• 제목/요약/키워드: Human Enhancement

검색결과 753건 처리시간 0.026초

Evaluation of Cell Based Anti-oxidation Assay of Functional Components Derived from Domestic Major Potato Varieties

  • Jung Hwan Nam;Su Young Hong;Su Jeong Kim;Hwang Bae Sohn;Yul Ho Kim;Kyung Tea Lee;Soo jin Park;Jae Kwon Lee
    • 한국자원식물학회:학술대회논문집
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    • 한국자원식물학회 2020년도 춘계학술대회
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    • pp.75-75
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    • 2020
  • Potatoes were first introduced outside the Andes region four centuries ago, and have become an integral part of much of the world's food. Potatoes were first introduced into Europe in the 16th century and Korea in the early 19th century. Potatoes have a short growing season, high production per unit area, relatively strong environmental adaptability, and are cultivated in more than 130 countries around the world. It is the world's fourth-largest crop, following rice, wheat, bean and maize. In the nutritional aspects, potatoes contain abundant vitamins and minerals, as well as an assortment of phytochemicals such as carotenoids and natural phenols. Due to the high content of potato functional compounds, it has known that potatoes are effective in the prevention of various human diseases. In particular, the potato contains a large amount of polar compounds, including the saponin in the polar compounds, and the physiological activity of the saponins, such as immunity enhancement, antioxidant and anti-inflammatory is known. In this study, the antioxidative activity of polar compounds from five potatoes was examined by cell based anti-oxidation assay. The smallest amount of ROS(Reactive oxygen species) was generated when the compound was derived from 'Haryung' and 'hongyoung' and strong SOD(Superoxide dismutase) activity was observed in 'Sumi' and 'Jayoung'. The results of this study reveal the antioxidative effect of polar compounds extracted from various kind of potatoes, which will enable the acquisition of new bioactive candidates and the establishment of new profit generation models for farmers

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Study on OCR Enhancement of Homomorphic Filtering with Adaptive Gamma Value

  • Heeyeon Jo;Jeongwoo Lee;Hongrae Lee
    • 한국컴퓨터정보학회논문지
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    • 제29권2호
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    • pp.101-108
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    • 2024
  • AI-OCR은 광학 문자 인식(OCR) 기술과 Artificial intelligence(AI)의 결합으로 사람의 인식이 필요하던 OCR의 단점을 보완하는 기술 향상을 이뤄내고 있다. AI-OCR의 성능을 높이기 위해서는 다양한 학습데이터의 훈련이 필요하다. 하지만 이미지 색상이 비슷한 밝기를 가진 경우에는 인식률이 떨어지기 때문에, Homomorphic filtering(HF)을 이용한 전처리 과정으로 색상 차이를 분명하게 하여 텍스트 인식률을 높이게 된다. HF은 감마값을 이용해 이미지의 고주파와 저주파를 각각 조절한다는 점에서 텍스트 추출에 적합하지만 감마값의 조절이 수동적으로 이뤄지는 단점이 존재한다. 본 연구는 시험적 과정을 거쳐 이미지의 대비, 밝기 및 엔트로피를 근거하는 감마의 임계값 범위를 제안한다. 제안된 감마값 범위를 적용한 HF의 실험 결과는 효율적인 AI-OCR의 높은 등장 가능성을 시사한다.

The Color-Developing Methods for Cultivated Meat and Meat Analogues: A Mini-Review

  • Ermie Jr Mariano;Da Young Lee;Seung Hyeon Yun;Juhyun Lee;Yeongwoo Choi;Jinmo Park;Dahee Han;Jin Soo Kim;Sun Jin Hur
    • 한국축산식품학회지
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    • 제44권2호
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    • pp.356-371
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    • 2024
  • Novel meat-inspired products, such as cell-cultivated meat and meat analogues, embrace environmental sustainability, food safety and security, animal welfare, and human health, but consumers are still hesitant to accept these products. The appearance of food is often the most persuasive determinant of purchasing decisions for food. Producing cultivated meat and meat analogues with similar characteristics to conventional meat could lead to increased acceptability, marketability, and profitability. Color is one of the sensorial characteristics that can be improved using color-inducing methods and colorants. Synthetic colorants are cheap and stable, but natural pigments are regarded as safer components for novel food production. The complexity of identifying specific colorants to imitate both raw and cooked meat color lies in the differences in ingredients and methods used to produce meat alternatives. Research devoted to improving the sensorial characteristics of meat analogues has noted various color-inducing methods (e.g., ohmic cooking and pasteurization) and additives (e.g., lactoferrin, laccase, xylose, and pectin). Additionally, considerations toward other meat components, such as fat, can aid in mimicking conventional meat appearance. For instance, the use of plant-based fat replacers and scaffolds can produce a marked sensory enhancement without compromising the sustainability of alternative meats. Moving forward, consumer-relevant sensorial characteristics, such as taste and texture, should be prioritized alongside improving the coloration of meat alternatives.

