• Title/Summary/Keyword: High Shear Stress

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A Comparative Study of the Hemodynamic Hypotheses for the Generation of Atherosclerosis (동맥경화증의 발생에 관한 혈류역학적 가설들에 대한 비교연구)

  • Suh, Sang-Ho;Cho, Min-Tae;Roh, Hyung-Woon;Kwon, Hyuck-Moon
    • Proceedings of the KSME Conference
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    • 2003.04a
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    • pp.1915-1918
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    • 2003
  • Atherosclerosis, which is a degenerate disease, is believed to occur in the vascular system due to deposition of cholesterol and low density lipoprotein(LDL) or thrombosis on the blood vessel. Atherosclerosis narrows arterial lumen, which is known as stenosis phenomenon of blood vessel. Pathogenesis of atherosclerosis is thought to occur mainly by aging. Restenosis phenomenon is observed in the same site of insertion of a stent and balloon angioplasty after treatment of interventional theraphy. Several hypothetical theories related to the generation of atherosclerosis have been reported: high shear stress theory, low shear stress theory, high shear stress gradient theory, flow separation and turbulence theory and high pressure theory. However, no one theory clearly explains the causes of atherosclerosis. In the present study the generation of atherosclerosis in the left coronary artery is investigated. The hypotheses are verified by using the computer simulation.

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Analysis on Shear Stress During Drawing Process of Pearlite Structure of High Carbon Steel (고탄소강 펄라이트 조직의 인발 공정 시 전단응력의 해석)

  • Kim H. S.;Kim B. M.;Bae C. M.;Lee C. Y.
    • Transactions of Materials Processing
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    • v.14 no.2 s.74
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    • pp.133-138
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    • 2005
  • This paper presents a study on defects in pearlite lamella structure of high carbon steel by means of finite-element method(FEM) simulation. High-carbon pearlite steel wire is characterized by its nano-sized microstructure feature of alternation ferrite and cementite. The likely fatigue crack is located on interface of the lamella structure where the maximum amplitude of the longitudinal shear stress and transverse shear stress was calculated during cyclic loading. The FEM is proposed for maximum shear stress from loading of lamella structure, and a method is predicted to analyze the likely fatigue crack generation. It is possible to obtain the important basic data which can be guaranteed in the ductility of high carbon steel wire by using FEM simulation.

Analysis on Shear Stress During Drawing Process of Pearlite Structure of High Carbon Steel (고탄소강 펄라이트 조직의 인발 공정 시 전단응력의 해석)

  • Kim H. S.;Kim B. M.;Bae C. M.;Lee C. Y,
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2004.10a
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    • pp.93-96
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    • 2004
  • This paper presents a study on defects in pearlite lamella structure of high carbon steel by means of finite-element method(FEM) simulation. High-carbon pearlite steel wire is characterized by its nano-sized microstructure feature of alternation ferrite and cementite. The likely fatigue crack is located on interface of the lamella structure where the maximum amplitude of the longitudinal shear stress and transverse shear stress was calculated during cyclic loading. The FEM is proposed for maximum shear stress from loading of lamella structure, and a method is predicted to analyze the likely fatigue crack generation. It is possible to obtain the important basic data which can be guaranteed in the ductility of high carbon steel wire by using FEM simulation.

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Effect of Oxygen and Shear Stress on Molecular Weight of Hyaluronic Acid Produced by Streptococcus zooepidemicus

  • Duan, Xu-Jie;Yang, Li;Zhang, Xu;Tan, Wen-Song
    • Journal of Microbiology and Biotechnology
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    • v.18 no.4
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    • pp.718-724
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    • 2008
  • Dissolved oxygen (DO) and shear stress have pronounced effects on hyaluronic acid (HA) production, yet various views persist about their effects on the molecular weight of HA. Accordingly, this study investigated the effects of DO and shear stress during HA fermentation. The results showed that both cell growth and HA synthesis were suppressed under anaerobic conditions, and the HA molecular mass was only $(1.22{\pm}0.02){\times}10^6 Da$. Under aerobic conditions, although the DO level produced no change in the biomass or HA yield, a high DO level favored the HA molecular mass, which reached a maximum value of $(2.19{\pm}0.05){\times}10^6 Da$ at 50% DO. Furthermore, a high shear stress delayed the rate of HA synthesis and decreased the HA molecular weight, yet had no clear effect on the HA yield. Therefore, a high DO concentration and mild shear environment would appear to be essential to enhance the HA molecular weight.

Space-Time Characteristics of the Wall Shear-Stress Fluctuations in a Low-Reynolds Number Axial Turbulent Boundary Layer (축방향 난류경계층에서 벽면마찰 섭동량의 공간 및 시간에 따른 특성)

  • 신동신
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.15 no.11
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    • pp.895-901
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    • 2003
  • Direct numerical simulation database of an axial turbulent boundary layer is used to compute frequency and wave number spectra of the wall shear-stress fluctuations in a low-Reynolds number axial turbulent boundary layer. One-dimensional and two-dimensional power spectra of flow variables are calculated and compared. At low wave numbers and frequencies, the power of streamwise shear stress is larger than that of spanwise shear stress, while the powers of both stresses are almost the same at high wave numbers and frequencies. The frequency/streamwise wave number spectra of the wall flow variables show that large-scale fluctuations to the ms value is largest for the streamwise shear stress, while that of small-scale fluctuations to the rms value is largest for pressure. In the two-point auto-correlations, negative correlation occurs in streamwise separations for pressure and spanwise shear stress, and in spanwise correlation for both shear stresses.

