• The Korean Journal of Physiology and Pharmacology
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• v.3 no.1
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• pp.101-117
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• 1999

Amyotrophic lateral sclerosis (ALS) is a degenerative neuromuscular disease of unknown etiology in which the upper and lower motor neurons are progressively destroyed. Recent evidences support the role of autoimmune mechanisms in the pathogenesis of ALS. This study investigated the effects of sera from ALS patients on neuromuscular transmission in phrenic nerve-hemidiaphragm preparations and on calcium currents of single isolated dorsal root ganglion (DRG) cells in mice. Mice were injected with either control sera from healthy adults or ALS sera from 18 patients with ALS of sporadic form, for three days. Miniature end plate potential (MEPP) and nerve-evoked end plate potential (EPP) were measured using intracellular recording technique and the quantal content was determined. Single isolated DRG cells were voltage-clamped with the whole-cell configuration and membrane currents were recorded. Sera from 14 of 18 ALS patients caused a significant increase in MEPP frequency in normal Ringer's solution $(4.62{\pm}0.14\;Hz)$ compared with the control $(2.18{\pm}0.15\;Hz).$ In a high $Mg^{2+}/low\;Ca^{2+}$ solution, sera from 13 of 18 ALS patients caused a significant increase in MEPP frequency, from $2.18{\pm}0.31$ Hz to $6.09{\pm}0.38$ Hz. Sera from 11 of 18 patients produced a significant increase of nerve-evoked EPP amplitude, from $0.92{\pm}0.05$ mV to $1.30{\pm}0.04$ mV, while the other seven ALS sera did not alter EPP amplitude. In the ALS group, EPP quantal content was also elevated by the sera of 14 patients (from $1.49{\pm}0.07$ to $2.35{\pm}0.07).$ MEPP frequency and amplitude in wobbler mouse were $4.03{\pm}0.53$ Hz and $1.37{\pm}0.18$ mV, respectively, which were significantly higher than those of wobbler controls (wobblers without the symptoms of wobbler). Sera from ALS patients significantly reduced HVA calcium currents of DRG cells to 42.7% at -10 mV. Furthermore, the inactivation curve shifted to more negative potentials with its half-inactivation potential changed by 6.98 mV. There were, however, significant changes neither in the reversal potential of $I_{Ca}$ nor in the I-V curve. From these results it was concluded that: 1) The serum factors of sporadic ALS patients increase neuromuscular transmission and can alter motor nerve terminal presynaptic function. This suggests that ALS serum factors may play an important role in the early stage of ALS, and 2) Calcium currents in DRG cells were reduced and rapidly inactivated by ALS sera, suggesting that in these cells, ALS serum factors may exert interaction with the calcium channel.

• International Journal of Highway Engineering
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• v.12 no.1
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• pp.55-59
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• 2010

High VOC(Vehicle Operating Cost) is the main reason for the rehabilitation of paved road and VOC is composed of fuel consumption, lubricant oil consumption, parts consumption, etc. Fuel consumption is one of the largest components of VOC and the roughness of road represents the deterioration level of the road. For these reasons, the fuel consumption is measured for different IRI(International Roughness Index) in this study. The fuel consumption was measured by processing the voltage signal of fuel injector of vehicle and the speed was measured with GPS. The change rate of fuel consumption for different IRI can be calculated with the results of this test. It's concluded that fuel consumption(L/100km) of medium and large passenger car increases 7 times fast of the increase of IRI(m/km) around 3.5m/km in the speed range of 40 ~ 100km/h, and fuel consumption is the best at 60km/h.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.20 no.1
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• pp.41-47
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• 2006

This paper presents harmonic evaluation of an IAT(Intra Airport Transit) system in Incheon International Airport. It will be used for electric vehicles with 80[kW] per car produced by Mitsubishi Heavy Industries Ltd, and which is constructed with SIV(Static Inverter), VVVF controller and two induction motor. The vehicles operated in the IAT system can be treated as rapidly changing DC loat and at a feeding substation, 3-phase electric power is transferred to DC 750[V] by rectifier. Since vehicles are changing continuously, the voltages for the load fluctuate in the IAT system, and moreover, the voltage fluctuation generates high-order harmonics. It results the difficulty in maintaining power quality in KEPCO systems' side. The power quality of the IAT system in Incheon International Airport is evaluated using PSCAD/EMTDC simulator in the paper. The THD(Total Harmonic Distortion) of voltages and TDD(Total Demand Distortion) of currents, indices are calculated for the IAT system using the results of PSCAD/EMTDC dynamic simulation.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.10 no.3
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• pp.467-472
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• 2006

This study has been done to design a precise system and develop position control algorithm to control a Composite Smoke Bomb Azimuth driving apparatus of a BLDC servo motor. Having to Blind the sight of opposite tank. the Smoke Bomb Rotational driving system needs instant response that is able to detect opponent appearance and blast the bomb at a short time. So a design that shows fast current response capability or $300[Hz]\sim500[Hz]$ is proposed. in the MIN-MAX PWM technology is used to increase the operational speed. in order to control the blasting position, a precision position control algorithm that utilizes the integral value of speed trajectory is suggested. Also these characteristics are monitored and assessed by the PC based monitoring program which shows the graphs of current, voltage, position, and speed parameters. The main controller is based on a TMS320VC33 high performance floating-point DSP(Digital Signal Process) and the PWM generator utilizes EPM7128 CPLD.