복합화력발전소 내 수소연료 저장설비의 안전관리 체계 구축을 위한 Bow-tie 기법을 활용한 반정량적 위험성 평가 (Semi-quantitative Risk Assessment using Bow-tie Method for the Establishment of Safety Management System of Hydrogen Fuel Storage Facility in a Combined Cycle Power Plant)

  • 박희경;정시우;최유정;이민철
    • 한국안전학회지
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    • 제39권2호
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    • pp.75-86
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    • 2024
  • Hydrogen has been selected as one of the key technologies for reducing CO2 emissions to achieve carbon neutrality by 2050. However, hydrogen safety issues should be fully guaranteed before the commercial and widespread utilization of hydrogen. Here, a bow-tie risk assessment is conducted for the hydrogen fuel supply system in a gas turbine power plant, which can be a mass consumption application of hydrogen. The bow-tie program is utilized for a qualitative risk assessment, allowing the analysis of the causes and consequences according to the stages of accidents. This study proposed an advanced bow-tie method, which includes the barrier criticality matrix and visualized maps of quantitative risk reduction. It is based on evaluating the importance of numerous barriers for the extent of their impact. In addition, it emphasizes the prioritization and concentrated management of high-importance barriers. The radar chart of a bow tie allows the visual comparison of risk levels before/after the application of barriers (safety measures). The risk reduction methods are semi-quantitatively analyzed utilizing the criticality matrix and radar chart, and risk factors from multiple aspects are derived. For establishing a secure hydrogen fuel storage system, the improvements suggested by the bow-tie risk assessment results, such as 'Ergonomic equipment design to prevent human error' and 'Emergency shutdown system,' will enhance the safety level. It attempts to contribute to the development and enhancement of an efficient safety management system by suggesting a method of calculating the importance of barriers based on the bow-tie risk assessment.

A Novel System with EMG-controlled FES Enhanced Gait Function and Energy Expenditure for Older Adults

  • Jang-hoon Shin;Hye-Kang Park;Joonyoung Jung;Dong-Woo Lee;Hyung cheol Shin;Hwang-Jae Lee;Wan-hee Lee
    • Physical Therapy Rehabilitation Science
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    • 제13권2호
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    • pp.152-162
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    • 2024
  • Objective: This study was conducted to analyze the effect of wearable Electromyography-controlled functional electrical stimulation (EMG-controlled FES) System on Gait Function and cardiopulmonary metabolic efficiency during walking in older adults. Design: Cross-section study Methods: Total 22 older adult participants suitable to selection criteria of this study participated in this study. The EMG-controlled FES System, which functions as a wearable physical activity assist FES system was used. All participations performed randomly assigned two conditions (Non-FES assist [NFA], FES assist [FA]) of walking. In all conditions, spatio-temporal parameters and kinematics and kinetics parameters during walking was collected via 3D motion capture system and 6 minutes walking test (6MWT) and metabolic cost during walking and stairs climbing was collected via a portable metabolic device (COSMED K5, COSMED Srl, Roma, Italy). Results: In Spatio-temporal parameters aspects, The EMG-controlled FES system significantly improved gait functions measurements of older adults with sarcopenia at walking in comparison to the NFA condition (P<0.05). Hip, knee and ankle joint range of motion increased at walking in FA condition compared to the NFA condition (P<0.05). In the FA condition, moment and ground reaction force was changed like normal gait during walking of older adults in comparison to the NFA condition (P<0.05). The EMG-controlled FES system significantly reduced net cardiopulmonary metabolic energy cost, net energy expenditure measurement at stairs climbing (P<0.05). Conclusions: This study demonstrated that EMG-controlled FES is a potentially useful gait-assist system for improving gait function by making joint range of motion and moment properly.

