• 제목/요약/키워드: Histological characteristics

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결핵성 경부 림프절염의 병리소견과 항산균 검출 및 임상소견에 관한연구 (Cervical Tuberculous Lymphadenitis : Clinicopathological Features and AFB Positivity)

  • 황영준;고미혜;윤세영;김용호;김도형;이계영;김건열;명나혜;박재석
    • Tuberculosis and Respiratory Diseases
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    • 제48권5호
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    • pp.720-729
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    • 2000
  • 연구배경 : 결핵의 병리소견은 하나의 스펙트럼을 이루는데, 결핵균에 대한 면역기능이 정상이면 육아종의 형성이 좋고 결핵균이 거의 발견되지 않지만, 결핵균에 대한 면역 기능이 저하되어 있으면 육아종의 형성이 나쁘며 많은 결해균이 발견된다. 이에 저자들은 결핵성 경부 림프절염 환자의 림프절 조직에서 결핵균에 대한 면역기능의 정도를 알아보기 위해 병리소견과 항산균의 유무를 분석하고 임상적인 특징과 관련이 있는지 알아보고자 하였다. 방법 : 조직검사로 결핵성 경부 림프절염으로 진단받은 33명의 환자들의 병리소견을 분석하고 조직표본들을 탈파라핀화한 후 auramine-rhodamine 염색을 시행하여 조직에서의 항산균 유무를 검사한 후, 조직에서의 결핵균 검출 유무가 병리적인 특성(육아종의 형성정도, 건락성 과시의 유무, 중성구의 침윤) 또는 임상적인 특성(림프절의 크기, 림프절의 발견시점에서 조직검사까지의 기간, 림프절 부위의 통증이나 압통의 유무, 흉부방사선 소견상 결핵 소견의 유무)과 연관성이 있는지 알아보았다. 결과 : 1) 대상환자의 평균연령은 42.4세였고, 남녀비는 1:4.5였다. 2) 조직검사 소견 상 모든 예에서 육아종의 형성이 좋았고, 다양한 정도의 건락성 괴사가 관찰되었으며, 39%에서 육아종성 염증 주위로 다형백혈구의 침윤이 관찰되었다. 3) 52%의 예에서 조직표본에서 항산균이 검출되었고, 항산균은 세포 외에 존재하였고, 건락성괴사 부위의 가장자리에서 주로 발견되었다. 4) 조직에서의 항산균 검출 유무와 병리학적 특성 또는 임상적 특성과는 연관성이 없었다. 결론 : 결핵성 경부 림프절염의 경우 육아종의 형성이 좋았고, 조직에서의 항산균 검출 유무와 병리적 또는 임상적 특성과는 연관성이 없었다.

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CBCT imaging and histopathological characteristics of osteoradionecrosis and medication-related osteonecrosis of the jaw

  • Ogura, Ichiro;Minami, Yoshiyuki;Ono, Junya;Kanri, Yoriaki;Okada, Yasuo;Igarashi, Kensuke;Haga-Tsujimura, Maiko;Nakahara, Ken;Kobayashi, Eizaburo
    • Imaging Science in Dentistry
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    • 제51권1호
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    • pp.73-80
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    • 2021
  • Purpose: The purpose of this study was to evaluate the cone-beam computed tomographic (CBCT) imaging and histopathological characteristics of osteoradionecrosis(ORN) and medication-related osteonecrosis of the jaw(MRONJ). Materials and Methods: Ten surgical specimens from segmental mandibulectomy (3 ORN and 7 MRONJ) were analyzed using CBCT. The CBCT parameters were as follows: high-resolution mode (tube voltage, 90.0 kV; tube current, 4.00 mA; rotation time, 16.8 s; field of view, 56 mm×56 mm; thickness, 0.099 mm). Histopathological characteristics were evaluated using histological slides of the surgical specimens. The Pearson chi-square test was used to compare ORN and MRONJ in terms of CBCT findings(internal texture, sequestrum, periosteal reaction and cortical perforation) and histopathological characteristics(necrotic bone, inflammatory cells, reactive bone formation, bacteria, Actinomyces, and osteoclasts). A P value less than 0.05 was considered to indicate statistical significance. Results: MRONJ showed periosteal reaction on CBCT more frequently than ORN (7 of 7 [100%] vs. 0 of 3 [0%], P<0.05). Regarding histopathological characteristics, MRONJ showed osteoclasts more frequently than ORN (6 of 7 [85.7%] vs. 0 of 3 [0%], P<0.05). Conclusion: This study evaluated the CBCT imaging and histopathological characteristics of ORN and MRONJ, and the findings suggest that CBCT could be useful for the evaluation of ORN and MRONJ.

한국산(韓國産) 고등(高等) 균류(菌類)의 분류학적(分類學的) 연구(硏究)(IV) (Taxonomic Investigations on Korean Higher Fungi(IV))

  • 김병각;김두하;최응칠;심미자
    • 한국균학회지
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    • 제4권1호
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    • pp.17-25
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    • 1976
  • 1976년 7월${\sim}$9월에 경기도(京畿道) 및 서울지방(地方)에서 채집(採集)한 고등(高等) 균류중(菌類中) 다음 9종(種), Amanita griseofarinosa, Pholiota spectabilis, Pholiota vermiflua, Boletus erythroporus, Russula alutacea, Russula chameleontina, Russula xerampelina and Polyporus sulphureus 및 Mycena haematopoda는 한국(韓國) 미기록종(未記綠種)임을 보고(報告)한다.

