• Title/Summary/Keyword: Human diet

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L-Carnitine Reduces Obesity Caused by High-Fat Diet in C57BL/6J Mice

  • Mun, Eun-Gyeng;Soh, Ju-Ryoun;Cha, Youn-Soo
    • Food Science and Biotechnology
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    • v.16 no.2
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    • pp.228-233
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    • 2007
  • This study evaluated the effects of carnitine supplementation on obesity caused by a high-fat diet in C57BL/6J mice. The mice were fed a normal diet (ND), high-fat diet (HD), or carnitine-supplemented (0.5% of diet) high-fat diet (HDC) for 12 weeks. The results showed that body weight, energy intake, and feed intake were lower in the HDC group than the control groups. Acid-soluble acylcarnitine (A SAC), acid-insoluble acylcarnitine (AIAC), and total carnitine (TCNE) in the serum and liver were significantly higher in the HDC group. Hepatic carnitine palmitoyl transferase-I activity was significantly higher in the HDC group than the control groups. Acyl-coA synthetase (ACS) and carnitine palmitoyl transferase-I (CPT-I) mRNA expression in the liver was highest in the HDC group, however hepatic acetyl-coA carboxylase (ACC) mRNA expression in this group was lowest. Serum leptin levels and abdominal fat weight were lowest in the HDC group. We concluded that L-carnitine supplementation diminished the risk of obesity caused by a high-fat diet.

Effects of Cell Cultured Acanthopanax senticosus Extract Supplementation and Swimming Exercise on Lipid and Carnitine Profiles in C57BL/6J Mice Fed a High Fat Diet

  • Park, Jeong-Eun;Soh, Ju-Ryoun;Rho, Jeong-Ok;Cha, Youn-Soo
    • Food Science and Biotechnology
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    • v.16 no.6
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    • pp.894-901
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    • 2007
  • This study investigated the effects of cell cultured Acanthopanax senticosus extract (ASE) supplementation and swimming exercise on lipid profiles and carnitine concentrations in C57BL/6J mice fed high fat diets. Male C57BL/6J mice (n=50), aged 4 weeks, were divided into 5 groups based on exercise and/or ASE supplementation (0.5 g/kg of body weight): normal diet (N-C), high fat diet (H-C), high fat diet non-supplement & exercise (H-NSE), high fat diet supplement & no exercise (H-SNE), high fat diet supplement & exercis (H-SE). Liver nonesterified carnitine (NEC) was significantly higher in the H-SNE group than in the H-C group, and liver total carnitine (TCNE) levels were significantly higher in the H-SNE group than in the H-NSE and H-SE groups. Liver and muscle carnitine palmitoyltransferase-I (CPT-I) mRNA levels tended to be higher with ASE supplementation and/or exercise. These results suggest that supplementation with ASE and/or exercise might have a role in improving lipid oxidation.

Analyses on the dieters' characteristics and the factors determining diet practice in college (대학생의 다이어트 실행 특성 분석 및 실행 여부에 영향을 미치는 요인 연구)

  • Kim, Mee-Ra;Kim, Hyo-Chung
    • Korean Journal of Human Ecology
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    • v.17 no.3
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    • pp.521-532
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    • 2008
  • The study aims to examine college students' practice characteristics related to diet and to identify factors determining their diet practice. The subjects were college students (N=387) in Youngnam region; a questionnaire survey was conducted in May, 2007. The data were analyzed by SPSS Windows. The results are as follows: first, the ratio of female students going on a diet is higher than that of male students. Second, according to the BMI, female students more regard themselves as being overweight than male students do, although they are underweight or normal weight. Third, in the interest in diet, almost half the students think of themselves as being "somewhat" or "much" concerned about diet. Fourth, the binary logistic regression analysis shows that the significant factors affecting female students' diet practice are the variables of "grade", "interest in diet", "body image evaluation in the individuals", "information/education requirement on dietary guidelines", and "necessity to go on a diet". On the other hand, the significant variables affecting male students' diet practice are the variables of "to take diet- or health-related courses", "interest in diet", "diet knowledge", and "diet practice".

Fermented Kochujang Supplement Shows Anti-obesity Effects by Controlling Lipid Metabolism in C57BL/6J Mice Fed High Fat Diet

  • Koo, Bon-Sun;Seong, So-Hui;Kown, Dae-Young;Sohn, Hee-Sook;Cha, Youn-Soo
    • Food Science and Biotechnology
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    • v.17 no.2
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    • pp.336-342
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    • 2008
  • The aim of the present study was to assess the anti-obesity effects of fermented kochujang supplement in C57BL/6J mice. Thirty mice were divided into 3 groups; normal diet control group (ND), high fat diet control group (HD), and high fat diet plus kochujang supplemented group (HDK). Results were as follows: 1. Fennented kochujang supplement in high fat diet decreased body weight and epidydimal and back fat weight compared to non-supplement in HD group. 2. Lipid content and blood glucose level were lower in HDK group than HD group. 3. Fermented kochujang supplement increased mRNA level of lipolytic genes such as acyl-CoA synthetase (ACS), carnitine palmitoyltransferase-1 (CPT-1), and uncoupling proteins-1 (UCP-1) expression, whereas decreased mRNA level of adipogenic genes such as acetyl CoA carboxylase (ACC) expression. These findings suggest that fermented kochujang supplement in high fat diet normalized body weight, epididymal and back fat weight, lipid content, and blood glucose levels through controlling lipid metabolism and provides basic information on the control of obesity.