Enabling Effective Implementation of Occupational Safety and Health Interventions

  • Gaia Vitrano;Davide Urso;Guido J.L. Micheli;Armando Guglielmi;Diego De Merich;Mauro Pellicci
    • Safety and Health at Work
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    • 제15권2호
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    • pp.213-219
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    • 2024
  • Background: The design, implementation, and evaluation are three important stages of occupational safety and health (OSH) interventions. Historically, there has been a tendency to prioritize implementation, often neglecting detailed design and rigorous outcome evaluation. Currently, much has changed, and contemporary approaches recognize the interdependence of these stages, considering them integral to the success of any intervention. This work presents a comprehensive procedure for implementing interventions, not only to ensure short-term effectiveness but also their long-term sustainability through continuous monitoring. The focus is on a national OSH project introducing a near-miss management system (NMS) in Italy. Methods: Initial meetings were convened among project partners, complemented by interviews with diverse stakeholders, to plan implementation steps and test the NMS. Tailored questionnaires were designed for diverse stakeholder groups - initial promoters, company managers and employers, and employees - facilitating targeted implementation, and three case studies were started in Italian regions to assess the structured implementation, involving intervention promoters and collaborating companies. Results: The primary outcome is the development of practical tools, specifically three questionnaires, which are considered valuable for establishing an effective human-centered implementation strategy, meticulously designed to facilitate ongoing monitoring of processes and continual enhancement of instruments intended for NMS integration within companies. Conclusions: This work lays the foundation for successful NMS implementation in Italy and, although the outlined procedure had specific objectives, it also provides valuable insights applicable in enhancing the effectiveness and sustainability of interventions across diverse contexts. It underscores the importance of comprehensive planning, stakeholder engagement, and continuous evaluation in achieving lasting OSH interventions.

Combination of metal artifact reduction and sharpening filter application for horizontal root fracture diagnosis in teeth adjacent to a zirconia implant

  • Debora Costa Ruiz;Larissa de Oliveira Reis;Rocharles Cavalcante Fontenele;Murilo Miranda-Viana;Amanda Farias-Gomes;Deborah Queiroz Freitas
    • Imaging Science in Dentistry
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    • 제54권3호
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    • pp.289-295
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    • 2024
  • Purpose: This study examined the influence of metal artifact reduction (MAR), the application of sharpening filters, and their combination on the diagnosis of horizontal root fracture (HRF) in teeth adjacent to a zirconia implant on cone-beam computed tomography (CBCT) examinations. Materials and Methods: Nineteen single-rooted teeth (9 with HRF and 10 without) were individually positioned in the right central incisor socket of a dry human maxilla. A zirconia implant was placed adjacent to each tooth. Imaging was performed using an OP300 Maxio CBCT (Instrumentarium, Tuusula, Finland) unit with the following settings: a current of 8 mA, both MAR modes(enabled and disabled), a 5×5 cm field of view, a voxel size of 0.085 mm, and a peak kilovoltage of 90 kVp. Four oral and maxillofacial radiologists independently evaluated the CBCT scans under both MAR conditions and across 3 levels of sharpening filter application (none, Sharpen 1×, and Sharpen 2×). Diagnostic metrics were calculated and compared using 2-way analysis of variance (α=5%). The weighted kappa test was used to assess intra- and inter-examiner reliability in the diagnosis of HRF. Results: MAR tool activation, sharpening filter use, and their combination did not significantly impact the area under the receiver operating characteristic curve, sensitivity, or specificity of HRF diagnosis (P>0.05). Intra- and inter-examiner agreement ranged from fair to substantial. Conclusion: The diagnosis of HRF in a tooth adjacent to a zirconia implant is not affected by the activation of MAR, the application of a sharpening filter, or the combination of these tools.

근로가치관이 플랫폼 노동자의 직무 태도에 미치는 영향에 관한 연구 (The Effects of Work Values on Job Attitude of Platform Workers)

  • 류성열;박상철;김경규
    • 지식경영연구
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    • 제25권3호
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    • pp.23-45
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    • 2024
  • 플랫폼 기업의 알고리즘 경영이 강화되고, 법적으로 플랫폼 노동자의 '근로자성'이 인정받는 영역이 확대되고 있는 상황은, 플랫폼 기업이 내부 인력 자원으로서의 플랫폼 노동자의 직무 태도에 대한 이해를 확대시켜야 할 시기라는 것을 의미한다. 본 연구에서는 알고리즘 경영이 플랫폼 노동자의 직무 태도 전반에 대한 인식의 변화를 유도하고 있는 상황에서, 플랫폼 노동자의 근로가치관에 따른 직무 태도의 차이를 밝혀보고자 한다. 본 연구는 플랫폼 노동자의 근로 가치관에 따른 직무 태도 인식에 관한 차이를 알아보고자 하였다. 이를 위해 알고리즘 경영을 도입한 배달 플랫폼을 이용하는 라이더 177명에 대한 설문 조사 자료를 활용하여 다변량 분산분석을 실시하였다. 연구 결과, 근로가치관(직무 관심)을 중시하는 플랫폼 노동자일수록 보상공정성과 자율성이 높은 것으로 나타났다. 또한, 근로가치관(경제적 보상 관심)을 중시하는 플랫폼 노동자일수록 업무 과부하, 보상 공정성, 직무 소진, 이직 의도 등이 높은 것으로 나타났다.

