• Journal of the Korean Society of Marine Environment & Safety
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• v.12 no.1 s.24
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• pp.39-45
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• 2006

Based on the previous studies on alcohol effects on human behaviour and performance in transportation system such as air-plane and car driving, the alcohol exposure before and on watch of a ship has a great influence on subsequent behaviour. In this paper, to examine the drinking status of officers on board multiple choice questionnaires are circularized under instruction and surveyed for 118 officers. According to the results of the questionnaire survey on alcohol dependency (Alcoholism) that was invented by WHO, over 27 % of those surveyed represented alcohol abuse symptoms. In addition to that, the existing state and awareness for on-board-drinking was summarized to make a scenario of drink-operation with a ship handling simulator to investigate the effect of alcohol (0.08 g% blood alcohol concentrations) on ship operational performance. A main effect for alcohol was found indicating that ship operational performance was comparatively impaired by this alcohol relative to performance in the non-alcohol condition The results of this research can be applied to minimize marine accidents as basic data.

• Journal of Preventive Medicine and Public Health
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• v.30 no.3 s.58
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• pp.518-529
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• 1997

1,281 male subjects who had been examined more than 3 times for regular check-up in one human dock center of the university hospital were studied between 1990-1995, to evaluate the effect of health counselling with life style and $\gamma-GTP$ value between 1054 normal group without intervention and 227 abnormal group with intervention, ages from 30 to 69 years old. Total mean value of $\gamma-GTP$ was $45.7{\pm}40.7$ unit with highest $\gamma-GTP$ value in age group 50-59 on initial examination. Total abnormal rate was 17.7% with the highest abnormal rate of 18.6% in age group 50-59. Initially, the value of $\gamma-GTP$ was significantly different according to the degree of alcohol intake, relative weight and smoking in normal group(p<0.01) not in abnormal group. In conclusion, the value of $\gamma-GTP$ were significantly increasing in normal group without intervention and significantly decreasing in abnormal group with intervention(p<0.05), which suggests the effect of health counselling, such as the recommendation to change the health behaviour.

• Advances in aircraft and spacecraft science
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• v.3 no.1
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• pp.61-75
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• 2016

Climate changes brought on by human interventions have proved to be more devastating than predicted during the recent decades. Recognition of seriousness of the situation has led regulatory organisations to impose strict targets on allowable carbon dioxide emissions from automotive vehicles. As a possible solution, it has been proposed that Fibre Metal Laminate (FML) system is used to reduce the weight of future vehicles. To facilitate this investigation, FML based on steel and self-reinforced polypropylene was stamp formed into dome shapes under different blank holder forces (BHFs) at room temperature and its forming behaviour analysed. An open-die configuration was used in a hydraulic press so that a 3D photogrammetric measurement system (ARAMIS) could capture real-time surface strains. This paper presents findings on strain evolutions at different points along and at $45^{\circ}$ to fibre directions of circular FML blank, through various stages of forming. It was found initiation and rate of deformation varied with distance from the pole, that the mode of deformations range from biaxial stretching at the pole to drawing towards flange region, at decreasing magnitudes away from the pole in general. More uniform strain distribution was observed for the FML compared to that of plain steel and the most significant effects of BHF were its influence on forming depth and level of strain reached before failure.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.8
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• pp.4019-4023
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• 2016

Background: Colorectal cancer (CRC) or bowel cancer is one of the most important cancer diseases, needing serious attention. The cell surface receptor gene human epidermal growth factor receptor (EGFR) may have an important role in provoking CRC. In this pharmaceutical era, it is always attempted to identify plant-based drugs for cancer, which will have less side effects for human body, unlike the chemically synthesized marketed drugs having serious side effects. So, in this study the authors tried to assess the activity of two important plant compounds, ferulic acid (FA) and p-coumaric acid (pCA), on CRC. Materials and Methods: FA and pCA were tested for their cytotoxic effects on the human CRC cell line HCT 15 and also checked for the level of gene expression of EGFR by real time PCR analysis. Positive results were confirmed by in silico molecular docking studies using Discovery Studio (DS) 4.0. The drug parallel features of the same compounds were also assessed in silico. Results: Cytotoxicity experiments revealed that both the compounds were efficient in killing CRC cells on a controlled concentration basis. In addition, EGFR expression was down-regulated in the presence of the compounds. Docking studies unveiled that both the compounds were able to inhibit EGFR at its active site. Pharmacokinetic analysis of these compounds opened up their drug like behaviour. Conclusions: The findings of this study emphasize the importance of plant compounds for targeting diseases like CRC.