Genistein Combined with Exercise Improves Lipid Profiles and Leptin Levels in C57BL/6J Mice Fed a High Fat Diet

  • Seong, So-Hui;Ahn, Eun-Mi;Sohn, Hee-Sook;Baik, Sang-Ho;Park, Hyun-Woo;Lee, Sang-Jun;Cha, Youn-Soo
    • Food Science and Biotechnology
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    • v.16 no.6
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    • pp.910-917
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    • 2007
  • The aim of this study is to determine the anti-obesity effects of genistein and exercise, separately and in combination, in mice. Fifty male C57BL/6J mice were divided into 5 treatment groups: normal diet (ND), high fat diet (HD), high fat diet with exercise (HD+Ex), high fat diet with 0.2% genistein (HD+G), high fat diet with 0.2% genistein, and exercise (HD+G+Ex). They were allowed free access to feed and water, and exercised mice engaged in swimming on a regular basis for 12 weeks. Genistein supplemented mice gained less weight, had lower energy intake, better lipid profiles, and lower leptin than the HD mice. Furthermore, when genistein was combined with exercise (HD+G+Ex) the effects were even greater. HD, HD+Ex, and HD+G mice exhibited increased hepatic CPT-1 mRNA expression. Therefore, genistein and exercise has anti-obesity effects, as shown by changes in body weight, fat accumulation, energy intake, and leptin levels.

Effects of Diet Therapy Related to Constitution on Over Weight and Obese Human (체질에 따른 식사요법이 체중과다 및 비만에 미치는 영향)

  • 허봉수;백숙은
    • Journal of the East Asian Society of Dietary Life
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    • v.8 no.3
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    • pp.261-270
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    • 1998
  • This study was conducted in order to investigate the effect of diet therapy on over weight and obese humans in Korea Subseng Research Institute from January 1, 1994 to August 31, 1997. The constitutions of subjects were classified mild negative, strong negative, mild positive and strong positive respectively by ecology and O-ring test. These results were obtained from the subjects who practiced at least 75% diet therapy recommended for over weight and obese human for 14~400days. The constitutions of over weight and obese human by Relative Body Weight (RBW$\geq$110%) were 89 mild negative humans, 62 strong negative humans, 56 mild positive humans and 30 strong positive humans. The constitutions of over weight and obese human by Body Mass Index(BMI$\geq$25) were 77 mild negative humans, 50 strong negative humans 46 mild positive humans and 23 strong positive humans. The negative subjects were higher than the positive subjects on over weight and obese humans. The diet therapy related to constitiution on over weight and obese humans showed RBW reduction of 6.73$\pm$0.53 on mild negative human, 7.78$\pm$1.69 on strong negative human, 6.94$\pm$0.76 on mild positive human, and 7.80$\pm$1.15 on strong positive human at p<0.001 by student paired t-test. The diet therapy related to constitution on over weight and obese humans showed BMI reduction of 1.47$\pm$0.12 on mild negative humans, 1.24$\pm$0.11 on strong negative humans, 1.59$\pm$0.17 on mild positive humans, and 1.66$\pm$0.30 on strong positive humans at p<0.001 by student paired t-test.

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Diet- Related Behaviors and Food Preference of Indonesian (인도네시아인의 식생활 양상 및 선호음식 분석)

  • Park, Chan Yoon;Han, Sung Nim
    • Korean Journal of Community Nutrition
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    • v.19 no.1
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    • pp.41-50
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    • 2014
  • As Korea is moving toward multicultural society, the number of Muslim, whose religion has a great influence on diet-related behaviors, is increasing in Korea. Since the number of immigrants from Indonesia ranks within top ten in Korea and Indonesia is one of the most representative Islamic countries in Asia, understanding the diet-related behaviors and food preferences of Indonesians is needed. This study was conducted to investigate diet-related behaviors, factors affecting the diet-related perceptions, and food preferences of the Indonesians. The subjects included 500 Indonesians dwelling in Jakarta, Indonesia. About ninety % of the subjects in this study were Muslims. They did not eat pork and dog meat for religious reason and they practiced fasting during Ramadan period. Indonesians avoided pineapple, durian, and hot foods during pregnancy and usually ate vegetables and fruits after birth, which seemed to be due to sociocultural influence. Among the subjects, 21.5% were obese and major health problems reported were hypertension and hyperlipidemia. Their preference for fried food items might have contributed to health problems. Subjects had meals mostly at home (2.3 times/day) and dined out occasionally (1.2 times/week) at Indonesian restaurants (56.6%) or family restaurants (21.0%). In conclusion, Indonesians had home-based and native food-oriented dietary life with strong religious and sociocultural influence on food choices. Further research on specific nutrient intake analysis is needed to better understand and to improve dietary life of Indonesians in Korea.

