• Title/Summary/Keyword: Hong Dae-Yong

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Behavior Characteristics of Floating Debris Spilled from the Nakdong River (낙동강 유출 부유쓰레기의 거동 특성)

  • Jang, Seon Woong;Kim, Dae Hyun;Chung, Yong Hyun;Yoon, Hong-Joo
    • Korean Journal of Remote Sensing
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    • v.30 no.1
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    • pp.127-136
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    • 2014
  • When the mouth of the Nakdong River, opens its floodgate, thousands of tons of litter should flown into the South Sea, moving towards nearby coast, thus causing serious social and economic damage. For this reason, in the present study, research was performed on one certain area in northeast coast of Geoje island, which is assumed as area damaged due to rainy season and typhoon in 2012, and research for trace of movement route was implemented by using buoy to identify characteristic of movement of floating debris caused from Nakdong River. Flows related to the movement of floating debris was also identified by analyzing ocean meteorological environment. As a result of the study, total 40 tons of litter composed of grasses and trees(or plants litter) were flown into Heungnam beach on 16th, Jul which is the rainy season. Plus, the location tracking buoy, which was dropped when the typhoon SANBA was coming, was passed by southern sea of Gadeok-do and was flown into Geoje beach 1 ~ 2 days after it was dropped. The wind direction was mostly northeasterly wind around the Geoje beach at the time the buoy and floating debris were flown into northeast coast and there was common sea surface currents which was flowing into the coast.

A Hospital-based Case-control Study on the Risk Factors of Cerebrovascular Disease (뇌혈관질환의 위험요인에 대한 환자 - 대조군 연구)

  • Kim, Jang-Rak;Hong, Dae-Yong;Park, Sung-Hak
    • Journal of Preventive Medicine and Public Health
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    • v.28 no.2 s.50
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    • pp.473-486
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    • 1995
  • A hospital-based, matched case-control study was carried out to evaluate the relation ship of various suspected risk factors including snoring and serum level of cholesterol to cerebrovascular disease in Korea. A total of 127 incident cases of cerebrovascular disease(74 cases of cerebral infarction and 53 cases of intracerebral hemorrhage) admitted to. the department of neurology in a university hospital from December, 1993 to March, 1995 were compared with 127 matched controls admitted to same hospital in same period. A multivariate analysis suggested that ECG abnormality(left ventricular hypertrophy and atrial fibrillation), family history of cerebrovascular disease, fundoscopic abnormality, previous history of transient ischemic attack and hypercholesterolemia were risk factors of cerebrovascular disease, ECG abnormality, fundoscopic abnormality, smoking and hypercholesterolemia were also suggested as risk factors of cerebral infarction.

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Preparation and Biocompatibility of Medical Fiber from Novel Regenerated Cellulose from Styela clava tunic (미더덕껍질의 재생셀룰로오스를 이용한 의료용 섬유의 제조 및 생체적합성)

  • Song, Sung Hwa;Kim, Ji Eun;Choi, Jun Young;Park, Jin Ju;Lee, Mi Rim;Song, Bo Ram;Lee, Yechan;Kim, Hong Sung;Lee, Jae Ho;Lim, Yong;Hwang, Dae Youn;Jung, Young Jin
    • Textile Coloration and Finishing
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    • v.30 no.2
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    • pp.117-129
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    • 2018
  • Cellulose has been widely applied into various medical fields including scaffolding, tissue engineering and tissue formation. In this study, we manufactured cellulose medical fiber from Styela clava tunics(SCT-CS) and analyzed the tensile strength, elongation at break, fluid uptake and surface morphology. And then, the biocompatibility and toxicity of SCT-CS were measured in Sprague-Dawley(SD) rats after the implantation for 30, 60 and 90 days. The level of tensile strength and fluid uptake were lower in SCT-CS than chromic catgut(CCG), while elongation at break level were maintained the higher in SCT-CS. Also, the roughness with pronounced surface patterns as a result of in vivo degradation was significantly greater in CCG than this of SCT-CS although these levels gradually appeared with time in both groups. After implantation for 90 days, SCT-CS and CCG was successfully implanted around muscle of thigh without any significant immune response. Furthermore, no significant alterations were measured in serum parameters and the specific pathological features induced by most toxic compounds for liver and kidney toxicity. Therefore, these results suggest that SCT-CS showing good biocompatibility and non-toxicity can be successfully prepared from cellulose powder of SCT as well as has the potential for use as a powerful biomaterial for medical sutures.

