• 한국의류산업학회지
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• 제13권4호
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• pp.600-613
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• 2011

The purpose of this study is to provide Torso pattern for Korean middle-aged women using 3D human body scan data. 155 women in their 40's or 50's were measured by Martin's anthropometry. Merging the data of 914 middle aged women provided by Korean agency for technology and standards, total of 1,069 subjects' data were analyzed. For data analysis, ANOVA, factor analysis and cluster analysis were done using SPSS PC+. And representative subject of each cluster was selected and they participated in 3D scanning and Torso pattern suggested for middle-aged women Torso pattern which investing the amount of ease according to each group for diffuse front interscye 30%, armscye circumference 30%, back interscye 40% using 3D human body scan data. The results of this study are as follows. Firstly, as a result of the factor analysis, the first factor was 'obesity index of body', The second factor was 'verticality size of body', The third factor was 'verticality length of upper bodice', The fourth factor was 'drop value to represent silhouette', and the fifth factor was 'physique of upper bodice'. And, middle-aged women type were classified 3 types according to the cluster analysis. Type 1(Y-type) was the long upper Torso with wide shoulder. Type 2(H-type) was flat-body type with comparatively thin upper bodice and thin lower bodice. And type 3(A-type) was the obese type with comparatively thin upper bodice and fat lower bodice. Secondly, using CAD program, point filtering was performed and approximated surface model was made. It used that generated surface smoothing corrected for abnormally extruded points and scattered points based on the curvature information. And 3D surfaces were flatted onto the plane by the internal tools of CAD program. Difference ratios of outline length and area between 3D curves and 2D plane were 0.42% and 0.54%, respectively. Third, wearing test by the sensory evaluation showed that distinct difference almost every category. The movement functionality test shows that, in all the tests which reveal significant differences, especially, 'comparison pattern A' experienced inconvenience to neck width and neck depth.

• Journal of Microbiology
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• 제39권1호
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• pp.67-73
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• 2001

A validation study was conducted to evaluate the efficacy and mechanism of the cryo-precipitation, monoclonal anti-FVIIIc antibody (mAb) chromatography, Q-Sepharose chromatography, and lyophilization steps involved in the manufacture of high purity factor VIII (GreenMono) from human plasma, in the removal and/or inactivation of hepatitis A virus (HAV). Samples from the relevant stages of the production process were spiked with HAV and subjected to scale-down processes mimicking the manufacture of the high purity factor VIII concentrate. Samples were collected at each step and immediately titrated using a 50% tissue culture infectious dose (TCID$\_$50/) and then the virus reduction factors were evaluated. HAV was effectively partitioned from factor VⅢ during cryo-precipitation with the log reduction factor of 3.2. The mAb chromatography was the most effective step far removal of HAV with the log reduction factor of $\geq$4.3. HAV infectivity was not detected in the fraction of factor VⅢ, while most of HAV infectivity was recovered in the fractions of flow through and wash during mAb chromatography. Q-Sepharose chromatography showed the lowest efficacy for partitioning HAV with the log reduction factor of 0.7. Lyophilization was an effective step in inactivating HAV with the log reduction factor of 2.3. The cumulative lag reduction factor, $\geq$10.5, achieved for tile entire manufacturing process was several magnitudes greater than the potential HAV load of current plasma pools.

• 한국생활과학회지
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• 제17권2호
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• pp.305-313
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• 2008

This subject investigated visual evaluation of preference and fitness level of set-in sleeve in sleeve types(form)and studied suitable sleeve type at silhouette and targeted female students in twenties. The results of study were as follows: 1. Visual evaluation factors in set-in sleeve of sleeve types were selected 6 factors; the 1st factor is decorativeness, the 2nd factor is attractiveness, the 3rd factor was activeness, the 4th factor was feminine, the 5th factor was charming and 6th factor was a figural element. Decorativeness and attractiveness factors in visual evaluation of sleeve types were the most important level. 2. The visual evaluation differences of sleeve types in set-in sleeve were as follows; in the 1st factor, S and P2 were the most decorative sleeve type. in the 2nd factor, S, P2 and P3 are the most attractive sleeve type. in the 3rd factor, B and P3 were the most active sleeve type. in the 4th factor, L was the most feminine sleeve type. in the 5th factor, P1, L and P3 were charming sleeve type. in the 6th factor, P3 was evaluated that it shows narrowened shoulder sleeve types. 3. The analysis result of preference and wearing level in each sleeve types were as follows. 20's female university students like to wear S, P1, P2 and P3 sleeve types and the most favorite sleeve types are S, P2 and P3. 4. The analysis result of silhouette set-in sleeve in sleeve types; S, B and P2 in H-type silhouette, P2, S and P1 in A-type silhouette, B and P3 in O-type silhouette, L and P3 in X-types silhouette were show the most suitable sleeve types.

