• Title/Summary/Keyword: Human case

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Imported human babesiosis in the Republic of Korea, 2019: two case reports

  • Hyun Jung Kim;Min Jae Kim;Hyun-Il Shin;Jung-Won Ju;Hee-Il Lee
    • Parasites, Hosts and Diseases
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    • v.61 no.1
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    • pp.72-77
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    • 2023
  • Human babesiosis is a tick-borne disease induced by the genus Babesia and has been significantly reported in the Republic of Korea. This report shows the cases of 2 patients with human babesiosis who traveled to the USA in 2019. The 2 patients experienced fever and had travel histories to babesiosis-endemic regions. The diagnoses of both cases were verified by the identification of Babesia-infected red blood cells on blood smears. One patient was found to be infected with Babesia microti using polymerase chain reaction (PCR) for 18S rRNA, which discovered the phylogenetic link to the B. microti strain endemic in the USA. The 2 patients recovered from fever with subsequent hemoparasite clearance. Babesiosis could be diagnosed in anyone with histories of travel to babesiosis-endemic countries and tick bites. Furthermore, Babesia-specific PCR is required for determining geno-and phenotypic characteristics.

Development of human-in-the-loop experiment system to extract evacuation behavioral features: A case of evacuees in nuclear emergencies

  • Younghee Park;Soohyung Park;Jeongsik Kim;Byoung-jik Kim;Namhun Kim
    • Nuclear Engineering and Technology
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    • v.55 no.6
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    • pp.2246-2255
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    • 2023
  • Evacuation time estimation (ETE) is crucial for the effective implementation of resident protection measures as well as planning, owing to its applicability to nuclear emergencies. However, as confirmed in the Fukushima case, the ETE performed by nuclear operators does not reflect behavioral features, exposing thus, gaps that are likely to appear in real-world situations. Existing research methods including surveys and interviews have limitations in extracting highly feasible behavioral features. To overcome these limitations, we propose a VR-based immersive experiment system. The VR system realistically simulates nuclear emergencies by structuring existing disasters and human decision processes in response to the disasters. Evacuation behavioral features were quantitatively extracted through the proposed experiment system, and this system was systematically verified by statistical analysis and a comparative study of experimental results based on previous research. In addition, as part of future work, an application method that can simulate multi-level evacuation dynamics was proposed. The proposed experiment system is significant in presenting an innovative methodology for quantitatively extracting human behavioral features that have not been comprehensively studied in evacuation. It is expected that more realistic evacuation behavioral features can be collected through additional experiments and studies of various evacuation factors in the future.

A Case Study on Aircraft Accidents Due to Air Traffic Controller's Human Error - Applying TEM (Threat & Error Management) Analysis - (항공교통관제사의 휴먼에러에 기인한 국내외 항공기 사고 사례연구 - TEM(Threat & Error Management) 분석법을 적용하여 -)

  • Kim, Jung-Bin;Park, Sung-Sik
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.29 no.4
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    • pp.124-133
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    • 2021
  • The airline industry has been growing steadily since 2016 with more than 100 million air passengers, renewing the largest number of air passengers every year. Increasing air demand leads to an increase in air traffic in limited airspace, increasing the likelihood of accidents between aircraft. Due to the massive human and material damage caused by a single mistake, aviation safety is being heavily focused around the world to efficiently use limited airspace. Studies related to various human factors are underway as most of the aviation accidents are found to be caused by human factors, but research on human factors by controllers is insufficient while they are active in terms of control and operation. Given that 82% of air accidents caused by controllers are caused by human error, the importance of management of human error and changes in perception are urgently needed. This study aims to understand the seriousness of the controller's human error by analyzing the accident cases caused by the controller's human error using TEM to identify threats and errors and derive common human factors.

Conformation and Linkage Studies of Specific Oligosaccharides Related to H1N1, H5N1, and Human Flu for Developing the Second Tamiflu

  • Yoo, Eunsun
    • Biomolecules & Therapeutics
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    • v.22 no.2
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    • pp.93-99
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    • 2014
  • The interaction between viral HA (hemagglutinin) and oligosaccharide of the host plays an important role in the infection and transmission of avian and human flu viruses. Until now, this interaction has been classified by sialyl(${\alpha}2-3$) or sialyl(${\alpha}2-6$) linkage specificity of oligosaccharide moieties for avian or human virus, respectively. In the case of H5N1 and newly mutated flu viruses, classification based on the linkage type does not correlate with human infection and human-to-human transmission of these viruses. It is newly suggested that flu infection and transmission to humans require high affinity binding to the extended conformation with long length sialyl(${\alpha}2-6$)galactose containing oligosaccharides. On the other hand, the avian flu virus requires folded conformation with sialyl(${\alpha}2-3$) or short length sialyl(${\alpha}2-6$) containing trisaccharides. This suggests a potential future direction for the development of new species-specific antiviral drugs to prevent and treat pandemic flu.