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간아세포종의 세침흡인 세포학적 소견 -2예 증례보고- (Fine Needle Aspiration Cytology of Hepatoblastoma -Report of Two Cases-)

  • 박영년;이광길;박찬일
    • 대한세포병리학회지
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    • 제1권1호
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    • pp.98-102
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    • 1990
  • Hepatoblastoma (HB) is a rare embryonic malignant tumor of the liver. Most morphological studies on HB have limited to the histological characteristics and only 3 cases of HB have been described in the cytology literature. We present 2 cases of HB occurring in children aged 1 year and 3 years, respectively. The distinctive cytologic features of fine needle aspiration of HB were clusters of tumor cells showing acinar and trabecular pattern, smaller tumor cells with a high nuclear-cytopalsmic ratio and hyperchromatic nuclei having prominent nucleoli, and the presence of extramedullary hematopoiesis and osteoid material. These features were also found in the cell block and the biopsy specimen, and appeared very useful in the differentiation of HB from hepatocellular carcinoma.

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Adenoid cystic carcinoma of the sublingual gland: A case report

  • Song, Ji-Young
    • Imaging Science in Dentistry
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    • 제46권4호
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    • pp.291-296
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    • 2016
  • Adenoid cystic carcinoma (ACC) of the sublingual gland is an extremely rare neoplasm. The clinicopathological characteristics of ACC are slow-growing swelling with or without ulceration, perineural spread, local recurrence, and distant metastasis. This report describes a 58-year-old male who had a slowly growing swelling without ulceration on the right side of the mouth floor that had been present for 1 month. In a radiological examination, the mass showed multilocular cystic features and no bony or tongue muscle invasion. No enlarged cervical lymph nodes were detected. Excisional biopsy and histological analysis showed that the lesion was ACC. In addition to reporting a rare case of ACC, this report also discusses the differential diagnosis and treatment of ACC with a review of the relevant literature.

최신 치아우식 진단기준 : International Caries Detection and Assessment System (ICDAS) (International Caries Detection and Assessment System (ICDAS))

  • 최연희
    • 대한치과의사협회지
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    • 제49권8호
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    • pp.451-460
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    • 2011
  • Dental caries has been widely prevalent with presence of cavitation on teeth. For the last several decades, the prevalence of dental caries in developed countries has rapidly decreased so there has been needed a new and detailed diagnostic guideline to differentiate the severity of dental caries, especially for early status of caries. The cariology specifically requires the development of an integrated definition of dental caries and uniform systems for measuring the caries process in the fields of clinical diagnosis and treatment, epidemiological researches, and dental education and so forth. The international Caries Detection and Assessment System (ICDAS) optically measures the enamel surface changes and potential histological depth of carious lesions by relying on surface characteristics of teeth. ICDAS is a visual classification system that was developed to diagnose the subtle changes of enamel surface, predict the progress direction of early caries, allow standardized data collection in relation to caries in different settings, and to enable better comparison of oral health between countries worldwide and research studies.

Gonadal Development and Reproduction in the Trumpet Shell, Charonia sauliae

  • 강경호;김재민;선승찬;;;김현정
    • 한국패류학회지
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    • 제25권1호
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    • pp.29-33
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    • 2009
  • This study devised and tested a histological staging system for gonadal development in the trumpet shell, Charonia sauliae, which was collected along the south coast of Jeju Island, South Korea. This paper details for the first time the gonadal development characteristics of C. sauliae. Ovary and testis development in C. sauliae can be roughly divided into five stages: growing, mature, spent, degenerative, and resting. The trumpet shelll has multiple fecundation and fertilization during the spawning season for out-of-step gonadal development in high-temperature and low-salinity environments. Female trumpet shell tended to have larger shells and were more abundant than males (64.26% of all animals collected were female).

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임파양과오종 1례보고 (Lymphoid Harmatoma in the Mediastinum -A case report-)

  • 진재권;박주철;유세영
    • Journal of Chest Surgery
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    • 제12권2호
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    • pp.101-104
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    • 1979
  • Lymphoid hamartomas are a rare benign disease which can be easily treated by complete surgical excision. They developed most often in the thorax, and can be discovered usually on routine chest X-ray.p But some of them can also be found because of pressure symptoms or the presence of a palpable mass if outside the thorax. We experienced a case of the hyaline-vascular type of lymphoid hamartoma in the left hilum of a 29 year-old Korean male in March, 1979. He was well except intermittent cough and left chest discomfort of a year duration and was treated by resection of the left upper lobe including nodular tumor masses. The histological characteristics were an aggregation of lymphoid follicles composed of concentrically arranged mature lymphocytes with centrally placed thick walled arterioles showing endothelial proliferation and some of them were hyalinized. Between the follicles, there was extensive capillary proliferation and infiltration of numerous lymphocytes, scanty plasma cells and eosinophils.

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Data Mining for Identification of Molecular Targets in Ovarian Cancer

  • Villegas-Ruiz, Vanessa;Juarez-Mendez, Sergio
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권4호
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    • pp.1691-1699
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    • 2016
  • Ovarian cancer is possibly the sixth most common malignancy worldwide, in Mexico representing the fourth leading cause of gynecological cancer death more than 70% being diagnosed at an advanced stage and the survival being very poor. Ovarian tumors are classified according to histological characteristics, epithelial ovarian cancer as the most common (~80%). We here used high-density microarrays and a systems biology approach to identify tissue-associated deregulated genes. Non-malignant ovarian tumors showed a gene expression profile associated with immune mediated inflammatory responses (28 genes), whereas malignant tumors had a gene expression profile related to cell cycle regulation (1,329 genes) and ovarian cell lines to cell cycling and metabolism (1,664 genes).