베트남의 해양기름유출 현황과 국가대응역량 증강 방안 - 통계자료와 유출유 방제시스템에 대한 베트남과 한국 간의 비교를 통하여 - (The Present State of Marine Oil Spills and the Enhancement Plans of National Oil Spill Response Capability in Vietnam - Through the Comparison of Statistics and OSR System between Vietnam and Republic of Korea -)

  • 판반흥;김광수
    • 해양환경안전학회지
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    • 제23권6호
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    • pp.690-698
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    • 2017
  • 베트남은 3,444 km가 넘는 해안선, 수천 개의 섬 그리고 길이 4260 km 이상인 2,360개의 강과 수로가 있는 해양국이다. 선박에 의한 유류수송의 빈도와 수송량이 증가하면서 기름유출사고의 가능성이 과거 어느 때보다 높아지고 있다. 해상에서의 연료유 및 화물유의 유출은 해양생태계, 연안자원 및 인간건강은 물론 사회 경제에 대하여 광범위하고 장기적인 영향을 미친다. 본 연구는 20년 동안의 기름유출사고 건수와 유출량과 같은 베트남의 해양기름유출 현황 그리고 기름유출대응(OSR)에 대한 국가체제 등과 같은 국가대응체계에 관한 전반을 보여줄 뿐만 아니라, 특히 베트남과 한국 사이의 국가기름유출대응체제를 비교함으로써 기름유출사고에 대응하여 베트남의 국가역량을 강화하기 위한 권고안을 제시하고자 한다. 그 결과, 베트남의 해양기름유출사고 건수와 유출량은 한국의 하락 추세와는 대조적으로 상승 추세를 보였다. 이는 베트남의 연안 해역에서 실제적 기름유출 가능성이 높다는 것을 의미한다. 따라서 베트남의 국가기름유출대응역량을 강화하기 위한 3가지 주요 권고안을 다음과 같이 제안한다. 즉 (1) OPRC협약의 수락 이행 그리고 유류오염으로 인한 피해 및 손실을 보상하는 국가기금의 조성과 같은 기름유출사고에 대비하고 대응하기 위한 법률제도를 포함한 국가기름유출대응 시스템을 강화하기 위한 방안의 개발; (2) 일관된 보고, 경보 및 모니터링 시스템의 강화; (3) 표준 교육과정 내용으로 구성된 교육 및 훈련 프로그램의 개발을 제안하고자 한다.

Naringenin에 의한 인체혈구암세포의 apoptosis 유발에 미치는 pro-apoptotic Bcl-2의 영향 (Effect of Proapoptotic Bcl-2 on Naringenin-induced Apoptosis in Human Leukemia U937 Cells)

  • 박철;;최태현;홍수현;최영현
    • 생명과학회지
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    • 제23권9호
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    • pp.1118-1125
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    • 2013
  • 감귤류에 많이 함유되어 있는 naringenin은 항암화학요법제로서 중요한 가능성을 가지고 있으나 항암활성에 대한 분자생물학적 기전에 대해서는 명확히 밝혀져 있지 않다. 본 연구에서는 인체 혈구암세포인 U937 세포에서 naringenin이 유발하는 항암효과 및 항암기전을 조사하였다. Naringenin 처리에 의한 U937 세포의 증식억제는 apoptosis 유발과 연관성이 있었으며, 이러한 현상은 caspases 활성화와 밀접한 관련이 있었다. 그러나 pan-caspase inhibitor인 z-VAD-fmk의 선처리에 의하여 U937 세포에서 naringenin이 유발하는 apoptosis가 억제되는 것으로 나타났으므로 caspases가 apoptosis 유발의 중요한 조절자라는 것을 알 수 있었다. 또한 U937 세포에 naringenin을 처리하였을 경우 pro-apoptotic Bcl-2 및 anti-apoptotic Bax의 발현에는 아무런 변화가 나타나지는 않았지만 Bcl-2가 과발현된 U937/Bcl-2 세포에서 naringenin에 의한 apoptosis가 억제되었다. 하지만 small-molecule Bcl-2 inhibitor인 HA14-1 및 naringenin을 같이 처리하였을 경우에는 XIAP 발현감소, Bid 단편화 및 caspase-3 활성화를 통하여 다시 apoptosis가 유발되었다. 따라서 HA14-1 및 naringenin에 의한 apoptosis 상승효과는 death receptor-mediated apoptosis pathway를 경유한다는 것을 제시하는 결과이다.