicted variables in predicting organizational commitment. Conclusion : Based on the findings of this study, it was suggested that various studies, for example, matching leadership and nursing unit culture, were needed.

• 한국전자파학회논문지
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• 제10권7호
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• pp.1095-1103
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• 1999

현재 helix와 monopole로 구성되는 안테나를 갖는 수납형 전화기(retractble phone)가 셀룰라 이동통신에서 가장 널리 사용되고 있다. 그러나 안테나의 monopole의 길이가 약 $\lambda$/4이므로, 강한 복사 전기장이 전화기를 사용하는 인체 두부의 외이 주변에 주로 분포한다. 이러한 전기장 분포는 두부 내에 매우 높은 국부 SAR(specific abs$\alpha$ption rate)을 야기한다. 본 논문은 이동통신단말기의 안테나 배치가 반대인 전화기 형상에 대한 두부 내 전자파 흡수율을 기존의 단말기 형상의 것과 비교, 고찰한다. 이것은 단말기 옴체의 상부가 아닌 바닥 에 안테나를 배치하는 것이다. 인체와 단말기 모델을 포함하는 계산 공간의 시간-평균 전자기장 분포를 얻기 위해 시간영역 유한차분( FDTD) 기법을 사용하였다. 그리고 SAR 분포와 국부 SAR 값이 시간-명균 전기장 분포로부터 계산되었다. 실제 상황을 고려하기 위해 해부학적 인체 두부 모델과 근사된 사용자 손이 고려되었 다. 분석된 데이터는 안테나의 이 같은 배치가 인체 두부 내에 국부 SAR을 상당히 감소시킴을 보인다.

• 대한전자공학회논문지TC
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• 제37권11호
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• pp.32-41
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• 2000

두부 형상이 국내 표준에 근접하는 한 자원자 두부의 MR 및 CT 영상에 바탕하여 새로운 해부학적 두부 모델을 구현하였다. 서로 다른 형상을 갖는 두부의 전자파 비흡수율(SAR)을 비교하기 위해 두 가지의 해부학적 두부 모델의 SAR을 계산하였다. 하나는 구현된 모델이고 다른 하나는 미국 National Library Medicine에서 제작된 흑인 모델이다. 계산 공간 내의 두부와 이동통신단말기는 CENELEC과 FCC 지침의 접촉위치가 되도록 배치하였다. 얻어진 결과로부터 두부의 크기가 작을수록 두부 전체 평균 SAR은 높아짐을 볼 수 있었으나 1g 또는 10g 평균의 국부 SAR은 두부의 크기보다는 외이의 형상에 더 의존하는 것으로 보인다.

• 한국의류학회지
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• 제46권6호
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• pp.1128-1141
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• 2022

Due to increased interest in safety in sports, leisure, industries, and daily life; the demand for products that protect the head is increasing. As a preparatory study for the development of head protection for head injury prevention, this study analyzed patents and utility models related to head protection products such as industrial safety helmets, vehicle helmets, and sports protection gear. For this study, 368 patents and utility models for head protection products searched through WipsOn were selected and analyzed by application year, function, application, protection area, main material, and subject. From the analytic results of this study, the quantitative and qualitative flow and characteristics of developing technology related to head protection products were identified. Through the trend of current technology, it provided data to seek the development direction in the future. The significance of this study is to secure objective data to establish a road map for creating new Intellectual Property for head protection products.

• 한국멀티미디어학회논문지
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• 제19권12호
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• pp.1927-1935
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• 2016

This paper propose a framework for human body parts in RGB-D image. We conduct tasks of obtaining person area, finding candidate areas and local detection in order to detect hand, foot and head which have features of long accumulative geodesic distance. A person area is obtained with background subtraction and noise removal by using depth image which is robust to illumination change. Finding candidate areas performs construction of graph model which allows us to measure accumulative geodesic distance for the candidates. Instead of raw depth map, our approach constructs graph model with segmented regions by quadtree structure to improve searching time for the candidates. Local detection uses HOG based SVM for each parts, and head is detected for the first time. To minimize false detections for hand and foot parts, the candidates are classified with upper or lower body using the head position and properties of geodesic distance. Then, detect hand and foot with the local detectors. We evaluate our algorithm with datasets collected Kinect v2 sensor, and our approach shows good performance for head, hand and foot detection.