16S rDNA Analysis 9f Bacterial Diversity in Three Fractions of Cow Rumen

  • Cho, Soo-Jeong;Cho, Kye-Man;Shin, Eun-Chule;Lim, Woo-Jin;Hong, Su-Young;Choi, Byoung-Rock;Kang, Jung-Mi;Lee, Sun-Mi;Kim, Yong-Hee;Kim, Hoon;Yun, Han-Dae
    • Journal of Microbiology and Biotechnology
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    • v.16 no.1
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    • pp.92-101
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    • 2006
  • The bacterial diversity of the bovine rumen was examined using a PCR-based approach. 16S rDNA sequences were amplified and cloned from three fractions of rumen (solid, fluid, and epithelium) that are likely to represent different bacterial niches. A total of 113 clones were sequenced, and similarities to known l6S rDNA sequences were examined. About $47.8\%$ of the sequences had $90-97\%$ similarity to 16S rDNA database sequences. Furthermore, about $62.2\%$ of the sequences were $98-100\%$ similar to 16S rDNA database sequences. For the remaining $6.1\%$, the similarity was less than $90\%$. Phylogenetic analysis was also used to infer the makeup of the bacterial communities in the different rumen fractions. The Cytophaga-Flexibacter-Bacteroides group (CFB, $67.5\%$), low G+C Gram-positive bacteria (LGCGPB, $30\%$), and Proteobacteria $(2.5\%)$ were represented in the rumen fluid clone set; LGCGPB $(75.7\%)$, CFB$(10.8\%)$, Proteobacteria $(5.4\%)$, high G+C Gram-positive bacteria (HGCGPB, $5.4\%$), and Spirochaetes $(2.7\%)$ were represented in the rumen solid clone set; and the CFB group $(94.4\%)$ and LGCGPB $(5.6\%)$ were represented in the rumen epithelium clone set. These findings suggest that the rumen fluid, solid, and epithelium support different microbial populations that may play specific roles in rumen function.

Effects of Naloxone on Morphine Analgesia and Spinal c-fos Expression in Rat Formalin Test (Naloxone이 흰쥐 Formalin Test에서 Morphine의 진통효과와 척수 c-fos 유전자 발현에 미치는 영향)

  • Song, Sun Ok;Seok, Je Hong;Lee, Deok Hee;Park, Dae Pal;Kim, Seong Yong;Lim, Jeong Sook;Song, Sun Kyo;Lee, Nam Hyuk
    • The Korean Journal of Pain
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    • v.18 no.2
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    • pp.124-132
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    • 2005
  • Background: This study was performed to evaluate the dose-related effects of naloxone on morphine analgesia in the rat formalin test, and observe the correlation of pain behavior and spinal c-fos expression induced by a formalin injection. Methods: Fifty rats were divided into five groups; control, morphine (morphine pre-treated, intra-peritoneal injection of 0.1 mg of morphine 5 min prior to formalin injection), and three naloxone groups, which were divided according to the administered dose-ratio of naloxone to morphine 20 : 1 ($5{\mu}g$), 10 : 1 ($10{\mu}g$), and 1 : 1 ($100{\mu}g$) representing the low-, medium-, and high-dose naloxone groups, respectively, were injected intra-peritoneally 16 min after a formalin. A fifty ul of 5% formalin was injected into the right hind paw. All rats were observed for their pain behavior according to the number of flinches during phases 1 (2-3, 5-6 min) and 2 (1 min per every 5 min from 10 to 61 min). The spinal c-fos expression was quantitatively analyzed at 1 and 2 hours after the formalin injection using a real-time PCR. Results: The morphine pre-treated (morphine and three naloxone) groups during phase 1, and the morphine, low- and medium-dose naloxone groups during phase 2, showed significantly less flinches compared to those of the control (P < 0.05). In the three naloxone groups, the numbers of flinches were transiently reduced following the naloxone injection in the low- and medium-dose groups compared to those of the morphine group (P < 0.05). The duration of the reduced flinches was longer in the medium-dose group (P < 0.05). The high-dose group revealed immediate increases in flinches immediately after the naloxone injection compared to those of the morphine, low- and medium-dose groups (P < 0.05 for each). The spinal c-fos expression showed no significant patterns between the experimental groups. Conclusions: Our data suggest that relatively low-dose naloxone (1/20 to 1/10 dose-ratio of morphine) transiently potentiates morphine analgesia; whereas, high-dose (equal dose-ratio of morphine) reverses the analgesia, and the spinal c-fos expression does not always correlate with pain behavior in the rat formalin test.

