• Title/Summary/Keyword: Hierarchical Bayesian analysis

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Statistical Method for Implementing the Experimenter Effect in the Analysis of Gene Expression Data

  • Kim, In-Young;Rha, Sun-Young;Kim, Byung-Soo
    • Communications for Statistical Applications and Methods
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    • v.13 no.3
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    • pp.701-718
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    • 2006
  • In cancer microarray experiments, the experimenter or patient which is nested in each experimenter often shows quite heterogeneous error variability, which should be estimated for identifying a source of variation. Our study describes a Bayesian method which utilizes clinical information for identifying a set of DE genes for the class of subtypes as well as assesses and examines the experimenter effect and patient effect which is nested in each experimenter as a source of variation. We propose a Bayesian multilevel mixed effect model based on analysis of covariance (ANACOVA). The Bayesian multilevel mixed effect model is a combination of the multilevel mixed effect model and the Bayesian hierarchical model, which provides a flexible way of defining a suitable correlation structure among genes.

Robust Bayesian Models for Meta-Analysis

  • Kim, Dal-Ho;Park, Gea-Joo
    • Journal of the Korean Data and Information Science Society
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    • v.11 no.2
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    • pp.313-318
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    • 2000
  • This article addresses aspects of combining information, with special attention to meta-analysis. In specific, we consider hierarchical Bayesian models for meta-analysis under priors which are scale mixtures of normal, and thus have tail heavier than that of the normal. Numerical methods of finding Bayes estimators under these heavy tailed prior are given, and are illustrated with an actual example.

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Development of Hierarchical Bayesian Spatial Regional Frequency Analysis Model Considering Geographical Characteristics (지형특성을 활용한 계층적 Bayesian Spatial 지역빈도해석)

  • Kim, Jin-Young;Kwon, Hyun-Han;Lim, Jeong-Yeul
    • Journal of Korea Water Resources Association
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    • v.47 no.5
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    • pp.469-482
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    • 2014
  • This study developed a Bayesian spatial regional frequency analysis, which aimed to analyze spatial patterns of design rainfall by incorporating geographical information (e.g. latitude, longitude and altitude) and climate characteristics (e.g. annual maximum series) within a Bayesian framework. There are disadvantages to considering geographical characteristics and to increasing uncertainties associated with areal rainfall estimation on the existing regional frequency analysis. In this sense, this study estimated the parameters of Gumbel distribution which is a function of geographical and climate characteristics, and the estimated parameters were spatially interpolated to derive design rainfall over the entire Han-river watershed. The proposed Bayesian spatial regional frequency analysis model showed similar results compared to L-moment based regional frequency analysis, and even better performance in terms of quantifying uncertainty of design rainfall and considering geographical information as a predictor.

A Development of Regional Frequency Model Based on Hierarchical Bayesian Model (계층적 Bayesian 모형 기반 지역빈도해석 모형 개발)

  • Kwon, Hyun-Han;Kim, Jin-Young;Kim, Oon-Ki;Lee, Jeong-Ju
    • Journal of Korea Water Resources Association
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    • v.46 no.1
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    • pp.13-24
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    • 2013
  • The main objective of this study was to develop a new regional frequency analysis model based on hierarchical Bayesian model that allows us to better estimate and quantify model parameters as well as their associated uncertainties. A Monte-carlo experiment procedure has been set up to verify the proposed regional frequency analysis. It was found that the proposed hierarchical Bayesian model based regional frequency analysis outperformed the existing L-moment based regional frequency analysis in terms of reducing biases associated with the model parameters. Especially, the bias is remarkably decreased with increasing return period. The proposed model was applied to six weather stations in Jeollabuk-do, and compared with the existing L-moment approach. This study also provided shrinkage process of the model parameters that is a typical behavior in hierarchical Bayes models. The results of case study show that the proposed model has the potential to obtain reliable estimates of the parameters and quantitatively provide their uncertainties.