• 한국전자파학회논문지
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• 제12권3호
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• pp.409-426
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• 2001

본 논문은 유한차분 시간영역 해석법(Finite-Difference Time-Domain Method)을 사용하여 900 MHz용 휴대폰으로부터 방출된 전파의 인체 두부(頭部)에 흡수된 전력량을 산출하였고, 흡수전력으로 인한 두부내의 온도 상승량을 계산하였다. 이를 위하여 인체두부를 5층 매질로 모델링하였고, 휴대폰은 금속상자에 부착된 모노폴안테나로 모델링하였다. 모델링에 사용된 인체두부와 휴대폰의 크기는 상용의 값을 사용하였다. 사용된 모노폴 안테나의 길이는 8.16 cm이고, 휴대폰의 출력은 상용 900 MHz의 600 mW을 사용하였다. 설정된 모델링하에서 인체의 위해(危害)정도를 알려주는 지수는 1 g, 10 g 평균 北 흡수율(SAR-Specific Absorption Rate)의 분포를 계산하였고 이에 따른 1g, 10 g 평균 온도 상승량을 계산하였다. 그 결과 비흡수율이 최대가 되는 지점은 인체 두부의 피부 부분이었고 최대 온도 증가 위치는 이보다 안쪽부분에서 나타났다. 인체 두부와 휴대폰의 이격거리에 따른 SAR과 온돈 상승량을 계산하였다.

• 대한의용생체공학회:의공학회지
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• 제20권4호
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• pp.485-493
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• 1999

Human can generate various posture and motion with nearly 350 muscle pairs. From the viewpoint of mechanisms, the human skeleton mechanism represents great kinematic and dynamical complexity. Physical and behavioral fidelity of human motion requires dynamically accurate modeling and controling. This paper describes a mathematical modeling, and dynamic simulation of human body. The human dynamic model is simplified as a rigid body consisting of 18 actuated degrees of freedom for the real time computation. Complex kinematic chain of human body is partitioned as 6 serial kinematic chains that is, left arm, right arm, support leg, free leg, body, and head. Modeling is developed based on Newton-Euler formulation. The validity of proposed dynamic model, which represents mathematically high order differential equation, is verified through the dynamic simulation.

• 한국의류산업학회지
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• 제12권6호
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• pp.812-820
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• 2010

The objectives of this study were to classify the head shapes of Korean men and to suggest computer tomography as a new body measurement method. The 23 head measurement items of 760 men, aged more than 18 in Sizekorea 2004 database were used to analyze, measured by using statistical methods. Factor analysis, cluster analysis and duncan test were performed using these data. Through factor analysis, 5 factors were extracted upon factor scores and those factors comprised 70.91% for the total variances. The head and face shapes were categorized as 5 types-triangle, round, oval, long, rectangle. We decided for the type 1(triangle) to standard head shape since this type was the most observed. 21 participants were measured using computed tomography(CT). The measured data of skin and skeleton and the standard head shapes were illustrated.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2002년도 춘계학술대회 논문집
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• pp.536-539
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• 2002

The reverse engineering (RE) technology can quickly generate 3D point cloud data of an object by capturing the surface of a model using a 3D scanner. In the rapid prototyping (RP) technology, prototypes are rapidly produced from 3D CAD models in a layer-by-layer additive basis. In this paper, a physical human head shape is duplicated using a new RP process, the Transfer-type Variable Lamination Manufacturing process using expandable polystyrene foam sheet (VLM-ST), after the point cloud data of a human head shape measured from 3D SNX scanner are converted to STL file. From the duplicated human head shape, it has been shown that the VLM-ST process in connection with the 3D scanner is a fast and efficient process in that shapes with free surface, such as the human head shape, can be duplicated with ease. Considering the measurement time and the shape duplication time, the use of 3D SNX scanner and the VLM-ST process is expected to reduce the lead-time fur the development of new products in comparison with the other existing RE-RP connected manufacturing systems.