• Journal of the Korea Institute of Building Construction
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• v.11 no.1
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• pp.29-34
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• 2011

Since the study of building performance design was first undertaken by Building Research Station in 1930s, the results of such study has been reported from many parts of the world, building construction codes and standards have been revised based on performance in advanced nations as well in Korea, and various performance certification systems are in operation. The purpose of this study is to build a database of performance certification systems to investigate the co-relationship of various test methods related to the same test items. As test methods for case study, we selected test methods involving collision of the human body. Through analysis of Critical fall height test of EN 1177 and Head Model test of JIS A 6519 about 8 species of floor test-bodies, it was found that there are limits of application in terms of the depth and strength of cushion. Furthermore, although the measured physical parameters are the same, when the co-relationship between test methods is uncertain, the various physical parameters may not be compatible with the results.

• Biomolecules & Therapeutics
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• v.28 no.3
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• pp.250-258
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• 2020

Emphysema, a major component of chronic obstructive pulmonary disease (COPD), is a leading cause of human death worldwide. The progressive deterioration of lung function that occurs in the disease is caused by chronic inflammation of the airway and destruction of the lung parenchyma. Despite the main impact of inflammation on the pathogenesis of emphysema, current therapeutic regimens mainly offer symptomatic relief and preservation of lung function with little therapeutic impact. In the present study, we aimed to discover novel therapeutics that suppress the pathogenesis of emphysema. Here, we show that LJ-2698, a novel and highly selective antagonist of the adenosine A₃ receptor, a G protein-coupled receptor involved in various inflammatory diseases, significantly reversed the elastase-induced destructive changes in murine lungs. We found that LJ-2698 significantly prevented elastase-induced airspace enlargement, resulting in restoration of pulmonary function without causing any obvious changes in body weight in mice. LJ-2698 was found to inhibit matrix metalloproteinase activity and pulmonary cell apoptosis in the murine lung. LJ-2698 treatment induced increases in anti-inflammatory cytokines in macrophages at doses that displayed no significant cytotoxicity in normal cell lines derived from various organs. Treatment with LJ-2698 significantly increased the number of anti-inflammatory M2 macrophages in the lungs. These results implicate the adenosine A₃ receptor in the pathogenesis of emphysema. Our findings also demonstrate the potential of LJ-2698 as a novel therapeutic/preventive agent in suppressing disease development with limited toxicity.

• Journal of environmental and Sanitary engineering
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• v.8 no.2
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• pp.25-48
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• 1993

International concern over the environmental pollution is ever increasing, and diversified countermeasures must be devised in Korea also. Global trend, damages, problems and countermeasures with respect to issues mentioned in the Rio Declaration, such as prevention of ozone layer destruction, reduction of migratory atmospheric pollution between neighboring countries, and prevention of global greenhouse effect, were discussed in this report. Conclusion of the report is summarized as follows : A. Measurement, Planning and Monitoring (1) Development and implementation of a global network for measurement and monitoring from the global aspects such factors as related to acid rain(Pioneer substances, pH, sulfate, nitrate), effect of global temperature(Air temperature, $CO_2$, $CH_4$, CFC, $N_2O$) and destruction of ozone layer($CFC_S$). (2) Establishment of network system via satellite monitoring movement of regional air mass, damage on the ozone layer and ground temperature distribution. B. Elucidation of Present State (1) Improvement and development of devices for carbon circulation capable of accurately forecasting input and output of carbon. (2) Developmental research on chemical reactions of greenhouse gas in the air. (3) Improvement and development of global circulation model(GCM) C. Impact Assessment Impact assessment on ecosystem, human body, agriculture, floodgate, land use, coastal ecology, industries, etc. D. Preventive Measures and Technology Development (1) Development and consumption of new energy (2) Development of new technology for removal of pioneer substances (3) Development of substitute matter for $CFC_S$ (4) Improvement of agriculture and forestry means to prevent the destruction of ozone layer and the greenhouse effect of the globe (5) Improvement of housing to prevent the destruction of ozone layer and the greenhouse effect of the globe (6) Development of new technology for probing underground water (7) Preservation of forest (8) Biomass 5. Policy Development (1) Development of strategy model (2) Development of long term forecast model (3) Development of penalty charge effect and expense evaluation methods (4) Feasibility study on regulations By establishing the above mentioned measures for environmentally sound and sustainable development to establish the right to live for humankind and to preserve the one and only earth.