ENCODE: A Sourcebook of Epigenomes and Chromatin Language

  • Yavartanoo, Maryam;Choi, Jung Kyoon
    • Genomics & Informatics
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    • v.11 no.1
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    • pp.2-6
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    • 2013
  • Until recently, since the Human Genome Project, the general view has been that the majority of the human genome is composed of junk DNA and has little or no selective advantage to the organism. Now we know that this conclusion is an oversimplification. In April 2003, the National Human Genome Research Institute (NHGRI) launched an international research consortium called Encyclopedia of DNA Elements (ENCODE) to uncover non-coding functional elements in the human genome. The result of this project has identified a set of new DNA regulatory elements, based on novel relationships among chromatin accessibility, histone modifications, nucleosome positioning, DNA methylation, transcription, and the occupancy of sequence-specific factors. The project gives us new insights into the organization and regulation of the human genome and epigenome. Here, we sought to summarize particular aspects of the ENCODE project and highlight the features and data that have recently been released. At the end of this review, we have summarized a case study we conducted using the ENCODE epigenome data.

Imaging a scene from experience given verbal experssions

  • Sakai, Y.;Kitazawa, M.;Takahashi, S.
    • 제어로봇시스템학회:학술대회논문집
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    • 1995.10a
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    • pp.307-310
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    • 1995
  • In the conventional systems, a human must have knowledge of machines and of their special language in communicating with machines. In one side, it is desirable for a human but in another side, it is true that achieving it is very elaborate and is also a significant cause of human error. To reduce this sort of human load, an intelligent man-machine interface is desirable to exist between a human operator and machines to be operated. In the ordinary human communication, not only linguistic information but also visual information is effective, compensating for each others defect. From this viewpoint, problem of translating verbal expressions to some visual image is discussed here in this paper. The location relation between any two objects in a visual scene is a key in translating verbal information to visual information, as is the case in Fig.l. The present translation system advances in knowledge with experience. It consists of Japanese Language processing, image processing, and Japanese-scene translation functions.

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The Effect of Frequent Change in Railway Driving Regulations on Human Error (철도운전관련규정의 잦은 변경이 휴먼에러에 미치는 영향)

  • Kim, Jin-Tae;Shin, Tack-Hyun
    • Journal of the Korea Safety Management & Science
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    • v.16 no.2
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    • pp.19-29
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    • 2014
  • Korean societal concern for the train accidents is fast and widely increasing with an ever-increasing demand and use for KTX. Most of these train accidents are inclined to be caused by human error. Experts used to attribute the causes of human error to the defects in various aspects such as technology, organizational system, practices, corporate culture, and/or human resource itself. Among the diverse causes of human error, an important one, even though it was rarely focused, may be the issue of impact of rule or procedure change on human error. Giving attention to the implicit importance of this issue, this study intends to highlight the theme of frequent procedure change in railway driving manual as a critical factor of human error. To attain this purpose mentioned above, dual methodologies were adopted. One is to qualitatively analyze the real cases of procedure change in relevant manuals followed by the incident case(passing the station scheduled to stop) happened lately. Another is to quantitatively perform statistical analysis based on questionnaires received from 224 train drivers. Results show that frequent changes in internal affairs procedure is or may be an important factor causing stress and human error from train drivers.

Appropriation of Human Resources into Human Assets and Its Typology (인적자원의 인적자산화 과정과 자산유형)

  • Jeong, Kioh
    • Journal of Service Research and Studies
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    • v.9 no.2
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    • pp.77-88
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    • 2019
  • Appropriation means the process of transforming resources to property. John Locke earlier investigated the appropriation process of natural resources into the land property, which grounded the jurisprudential base of the private ownership of the land. In the same way human resources are transformed into the human assets. Appropriation process, very rarely studied so far, in this case of human property is the focus of this paper. The appropriation of intangible property is by far easier than the appropriation of tangible property. Learning is a process of embodiment, which naturally mean the process of appropriation. For the material resources which exist out of human body, appropriation necessary need special philosophical and institutional justification. In the process appropriation for intangibles, investigator found, appropriator and learner either can be same, or can be differentiated. In the former case substantial human assets are created while in the latter relational human assets are built. After the discussion of appropriation process, Investigator proceeds to the problem of visualizing the invisibles. Evaluation and assessment issue were discussed in this perspective. Qualification system is particularly noted as a system to regulate substantial human assets including their issuing and registration. The work done in this paper would contribute in understanding the law of education and the law of qualification.