Analysis on Awareness and Practices for Diet according to Lifestyles of College Students (대학생의 라이프스타일 유형에 따른 다이어트 인식도 및 실천 행동 분석)

  • Kim, Hyo-Chung;Kim, Mee-Ra
    • Korean Journal of Human Ecology
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    • v.19 no.1
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    • pp.157-165
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    • 2010
  • The purpose of this study was to investigate the awareness and practices for diet according to the lifestyles of college students in Youngnam region. The data were collected by self-administered questionnaires during May 2007. One hundred-ninety samples were analyzed by SPSS Windows. Frequencies, Cronbach's alpha, factor analysis, cluster analysis, one-way analysis of variance, Duncan's multiple range test and chi-square test were conducted. The results were as follows. Lifestyles were categorized into four factors by factor analysis: popularity-seeking type, body-management-seeking type, convenience-seeking type and healthy-seeking type. In addition, the respondents belonged to one of four groups by cluster analysis: body-management-seeking group, popularity-seeking group, convenience-seeking group, and healthy-seeking group. There were significant differences in perception about individual body images, concern of diet, awareness of diet necessity and knowledge and practices for diet among the four groups. That is, the body-management-seeking group showed the highest levels of concern of diet, awareness of diet necessity and the practice of fasting therapy. Additionally, the healthy-seeking group showed the highest level of practice of exercise therapy.

Effects of High-Protein Diet and/or Resveratrol Supplementation on the Immune Response of Irradiated Rats

  • Kim, Kyoung Ok;Park, Hyunjin;Kim, Hyun-Sook
    • Preventive Nutrition and Food Science
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    • v.19 no.3
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    • pp.156-163
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    • 2014
  • We investigated the effects of a high-protein diet and resveratrol supplementation on immune cells changes induced by abdominal irradiation in rats. Female Wistar rats were divided into 5 groups: 1) control diet, 2) control diet with irradiation 3) 30% high-protein diet with irradiation, 4) normal diet with resveratrol supplementation and irradiation, and 5) 30% high-protein diet with resveratrol supplementation and irradiation. We measured blood protein and albumin concentrations, lipid profiles, white blood cell (WBC) counts, proinflammatory cytokine production, and splenocyte proliferation in rats that had been treated with a 17.5 Gy dose of radiation 30 days prior. A high-protein diet affected plasma total cholesterol and very low density lipoprotein-cholesterol levels, which were increased by the radiation treatment. In addition, the lymphocyte percentage and immunoglobulin M (IgM) concentration were increased, and the neutrophil percentage was decreased in rats fed a high-protein diet. Resveratrol supplementation decreased the triglyceride (TG) level, but increased the IgM concentration and splenocyte proliferation. Proinflammatory cytokine production was lower in rats fed a high-protein diet supplemented with resveratrol than in rats fed a control diet. The results of the present study indicate that high-protein diets, with or without resveratrol supplementation, might assist with recovery from radiation-induced inflammation by modulating immune cell percentages and cytokine production.

Effects of Cellulose and Pectin on Postprandial Blood Glucose and Plasma Lipid Concentration (셀룰로오스 및 펙틴이 식후 혈당과 혈장 지질 농도에 미치는 영향)

  • Lee Sun-Woo;Ro Hee-Kyong;Choi In-Seon;Oh Seune-Ho
    • Journal of Nutrition and Health
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    • v.39 no.3
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    • pp.244-251
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    • 2006
  • The purpose of this study was to observe the effects of cellulose and pectin on glucose and plasma lipid concentrations in healthy women. Eight female collage students were participated voluntarily. All subjects received a fiber-free control diet (CD), cellulose diet (CED), pectin diet (PTD) with each diet for a period of three days with a 4 day interval. The food intake of subjects were monitored every day and plasma level of glucose, triglyceride, total cholesterol were determined at last day. Blood glucose, plasma triglyceride, total cholesterol were measured at fasting state and 30, 60, 90, 120, and 180 minute after consuming each diet. Plasma glucose concentrations (AUC: Area Under the Curve) of pectin diet was $122.7{\pm}4.0mg/dl$ and that of cellulose diet was $147.6{\pm}8.4mg/d$, but they were significantly lower than in comparison with those of control diet ($197.1{\pm}11.6mg/dl$) (p<0.05) Plasma triglyceride concentrations of the CED ($-83.9{\pm}22.2mg/dl$) PTD ($-9.7{\pm}26.1mg/dl$) showed gradual decrease after each test diet feeding but not significantly different in each dietary fiber added diet (p<0.05). Plasma cholesterol concentrations of the CD was not significantly different in PTD, but PTD was significantly lower than the CED until 3 hours after consuming each test meal (p<0.05). In conclusion, in spite of total cholesterol was reduced only by pectin, glucose and triglyceride were lower than control diet in dietary fiber intake. But there were no significant differences each dietary fiber.