• Journal of Environmental Impact Assessment
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• v.20 no.5
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• pp.641-649
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• 2011

The ground vibration has effect on the human body and the nearby structure. However, it was very difficult to estimate the damage of structure caused by the vibration. Especially, ground vibration must be estimated on the bottom of structure because it was made up of several mediums. In this study, it was considered about the shock vibration on medium characteristics as calculating the peak particle velocity and analysing the vibration waveform. The results are as follows : Firstly, the correlation coefficient of PPV(Peak Particle Velocity) and SD(Scaled Distance) was very high at the vertical component, which was represented to 0.991 in general ground medium and each 0.989, 0.961, 0.925 in concrete medium. And also, the vibration waveform at the vertical component was very good in all mediums. Secondly, the vibration waveform at the longitudinal component was represented to a great amplitude and phase difference in all mediums. It was considered that the vibration waveform occurred the damping when particle velocity by shock vibration was propagated through other medium. Thirdly, the vibration waveform in concrete medium was represented to variation of amplitude in the order of RC medium, NC=H medium, NC=S medium at the vertical component. It was considered that the particle velocity propagated fast when a medium have a big strength and density.

• Horticultural Science & Technology
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• v.32 no.5
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• pp.710-720
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• 2014

Movements of the upper and lower limb muscles during five common gardening tasks were analyzed by using electromyography (EMG). Twenty adults aged in their twenties (mean age, $24.8{\pm}2.4$ years) were recruited. On two separate occasions, subjects visited a garden plot to perform digging, raking, troweling, weeding, and hoeing; all tasks were performed three times with 20 s intervals for each trial. To measure muscle activation during the five gardening tasks, surface EMG was used. Bipolar surface EMG electrodes were attached to eight upper limb muscles (bilateral anterior deltoid, biceps brachialis, brachioradialis, and flexor carpi ulnaris) or eight lower limb muscles (bilateral vastus lateralis, vastus medialis, biceps femoris, and gastrocnemius) on both sides of the body, for a total of 16 muscles. During the five tasks, photographs were taken of movement phases using a digital video camera. The right flexor carpi ulnaris and brachioradialis showed higher activation than the other upper and lower limb muscles measured during the tasks. All 16 upper and lower limb muscles were actively used only during digging. According to movement analysis of each activity, digging was classified into four movement phases, whereas raking, troweling, weeding, and hoeing each were divided into three movement phases. In each activity, there were high-impact phases in terms of muscle activation; the flexor carpi ulnaris and brachioradialis were identified as major muscles in each impact phase. This analysis may be used to generate biomechanical profiles of gardening tasks for practitioners when designing efficient gardening interventions for physical health or rehabilitation.

• Tuberculosis and Respiratory Diseases
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• v.81 no.2
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• pp.116-122
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• 2018

Background: Chronic obstructive pulmonary disease (COPD) is a serious chronic condition with a global impact. Symptoms of COPD include progressive dyspnea, breathlessness, cough, and sputum production, which have a considerable impact on the lives of patients. In addition to the human cost of living with COPD and the resulting death, COPD entails a huge economic burden on the Chinese population, with patients spending up to one-third of the average family income on COPD management in some regions is clinically beneficial to adopt preventable measures via prudent COPD care utilization, monetary costs, and hospitalizations. Methods: Toward this end, this study compared the relative effectiveness of six indices in predicting patient healthcare utilization, cost of care, and patient health outcome. The six assessment systems evaluated included the three multidimensional Body mass index, Obstruction, Dyspnea, Exercise capacity index, Dyspnea, Obstruction, Smoking, Exacerbation (DOSE) index, and COPD Assessment Test index, or the unidimensional measures that best predict the future of patient healthcare utilization, cost of care, and patient health outcome among Chinese COPD patients. Results: Multiple linear regression models were created for each healthcare utilization, cost, and outcome including a single COPD index and the same group of demographic variables for each of the outcomes. Conclusion: We conclude that the DOSE index facilitates the prediction of patient healthcare utilization, disease expenditure, and negative clinical outcomes. Our study indicates that the DOSE index has a potential role beyond clinical predictions.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.17 no.1
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• pp.130-137
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• 2018