Refusal of care by chronically and terminally ill patients : An ethical problem faced by nurses (간호사의 간호 제공 의무와 말기 환자의 간호 거부에 관련된 윤리 문제에 관한 연구)

  • 엄영란;홍여신
    • Journal of Korean Academy of Nursing
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    • v.24 no.2
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    • pp.190-205
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    • 1994
  • Respect for human life and respect for human dignity are two basic values to which organized nursing has urged its members to adhere in their service to mankind. Thus it is the nurses’ duty to provide health care in support of sustenance of life and to pay respect for the patient’s right to dignity. In practice, however, nurses may experience dilemmas between these duties much due to the de velopment of modern advanced techniques. These dilemmas have become more complex and difficult to resolve. Nurses are often faced with situations in which the terminally ill refuse professional care, posing serious conflicts between respect for human life and respect for human rights to self-determination. In such cases, resolution of the problem is not a simple matter, thus requires intensive study into the ethical questions related to the situation. The purpose of this study was to identify ethical problems that nurses experience in caring for terminally ill patients and explore the ways to the resolution of problems within the context of the situations. The methodology used for the study was a case study method which ‘New Casuistry’ proposed by Jonsen & Toulmin(1988) and the ‘Specified Principlism’ proposed by Degrazia(1992) as an alternative to old deductive and intuitive method. Cases were developed through semistructured indepth interviews according to the casutistry method. A total of seven nurses were interviewd who were caring for therminally ill patients. Four cases out of a total 14 cases were related to the topic. Through the case analysis it became evident that nurses appreciated other values more often than respect for the patient’s right to self-determination. These other values were convenience and efficiency in nursing practice in case 1, preservation of life above all other values in case 2, provision of nursing care to fulfill the nurse’s professional obligation at most in case 3, and respect for the family’s demand against the patient’s wish in case 4. This study showed that the most important ethical problems were conflict between respect for the patient’s right to self-determination and sustenance of life for the fulfillment of professional obligation. For this problem, benefit /burden analysis from the perspective of the patient and family for the promotion of patient’s wellbeing may be a way to resolve the conflict. Further, through these analysis it was shown that physicians’ and families’ opinions dominated in the decision - making and the opinions of nurses’ and patients’ tended not to be reflected. Thus the patient's right to his or her care was not readily respected. To solve this problem. nurses should make efforts to communicate reciprocally with their patients, family members and physicians in an effort to respect for their patient’s rights to life and diginity from the point of view and values of the patient. It is also important that nurses provide good basic nursing care up to the time of death regardless of decisions about providing or not aggressive treat-ment for chronically and terminally ill patients.

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A Study on Divided Shirt Pattern -Fro influential Factor on the Appearance and the Function- (디바이디드 스커트(Divided Shirt)의 패턴 연구 -외관과 기능성에 영향을 미치는 요인을 중심으로-)

  • 서미아;이미옥
    • The Research Journal of the Costume Culture
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    • v.5 no.4
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    • pp.112-129
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    • 1997
  • This research, focused on the curved of the lower body, designated abdomen and hip gradient, crotch depth and crotch width the factors for which are able to influence on the appearence and the function of Divided Skirt and analized the changes when that were applied to a real pattern, and so the purpose of this research is to show the basic documents needed to design a Divided Skirt pattern fitting with the wear purpose and usage. The following are the results of this research. 1. The abdomen and hip gradient turned out as the most influential factor on the appearance and the function of Divided Skirt. The pattern of which the abdomen and hip gradient was designated as vertical zero degree, showed an excellent appearance and in case of function, the pattern of which thw angle of the abdomen and hip gradient of human body type was applied to itself without a particular designation turned out excellent. 2. In case of crotch depth, the pattern which had crotch depth+2㎝, had a better appearance but influced nothing on function. 3. The factor of crotch width didn\`t have any influence on the appearance and function of Divided Skirt. 4. Referring to the results of the above, the Divided Skirt pattern of which the appearance and the function turned excellent, had the angle of abdomen gradient 4 degrees, the angle abdomen gradient 4 degrees, the angle of hip gradient/2+2.5 degrees, crotch depth+2㎝ and crotch width following human body type. In case of Divied Skirt worn when going out, the pattern which had the angle of abdomen and hip gradient vertical zero degree, crotch depth+2㎝ and crotch width following human body type, turned out suitable. Also, the suitable pattern of Divided Skirt for working had the abdomen and hip gradient following human body type, crotch depth+2㎝ and covering girth diameter/2±1㎝.

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