• Clinics in Shoulder and Elbow
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• 제10권2호
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• pp.236-240
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• 2007

상완골 및 쇄골에서 발생한 만곡 및 가관절증에 대한 보고들은 드물다. 일반적으로 선천성 쇄골 가관절증은 우측 및 쇄골 중심부에서 호발하고 선천성 경골 가관절증과 비교 시 치유가 쉬운 것으로 알려져 있다. 본 저자들은 발생 위치 및 가관절증의 형태가 기존의 선천성 쇄골 가관절증과 다르고, 신경섬유종증과 연관되어 발생한 선천성 쇄골 가관절증을 경험하여 문헌 고찰과 함께 보고하는 바이다.

• Annals of dermatology
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• 제30권6호
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• pp.712-715
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• 2018

Desmoplastic fibroblastoma is a rare fibrous tumor that usually presents as a painless, slow-growing mass in the subcutaneous tissues and skeletal muscles. It has a wide anatomic distribution, with the most common involvement being the arm and shoulder. Here, we report a case of a tiny painful desmoplastic fibroblastoma arising on the scalp. According to a microscopic examination, this tumor was composed of spindle-shaped fibroblasts in the dense collagenous stroma. On immunohistochemical staining, tumor cells were positive for vimentin and negative for smooth muscle actin, CD34, and S100. Our case is unique in that desmoplastic fibroblastoma developed on the scalp and there was presence of pain despite its small size.

• 대한두개안면성형외과학회지
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• 제22권3호
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• pp.164-167
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• 2021

Reconstruction of lip defects is important because the lips play an important role in maintaining aesthetic facial balance, facial expressions, and speech. There are various methods of lip reconstruction such as primary repair, skin grafting, and utilization of local and free flaps. It is important to select a proper reconstruction method according to the size and location of lip defect. Failure to select an appropriate method may result in distortion, color mismatch, sensory loss, and aesthetic imbalance. Herein we present a case of successful aesthetic reconstruction of the lower vermilion. We removed a venous malformation, which was limited to the lower vermilion and adjacent to the white roll, and repaired the defect using the modified O-Z flap.

• Journal of Chest Surgery
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• 제56권1호
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• pp.1-5
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• 2023

Background: The number of patients with incidentally identified pulmonary nodules is increasing. This study attempted to confirm the usefulness and safety of video-assisted thoracic surgery (VATS) core needle biopsy of pulmonary nodules. Methods: Data from 18 patients diagnosed with pulmonary nodules who underwent VATS core need biopsy were retrospectively reviewed. Results: Of the 18 patients, 15 had malignancies (primary lung cancer, n=14; metastatic lung cancer, n=1), and 3 had benign nodules. Mortality and pleural metastasis did not occur during the follow-up period. Conclusion: In patients with solitary pulmonary nodules that require tissue confirmation, computed tomography-guided percutaneous cutting needle biopsy or diagnostic pulmonary resection sometimes may not be feasible choices due to the location of the solitary pulmonary nodule or the patient's impaired pulmonary function, VATS core needle biopsy may be performed in these patients as an alternative method.

• Safety and Health at Work
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• 제14권1호
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• pp.131-134
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• 2023

The aim was to describe out-of-hospital cardiac arrest (OHCA) occurring in the workplace of a large emergency network, and compare the evolution of their management in the last 15 years. A retrospective study based on data from the Northern Alps Emergency Network compared characteristics of OHCA between cases in and out the workplace, and between cases occurring from January 2004 to December 2010 and from January 2011 to December 2017. Among the 15,320 OHCA cases included, 320 occurred in the workplace (2.1%). They were more often in younger men, and happened more frequently in an area with access to public defibrillation, had more often a shockable rhythm, had a cardiopulmonary resuscitation started by a bystander more frequently, and had a better outcome. Cardiopulmonary resuscitation started by a bystander was the only chain of survival link that improved for cases occurring after December 2010. Workplace OHCA seems to be managed more effectively than others; however, only a slight survival improvement was observed, suggesting that progress is still needed.

• 대한중풍순환신경학회지
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• 제18권1호
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• pp.55-65
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• 2017

■ Objectives Atrial fibrillation is the most common cause of cardioembolic stroke. Of the 44 ischemic stroke patients with atrial fibrillation who were hospitalized in hospital of Korean Medicine from July 1, 2014 to June 30, 2017, we selected 39 patients who have had Magnetic Resonance Angiography. We divided them into Atrial Fibrillation group with no stenosis or less than 50% stenosis in the ipsilateral artery of the lesion and Artery to Artery Embolism group with more than 50% stenosis or occlusion in the ipsilateral artery of the lesion. ■ Methods Clinical characteristics, examination and evaluation tools were collected from the patient's electronic medical records. CHADS2, Initial National Institutes of Health Stroke Scale, 8-item Stroke Scale and Improved 8-item Stroke Scale Number were checked. ■ Results & Atrial Fibrillation group showed differences in age, brain lesion location, vascular lesion, Conclusion initial National Institutes of Health Stroke Scale, initial 8-item Stroke Scale and progress compared to Artery to Artery Embolism group.