• Archives of Pharmacal Research
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• 제17권5호
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• pp.381-382
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• 1994

Administration route dependency on the distribution of PEGylated recombinant human turor necrosis factor binding protein (rhTNFbp-PEG20K dimer) was observed following a subcutaneous (sc) and an intravenous (iv) administrationin rats. ehTNFbp-PEG20K dimer is composed of two rhTNGbp molecules (molecular weight 18, 278 daltons each) joined by polyethylene glycol 2000(PEG30K). The steady state distribution volume of rhTNFbp-PEG20K was 55 m/kg and 359 ml/kg following the i.v. and s.c. administrations, respectively. These results suggest that the distribution of ehTNFbp-PEG20K is limited within the cpillary space after i.v. administration, while rhTNFbp-PEG20K can distribute into a space (35.9% of body weight) which is between extracellylar space and total body water. A lymphatic absorption may paly a role in the distribution of rhTNFbp-PEF20K dimer following the sc administration. The present study suggests that the administration route of a lartge protein molecule should be determined depedning upon target sites.

• 한국항공운항학회지
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• 제22권4호
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• pp.99-109
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• 2014

Airline and medical industry in Korea have rapidly grown since 21st century. However, air ambulance service using an aircraft has not as popular as in Japan, Europe or United States. Central government has decided to start emergency helicopter service since 2011 to transport emergency patients transported in the past by fire fighter helicopter. Unfortunately, 32 OECD countries out of 33 have operated emergency aircraft system except Korea. There are more than 25 emergency helicopters in Japan, which can operate within five minutes. Such system could save a lot of social direct or in-direct cost by saving valuable lives of Japan citizens. This paper has tried to research the perception of overseas Russian medical tourists on using Air ambulance for their medical tourism to Korea. Researching air ambulance, this paper expects to find ways to enhance both medical tourism industry and airline, business jet industry. According to research results, it was proven that tangibility of medical tourism service has a positive effect on the human factor of air ambulance. The human factor has also a significant impact on the passenger comfortableness of air ambulance. Such comfortableness increases the overall satisfaction of medical tourism.

• International Journal of Oral Biology
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• 제46권3호
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• pp.99-104
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• 2021

Associations between periodontal infection and cardiovascular disease have been documented. Porphyromonas gingivalis is a well-established periodontal pathogen, and tissue factor (TF) is a key initiator of the coagulation cascade. In this context, P. gingivalis has been reported to enhance TF expression in human endothelial cells. The present study investigated the underlying mechanisms of TF induction by P. gingivalis in human umbilical vein endothelial cells. P. gingivalis increased TF expression in a dose- and time-dependent manner. Not only live bacteria but also glutaraldehyde-fixed bacteria increased TF expression to the same extent. However, sonicates of P. gingivalis did not induce TF expression. Cytochalasin D and SMIFH2, which are inhibitors of actin polymerization and actin nucleation, respectively, inhibited the TF expression induced by P. gingivalis. Finally, TF production was decreased or increased in the presence of various signaling inhibitors, including mitogen-activated protein kinases. These results suggest that P. gingivalis induces endothelial TF expression by a bacterial internalization-dependent mechanism and through diverse signal transduction mechanisms.

• The Journal of Asian Finance, Economics and Business
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• 제8권7호
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• pp.43-54
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• 2021

Human capital and innovation capacities are essential elements and one of the sustainable approaches to driving economic growth. However, there is debate among scholars concerning these two factors in fostering economic growth. This study investigates the relationships between human capital and innovation capacity and economic growth in selected ASEAN countries, namely, Malaysia, Thailand, and Indonesia. Economists widely discussed the interrelation of human capital and innovation. A large body of literature stated that human capital is an essential factor and engine of economic growth. Innovation has become key in transforming the economic development of developing countries. We analyze human capital (HC) and innovation capacity (INC) using static panel data analysis. The data analysis shows that the fixed-effect model is the best model in this study. Further, human capital (HC) has a significant positive relationship with economic growth. Meanwhile, innovation capacity has no significant relationship with economic growth. We also found that Malaysia's coefficient of human capital and innovation capacity is higher and more efficient than in Thailand and Indonesia. In conclusion, human capital and innovation capacity are crucial elements for measuring economic growth. Skilled human capital contributes significantly to the economic growth and economic development of a nation.