Assessment of Effects of Predictors on the Corporate Bankruptcy Using Hierarchical Bayesian Dynamic Model

  • Sung Min-Je;Cho Sung-Bin
    • Management Science and Financial Engineering
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    • v.12 no.1
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    • pp.65-77
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    • 2006
  • This study proposes a Bayesian dynamic model in a hierarchical way to assess the time-varying effect of risk factors on the likelihood of corporate bankruptcy. For the longitudinal data, we aim to describe dynamically evolving effects of covariates more articulately compared to the Generalized Estimating Equation approach. In the analysis, it is shown that the proposed model outperforms in terms of sensitivity and specificity. Besides, the usefulness of this study can be found from the flexibility in describing the dependence structure among time specific parameters and suitability for assessing the time effect of risk factors.

A development of hierarchical bayesian model for changing point analysis at watershed scale (유역단위에서의 연강수량의 변동점 분석을 위한 계층적 Bayesian 분석기법 개발)

  • Kim, Jin-Guk;Kim, Jin-Young;Kim, Yoon-Hee;Kwon, Hyun-Han
    • Journal of Korea Water Resources Association
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    • v.50 no.2
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    • pp.75-87
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    • 2017
  • In recent decades, extreme events have been significantly increased over the Korean Peninsula due to climate variability and climate change. The potential changes in hydrologic cycle associated with the extreme events increase uncertainty in water resources planning and designing. For these reasons, a reliable changing point analysis is generally required to better understand regime changes in hydrologic time series at watershed scale. In this study, a hierarchical changing point analysis approach that can apply in a watershed scale is developed by combining the existing changing point analysis method and hierarchical Bayesian method. The proposed model was applied to the selected stations that have annual rainfall data longer than 40 years. The results showed that the proposed model can quantitatively detect the shift in precipitation in the middle of 1990s and identify the increase in annual precipitation compared to the several decades prior to the 1990s. Finally, we explored the changes in precipitation and sea level pressure in the context of large-scale climate anomalies using reanalysis data, for a given change point. It was concluded that the identified large-scale patterns were substantially different from each other.

Robust Bayesian meta analysis (로버스트 베이지안 메타분석)

  • Choi, Seong-Mi;Kim, Dal-Ho;Shin, Im-Hee;Kim, Ho-Gak;Kim, Sang-Gyung
    • Journal of the Korean Data and Information Science Society
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    • v.22 no.3
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    • pp.459-466
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    • 2011
  • This article addresses robust Bayesian modeling for meta analysis which derives general conclusion by combining independently performed individual studies. Specifically, we propose hierarchical Bayesian models with unknown variances for meta analysis under priors which are scale mixtures of normal, and thus have tail heavier than that of the normal. For the numerical analysis, we use the Gibbs sampler for calculating Bayesian estimators and illustrate the proposed methods using actual data.

Bayesian Hierarchical Mixed Effects Analysis of Time Non-Homogeneous Markov Chains (계층적 베이지안 혼합 효과 모델을 사용한 비동차 마코프 체인의 분석)

  • Sung, Minje
    • The Korean Journal of Applied Statistics
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    • v.27 no.2
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    • pp.263-275
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    • 2014
  • The present study used a hierarchical Bayesian approach was used to develop a mixed effect model to describe the transitional behavior of subjects in time nonhomogeneous Markov chains. The posterior distributions of model parameters were not in analytically tractable forms; subsequently, a Gibbs sampling method was used to draw samples from full conditional posterior distributions. The proposed model was implemented with real data.

Evaluations of Small Area Estimations with/without Spatial Terms (공간 통계 활용에 따른 소지역 추정법의 평가)

  • Shin, Key-Il;Choi, Bong-Ho;Lee, Sang-Eun
    • The Korean Journal of Applied Statistics
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    • v.20 no.2
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    • pp.229-244
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    • 2007
  • Among the small area estimation methods, it has been known that hierarchical Bayesian(HB) approach is the most reasonable and effective method. However any model based approaches need good explanatory variables and finding them is the key role in the model based approach. As the lacking of explanatory variables, adopting the spatial terms in the model was introduced. Here in this paper, we evaluate the model based methods with/without spatial terms using the diagnostic methods which were introduced by Brown et al. (2001). And Economic Active Population Survey(2005) is used for data analysis.