• BMB Reports
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• 제52권9호
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• pp.566-571
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• 2019

Lymphoma is one of the most curable types of cancer. However, drug resistance is the main challenge faced in lymphoma treatment. Peroxisomal acyl-CoA oxidase 1 (ACOX1) is the rate-limiting enzyme in fatty acid ${\beta}$-oxidation. Deregulation of ACOX1 has been linked to peroxisomal disorders and carcinogenesis in the liver. Currently, there is no information about the function of ACOX1 in lymphoma. In this study, we found that upregulation of ACOX1 promoted proliferation in lymphoma cells, while downregulation of ACOX1 inhibited proliferation and induced apoptosis. Additionally, overexpression of ACOX1 increased resistance to doxorubicin, while suppression of ACOX1 expression markedly potentiated doxorubicin-induced apoptosis. Interestingly, downregulation of ACOX1 promoted mitochondrial location of Bad, reduced mitochondrial membrane potential and provoked apoptosis by activating caspase-9 and caspase-3 related apoptotic pathway. Overexpression of ACOX1 alleviated doxorubicin-induced activation of caspase-9 and caspase-3 and decrease of mitochondrial membrane potential. Importantly, downregulation of ACOX1 increased p73, but not p53, expression. p73 expression was critical for apoptosis induction induced by ACOX1 downregulation. Also, overexpression of ACOX1 significantly reduced stability of p73 protein thereby reducing p73 expression. Thus, our study indicated that suppression of ACOX1 could be a novel and effective approach for treatment of lymphoma.

• 한국통신학회논문지
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• 제37권5C호
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• pp.410-419
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• 2012

본 논문에서는 병원 실내 위치기반 의료정보 푸쉬 서비스를 위한 안전하고 효율적인 익명 인증 스킴을 제안한다. 제안한 스킴은 다음과 같은 장점들을 가진다. (1)안전한 일방향 해쉬 함수(secure one-way hash function)를 사용하여 의료 서비스 사용자와 의료 관리센터 사이에 연산 복잡성을 최소화 하였다. (2)의료 관리센터 측에 삽입공격(insertion attacks) 및 훔친 검증자 공격(stolen-verifier attacks) 등 다양한 암호학적 공격들에 대한 대상이 될 수 있는 민감한 정보를 저장하는 검증 테이블(verification table)을 전혀 필요로 하지 않는다. (3)안전한 상호 인증과 키 설정(secure mutual authentication and key establishment), 기밀 통신(confidential communication), 사용자 프라이버시(user's privacy), 간단한 키 관리(simple key management), 세션 키 독립성 (session key independence)등을 보장하여 높은 보안 수준을 제공한다. 결론적으로 제안한 스킴은 병원 내 실내 위치기반 의료정보 푸쉬 서비스 환경에서 의료 서비스 사용자와 의료 관리센터 사이에서 아주 낮은 연산 오버헤드를 제공하기 때문에 스마트폰과 같은 경량 디바이스를 이용한 다양한 위치기반 의료정보 서비스 환경에 매우 실용적으로 활용될 수 있다.

• 대한두개안면성형외과학회지
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• 제22권2호
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• pp.78-84
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• 2021

Background: Facial feminization surgery and malarplasty require information concerning facial features in the malar area. Such information varies as a function of sex and race. The objectives of this study aimed to quantitatively evaluate the location of malar prominence across sexes in the Southeast Asian population, and identify sex-specific differences in malar prominence using a combination of two-dimensional (2D) computed tomography (CT) and three-dimensional (3D) CT. Methods: The location of malar prominence was evaluated in 101 Thai adults, consisting of 52 men and 49 women. This study used both 2D CT and 3D CT to achieve greater accuracy, in which 2D CT was used to measure malar distance, malar summit width, facial width, and malar summitto-facial width ratio whereas 3D CT was used to evaluate the positional relationship between the zygomatic summit and four reference points of the zygoma. Results: The malar summit was positioned more laterally in males (p< 0.01) and was more projected in females (p= 0.01). The other 2D-parameters were wider in males. The ratio between the malar summit width and facial width showed similar results for both sexes. The vertical dimension did not show any statistically significant differences; however, a higher summit position was observed in males. Conclusion: The zygomatic summit is positioned more laterally in males and is more projected in females. However, the ratio was similar, which indicates that the male cranium is larger in size. Based on the results in this study, when facial feminization surgery or malarplasty is performed on a Southeast Asian patient, the malar bone should be reduced horizontally and moved forward for better outcomes.

• 한국가스학회지
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• 제25권3호
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• pp.53-58
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• 2021

노년층뿐만 아니라 청년층에 속하는 성인들 사이에서도 병원 외 심장정지(OHCA)를 겪는 심장질환자의 수가 증가하고 있다. 자동심장충격기(AED)는 병원 외 심장정지 환자의 생존율을 개선하는 데 있어 긴요하다. 심장정지 생존율은 제세동 시간에 대하여 지수적으로 감소(decline exponentially)하는 것으로 밝혀졌으나, 자동심장충격기의 최적 배치에 있어 심장정지 생존율의 이러한 특성을 반영한 국내 연구가 미미한 상황이다. 본 연구에서는 자동심장충격기의 최적 입지를 결정하기 위하여 exponential decay coverage 함수를 갖는 최대 gradual coverage 입지 모델에 대하여 고찰하였다. exponential decay coverage 함수는 심장정지 환자의 생존율에 대한 과다추정을 완화한다. 향후 시뮬레이션을 통하여 랜덤한 행인 위치 및 이동을 반영함으로써 행인의 심정지 대응에 있어 창발적인(emergent) 특징을 식별할 수 있는 시설 입지 모델이 개발될 것으로 예측된다.