• Journal of Biomedical Engineering Research
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• v.19 no.5
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• pp.495-502
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• 1998

A mathematical model of viscoelasticity on the material property of human pharyngeal tissue utilizing Y.C. Fung's Quasi-linear viscoelastic theory is proposed based on cyclic load, stress relaxation, incremental load, and uniaxial tensile load tests. The material properties are characterized and compared with other biological materials' results. The mathematical model is proposed by combining two characteristic functions determined from the stress relaxation and uniaxial tensile load tests. The reduced stress relaxation function G(t) and elastic response function S(t) are obtained from stress relaxation test and uniaxial tensile load test results respectively. Then the model describing stress-time history of the tissue is implemented utilizing two functions. The proposed model is evaluated and validated by comparing the model's cyclic behaviour with experimental results. The model data could be utilized as an important information for constructing 3-dimensional biomechanical model of human pharynx using FEM(Finite Element Method).

• Coupled systems mechanics
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• v.8 no.2
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• pp.169-184
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• 2019

This research work presents a study that aims to assess the dynamic structural behaviour and also investigate the human comfort levels of a reinforced concrete building, when subjected to nondeterministic wind dynamic loadings, considering the effect of masonry infills on the global stiffness of the structural model. In general, the masonry fills most of the empty areas within the structural frames of the buildings. Although these masonry infills present structural stiffness, the common practice of engineers is to adopt them as static loads, disregarding the effect of the masonry infills on the global stiffness of the structural system. This way, in this study a numerical model based on sixteen-storey reinforced concrete building with 48 m high and dimensions of $14.20m{\times}15m$ was analysed. This way, static, modal and dynamic analyses were carried out in order to simulate the structural model based on two different strategies: no masonry infills and masonry infills simulated by shell finite elements. In this investigation, the wind action is considered as a nondeterministic process with unstable properties and also random characteristics. The fluctuating parcel of the wind is decomposed into a finite number of harmonic functions proportional to the structure resonant frequency with phase angles randomly determined. The nondeterministic dynamic analysis clearly demonstrates the relevance of a more realistic numerical modelling of the masonry infills, due to the modifications on the global structural stiffness of the building. The maximum displacements and peak accelerations values were reduced when the effect of the masonry infills (structural stiffness) were considered in the dynamic analysis. Finally, it can be concluded that the human comfort evaluation of the sixteen-storey reinforced concrete building can be altered in a favourable way to design.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.26 no.4
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• pp.903-910
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• 2016

As smart mobile devices having touchscreens are growingly deployed, a pattern lock system, which is one of the graphical password systems, has become a major authentication mechanism. However, a user's unlocking behaviour leaves smudges on a touchscreen and they are vulnerable to the so-called smudge attacks. Smudges can help an adversary guess a secret pattern correctly. Several advanced pattern lock systems, such as TinyLock, have been developed to resist the smudge attacks. In this paper, we study an automated smudge attack that employs machine learning techniques and its effectiveness in comparison to the human-only smudge attacks. We also compare Android pattern lock and TinyLock schemes in terms of security. Our study shows that the automated smudge attacks are significantly advanced to the human-only attacks with regard to a success ratio, and though the TinyLock system is more secure than the Android pattern lock system.