Current Status of the Spent Filter Waste and Consideration of Its Treatment Method in KAERI (KAERI 저장 폐필터의 현황과 처리방법에 관한 고찰)

  • Ji, Young-Yong;Hong, Dae-Seok;Kang, Il-Sik;Shon, Jong-Sik
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.5 no.3
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    • pp.257-265
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    • 2007
  • Spent filter wastes of about 1,000 units (200 L) have been stored in the waste storage facility of the Korea Atomic Energy Research Institute since its operation. At the moment, to secure space in a waste storage facility as well as to efficiently manage spent filter wastes, it is necessary to conduct a compaction treatment of these spent filters, and finally, to repack the compacted spent filters into a 200 liter drum. To do that, the spent filter wastes were first classified according to their generation facilities, their generation date and their surface dose rate by investigating the inventory of the spent filters. In order to repack a compacted spent filter in a 200 liter drum, it is first necessary to conduct a radionuclide assessment of a spent filter before compacting it. Therefore, after taking a representative sample from a spent filter without a dismantlement, the nuclide analysis for it will be conducted. And then, after putting a spent filter into a regular drum by conducting the columnar shaping of the hexahedral form of a spent filter, the compaction treatment of the shaped spent filter will be conducted by vertically compacting it.

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Consideration of the Effect of Artifact during the Image Guided Radiation Therapy Using the Fiducial Marker (영상 유도 방사선치료 시 Fiducial Marker의 Artifact에 관한 연구)

  • Kim, Jong-Min;Kim, Dae-Sup;Back, Geum-Mun;Kang, Tae-Yeong;Hong, Dong-Ki;Yun, Hwa-Yong;Kwon, Kyeong-Tae
    • The Journal of Korean Society for Radiation Therapy
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    • v.22 no.1
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    • pp.1-10
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    • 2010
  • Purpose: The effect of artifact was analyzed, which occurs from fiducial marker during the liver Image Guided Radiation Therapy (IGRT) using the fiducial marker. Materials and Methods: The size of artifact of fixed fiducial marker and length of mobile fiducial marker locus were measured using the On-Board Imager system (OBI) and CT simulator, and 2D-2D matching and 3D-3D matching were carried out, respectively, and at this time, the coordinates transition value of couch was analyzed. Results: The measurement of fixed fiducial marker artifact size indicated CT 4.90, 8.10, 12.90, 19.70 mm and OBI 5.60, 10.60, 14.70, 29.40 mm based on the reference CT slice thickness of 1.25, 2.50, 5.00, and 10.00 mm. Meanwhile, the measurement of mobile fiducial marker locus length indicated CT 42.00, 43.10, 46.50 mm, and OBI 43.40, 46.00, 49.30 mm. The coordinates transition of 1.00, 2.00, and 8.00 mm occurred between 2D-2D matching and 3D-3D matching. Conclusion: It was confirmed that the therapy error increased during IGRT due to the influence of artifact when CT slice thickness increased. Thus, it may be desirable to acquire the image less than 2.50 mm in slice thickness when IGRT is implemented using the fiducial marker.

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Anti-mycobacterial Effects of the Extract of Humulus japonicus (환삼덩굴(Humulus japonicus) 추출물의 항결핵 효과)

  • Hong, Min-Sun;Son, Eun-Soon;Lee, Sung-Joong;Lee, Sun-Kyoung;Lee, Ye-Jin;Song, Sun-Dae;Cho, Sang-Nae;Barry, Clifton E. III;Eum, Seok-Yong
    • Korean Journal of Food Science and Technology
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    • v.46 no.1
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    • pp.94-99
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    • 2014
  • The present study aimed to evaluate the in vitro antimycobacterial effects of hop plant, Humulus japonicus. Methanol extract of H. japonicus (MeOH extract) showed strong direct bactericidal effects against Mycobacterium tuberculosis in vitro. Furthermore, the MeOH extract significantly inhibited M. tuberculosis growth in human macrophages. When five fractions obtained from MeOH extract were examined using the same methods, the hexane and ethyl acetate fractions showed bactericidal effects against M. tuberculosis in vitro, whereas the butanol and water fractions inhibited M. tuberculosis growth in macrophages. Because H. japonicus extract exhibited antimycobacterial activity against both free M. tuberculosis in culture medium and intracellular M. tuberculosis in human macrophages, this plant might be a good candidate for development of a new anti-tuberculosis drug.