In long freight trains, there is a brake time delay in the neighboring freight cars that causes damage and fractures of couplers, especially the knuckle of them. If there is a problem for couplers in the cars, this could cause a derailment and lead to damage of human life and property damage. In this study, maximum forces on the couplers are studied when a long freight car brakes, with brake delay time and coupler gap. We have made a dynamic model of 50 freight cars and couplers, applying contact between couplers and a characteristic curve for expressing force and displacement of buffers with SIMPACK, a multi-body dynamics program. We use EN 14531-2 from the British Standards Institution, a standard of freight car brakes for the verification of the dynamic model. We also use a simplified method to analyze the dynamic model of 50 freight cars. With changing coupler gap and brake delay time, we do comparative analysis with AAR M-201 from the Association of American Railroads, a standard of AAR couplers. From this result, we find that the standard on fatigue limit is satisfied, such that the brake delay time is within 0.06 second if the coupler gap of the AAR coupler is within 20 millimeters.

• Safety and Health at Work
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• v.11 no.4
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• pp.543-549
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• 2020

Background: The working conditions of bus drivers are difficult; they lead to occupational diseases and require careful study, particularly in Ukraine. The objective of the article is the description of occupational health risks of passenger bus drivers that lead to deteriorating health. Methods: The risk assessment was performed using a modified Risk Score method, which allowed determining the generalized level of danger to the driver's health. The hygienic hazards level was assessed as based on Stevenson's law, which was generalized later. Results: Based on the modification of the Risk Score method, it was possible to depart from expert assessments method of the risk level and calculate the general indicator based on the degree of dependence of the impact on the human body on its intensity, proposed by V. Minko. This allows objective determining of the impact of hygiene hazards on the health of the driver and to predict the occurrence of occupational diseases associated with the cardiovascular system, musculoskeletal system, and partial or complete disability due to the accumulation of emotional fatigue. The hazard assessment was carried out for three brands of passenger buses common in Ukraine, in which the driver is exposed to the dangers of fever, vibration, noise, harmful impurities in the bus cabin, and emotional load. Conclusion: The health of drivers in the cabins of passenger buses is most affected by hygiene hazards: fever, vibration, and emotional stress. The generalized level of risk is calculated by the modified method of Risk Score is 0.83; -0.99, -0.92 respectively.

• Journal of Oriental Neuropsychiatry
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• v.16 no.2
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• pp.125-133
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• 2005

Object : This paper is designed to inquire into the influence of eating habits on the emotion of modem people. Method : The methodology is used that searches for materials such as books and treatises on the relationship between eating habits and emotion. Result : Meat used for fast food comes from cows that are fed the feed containing growth hormone and antibiotic. Growth hormone extremely supplements fire or yang within the body while antibiotics undermines the process of yin, leading to an accumulation of damp-heat and inflammation of ministerial fire. Additives contained in instant foods also impinge on the process of yin, leading to poor digestion, damp-heat toxins and ministerial fire. Excessive consumption of meat results in incomplete combustion of fat and hinders the formation of essence. Subsequently, ministerial fire becomes hyperactive as a result of the lack of yin energy. Increased meat consumption in the human diet is coupled with unhealthy eating pattern in which people eat too much for dinner and too quickly. Eating too much disturbs digestion, making it slow and incomplete, leading to excess damp-heat conditions, insufficient amount of vital essence and eventually hyperactive ministerial fire. Milk is considered a catalyst of faster growth, making it suitable for calves. Milk intake rapidly increases the balance of yang and eventually cause hyperactivity of ministerial fire. Conclusion : It is estimated that the eating habits of modern people cause the process of yang, making them feel restless, impatient and aggressive.

• Journal of Distribution Science
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• v.17 no.2
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• pp.13-23
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• 2019

Purpose - Corporate activities for enhancing and improving corporate performance can largely be divided into exploration and exploitation. The purpose of this study is to examine the impact of implementing organizational ambidexterity in SMEs, including distribution firms, by reviewing the extant literature and deriving the basis on which this strategy affects the managerial performance. Research, design, and methodology - The study uses a systematic review methodology, which employs a structured process to discern trends and meaningful themes across a wide body of literature on specific subjects and research questions. This qualitative study examined the influence of ambidextrous strategies of SMEs on firm performance, and the results were synthesized from the literature. Results - Organizational ambidexterity in SMEs is related to the firm's managerial performance. However, it is crucial to know that there are many ways to generate an ambidextrous organization, and decisions about what method to choose should be based on the environmental aspects of the enterprise. Conclusions - The following aspects should be considered for execution; : making practical decisions based on accurate information about the resources the firm has, considering the organizational level of human resources for implementing organizational ambidexterity, and sharing specific performance goals.