Dynamic Shear Stress of Tough-Pitch Copper at High Strain and High Strain-Rate

  • Moon, Wonjoo;Seo, Songwon;Lim, Jaeyoung;Min, Oakkey
    • Journal of Mechanical Science and Technology
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    • v.16 no.11
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    • pp.1412-1419
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    • 2002
  • Dynamic shear tests for the tough-pitch copper at high strain and high strain rate was performed. The Split Hopkinson Pressure Bar (SHPB) compression test system was modified to yield a shear deformation in the specimen. Hat-shaped specimens for the tough-pitch copper were adopted to generate high strain of γ=3~4 and high strain-rate of γ= 10$^4$/s. The dynamic analysis by ABAQUS 5.5/EXPLICIT code verified that shear zone can be localized in hat-shaped specimens. A proper impact velocity and the axial length of the shear localization region wert determined through the elastic wave analysis. The displacement in a hat-shaped specimen is limited by a spacer ring which was installed between the specimen and the incident bar. The shear bands were obtained by measuring the direction of shear deformation and the width of deformed grain in the shear zone. The decrease of specimen length has been measured on the optical displacement transducer. Dynamic shear stress-strain relations in the tough-pitch copper were obtained at two strain-rates.

Effect of Osmotic Stress on Human Red Cell Rheology: Cell Deformability, Aggregability and Blood Viscosity

  • Ku, Yun-Hee;Shin, Se-Hyun;Suh, Jang-Soo
    • International Journal of Vascular Biomedical Engineering
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    • v.4 no.2
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    • pp.7-12
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    • 2006
  • The present study investigated the effects of the osmotic environment on the rheological properties of erythrocytes and their suspensions. In an iso-osmotic medium, erythrocytes forming a biconcave discocyte under resting conditions, exhibited high deformability. In a low-osmotic medium, the deformability of erythrocytes, which swelled and exhibited a spherical shape, significantly decreased at a high shear stress and the high-shear viscosity of the cell suspension was slightly higher than that of normal blood. Hyper-osmotic stress, however, which caused to form echinocytes, decreased cell deformability but exhibited smaller viscosity in low shear rates than iso-osmotic blood viscosity. These results showed a close relation with the aggregability measurements, in that hypertonic blood showed lower aggregability than the hypotonic and isotonic RBC suspensions. These findings indicate that the physicochemical environment has a strong influence on the rheological properties of the erythrocyte and its suspensions.

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Effect of material mechanical differences on shear properties of contact zone composite samples: Experimental and numerical studies

  • Wang, Weiqi;Ye, Yicheng;Wang, Qihu;Liu, Xiaoyun;Yang, Fan;Tan, Wenkan
    • Structural Engineering and Mechanics
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    • v.76 no.2
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    • pp.153-162
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    • 2020
  • Aiming at the mechanical and structural characteristics of the contact zone composite rock, the shear tests and numerical studies were carried out. The effects of the differences in mechanical properties of different materials and the normal stress on shear properties of contact zone composite samples were analyzed from a macro-meso level. The results show that the composite samples have high shear strength, and the interface of different materials has strong adhesion. The differences in mechanical properties of materials weakens the shear strength and increase the shear brittleness of the sample, while normal stress will inhibit these effect. Under low/high normal stress, the sample show two failure modes, at the meso-damage level: elastic-shearing-frictional sliding and elastic-extrusion wear. This is mainly controlled by the contact and friction state of the material after damage. The secondary failure of undulating structure under normal-shear stress is the nature of extrusion wear, which is positively correlated to the normal stress and the degree of difference in mechanical properties of different materials. The increase of the mechanical difference of the sample will enhance the shear brittleness under lower normal stress and the shear interaction under higher normal stress.

Shear Strength of Beam-Column eoints Using High-Strength Concrete (고강도콘크리트를 사용한 보-기둥 접합부의 전단강도)

  • 장극관;서대원
    • Journal of the Korea Concrete Institute
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    • v.12 no.2
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    • pp.53-62
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    • 2000
  • Under severe lateral loads, ductile moments-resisting reinforced concrete frames will be subjected to large loads and displacements. Thus, large deformation and shear stree are occurred at the beam-column joints which are the most critical region in ductile moments-resisting system. The purpose of this study was to investigate the shear strength of beam-column connection using high strength concrete. Four subassemblies were designed 2/3 scale of read structures and tested. The obtained results are as follows. 1) The transverse beams increase the shear resistance and ductility of joint, 2) The slab was contributed to increase of the flexural capacity of the beam, but was not contributed to increase the joint ductility under cyclic loads. 3) The shear stress factors. given by the ACI code would be modified in evaluating the shear strength of beam-column joints of frame which were constructed with high-strength concrete.

Evaluation of Resilient Modulus Models for Recycled Materials (재활용 도로재료의 회복탄성계수 산정을 위한 적용 모델의 평가)

  • Son, Young-Hwan
    • Journal of The Korean Society of Agricultural Engineers
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    • v.52 no.2
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    • pp.51-57
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    • 2010
  • Many models have been used to represent the effects of confining stress, bulk stress, and shear stress on the value of the resilient modulus (Mr). This study was conducted to estimate Mr of the recycled materials such as recycled concrete aggregate (RCA) and recycled asphalt pavement (RAP) through the repeated load cyclic test. Also, two models were applied to estimation of Mr for comparing between measured Mr values and predicted Mr values. The first model (A-model) can provide a quick and easy estimation of the Mr based on the bulk stress, while the second model (N-model) includes not only the bulk stress but also the shear stress. Statistical analysis indicated that all results using the both of models are significant at a 95 % confidence level. Therefore, the both of models could be used as an effective prediction model of Mr for RCA and RAP. Especially, the Model 2 including the parameters of the bulk stress and the shear stress could give more reliable estimation at the high range of Mr values.