• KSBB Journal
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• v.16 no.3
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• pp.237-240
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• 2001

Epithelial cell migration plays an important role in many physiological processes such as morphogenesis and wound healing, and cell mobility requires the release of the cell from its adhesion site. This is directed, at least in part, by limited proteolysis of matrix molecules by matrix metalloproteinases (MMPs). MMPs are zinc-dependent proteases produced by a variety of cell types, and have a fundamental role in tissue remodelling, tumour invasion and metastasis. In addition, the ability of cells to mediate fibrinolytic agent, plasmin. The purpose of this study was to test if vascular endothlial growth factor (VEGF) can regulate the production of MMPs and plasmin by keratinocyte cells. Supernatants from a human keratinocyte cell line grown in the presence or absence of VEGF (10ng/mL) produced ?2.5 fold increases in cell proliferation, and ?3.0 fold increses in MMP-2 and plasmin levels. Our results suggest that VEGF may modulate keratinocyte cell proliferating activity by increasing the abundance of MMP-2 and plasmin, and indicates a role for VEGF in the regulation of keratinocyte behaviour in wound healing and tissue remodelling.

• Korean Journal of Human Ecology
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• v.10 no.1
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• pp.113-126
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• 2001

The purpose of this study was to investigate clothing behavior and ornaments wear of university students. The subject of this study consists of 241 college students who were attended in Kongju National University. SPSSWIN Program was utilized to calculated frequency(N), mean value(M) and standard deviation(SD) for statistical analysis. Differences among the populations were examined through T-test, F-test, $x^2$-test. The results of this study were as follow : 1. Clothing behavior of university students had significant difference according to sex, grade. In general, female students showed higher score than did male students in clothing interest, clothing conformity, self-estimation about clothing, clothing dependence, clothing aesthetic, clothing modesty, A first-year students had high tendency in clothing interest. 2. The wear of ornaments had significant difference according to variables. Buying the ornaments, most of students sot information in show window and emphasized on design. Male students wanted to have the ornaments of shoes, watch, hat & necklet, but female students wanted to have the ornaments of shoes, earring, necklet & hairpin. 3. Clothing behavior has Influenced university students' ornaments wear. The university students who appeared to be interested in clothes were apparently influenced by peers when selecting ornaments. Ornaments were usually bought in the department store, while belts were among the most popular choices. Students who stressed color when purchasing ornaments showed a high level of interest in and dependence on clothes. On the basic of these results, we can conclude that university students' taste in clothing behavior and use of ornaments wear depend on several different factors. Therefore, it is possible to outline the shift in clothing attitudes during adolescence. In order to understand university students' behaviour concerning clothes, much guidance and various studies on the subject are much recommended.

• KIEAE Journal
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• v.15 no.2
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• pp.27-35
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• 2015

Purpose: Healthcare is on the whole a personal and critical service that consumer's use, whereas hospitalization is as a rule painful, because nature nurtures and Sun Light Luminosity for healthcare settings is considered healing. The performance and design of climate responsive buildings such as AKU requires a detailed study of attributes of climate both at micro as well as macro level. The therapeutic value of contact with nature through window view, greenery and landscape is calculated there. Method: A two prong strategy is been devised for this article, at micro level three typical morphologies are analysed by creating same environment of neighboring building on sun shading chart, radiation and temperature range. Since the analysis of local climate helps to determine the design strategies for hospital Healing Environment which is suitable for Karachi climate; in order to track the macro climatic behaviour, a considerable analysis of psychometrics chart for AKU Karachi are designed on Climate Consultant (CC) and analysed by Machine Learning. Climate Consultant proposes different design strategies suitable for Karachi. And on the other hand time wise illumination sources for clinical area which are then measured on psychrometric chart- according to singular space: multi patient admission, secondly: acute ambulatory ward, and tertiary: multi windowed space according to the mushrabiyah and sky light pattern. Result: Our findings support the hypothesis that windowed wall is 75-80% more healing wall; an accelerated evidence was found for healing at macro level if the form of the hospital is designed according to the climatologically preferences, whereas at micro level: the light resource becomes the staff attentiveness determinant. In Conclusion evidence was provided that the actual form of luminosity results consequently in satisfaction while light entering from several set of windows and other sources might be valued if design according to the healing environment. The data added on the sun shading chart to calculate rays entraining into space in patient room equal to 124416.21 Watts/ meter $m^2$ is calculated as precise healing rate-and is confirmed by questionnaire from patients belonging from each clinical stage having different illnesses.