• International Journal of Precision Engineering and Manufacturing
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• v.8 no.2
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• pp.44-48
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• 2007

In recent years, the size of plane substrates and semiconductor wafers has increased. As conventional contact transportation systems composed of, for example, carrier rollers, belt conveyers, and robot hands carry these longer and wider substrates, the increased weight results in increased potential for fracture. A noncontact transportation system is required to solve this problem. We propose a new noncontact transportation system combining acoustic viscous and aerostatic forces to provide damage-free transport. In this system, substrates are supported by aerostatic force and transported by acoustic viscous streaming induced by traveling wave deformation of a disk-type stator. A ring-type piezoelectric transducer bonded on the stator excites vibration. A stator with a high Q piezoelectric transducer can generate traveling vibrations with amplitude of $3.2{\mu}m$. Prior to constructing a carrying road for substrates, we clarified the basic properties of this technique and stator vibration characteristics experimentally. We constructed the experimental equipment using a rotational disk with a 95-mm diameter. Electric power was 70 W at an input voltage of 200 Vpp. A rotational torque of $8.5\times10^{-5}Nm$ was obtained when clearance between the stator and disk was $120{\mu}m$. Finally, we constructed a noncontact transport apparatus for polycrystalline silicon wafers $(150(W)\times150(L)\times0.3(t))$, producing a carrying speed of 59.2 mm/s at a clearance of 0.3 mm between the stator and wafer. The carrying force when four stators acted on the wafer was $2\times10^{-3}N$. Thus, the new noncontact transportation system was demonstrated to be effective.

• Journal of Power Electronics
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• v.13 no.3
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• pp.369-380
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• 2013

Direct torque control based on space vector modulation (SVM-DTC) protects the DTC transient merits. Furthermore, it creates better quality steady-state performance in a wide speed range. The modified method of DTC using SVM improves the electrical magnitudes of asynchronous machines, such as minimizing the stator current distortions, the stator flux with electromagnetic torque without ripple, the fast response of the rotor speed, and the constant switching frequency. In this paper, the proposed method is based on two new control strategies for direct torque control with space vector modulation. First, fuzzy logic control is used instead of the PI torque and a PI flux controller to minimizing the torque error and to achieve a constant switching frequency. The voltages in the direct and quadratic reference frame ($V_d$, $V_q$) are achieved by fuzzy logic control. In this scheme, the switching capability of the inverter is fully utilized, which improves the system performance. Second, the close loop of stator flux estimation based on the voltage model and a low pass filter is used to counteract the drawbacks in the open loop of the stator flux such as the problems saturation and dc drift. The response of this new control strategy is compared with DTC-SVM. The experimental and simulation results demonstrate that the proposed control topology outperforms the conventional DTC-SVM in terms of system robustness and eliminating the bad outcome of dc-offset.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.12 no.5
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• pp.529-536
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• 2019

In this paper, the signals of the sensor for extracting characteristic parameters of the rotor are collected and the performance of the extraction technique is analyzed. To this end, a vibration test league was developed for conducting model tests to analyze the signal characteristics under normal operation. As a result, it is judged that no change in the measured the raw data amplitude will occur in the acceleration sensor with the unbalanced mass measured from the acceleration sensor. Performing FFT showed a significant increase in amplitude of the rotational frequency of 20 Hz as the unbalanced mass increased. The analysis results according to the change in the unequal mass of the speed sensor also showed a significant increase in the 1X Harmonics component, such as the acceleration sensor. There was no change in the amplitude of the acceleration sensor data when the misalignment occurred, and for the Envelope data, the amplitude of 2X (40 Hz) was increased depending on the degree of misalignment. The velocity sensor at change of misalignment also showed similar results to the acceleration sensor, and the peak was reduced at 600 Hz as the load increased in the frequency spectrum.

• Journal of the Korean Society of Industry Convergence
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• v.26 no.5
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• pp.953-965
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• 2023

The stratospheric drones are developed to perform missions such as weather observation, communication relay, surveillance, and reconnaissance at 18km to 20km, where climate change is minimal and there is no worry about a collision with aircraft. It uses solar panels for daytime flights and energy stored in batteries for night flights, providing many advantages over existing satellites. The electrical and power systems essential for stratospheric drone flight must ensure reliability, efficiency, and lightness by selecting the optimal circuit topology. Therefore, it is necessary to analyze the circuit topology of various types of multi-level inverters with high redundancy that can ensure the reliability and efficiency of the motor driving power required for stable long-term flight of stratospheric drones. By quantifying the switch element voltage drop and the number and weight of inverter components for each topology, we evaluate efficiency and lightness and propose the most suitable circuit topology for stratospheric drones.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.43 no.11 s.353
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• pp.48-57
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• 2006

This work describes a 12b 200KHz 0.52mA $0.47mm^2$ algorithmic ADC for sensor applications such as motor controls, 3-phase power controls, and CMOS image sensors simultaneously requiring ultra-low power and small size. The proposed ADC is based on the conventional algorithmic architecture with recycling techniques to optimize sampling rate, resolution, chip area, and power consumption. The input SHA with eight input channels for high integration employs a folded-cascode architecture to achieve a required DC gain and a sufficient phase margin. A signal insensitive 3-D fully symmetrical layout with critical signal lines shielded reduces the capacitor and device mismatch of the MDAC. The improved switched bias power-reduction techniques reduce the power consumption of analog amplifiers. Current and voltage references are integrated on the chip with optional off-chip voltage references for low glitch noise. The employed down-sampling clock signal selects the sampling rate of 200KS/s or 10KS/s with a reduced power depending on applications. The prototype ADC in a 0.18um n-well 1P6M CMOS technology demonstrates the measured DNL and INL within 0.76LSB and 2.47LSB. The ADC shows a maximum SNDR and SFDR of 55dB and 70dB at all sampling frequencies up to 200KS/s, respectively. The active die area is $0.47mm^2$ and the chip consumes 0.94mW at 200KS/s and 0.63mW at 10KS/s at a 1.8V supply.