Korean research project on the integrated exposure assessment of hazardous substances for food safety

  • Lim, Ji-Ae;Kwon, Ho-Jang;Ha, Mina;Kim, Ho;Oh, Se Young;Kim, Jeong Seon;Lee, Sang-Ah;Park, Jung-Duck;Hong, Young-Seoub;Sohn, Seok-Joon;Pyo, Heesoo;Park, Kyung Su;Lee, Kwang-Geun;Kim, Yong Dae;Jun, Sangil;Hwang, Myung Sil
    • Environmental Analysis Health and Toxicology
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    • v.30
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    • pp.4.1-4.11
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    • 2015
  • Objectives: This survey was designed to conduct the first nationwide dietary exposure assessment on hazardous substances including the intakes of functional food and herbal medicine. In this paper, we introduced the survey design and the results of the dietary exposure status and internal exposure levels of lead (Pb), cadmium (Cd), and mercury (Hg). Methods: We selected 4867 subjects of all ages throughout Korea. We conducted a food survey, dietary survey, biomonitoring, and health survey. Results: Pb and Cd were the highest (median value) in the seaweed ($94.2{\mu}g/kg$ for Pb; $594{\mu}g/kg$ for Cd), and Hg was the highest in the fish ($46.4{\mu}g/kg$). The dietary exposure level (median value) of Pb was $0.14{\mu}g/kg$ body weight (bw)/d, $0.18{\mu}g/kg$ bw/d for Cd, and $0.07{\mu}g/kg$ bw/d for Hg. Those with a blood Pb level of less than $5.00{\mu}g/dL$ (US Centers for Disease Control and Prevention, reference value for those 1 to 5 years of age) were 99.0% of all the subjects. Those with a blood Cd level with less than $0.30{\mu}g/L$ (German Federal Environmental Agency, reference value for non-smoking children) were 24.5%. For those with a blood Hg level with less than $5.00{\mu}g/L$ (human biomonitoring I, references value for children and adults, German Federal Environmental Agency) was 81.0 % of all the subjects. Conclusions: The main dietary exposure of heavy metals occurs through food consumed in a large quantity and high frequency. The blood Hg level and dietary exposure level of Hg were both higher than those in the European Union.

Effects of Aerobic Exercises and Complex Exercises during 12 Weeks on Blood Lipid in Middle Aged Women according to Body Composition (중년여성의 체구성에 따른 12주 유산소 운동과 복합성 운동이 혈중지질에 미치는 영향)

  • Kim, Joung-Woo;Lee, Moo-Sik;Na, Baeg-Ju;Lee, Jin-Yong;Hong, Jee-Young;Kim, Dae-Kyung;Lee, Bo-Woo
    • Proceedings of the KAIS Fall Conference
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    • 2010.11b
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    • pp.915-918
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    • 2010
  • 12주간의 유산소 운동 및 복합성 운동이 중년여성의 신체 구성 및 혈중 지질에 미치는 영향을 규명하기 위해 2009년 3월부터 9월까지 일개 D광역시 소재 일개 S구 보건소 12주 운동프로그램에 참가한 40~50대 중년 여성 78명을 대상으로 비만그룹과 정상그룹으로 나누어 주3회, 회당 80분의 유산소 운동과 유산소운동/근력 운동을 병행한 복합성 운동을 목표 심박수 40~60%에서 실시하였다. 1. WHO 기준 적용 시, 정상군의 경우 운동의 유형에 상관없이 유의한 차이가 나타났다. 2. WHO 기준 적용 시, 비만군의 경우 유산소 운동의 근육량, 체지방량, 체지방률을 제외하고 운동의 유형에 상관없이 유의한 차이가 나타났다. 3. 아시아-태평양 기준 적용 시, 정상군의 경우 일부 항목에서만 유의한 차이가 나타났다. 4. 아시아-태평양 기준 적용 시, 비만군의 경우 유산소 운동의 근육량을 제외하고 운동의 유형에 상관 없이 유의한 차이가 나타났다. 상기 결론에서 볼 수 있듯이, 12주간의 운동 프로그램은 WHO 기준 적용 시 일부 항목을 제외하고 운동 유형에 상관없이 40~50대 중년여성의 신체조성 및 혈중지질에 긍정적 효과를 미치는 것으로 판단된다. 그러나 비만에 대해 더 엄격한 아시아 - 태평양 기준 적용 시 특히 정상 군에서 유의한 차이를 보이지 않는 항목이 많이 나타났는데 이것은 우리나라 비만기준을 아시아태평양기준에서 세계 기준으로 바꿀 필요가 있다는 주장을 뒷받침하고 있다. 세계보건기구 WHO는 2004년에 이미 우리나라에 세계비만기준을 따를 것을 권고했는데, 실제 위험성이 정확하게 평가돼야지 정확한 대책이나 관리가 나올 수 있기 때문이다. WHO 기준에 의거 시 질병의 발생 위험도가 낮은 경도비만이 엄격한 아시아-태평양 지역 기준 적용 시 비만으로 분류되어 불필요하게 체형에 대한 부정적인 이미지나 스트레스를 받을 가능성도 있다.

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