• 디지털융복합연구
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• 제15권7호
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• pp.415-424
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• 2017

본 연구는 공중의 체세포복제기술에 대한 위험특성, 위험심각성, 위험인식 및 위험수용의 관계를 살펴보기 위하여 서울에 거주하는 한국인 300명을 대상으로 IBM SPSS 21 프로그램과 IBM AMOS 21 프로그램을 활용하여 탐색적 요인분석과 확인적 요인분석, 상관관계 분석, 구조모형분석을 수행하였다. 주요결과를 요약 제시하면 다음과 같다. 첫째, 공중의 체세포복제기술에 대한 위험특성은 위험심각성에 통계적으로 유의한 정적 영향을 미치는 것으로 나타났다. 둘째, 공중의 체세포복제기술에 대한 위험특성은 위험인식에 통계적으로 유의한 정적 영향을 미치는 것으로 나타났다. 셋째, 공중의 체세포복제기술에 대한 위험심각성은 위험인식에 통계적으로 유의한 정적 영향을 미치는 것으로 나타났다. 넷째, 공중의 체세포복제기술에 대한 위험특성은 위험수용에 통계적으로 유의한 부적 영향을 미치는 것으로 나타났다. 다섯째, 공중의 체세포복제기술에 대한 위험심각성은 위험수용에 통계적으로 유의한 영향을 미치지 못하였다. 여섯째, 공중의 체세포복제기술에 대한 위험인식은 위험수용에 통계적으로 유의한 영향을 미치지 못하였다.

• Safety and Health at Work
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• 제8권1호
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• pp.11-18
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• 2017

The purpose of this review is to name and describe the important factors of musculoskeletal strain originating from pushing and pulling tasks such as cart handling that are commonly found in industrial contexts. A literature database search was performed using the research platform Web of Science. For a study to be included in this review differences in measured or calculated strain had to be investigated with regard to: (1) cart weight/ load; (2) handle position and design; (3) exerted forces; (4) handling task (push and pull); or (5) task experience. Thirteen studies met the inclusion criteria and proved to be of adequate methodological quality by the standards of the Alberta Heritage Foundation for Medical Research. External load or cart weight proved to be the most influential factor of strain. The ideal handle positions ranged from hip to shoulder height and were dependent on the strain factor that was focused on as well as the handling task. Furthermore, task experience and subsequently handling technique were also key to reducing strain. Workplace settings that regularly involve pushing and pulling should be checked for potential improvements with regards to lower weight of the loaded handling device, handle design, and good practice guidelines to further reduce musculoskeletal disease prevalence.

• 한국산학기술학회논문지
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• 제14권5호
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• pp.2168-2177
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• 2013

본 연구는 대졸자 직업이동 경로조사 (GOMS: Graduates Occupational Mobility Survey) 2010년도를 활용하여 대졸자 4051명의 취업결정요인의 주관적 인지가 직무만족에 미치는 영향을 분석하였다. 취업결정요인의 주관적 인지는 학력요인, 자격/전공요인, 인성/인맥요인 등으로 설정하였고, 직무만족을 내재적 만족과 외재적 만족 등으로 구성하였다. 연구결과는 다음과 같다. 첫째, 대졸자의 성별, 학교유형, 학교소재지, 전공 등에 따라 취업결정요인의 주관적 인지와 직무만족에 차이가 있었다. 둘째, 비수도권 소재 학교, 교육계열, 학력요인, 자격/전공요인, 인성/인맥요인 등이 내재적 만족에 정(+)의 영향을 끼치는 것을 알 수 있었다. 셋째, 2~3년제 대학, 비수도권 소재 학교, 사회계열, 교육계열, 공학계열, 자연계열, 의약계열, 학력요인, 자격/전공요인, 인성/인맥요인이 외재적 만족에 정(+)의 영향을 끼치는 것을 알 수 있었다. 본 연구는 대학생의 취업결정요인의 주관적 인지에 대한 세분화된 분석 자료를 제공하고 직무만족에 대한 새로운 검증에 의미가 있다.